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公开(公告)号：US12023084B2
公开(公告)日：2024-07-02
申请号：US17577775
申请日：2022-01-18
Applicant: Medtronic, Inc.
Inventor： Brian T. Howard , Steven J. Fraasch , Mark T. Stewart , John Vandanacker
CPC classification number: A61B18/1206 , A61B18/14 , A61N1/327 , G06F30/20 , A61B2018/00357 , A61B2018/00613 , A61B2018/0075 , A61B2018/00761 , A61B2018/00767 , A61B2018/00779 , A61B2018/00791 , A61B2018/00827 , A61B2018/00839 , A61B2018/00875 , A61B2018/00892 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1467 , A61B18/1492
Abstract: A method of determining a pulsed field ablation waveform parameter for creating a desired lesion characteristic in cardiac tissue. The method of provides an electrosurgical generator configured to deliver electroporation pulses, the generator configured to: load predetermined waveform parameters (yi); load predetermined modeling data (xi); accept entry of a user inputted desired lesion characteristic (ui); and determine at least one corresponding pulsed field ablation waveform parameter based on (ui), (yi); and (xi).
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公开(公告)号：US20220296295A1
公开(公告)日：2022-09-22
申请号：US17697523
申请日：2022-03-17
Applicant: Medtronic, Inc.
Inventor： Brian T. Howard , Timothy G. Laske , Kenneth C. Gardeski , Gonzalo Martinez , Mark T. Stewart , Lars M. Mattison
Abstract: A medical device including an elongate body having a proximal portion and a distal portion. A plurality of active electrodes is coupled to the distal portion of the elongate body and being configured to electrically couple to a source of pulsed electric field energy. At least one passive electrode is coupled to the elongate body and is not configured to electrically couple to the source of pulsed electric field energy, the at least one passive electrode being configured to passively extend or focus an electric field generated by the plurality of active electrodes.
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公开(公告)号：US20220273353A1
公开(公告)日：2022-09-01
申请号：US17678102
申请日：2022-02-23
Applicant: Medtronic, Inc.
Inventor： Brian T. Howard , Megan M. Schmidt , Lars M. Mattison
Abstract: A method and a medical device for determining efficacy of a pulsed electric field (PEF) ablation procedure are disclosed. According to one aspect, the method includes generating at least one pulsed electric field (PEF) pulse to be delivered to at least one electrode of a plurality of electrodes, the at least one electrode being at a distal end of a PEF ablation catheter and being positionable in proximity to a target region of tissue to be ablated. The method also includes determining an index of completeness indicative of a completeness of ablation of the target region of tissue based at least in part on a change in a parameter compared to an expected change in the parameter, the change in the parameter being caused at least in part on an extent of ablation of the target region.
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公开(公告)号：US20220241009A1
公开(公告)日：2022-08-04
申请号：US17584770
申请日：2022-01-26
Applicant: Medtronic, Inc.
Inventor： Brian T. Howard , Timothy G. Laske , Gregory Scott Brumfield
IPC: A61B18/14
Abstract: A medical device is configured to deliver pulsed electric field (PEF) energy to tissue and includes an elongated shaft having a proximal portion and a distal portion. A balloon is coupled to the distal portion of the elongated shaft. A plurality of electrodes is disposed on an outer surface of the balloon and configured to apply PEF energy to tissue. The balloon defines one or more irrigation channels proximate to or on the plurality of electrodes, the one or more irrigation channels being configured to irrigate at least one of the plurality of electrodes.
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公开(公告)号：US11364072B2
公开(公告)日：2022-06-21
申请号：US15418325
申请日：2017-01-27
Applicant: Medtronic, Inc.
Inventor： Brian T. Howard , Mark T. Stewart , Damijan Miklav{hacek over (c)}i{hacek over (c)} , Bushan K. Purushothaman , Jeremy M. Stimack
Abstract: Methods, systems, and devices for enhancing the efficiency and efficacy of energy delivery and tissue mapping. One system includes a treatment element having a plurality of electrodes and an energy generator that is configured to deliver electric energy pulses to the electrodes in a variety of patterns. For example, electrodes may be arranged in closely spaced pairs. The energy generator may deliver mapping energy to each electrode in each pair individually to map tissue and may deliver ablation energy to the electrodes in each pair together, such that each pair is treated like a single electrode, to deliver ablation energy, such as bipolar ablation energy between adjacent pairs. One system includes at least one concave electrode, the configuration of which concentrates the energy and drives it deeper into the tissue. One system includes neutral electrodes between active electrodes, the energy generator selectively coupling the neutral electrodes to alter the ablation pattern.
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Patent Agency Ranking
公开(公告)号：US11052246B2
公开(公告)日：2021-07-06
申请号：US15663301
申请日：2017-07-28
Applicant: Medtronic, Inc.
Inventor： Mark T. Stewart , Brian T. Howard
IPC: A61N1/32 , A61N1/30 , A61B18/14 , A61N1/378 , A61N1/05 , A61B18/00 , A61B18/12 , A61B18/02 , A61B17/00
Abstract: A method, system, and device for electroporation. A system may include a medical device with a plurality of electrodes borne on an expandable element and an energy generator in communication with the electrodes. The energy generator may have processing circuitry configured to selectively deliver electroporation energy to at least one of the electrodes. The processing circuitry may determine whether an alert condition is present and, if so, cease the delivery of electroporation energy to one or more electrodes identified as the cause of the alert condition and/or prevent the delivery of electroporation energy to the one or more electrodes identified as the cause of the alert condition. The energy generator may also be configured to deliver electroporation energy in a sequence of a plurality of energy delivery patterns to enhance lesion formation.
