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34 条记录 (耗时 0.023 秒)

    Ampk Activator
    12.
    发明申请
    Ampk Activator 审中-公开
    Ampk激活器

    公开(公告)号：US20070244202A1

    公开(公告)日：2007-10-18

    申请号：US11629486

    申请日：2005-06-21

    申请人： Takatoshi Murase

    发明人： Takatoshi Murase

    IPC分类号： A61K31/047 ,  A23L1/29 ,  C07C39/215 ,  C12N9/12

    CPC分类号： A61K31/05 ,  A23L33/105 ,  A61K36/752 ,  A61K2300/00

    摘要： The present invention relates to an AMPK activator containing resveratrol as an active ingredient. The present invention provides an AMPK activator containing, as an active ingredient, an ingredient contained in a naturally occurring material which has been consumed as a food or beverage for a long period of time, which exhibits high safety, which is readily available, which exhibits excellent processability, and which can be employed practically in humans.

    摘要翻译： 本发明涉及含有白藜芦醇作为活性成分的AMPK活化剂。 本发明提供一种AMPK活化剂，其含有作为食品或饮料长期消耗的天然物质中含有的成分作为活性成分，其表现出高度的安全性，其易于获得，其显示出 优异的加工性，并且可以在人类中实际使用。

    AMPK activating agent
    13.
    发明申请
    AMPK activating agent 审中-公开
    AMPK活化剂

    公开(公告)号：US20070054965A1

    公开(公告)日：2007-03-08

    申请号：US11480504

    申请日：2006-07-05

    申请人： Takatoshi Murase ,  Yoshihiko Minegishi

    发明人： Takatoshi Murase ,  Yoshihiko Minegishi

    IPC分类号： A61K31/122

    CPC分类号： A61K31/122

    摘要： The present invention relates to provision of AMPK activating agent, endurance enhancing agent, and antifatigue agent, which have rich history of use in foods, high safety, readily available, and high workability, a method of activating AMPK, and a method of preventing, treating and/or ameliorating a life-style-related disease. The present invention provides AMPK activating agent, endurance enhancing agent, and antifatigue agent, each of which contains nootkatone as an active agent. The present invention provides a method of activating AMPK characterized by administering nootkatone in an effective amount, and a method of preventing, treating and/or ameliorating a life-style-related disease characterized by administering nootkatone in an effective amount.

    摘要翻译： 本发明涉及具有食品使用丰富的历史，高安全性，容易获得和高加工性的AMPK活化剂，耐久性增强剂和抗疲劳剂的提供，AMPK活化方法， 治疗和/或改善与生活方式有关的疾病。 本发明提供AMPK活化剂，耐力增强剂和抗疲劳剂，其各自含有诺塔卡酮作为活性剂。 本发明提供一种活化AMPK的方法，其特征在于以有效量施用诺卡可酮，以及预防，治疗和/或改善以有效量施用诺塔卡酮为特征的生活方式相关疾病的方法。

    PPAR activator
    16.
    发明授权
    PPAR activator 有权
    PPAR活化剂

    公开(公告)号：US09301986B2

    公开(公告)日：2016-04-05

    申请号：US14001017

    申请日：2012-02-21

    申请人： Koichi Misawa ,  Hirofumi Takigawa ,  Takatoshi Murase

    发明人： Koichi Misawa ,  Hirofumi Takigawa ,  Takatoshi Murase

    IPC分类号： A61K36/48 ,  A61K36/185 ,  A61K36/06

    CPC分类号： A61K36/48 ,  A61K36/06 ,  A61K2236/19 ,  A61K2300/00

    摘要： Use of an organic solvent extract of a tempeh-fungus-fermented soybean product for the production of a PPARα and/or PPARδ activator. A method for activating PPARα and/or PPARδ, the method comprising administering an organic solvent extract of a tempeh-fungus-fermented soybean product to a subject, or feeding the organic solvent extract to the subject.

