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    Integrated valve assembly and method of delivering and deploying an integrated valve assembly
    2.
    发明授权
    Integrated valve assembly and method of delivering and deploying an integrated valve assembly 有权

    公开(公告)号：US11737869B2

    公开(公告)日：2023-08-29

    申请号：US17017382

    申请日：2020-09-10

    Applicant: Medtronic, Inc.

    Inventor： Paul Rothstein ,  Jeffrey Sandstrom ,  Geoffrey Orth

    IPC: A61F2/24 ,  A61F2/82

    CPC classification number: A61F2/2418 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2220/0008 ,  A61F2250/006

    Abstract: An integrated valve prosthesis includes an anchor stent, a tether component, and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the annulus of an aortic valve or the aorta. The valve component includes a valve frame and a prosthetic valve coupled to the valve frame, and is configured to be deployed within the anchor stent. The tether component includes a first end coupled to the anchor stent and a second end coupled to the valve frame. In the delivery configuration, the tether component extends in a first direction from the anchor stent to the valve component, and in the deployed configuration, the tether component extends in a second direction from the anchor stent to the valve component. The second direction is generally opposite the first direction. The tether component may set the location of the valve component relative to the anchor stent.

    POLYMERIC ENCLOSURE FOR IMPLANTABLE MEDICAL DEVICE
    3.
    发明申请
    POLYMERIC ENCLOSURE FOR IMPLANTABLE MEDICAL DEVICE 有权

    公开(公告)号：US20220273956A1

    公开(公告)日：2022-09-01

    申请号：US17649593

    申请日：2022-02-01

    Applicant: Medtronic, Inc.

    Inventor： Matthew D. Bonner ,  Pradipta K. Das ,  Allan E. Dienes ,  Jeffrey Sandstrom ,  Jeffrey S. Voss

    IPC: A61N1/375

    Abstract: An implantable medical device system is configured to generate signals and deliver the signals to a heart of a patient. The implantable medical device system includes electronic circuitry configured to deliver cardiac pacing, couplings for an implantable medical lead receptacle, at least some of the couplings electrically connected with the electronic circuitry, a polymeric enclosure having the electronic circuitry contained therein, the polymeric enclosure formed of polymeric material filled around the electronic circuitry and couplings and forming the implantable medical lead receptacle. The implantable medical device may include a first cavity filled with a first material and a second cavity filled with a second material, and the first material is different than the second material.

    Integrated valve assembly and method of delivering and deploying an integrated valve assembly
    4.
    发明授权
    Integrated valve assembly and method of delivering and deploying an integrated valve assembly 有权

    公开(公告)号：US10799343B2

    公开(公告)日：2020-10-13

    申请号：US16023475

    申请日：2018-06-29

    Applicant: Medtronic, Inc.

    Inventor： Paul Rothstein ,  Jeffrey Sandstrom ,  Geoffrey Orth

    IPC: A61F2/24 ,  A61F2/82

    Abstract: An integrated valve prosthesis includes an anchor stent, a tether component, and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the annulus of an aortic valve or the aorta. The valve component includes a valve frame and a prosthetic valve coupled to the valve frame, and is configured to be deployed within the anchor stent. The tether component includes a first end coupled to the anchor stent and a second end coupled to the valve frame. In the delivery configuration, the tether component extends in a first direction from the anchor stent to the valve component, and in the deployed configuration, the tether component extends in a second direction from the anchor stent to the valve component. The second direction is generally opposite the first direction. The tether component may set the location of the valve component relative to the anchor stent.

    Segmented transcatheter valve prosthesis having an unsupported valve segment
    5.
    发明授权
    Segmented transcatheter valve prosthesis having an unsupported valve segment 有权

    公开(公告)号：US10219896B2

    公开(公告)日：2019-03-05

    申请号：US15609106

    申请日：2017-05-31

    Applicant: Medtronic, Inc.

