摘要:
Methods of predicting datacenter performance to improve provisioning are described. In an embodiment, a resource manager element receives a request from a tenant which describes an application that the tenant wants executed by a multi-resource, multi-tenant datacenter. The request that has been received is mapped to a set of different candidate resource combinations within the datacenter, where each candidate resource combination can be used to execute the application in a manner which satisfies a high level constraint specified within the request. This mapping may, for example, be performed using a combination of benchmarking and an analytical model. In some examples, each resource combination may comprise a number of virtual machines and a bandwidth between those machines. Data relating to at least a subset (and in some examples, two or more) of the candidate resource combinations is then presented to the tenant.
摘要:
Sampling rules for information dissemination are described which may be applied in a system containing a number of nodes arranged into groups. A target address is selected using one of two methods: selection of an address from the entire address space of the system and selection of an address from a part of the address space which corresponds to set of groups of nodes. The set of groups of nodes is updated when information is successfully disseminated to a node at a target address selected using the first of the two methods. Rules to determine which of the two methods are used for any particular selection operation are also described.
摘要:
An end-host based network management system and methods are described. The methods are performed independently at each end-host within the network based on data on local flows which is shared between end-hosts. In an embodiment, an end-host shares data on constrained local flows with other end-hosts and receives such data from other end-hosts. Based on this data, the end-host determines which flows from other nodes are competing for a shared resource with a constrained local flow and allocates the capacity of the shared resource between all the competing flows. This allocation is then enforced for the local flow by the end-host. Other end-hosts with competing flows perform similar methods and through an iterative process the contention for the shared resource is resolved and the utilization of the shared resource is optimized.
摘要:
Compositions comprising LSF compositions and treatment regiments comprising administration of LSF containing compositions are disclosed. Compositions and/or regiments may optionally include the administration of vitamins, minerals, and anti-oxidants. Methods for using these compositions and treatment regimens for treating subjects for diseases, including diseases associated with inflammation and/or oxidative stress, are provided. Various methods for use of the LSF compositions for inhibition of histone deacetylases (HDACs) in various cells, tissues, and/or conditions are also provided.
摘要:
Compositions comprising hydroxytyrosol-containing formulations and treatment regiments comprising hydroxytyrosol and/or oleuropein and chemotherapeutic agents are disclosed. Compositions and/or regiments may optionally include the administration of vitamins, minerals, and anti-oxidants. Methods for using these compositions and treatment regimens for treating subjects for diseases, such as a malignancy, and for inducing or enhancing angiogenesis, treating or preventing oxidative stress, for treating or preventing high glucose-induced dysfunction, treating or preventing chemotherapy-induced dysfunction, and for improving cell viability are provided. Various methods for use of the hydroxytyrosol compositions for inhibition of lysine specific demethylase 1 (LSD1) in various cancers are also provided.
摘要:
A decentralized relaying algorithm for mobile devices is described. In an embodiment, a mobile device acts as a relay within a network of mobile devices and on contact with a source device downloads messages from the source according to a locally stored relaying probability for each channel of information within the network. These messages are subsequently downloaded to another device which is the end user of the message. Where the relay does not download the message from the source as a result of the decision made based on the relaying probability, a virtual message is downloaded which comprises metadata only and not the payload of the message. The relay updates the stored relaying probabilities for each channel based on locally observable information which includes feedback received from mobile devices to which the relay has downloaded messages. The feedback identifies unique paths for the payload of messages through the network.
摘要:
Compositions comprising hydroxytyrosol-containing formulations and treatment regiments comprising hydroxytyrosol and/or oleuropein and chemotherapeutic agents are disclosed. Compositions and/or regiments may optionally include the administration of vitamins, minerals, and anti-oxidants. Methods for using these compositions and treatment regimens for treating subjects for diseases, such as a malignancy, and for inducing or enhancing angiogenesis, treating or preventing oxidative stress, for treating or preventing high glucose-induced dysfunction, treating or preventing chemotherapy-induced dysfunction, and for improving cell viability are provided. Various methods for use of the hydroxytyrosol compositions for inhibition of lysine specific demethylase 1 (LSD1) in various cancers are also provided.
摘要:
Resource optimization for online services is described. In one example, objects (such as mailboxes or other data associated with an online service) are assigned to network elements (such as servers) by inferring a relationship graph from log data relating to usage of the online service. The graph has a node for each object, and connections between each pair of objects having data items in common. Each connection has a weight relating to the number of common data items. The graph is partitioned into a set of clusters, such that each cluster has nodes joined by connections with a high weight relative to the weight of connections between nodes in different clusters. The objects are then distributed to the network elements such that objects corresponding to nodes in the same cluster are located on the same network element.
摘要:
An end-host based network management system and methods are described. The methods are performed independently at each end-host within the network based on data on local flows which is shared between end-hosts. In an embodiment, an end-host shares data on constrained local flows with other end-hosts and receives such data from other end-hosts. Based on this data, the end-host determines which flows from other nodes are competing for a shared resource with a constrained local flow and allocates the capacity of the shared resource between all the competing flows. This allocation is then enforced for the local flow by the end-host. Other end-hosts with competing flows perform similar methods and through an iterative process the contention for the shared resource is resolved and the utilization of the shared resource is optimized.
摘要:
Methods of predicting datacenter performance to improve provisioning are described. In an embodiment, a resource manager element receives a request from a tenant which describes an application that the tenant wants executed by a multi-resource, multi-tenant datacenter. The request that has been received is mapped to a set of different candidate resource combinations within the datacenter, where each candidate resource combination can be used to execute the application in a manner which satisfies a high level constraint specified within the request. This mapping may, for example, be performed using a combination of benchmarking and an analytical model. In some examples, each resource combination may comprise a number of virtual machines and a bandwidth between those machines. Data relating to at least a subset (and in some examples, two or more) of the candidate resource combinations is then presented to the tenant.