公开(公告)号：US20090018606A1

公开(公告)日：2009-01-15

申请号：US12236395

申请日：2008-09-23

申请人： Kurt D. Sparks ,  Charles R. Brynelsen ,  Mir A. Imran

发明人： Kurt D. Sparks ,  Charles R. Brynelsen ,  Mir A. Imran

IPC分类号： A61N1/05

CPC分类号： A61N1/0509 ,  A61N1/0517 ,  A61N1/36007

摘要： Devices, systems and methods are provided for electrical stimulation of a body organ, particularly within the gastrointestinal tract. In preferred embodiments, the stomach is the organ within the gastrointestinal tract which is targeted for such stimulation. A guide wire or other delivery device is positioned within the body so as to transect the stomach wall. Devices and systems are then advanced over the guide wire for attachment to the stomach wall. The guide wire may be placed by endoscopic, open, laparoscopic or a modified percutaneous approach. In a modified percutaneous approach, the stomach is accessed without the use of general anesthesia by advancing a needle through the abdomen, transecting the stomach wall with the needle and advancing the guide wire through the needle. In some embodiments, particularly for use in obese patients, the modified percutaneous approach includes advancing a trocar through the tissue of the patient toward the outer surface of the organ and advancing the needle through the trocar prior to transecting the wall with the needle.

摘要翻译： 设备，系统和方法用于电刺激身体器官，特别是在胃肠道内。 在优选的实施方案中，胃是针对这种刺激的胃肠道内的器官。 引导线或其他输送装置定位在体内以便横切胃壁。 然后，装置和系统在引导线上前进以附接到胃壁。 导丝可以通过内窥镜，开放式，腹腔镜或经修改的经皮方法来放置。 在改进的经皮途径中，通过使针穿过腹部，用针切开胃壁并使引导线穿过针而进入胃而不使用全身麻醉。 在一些实施方案中，特别是用于肥胖患者中，经修改的经皮方法包括使套针针穿过患者的组织朝向器官的外表面，并且在用针横切壁之前使针穿过套针针。

公开(公告)号：US08702679B2

公开(公告)日：2014-04-22

申请号：US10865231

申请日：2004-06-10

申请人： Robert K. Deckman ,  Erik Thai ,  Amiel R. Aguilar ,  Benjamin J. Clark ,  Sergio Salinas ,  Daniel E. Francis ,  Kurt D. Sparks

发明人： Robert K. Deckman ,  Erik Thai ,  Amiel R. Aguilar ,  Benjamin J. Clark ,  Sergio Salinas ,  Daniel E. Francis ,  Kurt D. Sparks

IPC分类号： A61M25/00

CPC分类号： A61M25/0662 ,  A61B2017/22042 ,  A61B2017/22094 ,  A61M25/0045 ,  A61M25/005 ,  A61M2025/0681 ,  A61M2025/0687

摘要： Interventional catheter-based systems and methods are described herein for use in generating an initial pathway through vascular occlusions. The catheter systems generally include two elements. A first element is a Blunt Dissection Catheter including a manually actuated assembly located at the distal tip of the Blunt Dissection Catheter that performs blunt dissection in the vascular occlusion to produce a dissection track, or small pathway through the occlusion. The second element is a Sheath Catheter that serves as a conduit within which the Blunt Dissection Catheter is freely advanced, retracted and rotated. The first and second elements are used in some combination to cross vascular occlusions in both the coronary and peripheral vasculature.

摘要翻译： 本文描述介入性导管基系统和方法用于通过血管闭塞产生初始途径。 导管系统通常包括两个元件。 第一个要素是平坦解剖导管，其包括位于钝性解剖导管的远端的手动致动组件，其在血管闭塞中进行钝性解剖以产生解剖轨迹，或通过闭塞的小通路。 第二个要素是鞘鞘导管，用作导管，平头解剖导管可自由前进，缩回和旋转。 第一和第二元素被用于某种组合以在冠状动脉和外周脉管系统中交叉血管闭塞。

