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公开(公告)号：US20120119490A1
公开(公告)日：2012-05-17
申请号：US13356953
申请日：2012-01-24
CPC分类号： E21B17/085 , F16L37/138
摘要： A marine riser assembly having a first tubular member having an external surface with a plurality of first axially spaced formations, a second tubular member having an external surface with a plurality of second axially spaced formations thereon, a segmented ring in surrounding relationship to the first and second tubular members, the segmented ring having an inner surface with a plurality of formations engageable with the formations on the first and second tubular members, the engageable formations serving to urge the first and second tubular members toward each other when the segmented ring is subjected to radially inwardly directed compressive forces, a sleeve in surrounding relationship to force the engageable formations together and a seal assembly for sealing against external and internal pressure.
摘要翻译： 一种具有第一管状构件的海洋提升管组件，该第一管状构件具有多个第一轴向间隔的结构的外表面，第二管状构件，具有在其上具有多个第二轴向间隔的结构的外表面，与第一和第 第二管状构件，分段环具有内表面，其具有可与第一和第二管状构件上的结构接合的多个结构，所述可接合构造用于在分段环经受第一和第二管状构件时将第一和第二管状构件朝向彼此推动 径向向内的压缩力，围绕关系的套筒，以将可接合的结构压在一起，以及用于密封抵抗外部和内部压力的密封组件。
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公开(公告)号：US20110201012A1
公开(公告)日：2011-08-18
申请号：US12907370
申请日：2010-10-19
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/118
摘要： Provided is a method for detecting metastases of epithelial cancers, comprising detecting in non-primary tissue overexpression of a nucleic acid of KS1/4, or detecting in non-primary tissue overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx, the overexpression of a nucleic acid of KS1/4, or the overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx in non-primary tissue being correlated with metastases of epithelial cancers.
摘要翻译： 提供了一种用于检测上皮癌转移的方法，包括在非原代组织中检测KS1 / 4核酸的过表达，或检测非小细胞组织过表达KS1 / 4和PIP核酸的组合， KS1 / 4，PIP和mam核酸或KS1 / 4和lunx核酸的PIP和mam的核酸的KS1 / 4和mam的核酸，KS1 / 4的核酸的过表达 或KS1 / 4，PIP和mam核酸或核酸的核酸的PIP和mam的核酸的KS1 / 4和mam的核酸的KS1 / 4和PIP的核酸的组合的过表达或核酸 KS1 / 4的酸和非原发性组织中的lunx与上皮癌的转移相关。
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13.发明授权Isolated nucleic acids encoding a wheat glutathione transferase, plants transformed therewith and methods of use thereof 失效分离的编码小麦谷胱甘肽转移酶的核酸，转化的植物及其使用方法公开(公告)号：US06730828B1
公开(公告)日：2004-05-04
申请号：US09508710
申请日：2000-07-10
申请人： David J. Cole , Ian Cummins , Robert Edwards
发明人： David J. Cole , Ian Cummins , Robert Edwards
IPC分类号： A01H500
CPC分类号： C12N9/1088 , C12N15/8209 , C12N15/8274
摘要： This invention relates to isolated polynucleotides encoding a wheat glutathione transferase subunit (GST) as well as host cells and plants transformed therewith. The invention also relates to methods of using the isolated polynucleotides to make herbicide resistant plant cells and plants, and to methods of selecting transformed plant cells in the presence of an herbicide.
摘要翻译： 本发明涉及编码小麦谷胱甘肽转移酶亚基（GST）的分离的多核苷酸以及宿主细胞和转化的植物。 本发明还涉及使用分离的多核苷酸来制备除草剂抗性植物细胞和植物的方法，以及在除草剂存在下选择转化的植物细胞的方法。
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公开(公告)号：US06228154B1
公开(公告)日：2001-05-08
申请号：US09471562
申请日：1999-12-23
申请人： James L. Pakkala , Guang Yu , David J. Cole
发明人： James L. Pakkala , Guang Yu , David J. Cole
IPC分类号： B01D4710
CPC分类号： B01D47/10 , B05B14/46 , B05B14/468 , Y10S55/46
摘要： A discrete pod gas scrubber system for removing contaminants from the air of a work area, such as a paint spray booth. Each scrubber pod includes an inlet section having opposed converging planar walls and side walls, an intermediate section having opposed diverging walls and side walls communicating with the inlet section through a reduced diameter venturi, and an outlet section having a bottom wall perpendicular to the longitudinal axis of the scrubber pod, a diverging top wall and an end wall. The end wall includes an orifice opening and orifice plates for adjusting the orifice opening and the combined lengths of the aligned scrubber pods are between fifty and ninety percent of the total length of the scrubber system, more preferably between sixty percent and eighty five percent of the total length. The scrubber system of this invention significantly reduces the noise generated in the work area normally located above the gas scrubber system.
