公开(公告)号：US10660888B2

公开(公告)日：2020-05-26

申请号：US16210968

申请日：2018-12-05

Applicant: Novartis AG

Inventor： Jeffrey T. Bagdanoff ,  Yu Ding ,  Wooseok Han ,  Zilin Huang ,  Qun Jiang ,  Xianming Jin ,  Xiang Kou ,  Patrick Lee ,  Mika Lindvall ,  Zhongcheng Min ,  Yue Pan ,  Sabina Pecchi ,  Keith Bruce Pfister ,  Daniel Poon ,  Vivek Rauniyar ,  Xiaojing Michael Wang ,  Qiong Zhang ,  Jianguang Zhou ,  Shejin Zhu

IPC: A61K31/497 ,  C07D213/73 ,  C07D401/06 ,  C07D401/12 ,  C07D403/06 ,  A61K31/4436 ,  A61K31/4439 ,  A61K31/4545 ,  A61K31/4965 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/5383 ,  A61K31/553 ,  A61K45/06 ,  C07D241/20 ,  C07D401/04 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D413/14 ,  C07D498/04 ,  A61K31/44 ,  A61K31/4433 ,  A61K31/5355

Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.

公开(公告)号：US10188649B2

公开(公告)日：2019-01-29

申请号：US15672568

申请日：2017-08-09

Applicant: Novartis AG

Inventor： Jeffrey T. Bagdanoff ,  Yu Ding ,  Wooseok Han ,  Zilin Huang ,  Qun Jiang ,  Xianming Jin ,  Xiang Kou ,  Patrick Lee ,  Mika Lindvall ,  Zhongcheng Min ,  Yue Pan ,  Sabina Pecchi ,  Keith Bruce Pfister ,  Daniel Poon ,  Vivek Rauniyar ,  Xiaojing Michael Wang ,  Qiong Zhang ,  Jianguang Zhou ,  Shejin Zhu

IPC: C07D241/20 ,  A61K31/4965 ,  A61K31/497 ,  A61K31/4436 ,  A61K31/4439 ,  A61K31/4545 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/5383 ,  A61K31/553 ,  A61K45/06 ,  C07D401/04 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D413/14 ,  C07D498/04 ,  C07D213/73 ,  C07D401/06 ,  C07D401/12 ,  C07D403/06 ,  A61K31/44 ,  A61K31/4433 ,  A61K31/5355

Abstract: The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.