Melanin production inhibitor
    11.
    发明授权
    Melanin production inhibitor 有权
    黑色素生成抑制剂

    公开(公告)号:US08846012B2

    公开(公告)日:2014-09-30

    申请号:US13131827

    申请日:2009-12-22

    摘要: Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor is represented by general formula (1) (excluding clotrimazole) and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent. At least one of A1, A2 and A3 is selected from the aryl group and the aromatic heterocyclic group, the total number of carbon atoms contained in A1, A2 and A3 is 6 to 50 and, when at least two of A1, A2 and A3 represent the aryl groups or the aromatic heterocyclic groups, the adjacent two aryl or aromatic heterocyclic groups may be bound to each other via an alkyl chain or an alkenyl chain to form a ring; m represents an integer of 0 to 2; X represents a hetero atom, a hydrogen atom, or a carbon atom; R1 and R2 are independently selected from a hydrogen atom and an oxo group. When one of R1 and R2 is an oxo group, the other is not present. R3 is selected from a hydrogen atom, and a C1-8 hydrocarbon group in which one or some of hydrogen atoms or carbon atoms may be substituted by a hetero atom or hetero atoms. The number of R3's present in the compound corresponds to X and, when two or more R3's are present, the R3's are independently present and the adjacent two R3's may be bound to each other to form, together with X, a ring, and the terminal of R3 may be bound to a carbon atom to which A1, A2 and A3 are bound, thereby forming a ring.

    摘要翻译: 公开了一种黑色素产生抑制剂,其对黑色素的生成具有优异的抑制活性,并且是高度安全的。 黑色素产生抑制剂由通式(1)表示(不包括克霉唑)和/或其药理学上可接受的盐。 在该式中,A1,A2和A3独立地选自氢原子,可以具有取代基的芳基和可以具有取代基的芳族杂环基。 A1,A2和A3中的至少一个选自芳基和芳族杂环基,A1,A2和A3中所含的碳原子总数为6〜50,A1,A2和A3中的至少2个 表示芳基或芳族杂环基,相邻的两个芳基或芳族杂环基可以通过烷基链或烯基链彼此结合形成环; m表示0〜2的整数。 X表示杂原子,氢原子或碳原子; R 1和R 2独立地选自氢原子和氧代基。 当R1和R2中的一个是氧代基时,另一个不存在。 R3选自氢原子和碳原子数为1〜8的烃基,其中一个或几个氢原子或碳原子可以被杂原子或杂原子取代。 化合物中存在的R3的数目对应于X,并且当存在两个或更多个R 3时,R 3独立地存在,并且相邻的两个R 3可以彼此结合形成与X一起形成环,并且末端 的R3可以结合到与A1,A2和A3结合的碳原子上,从而形成环。

    Contact device
    13.
    发明授权
    Contact device 有权
    联系设备

    公开(公告)号:US07046107B2

    公开(公告)日:2006-05-16

    申请号:US10511136

    申请日:2004-02-27

    IPC分类号: H01H67/02

    摘要: Each movable contact 15 is given a first force by a drive mechanism along a direction for bringing the movable contact into contact with a fixed contact 5 and given a second force through a leg 14b by deformation of a supporting member 14c resulted from an overtravel of the movable plate 14. The fixed contact and the movable contact are arranged such that a resultant force of the first and the second forces acts in a direction normal to a contact surface defined between the fixed contacts and the movable contacts. So, a component force of the resultant force parallel to the contact surface is not generated, therefore, a side slip of the movable contact can be prevented when the contacts are opened or closed.

    摘要翻译: 通过驱动机构沿着使可动触点与固定触点5接触的方向,通过驱动机构给予每个可动触头15的第一力,并且通过由过行程导致的支撑构件14c的变形而通过腿部14b施加第二力 的可动板14。 固定触点和可动触头被布置成使得第一和第二力的合力沿垂直于限定在固定触点和可动触点之间的接触表面的方向作用。 因此,不会产生与接触面平行的合力的分力,因此,当触点打开或闭合时,可以防止可动触点的侧滑。

    Contact-point device
    14.
    发明申请
    Contact-point device 有权
    接点设备

    公开(公告)号:US20050190025A1

    公开(公告)日:2005-09-01

    申请号:US10511136

    申请日:2004-02-27

    摘要: Each movable contact 15 is given a first force by a drive mechanism along a direction for bringing the movable contact into contact with a fixed contact 5 and given a second force through a leg 14b by deformation of a supporting member 14c resulted from an overtravel of the movable plate 14. The fixed contact and the movable contact are arranged such that a resultant force of the first and the second forces acts in a direction normal to a contact surface defined between the fixed contacts and the movable contacts. So, a component force of the resultant force parallel to the contact surface is not generated, therefore, a side slip of the movable contact can be prevented when the contacts are opened or closed.

    摘要翻译: 通过驱动机构沿着使可动触点与固定触点5接触的方向,通过驱动机构给予每个可动触头15的第一力,并且通过由过行程导致的支撑构件14c的变形而通过腿部14b施加第二力 的可动板14。 固定触点和可动触头被布置成使得第一和第二力的合力沿垂直于限定在固定触点和可动触点之间的接触表面的方向作用。 因此,不会产生与接触面平行的合力的分力,因此,当触点打开或闭合时,可以防止可动触点的侧滑。

    Contact structure, an apparatus having the contact structure and image input apparatus having the contact structure
    15.
    发明申请
    Contact structure, an apparatus having the contact structure and image input apparatus having the contact structure 有权
    接触结构,具有接触结构的设备和具有接触结构的图像输入设备

    公开(公告)号:US20050020126A1

    公开(公告)日:2005-01-27

    申请号:US10863200

    申请日:2004-06-09

    摘要: A contact structure having a spring with electro conductivity. The spring is fixed at one inner end side of a battery housing by engaging a plurality of inflection parts of the spring to one end side of the battery housing. The spring urges the battery to the other end side of a battery housing. An end portion on movable side end of the spring is extended toward an opening on a lateral face of the battery housing. The end portion is formed on a contact side end of the spring that is contacted with the battery, and is connected to one end side of a bypassing lead wire. An end portion on the fixed side end of the spring is connected to the other end side of the bypassing lead wire. The end portion of the fixed side end of the spring is connected to a power source lead wire.

    摘要翻译: 具有导电弹簧的接触结构。 弹簧通过将弹簧的多个弯曲部分接合到电池壳体的一端侧而固定在电池壳体的一个内端侧。 弹簧将电池推向电池壳体的另一端。 弹簧的可动侧端部的端部朝向电池壳体的侧面上的开口延伸。 端部形成在与电池接触的弹簧的接触侧端部,并且连接到旁路引线的一端侧。 弹簧的固定侧端部的端部与旁路引线的另一端侧连接。 弹簧的固定侧端的端部连接到电源引线。