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公开(公告)号：US12083092B2
公开(公告)日：2024-09-10
申请号：US17235140
申请日：2021-04-20
Applicant: Novartis AG , Katholieke Universiteit Leuven , Korea Research Institute of Chemical Technology
Inventor： Johan Neyts , Daniel Poon , Keith Bruce Pfister , Young-Sik Jung , Soo Bong Han , Yashwardhan R. Malpani , Prashant Chakrasali , Sang-Ho Lee , Chong-Kyo Lee , Chonsaeng Kim , Jin Soo Shin , Hae Soo Kim
IPC: A61K31/343 , A61P31/14 , C07D307/93
CPC classification number: A61K31/343 , A61P31/14 , C07D307/93
Abstract: This disclosure provides compounds of Formula (I)
as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.-
公开(公告)号：US10188649B2
公开(公告)日：2019-01-29
申请号：US15672568
申请日：2017-08-09
Applicant: Novartis AG
Inventor： Jeffrey T. Bagdanoff , Yu Ding , Wooseok Han , Zilin Huang , Qun Jiang , Xianming Jin , Xiang Kou , Patrick Lee , Mika Lindvall , Zhongcheng Min , Yue Pan , Sabina Pecchi , Keith Bruce Pfister , Daniel Poon , Vivek Rauniyar , Xiaojing Michael Wang , Qiong Zhang , Jianguang Zhou , Shejin Zhu
IPC: C07D241/20 , A61K31/4965 , A61K31/497 , A61K31/4436 , A61K31/4439 , A61K31/4545 , A61K31/506 , A61K31/5377 , A61K31/5383 , A61K31/553 , A61K45/06 , C07D401/04 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D498/04 , C07D213/73 , C07D401/06 , C07D401/12 , C07D403/06 , A61K31/44 , A61K31/4433 , A61K31/5355
Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.
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Patent Agency Ranking
公开(公告)号：US12286423B2
公开(公告)日：2025-04-29
申请号：US17235120
申请日：2021-04-20
Applicant: Novartis AG , Katholieke Universiteit Leuven , Korea Research Institute of Chemical Technology
Inventor： Johan Neyts , Daniel Poon , Keith Bruce Pfister , Young-Sik Jung , Soo Bong Han , Yashwardhan R. Malpani , Prashant Chakrasali , Bishyajit Kumar Biswas , Chong-Kyo Lee , Chonsaeng Kim , Jin Soo Shin , Hae Soo Kim
IPC: C07D405/12 , A61K45/06 , A61P31/14 , C07D307/93 , C07D405/14
Abstract: The invention provides compounds of Formula (I): as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.
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公开(公告)号：US20160280687A1
公开(公告)日：2016-09-29
申请号：US15179644
申请日：2016-06-10
Applicant: Novartis AG
Inventor： Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: C07D403/04 , C07D401/14 , C07D405/14
CPC classification number: C07D403/04 , A61K9/0053 , A61K31/4184 , A61K31/506 , A61K45/06 , C07D401/14 , C07D405/14 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号：US20160280686A1
公开(公告)日：2016-09-29
申请号：US15179385
申请日：2016-06-10
Applicant: Novartis AG
Inventor： Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: C07D403/04 , C07D405/14 , C07D401/14
CPC classification number: C07D403/04 , A61K9/0053 , A61K31/4184 , A61K31/506 , A61K45/06 , C07D401/14 , C07D405/14 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号：US20160122324A1
公开(公告)日：2016-05-05
申请号：US14994710
申请日：2016-01-13
Applicant: Novartis AG
Inventor： Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: C07D403/04
CPC classification number: C07D403/04 , A61K9/0053 , A61K31/4184 , A61K31/506 , A61K45/06 , C07D401/14 , C07D405/14 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号：US09314464B2
公开(公告)日：2016-04-19
申请号：US13931111
申请日：2013-06-28
Applicant: Novartis AG
Inventor： Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: A61K31/535 , A61K31/506 , C07D401/14 , C07D403/04 , A61K45/06 , C07D405/14
CPC classification number: C07D403/04 , A61K9/0053 , A61K31/4184 , A61K31/506 , A61K45/06 , C07D401/14 , C07D405/14 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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