公开(公告)号：US07004173B2

公开(公告)日：2006-02-28

申请号：US10010410

申请日：2001-12-05

申请人： Kurt D. Sparks ,  Jeffrey L. Emery ,  Brent D. Seybold ,  David J. Kupiecki ,  C. Danielle Pinson ,  Allen W. Madsen ,  Michael D. Keleher ,  Sergio Salinas ,  Benjamin J. Clark ,  Matthew R. Selmon

发明人： Kurt D. Sparks ,  Jeffrey L. Emery ,  Brent D. Seybold ,  David J. Kupiecki ,  C. Danielle Pinson ,  Allen W. Madsen ,  Michael D. Keleher ,  Sergio Salinas ,  Benjamin J. Clark ,  Matthew R. Selmon

IPC分类号： A61B19/00

CPC分类号： A61B17/320783 ,  A61B17/3207 ,  A61B90/37 ,  A61B2017/00252 ,  A61B2017/22077 ,  A61B2017/22094 ,  A61B2017/22095 ,  A61B2090/378 ,  A61B2090/3782

摘要： A catheter system and corresponding methods are provided for accessing a blood vessel true lumen from a sub-intimal plane of the vessel. The catheter system includes visualization elements for determining the orientation of the true lumen with respect to the sub-intimal plane at an identified entry site from a position in the sub-intimal plane. The entry site is distal to a chronic total occlusion (CTO). The catheter system also includes a system for physically securing tissue of the sub-intimal plane at the entry site to the catheter system. The attaching system reduces or eliminates catheter float within the sub-intimal space. The catheter system further includes re-entry devices to establish and maintain a path from the sub-intimal plane back into the vessel true lumen.

公开(公告)号：US5823996A

公开(公告)日：1998-10-20

申请号：US608641

申请日：1996-02-29

申请人： Kurt D. Sparks

发明人： Kurt D. Sparks

IPC分类号： A61F2/958 ,  A61M5/14 ,  A61M25/00 ,  A61M29/02 ,  A61M29/00

CPC分类号： A61M25/104 ,  A61M25/1002 ,  A61M2025/0057 ,  A61M2025/0183 ,  A61M2025/105 ,  A61M2025/1084 ,  A61M5/14

摘要： Apparatus and method is disclosed relating to an infusion catheter for treating a subject region with a treatment solution. A guide catheter allows the infusion catheter to be inserted into the subject and placed near a treatment region within the vascular system. A solution source is used to selectively inflate an infusion device. A passageway in the catheter body extends to an infusion device which has inner and outer chambers. Holes in a wall of the inner chamber route solution into the outer chamber and holes in the wall of the outer chamber route the solution into a subject vasculature. Solution pressure in the inner chamber is greater then the solution pressure in the outer chamber due to the relatively greater area of the holes in the outer chamber wall.

摘要翻译： 公开了一种用于用治疗溶液治疗受试者区域的输注导管的装置和方法。 引导导管允许输注导管插入受试者并放置在血管系统内的治疗区域附近。 溶液源用于选择性地充气输注装置。 导管主体中的通道延伸到具有内室和外腔的输注装置。 在内室的壁中的孔将溶液引入外室，并且外室的壁中的孔将溶液引导到主体脉管系统中。 由于外室壁中的孔的面积相对较大，内腔中的溶液压力大于外室中的溶液压力。

公开(公告)号：US20120283717A1

公开(公告)日：2012-11-08

申请号：US13550392

申请日：2012-07-16

申请人： Hugh R. Sharkey ,  Ramiro Reyes ,  Kurt D. Sparks

发明人： Hugh R. Sharkey ,  Ramiro Reyes ,  Kurt D. Sparks

IPC分类号： A61B18/04

CPC分类号： A61B18/04 ,  A61B2017/3425 ,  A61B2017/4216 ,  A61B2017/4225 ,  A61B2018/00005 ,  A61B2018/00285 ,  A61B2018/00559 ,  A61B2018/048

摘要： A method and system of providing therapy to a patient's uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; a seal disposed at a distal region of the access tool and adapted to seal the access tool against an interior cervical os; a sealing indicator adapted to provide a user with an indication that the seal has sealed the access tool with the interior cervical os; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.

