公开(公告)号：US11867596B2

公开(公告)日：2024-01-09

申请号：US17707214

申请日：2022-03-29

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： Xue Zhen ,  Philippe Pierre Joseph Buhlmann ,  Steven J. Koester ,  Justin Theodore Nelson

IPC: G01N33/497 ,  G01N27/12 ,  G01N27/22

CPC classification number: G01N33/497 ,  G01N27/125 ,  G01N27/227 ,  G01N2610/00

Abstract: Embodiments include chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is provided. The medical device can include a graphene varactor, including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through electrostatic interactions between a partial positive charge on hydrogen atoms of one or more hydrocarbons of the self-assembled monolayer and a π-electron system of graphene. The self-assembled monolayer can include one or more substituted porphyrins or substituted metalloporphyrins, or derivatives thereof. Other embodiments are also included herein.

公开(公告)号：US11293914B2

公开(公告)日：2022-04-05

申请号：US16393177

申请日：2019-04-24

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA ,  Boston Scientific Scimed, Inc.

Inventor： Xue Zhen ,  Philippe Pierre Joseph Buhlmann ,  Steven J. Koester ,  Justin Theodore Nelson

IPC: G01N33/497 ,  G01N27/22 ,  G01N27/12

Abstract: Embodiments include chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is provided. The medical device can include a graphene varactor, including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through electrostatic interactions between a partial positive charge on hydrogen atoms of one or more hydrocarbons of the self-assembled monolayer and a it-electron system of graphene. The self-assembled monolayer can include one or more substituted porphyrins or substituted metalloporphyrins, or derivatives thereof. Other embodiments are also included herein.

公开(公告)号：US20210356457A1

公开(公告)日：2021-11-18

申请号：US17387503

申请日：2021-07-28

Applicant: Boston Scientific Scimed, Inc. ,  REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： Xue Zhen ,  Philippe Pierre Joseph Buhlmann ,  Steven Koester ,  Yao Zhang ,  Justin Theodore Nelson

IPC: G01N33/53 ,  G01N27/12 ,  G01N27/22

Abstract: Embodiments herein relate to chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is included. The medical device can include a graphene varactor. The graphene varactor can include a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through π-π stacking interactions. The self-assembled monolayer can provide a Langmuir theta value of at least 0.9. The self-assembled monolayer can include polycyclic aromatic hydrocarbons, tetraphenylporphyrins or derivatives thereof, metallotetraphenylporphyrins, or aromatic cyclodextrins. Other embodiments are also included herein.

公开(公告)号：US11079371B2

公开(公告)日：2021-08-03

申请号：US16280635

申请日：2019-02-20

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA ,  Boston Scientific Scimed, Inc.

Inventor： Xue Zhen ,  Philippe Pierre Joseph Buhlmann ,  Steven J. Koester ,  Yao Zhang ,  Justin Theodore Nelson

IPC: G01N33/53 ,  G01N27/12 ,  G01N27/22 ,  A61B5/08 ,  G01N27/414

Abstract: Embodiments herein relate to chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is included. The medical device can include a graphene varactor. The graphene varactor can include a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through π-π stacking interactions. The self-assembled monolayer can provide a Langmuir theta value of at least 0.9. The self-assembled monolayer can include polycyclic aromatic hydrocarbons, tetraphenylporphyrins or derivatives thereof, metallotetraphenylporphyrins, or aromatic cyclodextrins. Other embodiments are also included herein.

公开(公告)号：US20210057526A1

公开(公告)日：2021-02-25

申请号：US16996537

申请日：2020-08-18

Applicant: Boston Scientific Scimed, Inc. ,  REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： Xue Zhen ,  Philippe Pierre Joseph Buhlmann ,  Steven J. Koester

IPC: H01L29/16 ,  H01L29/93 ,  A61B5/08 ,  C01B32/194 ,  G01N27/22 ,  G01N27/04

Abstract: Embodiments herein relate to chemical sensors, devices and systems including the same, and related methods. In an embodiment, a medical device is included having a graphene varactor including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through non-covalent interactions between the self-assembled monolayer and a π-electron system of graphene. The self-assembled monolayer includes one or more pillarenes, substituted pillarenes, calixarenes, substituted calixarenes, peralkylated cyclodextrins, substituted peralkylated cyclodextrins, pyrenes, or substituted pyrenes, or derivatives thereof. Other embodiments are also included herein.