摘要翻译： 独立的荚式气体洗涤器系统，用于从工作区域的空气中除去污染物，如喷漆室。 每个洗涤器荚包括具有相对的会聚平面壁和侧壁的入口部分，具有相对的发散壁和通过直径减小的文丘里管与入口部分连通的侧壁的中间部分，以及具有垂直于纵向轴线的底壁的出口部分 的洗涤器荚，发散的顶壁和端壁。 端壁包括孔口和用于调节孔口的孔板，并且对齐的洗涤器荚的组合长度在洗涤器系统的总长度的百分之五十到百分之九十之间，更优选为百分之六十至百分之八十五 总长度。 本发明的洗涤器系统显着降低了通常位于气体洗涤器系统上方的工作区域中产生的噪声。
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公开(公告)号：US07699354B2
公开(公告)日：2010-04-20
申请号：US11414315
申请日：2006-04-28
IPC分类号： F16L17/00
CPC分类号： E21B17/085 , F16L37/138
摘要： A marine riser assembly having a first tubular member having an external surface with a plurality of first axially spaced formations, a second tubular member having an external surface with a plurality of second axially spaced formations thereon, a segmented ring in surrounding relationship to the first and second tubular members, the segmented ring having an inner surface with a plurality of formations engageable with the formations on the first and second tubular members, the engageable formations serving to urge the first and second tubular members toward each other when the segmented ring is subjected to radially inwardly directed compressive forces, a sleeve in surrounding relationship to force the engageable formations together and a seal assembly for sealing against external and internal pressure.
摘要翻译： 一种具有第一管状构件的海洋提升管组件，该第一管状构件具有多个第一轴向间隔的结构的外表面，第二管状构件，具有在其上具有多个第二轴向间隔的结构的外表面， 第二管状构件，分段环具有内表面，其具有可与第一和第二管状构件上的结构接合的多个结构，所述可接合构造用于在分段环经受第一和第二管状构件时将第一和第二管状构件朝向彼此推动 径向向内的压缩力，围绕关系的套筒，以将可接合的结构压在一起，以及用于密封抵抗外部和内部压力的密封组件。
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16.发明申请Enhanced Detection of Rna Using a Panel of Truncated Gene-Specific Primers for Reverse Transcription 有权使用截断的基因特异性引物组进行逆转录增强的Rna检测公开(公告)号：US20080233563A1
公开(公告)日：2008-09-25
申请号：US10590891
申请日：2005-02-25
CPC分类号： C12Q1/6886 , C12Q2600/158
摘要： The present invention provides truncated gene-specific primers in panels that can be used during the reverse transcription step of RT-PCR to increase signal detection of cancer gene markers in a tissue sample. Also provided are forward and reverse primers for RT-PCR. Methods of using the primers are also provided.
摘要翻译： 本发明提供了可在RT-PCR的逆转录步骤期间使用的片段中的截短的基因特异性引物，以增加组织样品中癌症基因标记的信号检测。 还提供了用于RT-PCR的正向和反向引物。 还提供了使用引物的方法。
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公开(公告)号：US07241080B2
公开(公告)日：2007-07-10
申请号：US10805835
申请日：2004-03-22
IPC分类号： B65G53/66
CPC分类号： B05B7/1459 , F04F1/02 , F04F1/18 , F04F5/54
摘要： A pump for transferring particulate material from a source to a remote location, including a particulate chamber having open ends, check valves at the open ends, a vacuum source connected to the chamber adjacent one end, a gas source at the opposed end of the chamber and a control which alternatively connects the vacuum to the chamber to draw particulate material from the source to the chamber and connecting the gas under pressure to drive the particulate material to the remote location. In a preferred embodiment, the chamber has a cylindrical inner diameter and the source of vacuum is a venturi pump connected to a pinch valve permitting overflow of particulate material through the pinch valve and venturi pump, which is returned to the source. In one embodiment, the pinch valve surrounds an open end of the chamber permitting overflow while avoiding agglomeration of the particulate material.
摘要翻译： 一种用于将颗粒材料从源传输到远程位置的泵，包括具有开口端的微粒室，在开口端的止回阀，邻近一端连接到腔室的真空源，在腔室的相对端处的气体源 以及将真空交替地连接到室以将颗粒材料从源抽吸到室并且在压力下连接气体以将颗粒材料驱动到远程位置的控制器。 在优选实施例中，腔室具有圆柱形内径，真空源是连接到夹管阀的文丘里泵，允许颗粒材料通过夹送阀和文丘里泵溢出，该泵返回到源头。 在一个实施例中，夹管阀围绕室的开口端，允许溢流，同时避免颗粒材料的团聚。
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公开(公告)号：US06723145B2
公开(公告)日：2004-04-20
申请号：US10039081
申请日：2002-01-02
申请人： David J. Cole
发明人： David J. Cole
IPC分类号： B01D4600
CPC分类号： B05B14/435 , B05B14/43 , B05B14/48 , Y02P70/36 , Y10S55/46 , Y10S118/07
摘要： An under booth paint collection apparatus is positioned beneath a paint application booth that includes an air circulation system for painting a product with particulate paint. A plurality of discrete powder reclamation collectors are arranged in aligned rows beneath the booth. Continuously aligned air chambers are each positioned above one of the opposing rows of reclamation collectors. Each air chamber is defined by having opposed continuous side walls interconnecting said reclamation collectors. Each air chamber provides a continuous air plenum directing air and particulate paint not adhered to the product being painted from the application booth to the plurality of discrete reclamation chambers.
