公开(公告)号：US20240277991A1

公开(公告)日：2024-08-22

申请号：US18640260

申请日：2024-04-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/237 ,  A61M60/419 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829

CPC classification number: A61M60/178 ,  A61M60/237 ,  A61M60/419 ,  A61M60/531 ,  A61M60/818 ,  A61M60/829

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a left ventricle of a subject, and an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood from the left ventricle. A frame surrounds the impeller and a tip portion is coupled to a distal end of the frame. The tip portion includes a distal curved portion, which, when deployed within the left ventricle, lies in a plane, and a proximal curved portion, which, when deployed within the left ventricle, does not lie in the plane and is curved such that, following the insertion of the axial shaft into the left ventricle via an aorta of the subject, a distal end of the proximal curved portion points toward an apex of the left ventricle. Other applications are also described.

公开(公告)号：US20240261561A1

公开(公告)日：2024-08-08

申请号：US18632569

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/226 ,  A61M60/419 ,  A61M60/531 ,  A61M60/538 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC classification number: A61M60/178 ,  A61M60/226 ,  A61M60/419 ,  A61M60/531 ,  A61M60/538 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more blood-outlet openings and including a narrower section, and a wider section, which is proximal to and wider than the narrower section, and which is shaped to define at least a portion of each of the blood-outlet openings such that a normal vector to the portion has a distally-facing component. The pump-outlet tube is inserted, through the subject's aorta, into the subject's left ventricle such that the pump-outlet tube traverses an aortic valve of the subject with the blood-outlet openings being disposed within the aorta. An impeller is disposed within the narrower section of the pump-outlet tube and is configured to pump blood of the subject, through the blood-outlet openings, from the left ventricle into the aorta. Other applications are also described.

公开(公告)号：US20250073445A1

公开(公告)日：2025-03-06

申请号：US18933745

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/216 ,  A61M60/122 ,  A61M60/414 ,  A61M60/825 ,  A61M60/90

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body. The blood pump also includes an impeller coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. Proximal and distal radial bearings surround the axial shaft and are configured to radially stabilize the axial shaft while the axial shaft rotates. Proximal and distal sleeves, which are less flexible than the axial shaft, are disposed around the axial shaft, such that the proximal and distal sleeves contact the proximal and distal radial bearings, respectively, as the axial shaft rotates. A ratio between a length of the axial shaft and a combined length of the proximal sleeve and distal sleeve is between 2:1 and 6:1. Other applications are also described.

公开(公告)号：US20240285928A1

公开(公告)日：2024-08-29

申请号：US18635292

申请日：2024-04-15

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/237 ,  A61M60/174 ,  A61M60/857

CPC classification number: A61M60/237 ,  A61M60/174 ,  A61M60/857

Abstract: Apparatus and methods are provided, including inserting an impeller and a delivery tube into a subject's body, the delivery tube including a braid having a pick density that varies along the delivery tube's length such that a flexural rigidity of the delivery tube at a first portion of the delivery tube is less than the flexural rigidity at a second portion of the delivery tube, and the flexural rigidity at the second portion is less than the flexural rigidity at a third portion of the delivery tube. The impeller and delivery tube are positioned such that the impeller is disposed within the subject's left ventricle and the delivery tube passes the subject's aorta into the left ventricle. Using a drive cable, which passes through the delivery tube, the impeller is rotated so as to pump blood from the left ventricle into the aorta. Other applications are also described.

公开(公告)号：US20240277999A1

公开(公告)日：2024-08-22

申请号：US18639094

申请日：2024-04-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/825 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/865

CPC classification number: A61M60/825 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/865

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion, over a guidewire, into a subject's body, and for rotation within the subject's body. The axial shaft is shaped to define a shaft lumen for passage of the guidewire therethrough. An impeller is coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A thrust bearing is disposed distally from the axial shaft so as to inhibit distal movement of the axial shaft beyond the thrust bearing. The thrust bearing is shaped to define a bearing lumen that is configured to be continuous with the shaft lumen. At least a portion of the bearing lumen is frustoconically-shaped, a wider end of the frustoconically-shaped portion of the bearing lumen facing distally. Other applications are also described.

