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公开(公告)号：US11786754B2
公开(公告)日：2023-10-17
申请号：US17567544
申请日：2022-01-03
发明人： Gerrit Townsend Zwart , Mark R. Jones , Miles S. Wagner , James Cooley , Eros Pedroni , Robert Silva
IPC分类号： A61N5/10
CPC分类号： A61N5/1036 , A61N5/1043 , A61N5/1044 , A61N5/1045 , A61N5/1047 , A61N5/1071 , A61N5/1077 , A61N5/1081 , A61N2005/1087 , A61N2005/1095
摘要： An example particle therapy system includes a particle accelerator to output a particle beam having a spot size; a scanning system for the particle accelerator to scan the particle beam in two dimensions across at least part of a treatment area of an irradiation target; and an adaptive aperture between the scanning system and the irradiation target. The adaptive aperture includes structures that are movable relative to the irradiation target to approximate a shape to trim part of the treatment area. The part of the treatment area has a size that is based on an area of the spot size.
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公开(公告)号：US20220272827A1
公开(公告)日：2022-08-25
申请号：US17675142
申请日：2022-02-18
发明人： Yan Zhang , Gerrit Townsend Zwart , James Cooley , Mark R. Jones , Honghai Song , Yan Liu , Xunjie Yu
摘要： An example particle therapy system includes a gantry having a beamline structure configured to direct a particle beam that is monoenergetic from an output of a particle accelerator towards an irradiation target, where the beamline structure includes magnetic bending elements to bend the particle beam along a length of the beamline structure; and an energy degrader downstream of the beamline structure relative to the particle accelerator, where the energy degrader is configured and controllable to change an energy of the particle beam prior to at least part of the particle beam reaching the irradiation target.
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公开(公告)号：US20210274635A1
公开(公告)日：2021-09-02
申请号：US17174986
申请日：2021-02-12
发明人： James Cooley , Gerrit Townsend Zwart , Stanley J. Rosenthal , Mark R. Jones , Lionel G. Bouchet , Robert Cessac , Joseph Jachinowski
摘要： An example method includes: receiving, from a treatment planning process, information that is based on a dose distribution for an irradiation target; and performing at least one of the following operations: moving structures to trim spots of a particle beam so that the spots of the particle beam approximate pre-trimmed spots for which characteristics are obtained based on the information received; moving structures to produce a trimming curve for a layer of an irradiation target based on a specification of a trimming curve for the layer included in the information received; moving structures to produce a single trimming curve for all radiation fields of an irradiation target based on specifications of the single trimming curve included in the information received; or moving structures based on configuration information for the structures in the information received.
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公开(公告)号：US10786689B2
公开(公告)日：2020-09-29
申请号：US14937048
申请日：2015-11-10
发明人： Gerrit Townsend Zwart , Mark R. Jones , Miles S. Wagner , James Cooley , Eros Pedroni , Robert Silva
IPC分类号： A61N5/10
摘要： An example particle therapy system includes a particle accelerator to output a particle beam having a spot size; a scanning system for the particle accelerator to scan the particle beam in two dimensions across at least part of a treatment area of an irradiation target; and an adaptive aperture between the scanning system and the irradiation target. The adaptive aperture includes structures that are movable relative to the irradiation target to approximate a shape to trim part of the treatment area. The part of the treatment area has a size that is based on an area of the spot size.
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公开(公告)号：US10456591B2
公开(公告)日：2019-10-29
申请号：US15796237
申请日：2017-10-27
发明人： Gerrit Townsend Zwart , James Cooley , Ken Yoshiki Franzen , Mark R. Jones , Tao Li , Michael Busky
摘要： An example particle therapy system includes: a synchrocyclotron to output a particle beam; a magnet to affect a direction of the particle beam to scan the particle beam across at least part of an irradiation target; scattering material that is configurable to change a spot size of the particle beam, where the scattering material is down-beam of the magnet relative to the synchrocyclotron; and a degrader to change an energy of the beam prior to output of the particle beam to the irradiation target, where the degrader is down-beam of the scattering material relative to the synchrocyclotron.
