公开(公告)号：US20140249605A1

公开(公告)日：2014-09-04

申请号：US14276516

申请日：2014-05-13

Applicant: Medtronic, Inc.

Inventor： Kenneth T. Heruth ,  Keith A. Miesel

IPC: A61N1/36

CPC classification number: A61N1/36139 ,  A61B3/113 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/4815 ,  A61B5/6826 ,  A61B5/686 ,  A61M5/14276 ,  A61M5/1723 ,  A61N1/36071 ,  A61N1/36078 ,  A61N1/36135 ,  A61N1/36514 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36557 ,  A61N1/3702 ,  A61N1/37247

Abstract: At least one of a medical device, such as an implantable medical device, and a programming device determines values for one or more metrics that indicate the quality of a patient's sleep. Sleep efficiency, sleep latency, and time spent in deeper sleep states are example sleep quality metrics for which values may be determined. In some embodiments, determined sleep quality metric values are associated with a current therapy parameter set. In some embodiments, a programming device presents sleep quality information to a user based on determined sleep quality metric values. A clinician, for example, may use the sleep quality information presented by the programming device to evaluate the effectiveness of therapy delivered to the patient by the medical device, to adjust the therapy delivered by the medical device, or to prescribe a therapy not delivered by the medical device in order to improve the quality of the patient's sleep.

Abstract translation: 诸如可植入医疗设备的医疗设备和编程设备中的至少一个确定了指示患者睡眠质量的一个或多个度量的值。 睡眠效率，睡眠延迟和在更深的睡眠状态中花费的时间是可以确定值的示例性睡眠质量度量。 在一些实施例中，确定的睡眠质量度量值与当前治疗参数组相关联。 在一些实施例中，编程设备基于确定的睡眠质量度量值向用户呈现睡眠质量信息。 例如，临床医生可以使用编程设备呈现的睡眠质量信息来评估由医疗设备递送给患者的治疗的有效性，以调整由医疗设备递送的治疗，或者开出不由 医疗器械为了提高病人的睡眠质量。

公开(公告)号：US10512427B2

公开(公告)日：2019-12-24

申请号：US13764911

申请日：2013-02-12

Applicant: Medtronic, Inc.

Inventor： Richard T. Stone ,  Keith A. Miesel

IPC: A61B7/00 ,  A61B5/20 ,  A61B5/11 ,  A61B5/00 ,  A61N1/36 ,  A61N1/05

Abstract: A bladder fullness level of a patient may be determined based on a frequency of mechanical oscillations of the bladder of the patient. The bladder may mechanically oscillate in response to the occurrence of non-micturition contractions of the bladder of the patient, which are contractions not associated with urine release. The frequency at which the bladder oscillates, e.g., following a non-micturition contraction, may have a correlation to the bladder fullness level. In some examples, a medical device may be configured to control the delivery of electrical stimulation therapy to the patient based on the oscillation frequency of the bladder. In addition, or instead to controlling therapy based on the oscillation frequency of the bladder, a notification, such as a patient or patient caretaker notification, may be generated (e.g., automatically by a processor of a device) based on the oscillation frequency of the bladder.

公开(公告)号：US10357620B2

公开(公告)日：2019-07-23

申请号：US14860198

申请日：2015-09-21

Applicant: Medtronic, Inc.

Inventor： Keith A. Miesel

IPC: A61M5/50 ,  A61M5/168 ,  A61M5/142 ,  A61M27/00 ,  A61M5/172

Abstract: A method for determining the status of a catheter of an implanted infusion system, where the catheter is intended to deliver a fluid composition to CSF of a patient, includes monitoring catheter pressure, developing a pressure modulation profile based on the monitored pressure, and comparing the developed pressure modulation profile to a predetermined pressure profile. The predetermined pressure profile may be a profile of cerebrospinal fluid or a bolus infusion or withdrawal profile for the catheter. A determination of catheter status, such as properly functioning, occluded or leaky, can be made based on the comparison.

公开(公告)号：US20170340814A1

公开(公告)日：2017-11-30

申请号：US15681957

申请日：2017-08-21

Applicant: Medtronic, Inc.

Inventor： Keith A. Miesel ,  James M. Haase ,  Chris J. Paidosh ,  Darren A. Janzig ,  Timothy J. Denison

IPC: A61M5/142 ,  G01L19/08 ,  G01L9/00 ,  A61M39/02 ,  G01L15/00 ,  G01L19/14 ,  G01L19/00

CPC classification number: A61M5/14276 ,  A61M39/0208 ,  A61M2205/3317 ,  A61M2205/3331 ,  G01L9/0072 ,  G01L15/00 ,  G01L19/0023 ,  G01L19/0069 ,  G01L19/086 ,  G01L19/143 ,  G01L19/148 ,  G01L19/149

Abstract: The disclosure is directed to a pressure sensor of an implantable medical device. The pressure sensor may utilize detect fluid pressure based on a changing capacitance between two capacitive elements. The pressure sensor may define at least a portion of a fluid enclosure of the IMD. In one example, the pressure sensor has a self-aligning housing shape that occludes an opening in the pump bulkhead of the IMD. An operative surface of the pressure and the portion of the fluid enclosure may be formed of a corrosion resistant and/or biocompatible material. A first capacitive element of the pressure sensor may be a metal alloy diaphragm that deflects in response to external fluid pressure. A second capacitive element of the pressure sensor may be a metal coating on a rigid insulator sealed from the fluid by the diaphragm and a housing of the sensor.