摘要翻译： 为患者子宫提供治疗的方法和系统。 该系统具有内腔的进入工具，当进入工具插入通过子宫颈管道时，进入工具适于插入人宫颈管以将管腔的开口放置在子宫内; 设置在所述进入工具的远侧区域处并适于将所述进入工具密封抵靠内部颈部口的密封件; 密封指示器，其适于向使用者提供所述密封件已经将所述进入工具与所述内部宫颈口密封的指示; 以及适于将可冷凝蒸气通过所述进入工具输送到子宫的蒸汽递送机构，所述可冷凝蒸气适于在子宫内冷凝。

公开(公告)号：US08221401B2

公开(公告)日：2012-07-17

申请号：US12197084

申请日：2008-08-22

申请人： Hugh R. Sharkey ,  Ramiro Reyes ,  Kurt D. Sparks

发明人： Hugh R. Sharkey ,  Ramiro Reyes ,  Kurt D. Sparks

IPC分类号： A61B18/18

CPC分类号： A61B18/04 ,  A61B2017/3425 ,  A61B2017/4216 ,  A61B2017/4225 ,  A61B2018/00005 ,  A61B2018/00285 ,  A61B2018/00559 ,  A61B2018/048

摘要： A method and system of providing therapy to a patient's uterus. The method includes the steps of inserting an access tool through a cervix and a cervical canal into the uterus; actively cooling the cervical canal; delivering vapor through the access tool lumen into the uterus; and condensing the vapor on tissue within the uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; an active cooling mechanism adapted to cool the cervical canal, the active cooling mechanism having a coolant source; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.

摘要翻译： 为患者子宫提供治疗的方法和系统。 该方法包括将进入工具通过子宫颈和子宫颈管插入子宫的步骤; 积极冷却宫颈管; 通过进入工具内腔将蒸气输送到子宫中; 并将蒸气冷凝在子宫内的组织上。 该系统具有内腔的进入工具，当进入工具插入通过子宫颈管道时，进入工具适于插入人宫颈管以将管腔的开口放置在子宫内; 主动冷却机构，其适于冷却颈管，主动冷却机构具有冷却剂源; 以及适于将可冷凝蒸气通过所述进入工具输送到子宫的蒸汽递送机构，所述可冷凝蒸气适于在子宫内冷凝。

公开(公告)号：US20090054868A1

公开(公告)日：2009-02-26

申请号：US12197084

申请日：2008-08-22

申请人： Hugh R. Sharkey ,  Ramiro Reyes ,  Kurt D. Sparks

发明人： Hugh R. Sharkey ,  Ramiro Reyes ,  Kurt D. Sparks

IPC分类号： A61M31/00

CPC分类号： A61B18/04 ,  A61B2017/3425 ,  A61B2017/4216 ,  A61B2017/4225 ,  A61B2018/00005 ,  A61B2018/00285 ,  A61B2018/00559 ,  A61B2018/048

摘要： A method and system of providing therapy to a patient's uterus. The method includes the steps of inserting an access tool through a cervix and a cervical canal into the uterus; actively cooling the cervical canal; delivering vapor through the access tool lumen into the uterus; and condensing the vapor on tissue within the uterus. The system has an access tool with a lumen, the access tool being adapted to be inserted through a human cervical canal to place an opening of the lumen within a uterus when the access tool is inserted through the cervical canal; an active cooling mechanism adapted to cool the cervical canal, the active cooling mechanism having a coolant source; and a vapor delivery mechanism adapted to deliver condensable vapor through the access tool to the uterus, the condensable vapor being adapted to condense within the uterus.

