公开(公告)号：US20160302921A1

公开(公告)日：2016-10-20

申请号：US14687295

申请日：2015-04-15

Applicant: Medtronic, Inc.

Inventor： Devin Gosal ,  Susheel Deshmukh ,  Philip Haarstad ,  Joel Racchini ,  Finn Rinne ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

CPC classification number: A61F2/2427 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2002/9522 ,  A61F2230/001 ,  A61F2250/0039

Abstract: A system for percutaneous delivery of a stented prosthetic heart valve. The system includes a delivery device with a self-expanding prosthetic heart valve attached thereto and a delivery sheath with an opening on a distal end thereof. The delivery sheath includes a funnel on a proximal end thereof. The delivery device is inserted into the funnel of the delivery sheath. As the delivery device is advanced into the funnel, the expanded heart valve is compressed by the shape of the funnel into a crimped arrangement. The delivery device further advances the heart valve distally within the delivery sheath past the delivery sheath opening. The delivery device is advanced relative to the delivery sheath in transitioning the heart valve from a crimped arrangement to the expanded and deployed arrangement.

Abstract translation: 用于经皮输送支架假体心脏瓣膜的系统。 该系统包括具有附接到其上的自扩张假体心脏瓣膜的输送装置和在其远端具有开口的输送护套。 输送护套在其近端包括漏斗。 输送装置插入输送鞘的漏斗中。 当输送装置进入漏斗时，扩张的心脏瓣膜通过漏斗的形状被压缩成卷曲的布置。 输送装置进一步使输送护套内的心脏瓣膜远离输送护套开口。 输送装置相对于输送护套前进，将心脏瓣膜从卷曲布置转换到扩张和展开的布置。

公开(公告)号：US20160151153A1

公开(公告)日：2016-06-02

申请号：US14556484

申请日：2014-12-01

Applicant: Medtronic, Inc.

Inventor： Jeffrey Sandstrom ,  Alaena Maiorano ,  Joel Racchini

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/07 ,  A61F2/24 ,  A61F2/2412 ,  A61F2/2436 ,  A61F2002/828 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008 ,  A61F2250/0039

Abstract: Embodiments hereof relate to a transcatheter valve prosthesis including a tubular fabric body, a first or inflow tubular scaffold attached to a first end portion of the tubular fabric body, and a second or outflow tubular scaffold attached to a second end portion of the tubular fabric body. A prosthetic valve component is disposed within and secured to an intermediate portion of the tubular fabric body that longitudinally extends between the first and second end portions of the tubular fabric body. The intermediate portion is unsupported such that neither of the first and second tubular scaffolds surrounds the intermediate portion of the tubular fabric body. The intermediate portion may include one or more windows for coronary access and may include one or more commissure reinforcement members coupled thereto to provide support for the prosthetic valve component.

Abstract translation: 实施例涉及一种经导管瓣膜假体，其包括管状织物本体，附接到管状织物主体的第一端部的第一或流入管状支架，以及附接到管状织物本体的第二端部的第二或流出管状支架 。 假体阀部件设置在管状织物主体的中间部分内并且被固定到纵向延伸在管状织物主体的第一和第二端部之间。 中间部分没有支撑，使得第一和第二管状支架都不包围管状织物本体的中间部分。 中间部分可以包括用于冠状动脉通路的一个或多个窗口，并且可以包括联接到其上的一个或多个连合加强构件，以为假体瓣膜部件提供支撑。

公开(公告)号：US20140243880A1

公开(公告)日：2014-08-28

申请号：US13777141

申请日：2013-02-26

Applicant: MEDTRONIC, INC.

Inventor： Elizabeth Schotzko ,  Joel Racchini ,  Jeffrey Sandstrom

IPC: A61F2/01

CPC classification number: A61F2/013 ,  A61F2002/011 ,  A61F2210/009

Abstract: An embolic protection device includes a shaft, a first magnet fixedly coupled to a distal portion of the shaft, a second magnet slidingly coupled to the shaft proximal to the first magnet, and a filter including a distal portion coupled to the first magnet and a proximal portion coupled to the second magnet. The first and second magnets are magnetically attracted to each other such that in a radially compressed configuration of the filter, the second magnet is spaced from the first magnet a first distance, and in a radially expanded configuration of the filter, the second magnet slides towards the first magnet such that the second magnet is spaced a second distance from the first magnet, wherein the second distance is smaller than the first distance.

Abstract translation: 栓塞保护装置包括轴，固定地连接到轴的远端部分的第一磁体，与第一磁体接近的轴滑动地联接的第二磁体，以及包括耦合到第一磁体的远端部分的过滤器和近端 部分联接到第二磁体。 第一和第二磁体彼此磁吸引，使得在过滤器的径向压缩构造中，第二磁体与第一磁体间隔第一距离，并且在过滤器的径向扩展构型中，第二磁体向 所述第一磁体使得所述第二磁体与所述第一磁体隔开第二距离，其中所述第二距离小于所述第一距离。

公开(公告)号：US20220323148A1

公开(公告)日：2022-10-13

申请号：US17851984

申请日：2022-06-28

Applicant: Medtronic, Inc.