    Inventor： Jeffrey Sandstrom ,  Alaena Maiorano ,  Joel Racchini

    IPC: A61F2/24 ,  A61F2/07 ,  A61F2/82

    Abstract: Embodiments hereof relate to a transcatheter valve prosthesis including a tubular fabric body, a first or inflow tubular scaffold attached to a first end portion of the tubular fabric body, and a second or outflow tubular scaffold attached to a second end portion of the tubular fabric body. A prosthetic valve component is disposed within and secured to an intermediate portion of the tubular fabric body that longitudinally extends between the first and second end portions of the tubular fabric body. The intermediate portion is unsupported such that neither of the first and second tubular scaffolds surrounds the intermediate portion of the tubular fabric body. The intermediate portion may include one or more windows for coronary access and may include one or more commissure reinforcement members coupled thereto to provide support for the prosthetic valve component.

    INTEGRATED VALVE ASSEMBLY AND METHOD OF DELIVERING AND DEPLOYING AN INTEGRATED VALVE ASSEMBLY
    7.
    发明申请
    INTEGRATED VALVE ASSEMBLY AND METHOD OF DELIVERING AND DEPLOYING AN INTEGRATED VALVE ASSEMBLY 审中-公开
    集成阀组件及其输送和分配集成阀组件的方法

    公开(公告)号：US20160235525A1

    公开(公告)日：2016-08-18

    申请号：US15013341

    申请日：2016-02-02

    Applicant: Medtronic, Inc.

    Inventor： Paul Rothstein ,  Jeffrey Sandstrom ,  Geoffrey Orth

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2002/826 ,  A61F2002/828 ,  A61F2220/0008 ,  A61F2250/006

    Abstract: An integrated valve prosthesis includes an anchor stent, a tether component, and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the annulus of an aortic valve or the aorta. The valve component includes a valve frame and a prosthetic valve coupled to the valve frame, and is configured to be deployed within the anchor stent. The tether component includes a first end coupled to the anchor stent and a second end coupled to the valve frame. In the delivery configuration, the tether component extends in a first direction from the anchor stent to the valve component, and in the deployed configuration, the tether component extends in a second direction from the anchor stent to the valve component. The second direction is generally opposite the first direction. The tether component may set the location of the valve component relative to the anchor stent.

    Abstract translation: 整体式阀门假体包括锚固支架，系绳部件和阀部件。 锚固支架包括构造成部署在主动脉瓣或主动脉的环中的自膨胀管状框架构件。 阀部件包括阀框架和联接到阀框架的假体阀，并且构造成展开在锚固支架内。 系链部件包括联接到锚固支架的第一端和联接到阀框架的第二端。 在输送构造中，系链部件在锚定支架到阀部件的第一方向上延伸，并且在展开构造中，系链部件沿着第二方向从锚固支架延伸到阀部件。 第二方向通常与第一方向相反。 系链部件可以相对于锚固支架设置阀部件的位置。

    System and Method of Stepped Deployment of Prosthetic Heart Valve
    8.
    发明申请
    System and Method of Stepped Deployment of Prosthetic Heart Valve 审中-公开
    心脏瓣膜假手术的系统与方法

    公开(公告)号：US20150272731A1

    公开(公告)日：2015-10-01

    申请号：US14231879

    申请日：2014-04-01

    Applicant: MEDTRONIC, INC.

    Inventor： Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

    IPC: A61F2/24

    CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2002/9522

    Abstract: A system for replacing a heart valve of a patient. The system includes a delivery device and a prosthetic heart valve. The system is configured to be transitionable between a loaded state, a partially deployed state and a deployed state. In the loaded state, the prosthetic heart valve engages a coupling structure and is compressively retained within a primary capsule, which constrains the prosthetic heart valve in a compressed arrangement. In the partially deployed state, the prosthetic heart valve engages the coupling structure and is compressively retained within a secondary capsule, which constrains the prosthetic heart valve to a partially deployed arrangement. The partially deployed arrangement is less compressed than the compressed arrangement and less expanded than a deployed arrangement. In the deployed state, the primary and secondary capsules are retracted from over the prosthetic heart valve, which expands to the deployed arrangement and is released from the coupling structure.