摘要翻译： 为患者子宫提供治疗的方法和系统。 该方法包括将进入工具通过子宫颈和子宫颈管插入子宫的步骤; 积极冷却宫颈管; 通过进入工具内腔将蒸气输送到子宫中; 并将蒸气冷凝在子宫内的组织上。 该系统具有内腔的进入工具，当进入工具插入通过子宫颈管道时，进入工具适于插入人宫颈管以将管腔的开口放置在子宫内; 主动冷却机构，其适于冷却颈管，主动冷却机构具有冷却剂源; 以及适于将可冷凝蒸气通过所述进入工具输送到子宫的蒸汽递送机构，所述可冷凝蒸气适于在子宫内冷凝。

公开(公告)号：US20090030475A1

公开(公告)日：2009-01-29

申请号：US12176950

申请日：2008-07-21

申请人： Charles R. Brynelsen ,  Michael F. Wei ,  Kurt D. Sparks ,  Kenneth L. Wong ,  George Pool

发明人： Charles R. Brynelsen ,  Michael F. Wei ,  Kurt D. Sparks ,  Kenneth L. Wong ,  George Pool

IPC分类号： A61N1/05

CPC分类号： A61B17/0469 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61N1/05 ,  A61N1/36007

摘要： Gastric stimulation devices, systems and methods are provided, particularly for stimulating a gastric organ having an internal cavity. Such devices and systems are typically implanted outside of the gastric organ while the environment of the internal cavity is probed and monitored by one or more sensors. The sensor information may be used to affect the stimulation signals provided to the gastric organ by the devices and systems. Such feedback integration assists in providing treatments and stimulation programs that are tailored to the needs of the individual patient.

摘要翻译： 提供胃刺激装置，系统和方法，特别是用于刺激具有内腔的胃器官。 这种装置和系统通常植入胃器官外部，同时内窥镜的环境被一个或多个传感器探测和监测。 传感器信息可用于影响由装置和系统提供给胃器官的刺激信号。 这种反馈整合有助于提供针对个体患者需求量身定制的治疗和刺激方案。

公开(公告)号：US06428552B1

公开(公告)日：2002-08-06

申请号：US09768376

申请日：2001-01-22

申请人： Kurt D. Sparks

发明人： Kurt D. Sparks

IPC分类号： A61B1722

CPC分类号： A61B17/3207 ,  A61B2017/22001 ,  A61B2017/22042 ,  A61B2017/22044 ,  A61B2017/22094 ,  A61B2017/320044 ,  A61M25/09 ,  A61M2025/09175

摘要： An apparatus for treating occlusions. In one embodiment, the apparatus comprises an outer catheter shaft with at least one axial lumen therethrough, wherein the outer catheter shaft comprises a distal end having an outer diameter, and an inner catheter shaft having an average diameter slidably disposed in the at least one axial lumen of the outer catheter shaft. The inner catheter shaft comprises at least one axial lumen therethrough, and an a traumatic, tapered protuberance comprising a distal end and a proximal end, wherein a diameter of the a traumatic, tapered protuberance tapers upward from the average diameter at the distal end to a greatest diameter at the proximal end. The embodiment further comprises a guidewire slidably disposed in the at least one axial lumen of the inner catheter shaft, wherein the guidewire is advanced through the body lumen into the occlusion. When the outer catheter shaft is advanced distally to closely approach the proximal end of the atraumatic, tapered protuberance, the outer catheter shaft and the inner catheter shaft present a relatively smooth tapering surface to the occlusion such that the outer catheter shaft may enter the occlusion.

摘要翻译： 一种治疗闭塞的装置。 在一个实施例中，该装置包括具有穿过其中的至少一个轴向腔的外导管轴，其中外导管轴包括具有外径的远端，以及内导管轴，其具有可滑动地设置在至少一个轴向 外导管轴的内腔。 内导管轴包括穿过其中的至少一个轴向腔，以及包括远端和近端的创伤性锥形突起，其中创伤性锥形突起的直径从远端的平均直径向上逐渐变细 近端最大直径。 该实施例还包括可滑动地设置在内导管轴的至少一个轴向内腔中的导丝，其中导丝通过体腔前进到闭塞。 当外导管轴向远侧推进以接近无创的锥形突起的近端时，外导管轴和内导管轴呈现相对平滑的锥形表面到闭塞，使得外导管轴可进入闭塞。