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公开(公告)号：US11109938B2
公开(公告)日：2021-09-07
申请号：US16175962
申请日：2018-10-31
Applicant: Novartis AG
Inventor： Jochen Horn , Alireza Mirsepassi , Chenguang Diao , Mark Harrison Farley , Ronald T. Smith
Abstract: Multi-fiber laser probes utilize relative motion of fibers and other laser probe elements to preserve small-gauge compatibility while providing for multi-spot beam deliver, or to provide for the selectively delivery of single-spot or multi-spot beam patterns. An example probe includes fibers having distal ends that are movable as a group onto a distal ramp element affixed to a distal end of a cannula, so that the distal ends of the fibers can be moved between a retracted position, in which the distal ends of the fibers are within the cannula or ramp element, and an extended position, in which distal ends of the fibers are guided by grooves or channels of the ramp so as to extend at least partially through external openings in the distal end of the laser probe and so as to be pointed angularly away from a longitudinal axis of the cannula.
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公开(公告)号：US20190216571A1
公开(公告)日：2019-07-18
申请号：US16365182
申请日：2019-03-26
Applicant: Novartis AG
Inventor： Alireza Mirsepassi , Ronald T. Smith , Michael J. Papac , Chenguang Diao
CPC classification number: A61B90/30 , A61B1/00096 , A61B1/0011 , A61B1/07 , A61B17/00 , A61B90/36 , A61B2017/00526 , A61B2090/306 , A61F9/007 , G02B5/021 , G02B5/0242 , G02B5/0247 , G02B6/0008 , G02B6/241 , G02B6/262
Abstract: A process of making a diverging-light fiber optics illumination delivery system includes providing a micro-post comprising a glass-ceramic light-scattering element that includes at least one of a ceramic, a glass ceramic, an immiscible glass, a porous glass, opal glass, amorphous glass, an aerated glass, and a nanostructured glass; and fusion-splicing the glass-ceramic micro-post to the optical fiber by pulling an arc between electrodes across a gap formed by the optical fiber and the glass-ceramic micro-post; maintaining the arc for a time sufficiently long to make facing surfaces of the optical fiber and the micro-post one of malleable and molten; and pushing and thereby fusing together the facing surfaces of the optical fiber and the micro-post. Some embodiments can include fusing the glass-ceramic micro-post to the optical fiber by applying a laser beam to heat up at least one of the facing surfaces of the optical fiber and the glass-ceramic micro-post.
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公开(公告)号：US20170119491A1
公开(公告)日：2017-05-04
申请号：US15073878
申请日：2016-03-18
Applicant: Novartis AG
Inventor： Alireza Mirsepassi , Michael James Papac , Barry L. Wheatley , Chenguang Diao
CPC classification number: A61B90/30 , A61B1/07 , A61B1/32 , A61B2090/306 , A61F9/007
Abstract: An ophthalmic cannula assembly may include a cannula having an outer cannula surface and an inner cylindrical bore. A hub adjoining a proximal end of the cannula may define a maximum outer hub diameter that is greater than an outer diameter of the cannula. An optical fiber may be attached to the outer cannula surface for at least a portion of a length of the cannula. A cover material may be in contact with the outer cannula surface, and may cover at least a portion of the optical fiber. A light diffuser may be disposed at a distal tip of the optical fiber.
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公开(公告)号：US20150370018A1
公开(公告)日：2015-12-24
申请号：US14313194
申请日：2014-06-24
Applicant: Novartis AG
Inventor： Eyad Ammari , Chenguang Diao
IPC: G02B6/38
CPC classification number: G02B6/3843 , B29C65/48 , B29C65/565 , G02B6/107 , G02B6/385 , G02B6/3851 , Y10T29/49773 , Y10T29/49828
Abstract: According to certain embodiments, a method comprises disposing a first nanofiber portion of a nanofiber and a first assisting fiber portion of an assisting fiber into a ferrule of a connector. A second assisting fiber portion is heated. The nanofiber and assisting fiber are moved such that a portion of the heated assisting fiber portion is disposed within the ferrule. According to other embodiments, a method comprises placing a fiber within a ferrule of a connector having a fixed point such that a fiber center is a fiber distance away from a receptacle center. The fiber distance between the fiber center and receptacle center is measured. An angular offset between the fixed point and fiber center is measured about the receptacle center. A rotation angle for the fiber distance and angular offset is determined. The ferrule is rotated relative to the connector according to the rotation angle.