    Abstract translation: 一种用于更换患者心脏瓣膜的系统。 该系统包括输送装置和假体心脏瓣膜。 该系统被配置为在加载状态，部署部署状态和部署状态之间可转换。 在负载状态下，假体心脏瓣膜接合联接结构并且被压缩地保持在主胶囊内，其以压缩的布置约束假体心脏瓣膜。 在部分展开的状态下，假体心脏瓣膜接合联接结构并且被压缩地保持在次级胶囊内，其将假体心脏瓣膜约束为部分展开的布置。 部分布置的布置比压缩布置压缩得更少，并且比部署的布置少。 在展开状态下，主胶囊和辅助胶囊从假体心脏瓣膜上方缩回，该心脏瓣膜膨胀到展开的装置并从联接结构释放。

    Anti-Paravalvular Leakage Component for a Transcatheter Valve Prosthesis
    9.
    发明申请
    Anti-Paravalvular Leakage Component for a Transcatheter Valve Prosthesis 有权
    用于经导管瓣假体的抗瓣膜渗漏组件

    公开(公告)号：US20140277419A1

    公开(公告)日：2014-09-18

    申请号：US13795066

    申请日：2013-03-12

    Applicant: MEDTRONIC, INC.

    Inventor： Kshitija Garde ,  Philip Haarstad ,  Igor Kovalsky ,  Stephen Nash ,  Michael Krivoruchko ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Jeffrey Sandstrom ,  Padraig Savage ,  Adam Shipley ,  William Steinberg

    IPC: A61F2/24

    CPC classification number: A61F2/2445 ,  A61F2/2403 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2250/0069

    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the stent which includes a plurality of self-expanding struts and an annular sealing membrane. Each strut has a first end coupled to a distal end of the stent and a second end not coupled to the stent. Each anti-paravalvular leakage component is moveable between a compressed configuration and a deployed configuration. In the compressed configuration, each strut extends distally away from the distal end of the stent. In the deployed configuration, each strut extends proximally away from the distal end of the stent. In an embodiment hereof, the deployed strut has a C-shape and is twisted such that the C-shape lies in a plane substantially along or tangential with the outer surface of the stent. In another embodiment hereof, the deployed strut is rolled-up and extends radially away from the outer surface of the stent.

    Abstract translation: 经导管瓣膜假体包括可扩张的管状支架，支架内的假体瓣膜，以及耦合到环绕支架并包围多个自膨胀支柱和环形密封膜的抗瓣膜泄漏部件。 每个支柱具有联接到支架的远端的第一端和未联接到支架的第二端。 每个反paravalvular泄漏组件可在压缩配置和部署配置之间移动。 在压缩构型中，每个支柱远离支架远端延伸。 在展开的构造中，每个支柱向近端延伸远离支架的远端。 在本发明的一个实施例中，所展开的支柱具有C形并且被扭曲，使得C形位于与支架的外表面基本上沿或相切的平面中。 在本发明的另一个实施例中，部署的支柱被卷起并且从支架的外表面径向延伸。

    SYSTEM AND METHOD OF STEPPED DEPLOYMENT OF PROSTHETIC HEART VALVE
    10.
    发明公开
    SYSTEM AND METHOD OF STEPPED DEPLOYMENT OF PROSTHETIC HEART VALVE 审中-公开

    公开(公告)号：US20240261096A1

    公开(公告)日：2024-08-08

    申请号：US18609498

    申请日：2024-03-19

    Applicant: Medtronic, Inc.

    Inventor： Joel Racchini ,  Paul Rothstein ,  Jeffrey Sandstrom

    IPC: A61F2/24 ,  A61F2/95

    CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/9522 ,  A61F2/9524

    Abstract: A system for replacing a heart valve of a patient. The system includes a delivery device and a prosthetic heart valve. The system is configured to be transitionable between a loaded state, a partially deployed state and a deployed state. In the loaded state, the prosthetic heart valve engages a coupling structure and is compressively retained within a primary capsule, which constrains the prosthetic heart valve in a compressed arrangement. In the partially deployed state, the prosthetic heart valve engages the coupling structure and is compressively retained within a secondary capsule, which constrains the prosthetic heart valve to a partially deployed arrangement. The partially deployed arrangement is less compressed than the compressed arrangement and less expanded than a deployed arrangement. In the deployed state, the primary and secondary capsules are retracted from over the prosthetic heart valve, which expands to the deployed arrangement and is released from the coupling structure.

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