公开(公告)号：US11699580B2

公开(公告)日：2023-07-11

申请号：US16930388

申请日：2020-07-16

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Guangtao Li ,  Guangming Huang ,  Jason Duncan ,  Xin Li ,  Ewa Sokol ,  Xin Yan

IPC: H01J49/04 ,  H01J49/00 ,  G01N27/62 ,  H01J49/42

CPC classification number: H01J49/04 ,  G01N27/62 ,  H01J49/0018 ,  H01J49/0031 ,  H01J49/045 ,  H01J49/0445 ,  H01J49/4205 ,  Y10T436/24

Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.

公开(公告)号：US20220199384A9

公开(公告)日：2022-06-23

申请号：US16930388

申请日：2020-07-16

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Guangtao Li ,  Guangming Huang ,  Jason Duncan ,  Xin Li ,  Ewa Sokol ,  Xin Yan

IPC: H01J49/04 ,  G01N27/62 ,  H01J49/00

Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.

公开(公告)号：US20190057856A1

公开(公告)日：2019-02-21

申请号：US15769998

申请日：2016-10-21

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Jason Duncan ,  Joshua Wiley

IPC: H01J49/42 ,  H01J49/00

Abstract: The invention generally relates to ion traps and methods of use thereof. In certain embodiments, the invention provides a system that includes a mass spectrometer including an ion trap, and a central processing unit (CPU). The CPU has storage that is coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply a constant radio frequency (RF) signal to the ion trap, and apply a first alternating current (AC) signal to the ion trap the frequency of which varies as a function of time.

公开(公告)号：US09500623B2

公开(公告)日：2016-11-22

申请号：US14052815

申请日：2013-10-14

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Jason Duncan ,  Guangming Huang ,  Guangtao Li ,  Xin Yan ,  Ewa Sokol ,  Xin Li

IPC: G01N24/00 ,  G01N27/62 ,  H01J49/04

CPC classification number: H01J49/045 ,  G01N27/62 ,  H01J49/0018 ,  H01J49/0445 ,  Y10T436/24

Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.

公开(公告)号：US20160118236A1

公开(公告)日：2016-04-28

申请号：US14936197

申请日：2015-11-09

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Jason Duncan ,  Guangming Huang ,  Guangtao Li ,  Xin Yan ,  Ewa Sokol ,  Xin Li

IPC: H01J49/04 ,  H01J49/42 ,  H01J49/00

CPC classification number: H01J49/04 ,  G01N27/62 ,  H01J49/0031 ,  H01J49/0445 ,  H01J49/4205 ,  Y10T436/24

Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.

公开(公告)号：US09184036B2

公开(公告)日：2015-11-10

申请号：US13887911

申请日：2013-05-06

Applicant: Purdue Research Foundation

Inventor： Robert Graham Cooks ,  Jason Duncan ,  Guangming Huang ,  Guangtao Li ,  Xin Yan ,  Ewa Sokol ,  Xin Li

IPC: G01N24/00 ,  H01J49/04 ,  G01N27/62 ,  H01J49/00

CPC classification number: H01J49/04 ,  G01N27/62 ,  H01J49/0031 ,  H01J49/0445 ,  H01J49/4205 ,  Y10T436/24

Abstract: The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface.

Abstract translation: 本发明一般涉及用于使离子产生与不连续大气界面的循环同步的方法和装置。 在某些实施方案中，本发明提供了一种用于分析样品的系统，该样品包括产生样品离子的质谱探针，不连续大气界面和质量分析仪，其中该系统配置成使得离子形成与 不连续大气界面。