Abstract translation: 根据某些实施例，一种方法包括将纳米纤维的第一纳米纤维部分和辅助纤维的第一辅助纤维部分设置在连接器的套圈中。 加热第二辅助纤维部分。 使纳米纤维和辅助纤维移动，使得加热的辅助纤维部分的一部分设置在套圈内。 根据其他实施例，一种方法包括将光纤放置在具有固定点的连接器的套圈内，使得光纤中心距离容器中心的光纤距离。 测量光纤中心和插座中心之间的光纤距离。 围绕容器中心测量固定点和纤维中心之间的角度偏移。 确定光纤距离和角度偏移的旋转角度。 套圈根据旋转角度相对于连接器旋转。
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公开(公告)号：US11135092B2
公开(公告)日：2021-10-05
申请号：US16218333
申请日：2018-12-12
Applicant: Novartis AG
Inventor： Chenguang Diao , Mark Harrison Farley , Alireza Mirsepassi , Ronald T. Smith , Dean Richardson
IPC: A61F9/008 , A61B18/22 , G02B6/38 , A61B90/30 , A61B18/24 , G02B6/02 , G02B6/42 , A61B18/00 , A61B18/20
Abstract: The present disclosure relates to a multi-core optical fiber cable (MCF). In some embodiments, an MCF comprises a plurality of cores surrounded by a cladding and a coating surrounding the cladding, wherein a refractive index of one or more of the plurality of cores is greater than a refractive index of the cladding. The MCF further comprises a probe comprising a probe tip coupled with a distal end of the MCF and a lens located at a distal end of the probe tip. In some embodiments, the lens is configured to translate laser light from the distal end of the MCF to create a multi-spot pattern of laser beams on a target surface and a distal end of the MCF terminates at an interface with the lens.
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Patent Agency Ranking
公开(公告)号：US10859748B2
公开(公告)日：2020-12-08
申请号：US16821474
申请日：2020-03-17
Applicant: Novartis AG
Inventor： Alireza Mirsepassi , Ronald T. Smith , Michael J. Papac , Chenguang Diao
IPC: G02B6/26 , F21V8/00 , A61F9/008 , G02B6/24 , A61B90/00 , A61F9/007 , A61B90/30 , G02B5/02 , A61B1/07
Abstract: An illumination fiber optics is provided that includes an optical fiber, configured to receive illumination light at a proximal end from a light source; and a light-scattering element, at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle. The illumination fiber optics can be prepared by providing an optical fiber, configured to receive illumination light at a proximal end from a light source; and creating a light-scattering element at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle.
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公开(公告)号：US10670815B2
公开(公告)日：2020-06-02
申请号：US15995568
申请日：2018-06-01
Applicant: Novartis AG
Inventor： Chenguang Diao , Alireza Mirsepassi , Michael J. Papac
Abstract: Improved optical fiber coupling reliability is realized by improving structures and materials used at the fiber joint. When ceramic ferrules are used at the fiber joint, the penetration of a UV-cured optical adhesive between the ceramic ferrules and the fiber ends is avoided or prevented, while an anti-reflective coating, an uncured optical adhesive, or a refractive index matching gel may be applied between the ceramic ferrules. When glass ferrules are used at the fiber joint, the UV-cured optical adhesive may be applied and fully cured between the glass ferrules and the fiber ends.
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公开(公告)号：US20190175405A1
公开(公告)日：2019-06-13
申请号：US16218333
申请日：2018-12-12
Applicant: Novartis AG
Inventor： Chenguang Diao , Mark Harrison Farley , Alireza Mirsepassi , Ronald T. Smith , Dean Richardson
Abstract: The present disclosure relates to a multi-core optical fiber cable (MCF). In some embodiments, an MCF comprises a plurality of cores surrounded by a cladding and a coating surrounding the cladding, wherein a refractive index of one or more of the plurality of cores is greater than a refractive index of the cladding. The MCF further comprises a probe comprising a probe tip coupled with a distal end of the MCF and a lens located at a distal end of the probe tip. In some embodiments, the lens is configured to translate laser light from the distal end of the MCF to create a multi-spot pattern of laser beams on a target surface and a distal end of the MCF terminates at an interface with the lens.
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公开(公告)号：US20190175273A1
公开(公告)日：2019-06-13
申请号：US16218382
申请日：2018-12-12
Applicant: Novartis AG
Inventor： Christopher Cook , Chenguang Diao , Mark Harrison Farley , Alireza Mirsepassi , Kambiz Parto , Ronald T. Smith
IPC: A61B18/22
Abstract: Certain aspects of the present disclosure provide a thermally robust laser probe assembly comprising a cannula, wherein one or more optical fibers extend at least partially through the cannula for transmitting laser light from a laser source to a target location. The probe assembly further comprises a lens housed in the cannula and a protective component press-fitted to the distal end of the cannula, wherein the lens is positioned between the one or more optical fibers and the protective component.
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公开(公告)号：US10295718B2
公开(公告)日：2019-05-21
申请号：US14973939
申请日：2015-12-18
Applicant: Novartis AG
Inventor： Alireza Mirsepassi , Ronald T. Smith , Michael J. Papac , Chenguang Diao
Abstract: An illumination fiber optics is provided that includes an optical fiber, configured to receive illumination light at a proximal end from a light source; and a light-scattering element, at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle. The illumination fiber optics can be prepared by providing an optical fiber, configured to receive illumination light at a proximal end from a light source; and creating a light-scattering element at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle.
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