公开(公告)号：US09623248B2

公开(公告)日：2017-04-18

申请号：US14961344

申请日：2015-12-07

Applicant: Medtronic, Inc.

Inventor： Kenneth T. Heruth ,  Keith A. Miesel

IPC: A61B5/00 ,  A61B5/04 ,  A61N1/36 ,  A61B5/0476 ,  A61B5/11 ,  A61M5/142 ,  A61M5/172 ,  A61N1/372 ,  A61B3/113 ,  A61B5/01 ,  A61B5/0402 ,  A61N1/37 ,  A61N1/365

CPC classification number: A61N1/36139 ,  A61B3/113 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/4815 ,  A61B5/6826 ,  A61B5/686 ,  A61M5/14276 ,  A61M5/1723 ,  A61N1/36071 ,  A61N1/36078 ,  A61N1/36135 ,  A61N1/36514 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36557 ,  A61N1/3702 ,  A61N1/37247

Abstract: At least one of a medical device, such as an implantable medical device, and a programming device determines values for one or more metrics that indicate the quality of a patient's sleep. Sleep efficiency, sleep latency, and time spent in deeper sleep states are example sleep quality metrics for which values may be determined. In some embodiments, determined sleep quality metric values are associated with a current therapy parameter set. In some embodiments, a programming device presents sleep quality information to a user based on determined sleep quality metric values. A clinician, for example, may use the sleep quality information presented by the programming device to evaluate the effectiveness of therapy delivered to the patient by the medical device, to adjust the therapy delivered by the medical device, or to prescribe a therapy not delivered by the medical device in order to improve the quality of the patient's sleep.

公开(公告)号：US20160158552A1

公开(公告)日：2016-06-09

申请号：US14961344

申请日：2015-12-07

Applicant: Medtronic, Inc.

Inventor： Kenneth T. Heruth ,  Keith A. Miesel

IPC: A61N1/36 ,  A61N1/372 ,  A61B5/00

CPC classification number: A61N1/36139 ,  A61B3/113 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/4815 ,  A61B5/6826 ,  A61B5/686 ,  A61M5/14276 ,  A61M5/1723 ,  A61N1/36071 ,  A61N1/36078 ,  A61N1/36135 ,  A61N1/36514 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36557 ,  A61N1/3702 ,  A61N1/37247

Abstract: At least one of a medical device, such as an implantable medical device, and a programming device determines values for one or more metrics that indicate the quality of a patient's sleep. Sleep efficiency, sleep latency, and time spent in deeper sleep states are example sleep quality metrics for which values may be determined. In some embodiments, determined sleep quality metric values are associated with a current therapy parameter set. In some embodiments, a programming device presents sleep quality information to a user based on determined sleep quality metric values values. A clinician, for example, may use the sleep quality information presented by the programming device to evaluate the effectiveness of therapy delivered to the patient by the medical device, to adjust the therapy delivered by the medical device, or to prescribe a therapy not delivered by the medical device in order to improve the quality of the patient's sleep.

Abstract translation: 诸如可植入医疗设备的医疗设备和编程设备中的至少一个确定了指示患者睡眠质量的一个或多个度量的值。 睡眠效率，睡眠延迟和在更深的睡眠状态中花费的时间是可以确定值的示例性睡眠质量度量。 在一些实施例中，确定的睡眠质量度量值与当前治疗参数组相关联。 在一些实施例中，编程设备基于确定的睡眠质量度量值值向用户呈现睡眠质量信息。 例如，临床医生可以使用编程设备呈现的睡眠质量信息来评估由医疗设备递送给患者的治疗的有效性，以调整由医疗设备递送的治疗，或者开出不由 医疗器械为了提高病人的睡眠质量。

公开(公告)号：US20200001007A1

公开(公告)日：2020-01-02

申请号：US16565013

申请日：2019-09-09

Applicant: Medtronic, Inc.

Inventor： Keith A. Miesel ,  James M. Haase ,  Chris J. Paidosh ,  Darren A. Janzig ,  Timothy J. Denison

IPC: A61M5/142 ,  A61M39/02 ,  G01L9/00 ,  G01L15/00 ,  G01L19/00 ,  G01L19/08 ,  G01L19/14

Abstract: The disclosure is directed to a pressure sensor of an implantable medical device. The pressure sensor may utilize detect fluid pressure based on a changing capacitance between two capacitive elements. The pressure sensor may define at least a portion of a fluid enclosure of the IMD. In one example, the pressure sensor has a self-aligning housing shape that occludes an opening in the pump bulkhead of the IMD. An operative surface of the pressure and the portion of the fluid enclosure may be formed of a corrosion resistant and/or biocompatible material. A first capacitive element of the pressure sensor may be a metal alloy diaphragm that deflects in response to external fluid pressure. A second capacitive element of the pressure sensor may be a metal coating on a rigid insulator sealed from the fluid by the diaphragm and a housing of the sensor.