    摘要翻译： 使用真菌发酵大豆制品的有机溶剂提取物生产PPARα和/或PPARδ活化剂。 一种激活PPARα和/或PPARδ的方法，所述方法包括向受试者施用温豆发酵大豆产品的有机溶剂提取物，或将有机溶剂提取物喂给受试者。

    AMPK activating agent
    17.
    发明授权
    AMPK activating agent 有权
    AMPK活化剂

    公开(公告)号：US08829057B2

    公开(公告)日：2014-09-09

    申请号：US13008086

    申请日：2011-01-18

    申请人： Takatoshi Murase ,  Yoshihiko Minegishi

    发明人： Takatoshi Murase ,  Yoshihiko Minegishi

    IPC分类号： A61K31/12

    CPC分类号： A61K31/122

    摘要： A method for enhancing endurance and/or for removing fatigue by administering to a subject in need thereof a composition containing an effective amount of nootkatone. The method may be further combined with exercise.

    摘要翻译： 一种通过向有需要的受试者施用含有有效量的诺卡酮的组合物来增强耐力和/或消除疲劳的方法。 该方法可以进一步与运动组合。

    METHOD FOR ACTIVATING THE LIPID CATABOLIC METABOLISM IN ENTERIC EPITHELIUM AND IMPROVING THE LIPID METABOLISM IN ENTERIC EPITHELIUM
    19.
    发明申请
    METHOD FOR ACTIVATING THE LIPID CATABOLIC METABOLISM IN ENTERIC EPITHELIUM AND IMPROVING THE LIPID METABOLISM IN ENTERIC EPITHELIUM 审中-公开
    用于激活肠上皮细胞中脂质代谢物的方法，并改善肠系膜上皮脂肪代谢

    公开(公告)号：US20070287691A1

    公开(公告)日：2007-12-13

    申请号：US11781520

    申请日：2007-07-23

    申请人： Tadashi HASE ,  Takatoshi Murase ,  Hiroyuki Watanabe ,  Hidehiko Kondo

    发明人： Tadashi HASE ,  Takatoshi Murase ,  Hiroyuki Watanabe ,  Hidehiko Kondo

    IPC分类号： A61K31/231 ,  A61K31/575 ,  A61P3/04 ,  A61P3/10

    CPC分类号： A61K31/575 ,  A61K31/231

    摘要： Disclosed are a method for activating lipid metabolism in the small intestine epithelium and also a method for promoting accumulation of fatty acids into the small intestine epithelium, each of which features administering an effective amount of a diacylglycerol. Also disclosed are methods for improving various symptoms in diabetes, which have ingesting a diacylglycerol. Ingestion of the diacylglycerol leads to accumulation of the fatty acids in the small intestine. The fatty acids so accumulated promote induction of β-oxidation, thereby not only activating lipid catabolism but also making it difficult to allow lipids to accumulate as triacylglycerols. This series of actions eventually results in development of lowering action for blood remnant-like lipoprotein level and also lowering action for blood leptin level, and hence, lipid metabolism is improved. Further, energy consumption is enhanced by promoting the induction of β-oxidation and activating lipid catabolism.

    摘要翻译： 公开了一种在小肠上皮中激活脂质代谢的方法，还有一种促进脂肪酸向小肠上皮中积累的方法，其特征在于施用有效量的二酰基甘油。 还公开了改善摄取二酰基甘油的糖尿病各种症状的方法。 二酰基甘油的摄入导致脂肪酸在小肠中的积累。 如此积累的脂肪酸促进β-氧化的诱导，从而不仅激活脂质分解代谢，而且使得难以使脂质作为三酰基甘油积累。 这一系列动作最终导致降低血液残留样脂蛋白水平的作用，降低血液瘦素水平的作用，从而改善脂质代谢。 此外，通过促进β-氧化的诱导和激活脂质分解代谢来增加能量消耗。