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公开(公告)号：US20180236268A1
公开(公告)日：2018-08-23
申请号：US15441170
申请日：2017-02-23
IPC分类号： A61N5/10
CPC分类号： A61N5/1067 , A61N5/1043 , A61N5/1045 , A61N5/1049 , A61N5/1065 , A61N5/1069 , A61N5/107 , A61N5/1081 , A61N2005/1087 , A61N2005/1095
摘要： An example particle therapy system includes a particle beam output device to direct output of a particle beam; a treatment couch to support a patient containing an irradiation target, with the treatment couch being configured for movement; a movable device on which the particle beam output device is mounted for movement relative to the treatment couch; and a control system to provide automated control of at least one of the movable device or the treatment couch to position at least one of the particle beam or the irradiation target for treatment of the irradiation target with the particle beam and, following the treatment of the irradiation target with the particle beam, to provide automated control of at least one of the movable device or the treatment couch to reposition at least one of the particle beam or the irradiation target for additional treatment of the irradiation target with the particle beam.
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公开(公告)号：US20170182338A1
公开(公告)日：2017-06-29
申请号：US15399250
申请日：2017-01-05
摘要： An example particle therapy system may include: a synchrocyclotron to produce a particle beam; a scanner to move the particle beam in one or more dimensions relative to an irradiation target; and an energy degrader that is between the scanner and the irradiation target. The energy degrader may include multiple plates that are movable relative to a path of the particle beam, with the multiple plates each being controllable to move while in the path of the particle beam and during movement of the particle beam. An aperture may be between the energy degrader and the irradiation target. The aperture being may be to trim the particle beam prior to the particle beam reaching the irradiation target.
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公开(公告)号：US09622335B2
公开(公告)日：2017-04-11
申请号：US14039652
申请日：2013-09-27
CPC分类号： H05H13/02 , A61N5/1077 , H05H7/04 , H05H7/10 , H05H2007/046
摘要： An example particle accelerator includes the following: a voltage source to provide a radio frequency (RF) voltage to a cavity to accelerate particles from a plasma column, where the cavity has a magnetic field causing particles accelerated from the plasma column to move orbitally within the cavity; an extraction channel to receive the particles accelerated from the plasma column and to output the received particles from the cavity; and a regenerator to provide a magnetic field bump within the cavity to thereby change successive orbits of the particles accelerated from the plasma column so that, eventually, particles output to the extraction channel. The magnetic field is at least 6 Tesla and the magnetic field bump is at most 2 Tesla.
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公开(公告)号：US09301384B2
公开(公告)日：2016-03-29
申请号：US14039342
申请日：2013-09-27
发明人： Gerrit Townsend Zwart , Kenneth P. Gall , Jan Van der Laan , Stanley Rosenthal , Michael Busky , Charles D O'Neal, III , Ken Yoshiki Franzen
CPC分类号： H05H7/10 , A61N5/1077 , A61N2005/1095 , H05H7/04 , H05H13/02 , H05H2007/004
摘要： An example particle accelerator includes a coil to provide a magnetic field to a cavity; a particle source to provide a plasma column to the cavity; a voltage source to provide a radio frequency (RF) voltage to the cavity to accelerate particles from the plasma column, where the magnetic field causes particles accelerated from the plasma column to move orbitally within the cavity; an enclosure containing an extraction channel to receive the particles accelerated from the plasma column and to output the received particles from the cavity; and a structure arranged proximate to the extraction channel to change an energy level of the received particles.
摘要翻译： 示例性粒子加速器包括向空腔提供磁场的线圈; 用于向空腔提供等离子体柱的粒子源; 电压源，以向空腔提供射频（RF）电压以加速来自等离子体柱的粒子，其中磁场引起从等离子体柱加速的粒子在空腔内轨道移动; 包含提取通道的外壳，用于接收从等离子体柱加速的颗粒并从腔体输出接收的颗粒; 以及靠近提取通道设置的结构，以改变所接收的颗粒的能量水平。
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公开(公告)号：US20140062344A1
公开(公告)日：2014-03-06
申请号：US14075261
申请日：2013-11-08
IPC分类号： H05H13/02
CPC分类号： H05H13/02
摘要： A synchrocyclotron includes magnetic structures to provide a magnetic field to a cavity, a particle source to provide a plasma column to the cavity, where the particle source has a housing to hold the plasma column, and where the housing is interrupted at an acceleration region to expose the plasma column, and a voltage source to provide a radio frequency (RF) voltage to the cavity to accelerate particles from the plasma column at the acceleration region.
摘要翻译： 同步回旋加速器包括向空腔提供磁场的磁性结构，为空腔提供等离子体柱的颗粒源，其中颗粒源具有用于保持等离子体柱的壳体，并且其中壳体在加速区域被中断 暴露等离子体柱和电压源以向空腔提供射频（RF）电压以在加速区域加速来自等离子体柱的颗粒。
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