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公开(公告)号:US20090068109A1
公开(公告)日:2009-03-12
申请号:US11942126
申请日:2007-11-19
申请人: Anuk Das , Raymond Sweet , Ping Tsui , Michael Bardroff
发明人: Anuk Das , Raymond Sweet , Ping Tsui , Michael Bardroff
CPC分类号: C07K16/24 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要: The present invention relates to at least one novel anti-MCP-1 antibody, including isolated nucleic acids that encode at least one anti-MCP-1 antibody, MCP-1, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
摘要翻译: 本发明涉及至少一种新的抗MCP-1抗体,包括编码至少一种抗MCP-1抗体,MCP-1,载体,宿主细胞,转基因动物或植物的分离的核酸,以及制备方法 包括治疗组合物,方法和装置。
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公开(公告)号:US20060115475A1
公开(公告)日:2006-06-01
申请号:US11291140
申请日:2005-11-30
申请人: Jill Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill Giles-Komar , Theresa Goletz , David Knight , Roberta Lamb , Mouhamadou Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
发明人: Jill Carton , Shizhong Chen , Mark Cunningham , Anuk Das , Karen Duffy , Jill Giles-Komar , Theresa Goletz , David Knight , Roberta Lamb , Mouhamadou Mbow , Kristen Picha , Gopalan Raghunathan , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Nicole Stowell , Raymond Sweet , Shanrong Zhao
IPC分类号: A61K39/395 , C07K16/28
CPC分类号: C07K16/2896 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要: Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
摘要翻译: Toll样受体3(TLR3)拮抗剂,编码TLR3拮抗剂或其片段的多核苷酸,以及制备和使用前述物质的方法。
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公开(公告)号:US20060039913A1
公开(公告)日:2006-02-23
申请号:US11170453
申请日:2005-06-29
申请人: Anuk Das , Jill Carton
发明人: Anuk Das , Jill Carton
IPC分类号: A61K39/395 , C07K16/40
CPC分类号: C07K16/24 , A61K2039/505 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to at least one novel anti-MCP-1 antibodies, including isolated nucleic acids that encode at least one anti-MCP-1 antibody, MCP-1, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
摘要翻译: 本发明涉及至少一种新的抗MCP-1抗体,包括编码至少一种抗MCP-1抗体,MCP-1,载体,宿主细胞,转基因动物或植物的分离的核酸,以及制备方法 包括治疗组合物,方法和装置。
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公开(公告)号:US07371825B2
公开(公告)日:2008-05-13
申请号:US11170453
申请日:2005-06-29
申请人: Anuk Das , Jill M. Carton
发明人: Anuk Das , Jill M. Carton
CPC分类号: C07K16/24 , A61K2039/505 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to at least one novel anti-MCP-1 antibodies, including isolated nucleic acids that encode at least one anti-MCP-1 antibody, MCP-1, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
摘要翻译: 本发明涉及至少一种新的抗MCP-1抗体,包括编码至少一种抗MCP-1抗体,MCP-1,载体,宿主细胞,转基因动物或植物的分离的核酸,以及制备方法 包括治疗组合物,方法和装置。
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15.
公开(公告)号:US20050232923A1
公开(公告)日:2005-10-20
申请号:US10981936
申请日:2004-11-05
申请人: Li Yan , Marian Nakada , Anuk Das
发明人: Li Yan , Marian Nakada , Anuk Das
IPC分类号: A61K20060101 , A61K31/137 , A61K31/445 , A61K31/473 , A61K31/573 , A61K38/18 , A61K38/54 , A61K39/395 , A61K45/06 , C07K16/24
CPC分类号: A61K31/573 , A61K31/137 , A61K31/445 , A61K31/473 , A61K38/00 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/24 , C07K2317/21 , C07K2317/73 , A61K2300/00
摘要: The present invention relates to methods for treating at least one MCP-1 related condition or pathology, including therapeutic compositions, methods and devices.
摘要翻译: 本发明涉及用于治疗至少一种MCP-1相关病症或病理学的方法,包括治疗组合物,方法和装置。
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公开(公告)号:US20050025822A1
公开(公告)日:2005-02-03
申请号:US10856559
申请日:2004-05-27
申请人: Frances Wong , Anuk Das , Jonathan Seideman , Luke Guo , Anthony Huang
发明人: Frances Wong , Anuk Das , Jonathan Seideman , Luke Guo , Anthony Huang
CPC分类号: A61K9/0078 , A61K9/127 , A61K9/1271
摘要: A method for administering a therapeutic or diagnostic agent to a subject is described. The method includes providing a suspension of liposomes comprised of one or more of vesicle-forming lipids selected from (i) a vesicle-forming lipid derivatized with a hydrophilic polymer and (ii) a neutral lipopolymer, said liposomes being associated with said therapeutic or diagnostic agent, forming an aerosol of said liposome suspension; and administering the aerosol to the subject by inhalation. The liposome formulation delivers intact liposomal particles to the respiratory tract of said subject to form a depot of therapeutic agent therein with no observable provocation of an immune response, as measured by neutrophil or macrophage cell count in the lung after administration.
摘要翻译: 描述了向受试者施用治疗剂或诊断剂的方法。 该方法包括提供脂质体的悬浮液,其由一种或多种形成囊泡的脂质组成,所述脂质体选自(i)用亲水性聚合物衍生的囊泡形成脂质和(ii)中性脂质聚合物,所述脂质体与所述治疗或诊断相关联 形成所述脂质体悬浮液的气溶胶; 并通过吸入将烟雾剂施用于受试者。 脂质体制剂将完整的脂质体颗粒递送到所述受试者的呼吸道,以在其中形成治疗剂的贮库,其中不存在可观察到的免疫应答挑衅,如通过给药后肺中的嗜中性粒细胞或巨噬细胞细胞计数所测量的。
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