公开(公告)号：US20240261565A1

公开(公告)日：2024-08-08

申请号：US18637667

申请日：2024-04-17

Applicant: MAGENTA MEDICAL LTD

Inventor： Yuri TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/859 ,  A61L29/02 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/859 ,  A61L29/02 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/414 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825

Abstract: Apparatus and methods are described including an axial shaft configured for insertion into, and rotation within, a subject's body. A delivery tube extends to the axial shaft, from outside the subject's body, while the axial shaft is within the subject's body. An impeller is coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. Proximal and distal radial bearings surround the axial shaft, proximally and distally to the impeller respectively, the proximal and distal radial bearings being configured to radially stabilize the axial shaft while the axial shaft rotates. A proximal bearing housing houses the proximal radial bearing and is coupled to the delivery tube. A drive cable rotates the axial shaft while extending through the delivery tube, and is coupled to the axial shaft within the proximal bearing housing. Other applications are also described.

公开(公告)号：US20240252808A1

公开(公告)日：2024-08-01

申请号：US18632557

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/216 ,  A61M60/295 ,  A61M60/408 ,  A61M60/818

CPC classification number: A61M60/178 ,  A61M60/216 ,  A61M60/295 ,  A61M60/408 ,  A61M60/818

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more laterally-facing blood-outlet openings and including a first section and a second section that overlap one another between the laterally-facing blood-outlet openings. The pump-outlet tube is configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that the pump-outlet tube traverses an aortic valve of the subject with the lateral blood-outlet openings being disposed within the aorta. An impeller is disposed within the first section of the pump-outlet tube and is configured to pump blood of the subject, through the laterally-facing blood-outlet openings, from the left ventricle into the aorta. Other applications are also described.

公开(公告)号：US20250010060A1

公开(公告)日：2025-01-09

申请号：US18889744

申请日：2024-09-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/17 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/237 ,  A61M60/242 ,  A61M60/295 ,  A61M60/408 ,  A61M60/414 ,  A61M60/419 ,  A61M60/497 ,  A61M60/508 ,  A61M60/531 ,  A61M60/538 ,  A61M60/554 ,  A61M60/585 ,  A61M60/806 ,  A61M60/808 ,  A61M60/81 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/859 ,  A61M60/865

Abstract: Apparatus and methods are described including a blood pump that includes a pump-outlet tube shaped to define one or more blood-outlet openings and configured for insertion into a heart of a subject. An impeller is disposed within a distal portion of the pump-outlet tube and is configured to pump blood of the subject proximally through the pump-outlet tube, such that the blood exits the pump-outlet tube through the blood-outlet openings. A delivery tube extends, from outside a body of the subject, through the pump-outlet tube to the distal portion. A drive cable passes through the delivery tube and is configured to rotate the impeller. A proximal portion of the pump-outlet tube includes multiple strips adhered to the delivery tube. Other embodiments are also described.

公开(公告)号：US20240359000A1

公开(公告)日：2024-10-31

申请号：US18639087

申请日：2024-04-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/818 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829

CPC classification number: A61M60/818 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829 ,  A61M2205/0211 ,  A61M2205/0222 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/502

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a body of a subject. An impeller is coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A thrust bearing includes a proximally-facing ceramic surface disposed distally from the axial shaft so as to inhibit distal movement of the axial shaft beyond the thrust bearing, and a distally-facing ceramic cover that covers a distal end of the axial shaft, such that the ceramic cover contacts the ceramic surface as the axial shaft rotates. Other applications are also described.

公开(公告)号：US20240342464A1

公开(公告)日：2024-10-17

申请号：US18632545

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/508 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81

CPC classification number: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/508 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M2205/103 ,  A61M2205/502 ,  A61M2210/125

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more blood-outlet openings and configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that the pump-outlet tube traverses an aortic valve of the subject with the blood-outlet openings being disposed within the aorta. A blood pump is disposed at least partly within a distal portion of the pump-outlet tube and is configured to pump blood of the subject proximally through the pump-outlet tube. A proximal end of the pump-outlet tube is folded inwardly so as to define one or more surfaces configured to direct the blood through the blood-outlet openings by virtue of being oblique with respect to a longitudinal axis of the pump-outlet tube. Other applications are also described.