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公开(公告)号：US10849677B2
公开(公告)日：2020-12-01
申请号：US15418217
申请日：2017-01-27
Applicant: Medtronic, Inc.
Inventor： Steven J. Fraasch , Catherine R. Condie , Brian T. Howard , Louis Jacob , Paul S. Lam , Trenton J. Rehberger , Mark T. Stewart , Qin Zhang
IPC: A61B18/12 , A61B5/042 , A61B5/0452 , A61B5/0456 , A61B5/00 , A61B18/14 , A61N1/30 , H02H1/00 , H02H3/16 , A61B18/00 , A61B18/16
Abstract: A system and method for the safe delivery of treatment energy to a patient, which includes verification of system integrity before, during, or after the delivery of treatment energy and provides several mechanisms for rapid termination of the delivery of potentially harmful energy to the patient when a fault condition in the device and/or system is identified. The system may include an energy generator having processing circuitry to determine if there is a fault condition in the system and to automatically terminate a delivery of treatment energy when the processing circuitry determines there is a fault condition. The method may generally include performing a series of pre-checks, synchronizing a treatment energy delivery to the proper segment of the heart's depolarization pattern, configuring the system for treatment energy delivery, delivering the treatment energy, and performing post-treatment evaluation.
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公开(公告)号：US12127778B2
公开(公告)日：2024-10-29
申请号：US16263812
申请日：2019-01-31
Applicant: Medtronic, Inc.
Inventor： Mark T. Stewart , Brian T. Howard
CPC classification number: A61B18/1206 , A61B18/14 , A61B18/1492 , A61B2018/00214 , A61B2018/00351 , A61B2018/00363 , A61B2018/00577 , A61B2018/00613 , A61B2018/00744 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/00892 , A61B2018/126 , A61B2018/1472 , A61B2218/002 , A61B2218/007
Abstract: Devices, systems, and methods for more efficiently ablating tissue with pulsed field ablation energy while minimizing collateral injury to non-target tissue. In one embodiment, a system for ablating tissue at a treatment site comprises: an energy delivery device; and a control unit including: a source of impedance-modifying fluid in fluid communication with the energy delivery device; an energy generator in electrical communication with the energy delivery device, the energy generator being configured to transmit energy to the energy delivery device and the energy delivery device being configured to deliver energy to the treatment site; and processing circuitry configured to control delivery of the impedance-modifying fluid from the energy delivery device to the treatment site. In one embodiment, a method for ablating tissue comprises delivering an impedance-modifying fluid to a treatment site and delivering pulsed field ablation energy to the treatment site.
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公开(公告)号：US20240341833A1
公开(公告)日：2024-10-17
申请号：US18756131
申请日：2024-06-27
Applicant: Medtronic, Inc.
Inventor： Brian T. Howard , Steven J. Fraasch , Mark T. Stewart , John Vandanacker
CPC classification number: A61B18/1206 , A61B18/14 , A61N1/327 , G06F30/20 , A61B2018/00357 , A61B2018/00613 , A61B2018/0075 , A61B2018/00761 , A61B2018/00767 , A61B2018/00779 , A61B2018/00791 , A61B2018/00827 , A61B2018/00839 , A61B2018/00875 , A61B2018/00892 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1467 , A61B18/1492
Abstract: A pulsed field ablation medical device. Among other things, the medical device includes processing circuitry in communication with an electrosurgical generator and a plurality of electrodes. In one example, the processing circuitry is configured to determine a desired lesion characteristic; determine a first waveform parameter based on the desired lesion characteristic; deliver, via the plurality of electrodes, a first pulsed field waveform of the plurality of pulsed field waveforms based on the first waveform parameter to ablate the area of tissue; measure a second lesion characteristic based on a result of delivering the first pulsed field waveform; determine a second waveform parameter based on the second lesion characteristic; deliver, via the plurality of electrodes, a second pulsed field waveform of the plurality of pulsed field waveforms based on the second waveform parameter to ablate the area of tissue.
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公开(公告)号：US20230414277A1
公开(公告)日：2023-12-28
申请号：US18338762
申请日：2023-06-21
Applicant: Medtronic, Inc.
Inventor： Brian J. Kelly , Gavin J. Kenny , Brian T. Howard , Timothy G. Laske , Andrzej M. Malewicz , Mark T. Stewart
IPC: A61B18/14
CPC classification number: A61B18/1492 , A61B2018/00083
Abstract: A medical device includes an elongate body, an expandable treatment element, a plurality of flexible shafts, and a plurality of electrodes. The elongate body has a proximal portion and a distal portion opposite the proximal portion. The expandable treatment element is coupled to the elongate body to receive a fluid and, in some examples, is anchored to the plurality of flexible shafts with a plurality of retention elements. In some examples, each flexible shaft of the plurality of flexible shafts has a braided configuration. Each electrode of the plurality of electrodes is attached and electrically coupled to a respective flexible shaft of the plurality of flexible shafts.
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