摘要翻译： 展位涂料收集设备位于涂漆应用室下面，其中包括一个用颗粒涂料喷涂产品的空气循环系统。 多个离散的粉碎回收收集器在展位下排列成排列齐排。 连续排列的空气室各自位于相对的一排回收收集器中的一个上方。 每个空气室由相互连接的连接的侧壁连接所述回收收集器来限定。 每个空气室提供连续的空气通风室，其引导空气和颗粒状涂料不粘附到从涂漆室涂覆到多个离散的回收室的产品。
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公开(公告)号：US6037129A
公开(公告)日：2000-03-14
申请号：US86372
申请日：1998-05-28
申请人： David J. Cole , Paul L. Baron , Paul H. O'Brien
发明人： David J. Cole , Paul L. Baron , Paul H. O'Brien
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/118
摘要： A method of detecting the metastasis of primary breast cancer to a lymph node is provided, comprising detecting, in lymph node tissue, the presence of a nucleic acid of c-myc, PIP or keratin-19. The presence of any one of these nucleic acids in lymph node tissue is associated with metastatic breast cancer. The presence of one or more of these markers in lymph node tissue or other tissue indicates that cells from the primary tumor have migrated from the breast tissue to the lymph node or other tissue. Also provided is a method of predicting the histopathologic stage of a cancer in a patient without having to perform a histopathologic analysis, comprising detecting, in lymph node tissue from the patient, the presence of a nucleic acid of c-myc, the presence of a nucleic acid of c-myc being correlated with stage I cancer as determined by histopathology. Alternatively, the absence of a nucleic acid of PIP and the absence of a nucleic acid of keratin-19 are correlated with stage I cancer as determined by histopathology. In another embodiment, the presence of a nucleic acid of PIP is correlated with stages later than stage I cancer as determined by histopathology. Further, the presence of a nucleic acid of keratin-19 is correlated with stages later than stage I cancer as determined by histopathology. A method of predicting survival time of cancer patients is also provided, comprising detecting, in lymph node tissue from the patient, the presence of a nucleic acid of c-myc, PIP or keratin-19. The presence of a nucleic acid of any of c-myc, PIP or keratin-19 is correlated with a shorter average survival time compared with the presence of none of the nucleic acids.
摘要翻译： 提供了检测原发性乳腺癌转移到淋巴结的方法，包括在淋巴结组织中检测c-myc，PIP或角蛋白-19核酸的存在。 在淋巴结组织中存在这些核酸中的任何一种与转移性乳腺癌相关。 在淋巴结组织或其他组织中存在这些标记物中的一种或多种，表明来自原发性肿瘤的细胞已经从乳腺组织迁移到淋巴结或其他组织。 还提供了一种预测患者癌症组织病理分期的方法，而不必进行组织病理学分析，包括在患者的淋巴结组织中检测c-myc核酸的存在， 通过组织病理学测定，c-myc的核酸与I期癌症相关。 或者，通过组织病理学确定，不存在PIP核酸和不存在角蛋白-19核酸与I期癌症相关。 在另一个实施方案中，通过组织病理学测定，PIP核酸的存在与晚于I期癌症的阶段相关。 此外，通过组织病理学测定，角蛋白-19核酸的存在与晚于I期癌症的阶段相关。 还提供了预测癌症患者生存时间的方法，包括在患者的淋巴结组织中检测c-myc，PIP或角蛋白-19核酸的存在。 与无核酸的存在相比，c-myc，PIP或角蛋白-19中任一种的核酸的存在与较短的平均存活时间相关。
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公开(公告)号：US4984128A
公开(公告)日：1991-01-08
申请号：US330427
申请日：1989-03-30
IPC分类号： G01G7/06
CPC分类号： G01G7/06
摘要： A load sensor which has an elongate hollow body 11, preferably formed as a metal extrusion, and which forms a first capacitative plate 21. A second parallel capacitative plate 15 is formed on an insulating body which is held in place relative to the extrusion by a resilient support 16. Application of a load to the extrusion causes variation in the gap between the plates of the capacitor, thus affecting the capacitance in a manner which is measured and processed to provide an output signal which is directly proportional to the applied load.
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