公开(公告)号：US10251595B2

公开(公告)日：2019-04-09

申请号：US15439152

申请日：2017-02-22

Applicant: Medtronic, Inc.

Inventor： Kenneth T. Heruth ,  Keith A. Miesel ,  Gregory F. Molnar

IPC: A61N1/37 ,  A61B5/00 ,  A61B5/0488 ,  A61B5/103 ,  A61N1/36 ,  A61B5/03 ,  A61B5/11 ,  A61M5/172 ,  G06F19/00

Abstract: A medical device delivers a therapy to a patient. The medical device or another device may periodically determine an activity level or gait parameter of the patient, and associate each determined level or parameter with a current therapy parameter set. A value of at least one activity metric is determined for each of a plurality of therapy parameter sets based on the activity levels or parameters associated with that therapy parameter set. Whether the patient is currently experiencing or anticipated to experience gait freeze caused by their neurological disorder, such as Parkinson's disease, may also be determined. Gait freeze events may be associated with current therapy parameters and used to determine activity metric values. In some examples, the activity metric associated with certain therapy parameters may be presented to a user.

公开(公告)号：US20160367803A1

公开(公告)日：2016-12-22

申请号：US15256369

申请日：2016-09-02

Applicant: Medtronic, Inc.

Inventor： Xuan K. Wei ,  Eric H. Bonde ,  Keith A. Miesel ,  Mark S. Lent ,  Gregory F. Molnar

IPC: A61N1/36 ,  A61N1/372 ,  A61N1/05

CPC classification number: A61N1/36007 ,  A61N1/0514 ,  A61N1/0551 ,  A61N1/36128 ,  A61N1/36135 ,  A61N1/37235 ,  A61N1/37252

Abstract: Techniques for managing urinary or fecal incontinence include delivering a first type of therapy to generate a first physiological response and, upon detecting a trigger event, delivering a second type of therapy to generate a second physiological response. The first type of therapy can be delivered on a substantially regular basis, while the second type of therapy is delivered as needed to provide an additional boost of therapy. The trigger event for activating the delivery of the second type of therapy may include input from a sensor that indicates a bladder condition, patient activity level or patient posture, or patient input. In some examples, the therapy is stimulation therapy.

Abstract translation: 用于管理尿失禁或大便失禁的技术包括递送第一类型的治疗以产生第一生理反应，并且在检测到触发事件时，递送第二类型的治疗以产生第二生理反应。 第一种类型的治疗可以基本上定期地递送，而第二种类型的治疗根据需要被递送以提供额外的治疗效果。 用于激活第二类治疗的递送的触发事件可以包括来自传感器的输入，其指示膀胱状况，患者活动水平或患者姿势或患者输入。 在一些例子中，治疗是刺激疗法。

公开(公告)号：US20160263382A1

公开(公告)日：2016-09-15

申请号：US15160455

申请日：2016-05-20

Applicant: Medtronic, Inc.

Inventor： Kenneth T. Heruth ,  Keith A. Miesel

IPC: A61N1/36 ,  A61N1/37 ,  A61B5/00 ,  A61B3/113 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/0476 ,  A61N1/365 ,  A61N1/372

CPC classification number: A61N1/36139 ,  A61B3/113 ,  A61B5/01 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/4815 ,  A61B5/6826 ,  A61B5/686 ,  A61M5/14276 ,  A61M5/1723 ,  A61N1/36071 ,  A61N1/36078 ,  A61N1/36135 ,  A61N1/36514 ,  A61N1/36521 ,  A61N1/36542 ,  A61N1/36557 ,  A61N1/3702 ,  A61N1/37247

Abstract: At least one of a medical device, such as an implantable medical device, a monitor, and a computing device determines values for one or more metrics that indicate the quality of a patient's sleep. Sleep efficiency, sleep latency, and time spent in deeper sleep states are example sleep quality metrics for which values may be determined. In some embodiments, determined sleep quality metric values are associated with a current therapy parameter set. In some embodiments, a programming device presents sleep quality information to a user based on determined sleep quality metric values. A clinician, for example, may use the sleep quality information presented by the programming device to evaluate the effectiveness of therapy delivered to the patient by the medical device, to adjust the therapy delivered by the medical device, or to prescribe a therapy not delivered by the medical device in order to improve the quality of the patient's sleep.

Abstract translation: 诸如可植入医疗设备，监视器和计算设备的医疗设备中的至少一个确定了指示患者睡眠质量的一个或多个度量的值。 睡眠效率，睡眠延迟和在更深的睡眠状态中花费的时间是可以确定值的示例性睡眠质量度量。 在一些实施例中，确定的睡眠质量度量值与当前治疗参数组相关联。 在一些实施例中，编程设备基于确定的睡眠质量度量值向用户呈现睡眠质量信息。 例如，临床医生可以使用编程设备呈现的睡眠质量信息来评估由医疗设备递送给患者的治疗的有效性，以调整由医疗设备递送的治疗，或者开出不由 医疗器械为了提高病人的睡眠质量。