Identification of a new AMPK activator for treatment of lung cancer
    11.
    发明授权
    Identification of a new AMPK activator for treatment of lung cancer 有权
    鉴定用于治疗肺癌的新的AMPK激活剂

    公开(公告)号:US09364469B1

    公开(公告)日:2016-06-14

    申请号:US14925996

    申请日:2015-10-29

    CPC classification number: A61K31/4439

    Abstract: The present invention discloses a method of treating gefitinib-resistant non-small-cell lung cancer, comprising administering an effective amount of D561-0775. A pharmaceutical composition comprising D561-0775 admixed with a pharmaceutical carrier for treating Gefitinib-resistant non-small-cell lung cancer is also disclosed therein.

    Abstract translation: 本发明公开了一种治疗耐吉非替尼的非小细胞肺癌的方法,包括给予有效量的D561-0775。 还公开了包含D561-0775的药物组合物,其与药物载体混合以治疗吉非替尼耐药性非小细胞肺癌。

    Neferine and the use thereof in treating huntington disease
    16.
    发明授权
    Neferine and the use thereof in treating huntington disease 有权
    奈非炔及其在治疗亨廷顿疾病中的应用

    公开(公告)号:US09119847B2

    公开(公告)日:2015-09-01

    申请号:US14562780

    申请日:2014-12-08

    CPC classification number: A61K31/4725 A61K36/62

    Abstract: The present invention discloses a method of treating neurodegenerative disorder comprising administering an effective amount of an alkaloid which is a bisbenzylisoquinline alkaloid isolated from the traditional Chinese medicinal herb Nelumbo nucifera. The pharmaceutical composition thereof for treating Huntington's disease is also disclosed.

    Abstract translation: 本发明公开了一种治疗神经变性疾病的方法,包括给予有效量的生物碱,所述生物碱是从中草药Nelumbo Nucumera分离的双苄基异喹啉生物碱。 还公开了其用于治疗亨廷顿病的药物组合物。

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