Inventor： Paul T. Rothstein ,  Roger D. Greeley ,  Jeffrey D. Sandstrom ,  Joel Racchini ,  James R. Keogh

IPC: A61B18/14 ,  A61B17/00 ,  A61B17/12 ,  A61B17/32

Abstract: The disclosure includes methods, systems and devices for severing and optionally removing at least a portion of heart valve leaflets. Leaflets can be partially removed or entirely removed or otherwise, the leaflets can be severed or splayed in such a way as to avoid coronary blockage, LVOT obstruction, or access challenges in procedures where a prosthetic valve is to be implanted within a previously implanted prosthetic valve. The disclosure also relate to numerous devices for and methods of disabling one or more valve ligating devices to provide an unobstructed valve opening so that a prosthetic heart valve can be implanted within the opening. The ligation device(s) is disabled either by removing the ligation device(s) or severing one leaflet so that ligated leaflets can be separated. In some embodiments, the ligation device(s) are severed to disable the ligation device(s).

公开(公告)号：US20210177593A1

公开(公告)日：2021-06-17

申请号：US17168903

申请日：2021-02-05

Applicant: Medtronic, Inc.

Inventor： Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

Abstract: A system for replacing a heart valve of a patient. The system includes a delivery device and a prosthetic heart valve. The system is configured to be transitionable between a loaded state, a partially deployed state and a deployed state. In the loaded state, the prosthetic heart valve engages a coupling structure and is compressively retained within a primary capsule, which constrains the prosthetic heart valve in a compressed arrangement. In the partially deployed state, the prosthetic heart valve engages the coupling structure and is compressively retained within a secondary capsule, which constrains the prosthetic heart valve to a partially deployed arrangement. The partially deployed arrangement is less compressed than the compressed arrangement and less expanded than a deployed arrangement. In the deployed state, the primary and secondary capsules are retracted from over the prosthetic heart valve, which expands to the deployed arrangement and is released from the coupling structure.

公开(公告)号：US10945840B2

公开(公告)日：2021-03-16

申请号：US16167676

申请日：2018-10-23

Applicant: Medtronic, Inc.

Inventor： Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24 ,  A61F2/95

Abstract: A system for replacing a heart valve of a patient. The system includes a delivery device and a prosthetic heart valve. The system is configured to be transitionable between a loaded state, a partially deployed state and a deployed state. In the loaded state, the prosthetic heart valve engages a coupling structure and is compressively retained within a primary capsule, which constrains the prosthetic heart valve in a compressed arrangement. In the partially deployed state, the prosthetic heart valve engages the coupling structure and is compressively retained within a secondary capsule, which constrains the prosthetic heart valve to a partially deployed arrangement. The partially deployed arrangement is less compressed than the compressed arrangement and less expanded than a deployed arrangement. In the deployed state, the primary and secondary capsules are retracted from over the prosthetic heart valve, which expands to the deployed arrangement and is released from the coupling structure.

公开(公告)号：US10555811B2

公开(公告)日：2020-02-11

申请号：US15405070

申请日：2017-01-12

Applicant: Medtronic, Inc.

Inventor： Joel Racchini ,  Jeffrey Sandstrom

IPC: A61F2/24 ,  A61M25/01

Abstract: A delivery device for percutaneously delivering a stented prosthetic heart valve includes a capsule assembly, a handle, and an outer stability shaft. The capsule assembly includes a capsule and a proximal shaft coupled to the capsule. The capsule includes an expanded configuration wherein the capsule has a first outer diameter, and a collapsed configuration wherein the capsule has a second outer diameter smaller than the first outer diameter. The outer stability shaft defines a lumen and is coupled to the handle and configured to receive the proximal shaft within the lumen of the outer stability shaft. The outer stability shaft has an inner diameter, wherein the first outer diameter of the capsule is greater than the inner diameter of the outer stability shaft and the second outer diameter of the capsule is smaller than the inner diameter of the outer stability shaft.

公开(公告)号：US20190053901A1

公开(公告)日：2019-02-21

申请号：US16167676

申请日：2018-10-23

Applicant: Medtronic, Inc.

Inventor： Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

Abstract: A system for replacing a heart valve of a patient. The system includes a delivery device and a prosthetic heart valve. The system is configured to be transitionable between a loaded state, a partially deployed state and a deployed state. In the loaded state, the prosthetic heart valve engages a coupling structure and is compressively retained within a primary capsule, which constrains the prosthetic heart valve in a compressed arrangement. In the partially deployed state, the prosthetic heart valve engages the coupling structure and is compressively retained within a secondary capsule, which constrains the prosthetic heart valve to a partially deployed arrangement. The partially deployed arrangement is less compressed than the compressed arrangement and less expanded than a deployed arrangement. In the deployed state, the primary and secondary capsules are retracted from over the prosthetic heart valve, which expands to the deployed arrangement and is released from the coupling structure.

公开(公告)号：US20170224480A1

公开(公告)日：2017-08-10

申请号：US15494923

申请日：2017-04-24

Applicant: Medtronic, Inc.

Inventor： Kshitija Garde ,  Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.

公开(公告)号：US09675451B2

公开(公告)日：2017-06-13

申请号：US14242347

申请日：2014-04-01

Applicant: Medtronic, Inc.

Inventor： Kshitija Garde ,  Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2220/005 ,  A61F2230/0013 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0069

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments. The segments may be orthogonal or oblique to the outer surface of the tubular stent.