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公开(公告)号：US20160319363A1
公开(公告)日：2016-11-03
申请号：US14999879
申请日：2016-07-13
Applicant: Rosetta Genomics Ltd.
Inventor： Itzhak Bentwich , Amir Avniel , Yael Karov , Ranit Aharonov
IPC: C12Q1/68
CPC classification number: C12N15/113 , A61K38/00 , C12N15/111 , C12N2310/14 , C12N2310/141 , C12N2310/531 , C12N2320/10 , C12N2320/11 , C12N2320/30 , C12N2330/10 , C12Q1/6809 , C12Q1/6876 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , Y02A90/26
Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.
Abstract translation: 本文描述了与前列腺和肺癌相关的新型多核苷酸。 多核苷酸是miRNA和miRNA前体。 公开了可用于诊断，预后和治疗这些医疗条件的相关方法和组合物。 本文还描述了可用于鉴定前列腺和肺癌调节剂的方法。
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公开(公告)号：US20160046935A1
公开(公告)日：2016-02-18
申请号：US14756185
申请日：2015-08-13
Applicant: Rosetta Genomics Ltd.
Inventor： Itzhak Bentwich , Amir Avniel , Yael Karov , Ranit Aharonov
IPC: C12N15/113 , C12Q1/68
CPC classification number: C12N15/113 , A61K38/00 , C12N15/111 , C12N2310/14 , C12N2310/141 , C12N2310/531 , C12N2320/10 , C12N2320/11 , C12N2320/30 , C12N2330/10 , C12Q1/6809 , C12Q1/6876 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , Y02A90/26
Abstract: Described herein are novel polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.
Abstract translation: 本文描述了与前列腺和肺癌相关的新型多核苷酸。 多核苷酸是miRNA和miRNA前体。 公开了可用于诊断，预后和治疗这些医疗条件的相关方法和组合物。 本文还描述了可用于鉴定前列腺和肺癌调节剂的方法。
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公开(公告)号：US20160002639A1
公开(公告)日：2016-01-07
申请号：US14796112
申请日：2015-07-10
Applicant: Rosetta Genomics Ltd.
Inventor： Issac Bentwich , Amir Avniel , Ranit Aharonov , Yael Karov , Yonat Shemer-Avni , Asaf Levy
IPC: C12N15/113
CPC classification number: C12N15/1133 , A61K48/00 , C12N15/113 , C12N15/1131 , C12N15/1132 , C12N2310/141 , C12N2320/11 , C12N2330/10 , C12N2330/31 , C12N2710/16022 , C12N2760/16122 , C12N2760/18522
Abstract: The invention provides isolated viral and human nucleic acids associated with viral infection and various nucleic acid molecules relating thereto or derived therefrom. The nucleic acids are useful for prevention, treatment and diagnosis of viral infections.
Abstract translation: 本发明提供了与病毒感染相关的分离的病毒和人核酸以及与之相关的或从其衍生的各种核酸分子。 核酸可用于病毒感染的预防，治疗和诊断。
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公开(公告)号：US20190241966A1
公开(公告)日：2019-08-08
申请号：US16226406
申请日：2018-12-19
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald
IPC: C12Q1/6886
CPC classification number: C12Q1/6886 , C12Q2600/158 , C12Q2600/178
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
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公开(公告)号：US09920379B2
公开(公告)日：2018-03-20
申请号：US15586747
申请日：2017-05-04
Applicant: Rosetta Genomics Ltd.
Inventor： Itzhak Bentwich , Amir Avniel , Yael Karov , Ranit Aharonov
IPC: C12N15/11 , C12Q1/68 , A61K38/00 , C12N15/113
CPC classification number: C12N15/113 , A61K38/00 , C12N15/111 , C12N2310/14 , C12N2310/141 , C12N2310/531 , C12N2320/10 , C12N2320/11 , C12N2320/30 , C12N2330/10 , C12Q1/6809 , C12Q1/6876 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , Y02A90/26
Abstract: Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.
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Patent Agency Ranking
公开(公告)号：US09834821B2
公开(公告)日：2017-12-05
申请号：US14592111
申请日：2015-01-08
Applicant: ROSETTA GENOMICS LTD.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Hila Benjamin
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178
Abstract: The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of specific types of cancers. The nucleic acid sequences can also be used for prognosis evaluation of a subject based on the expression pattern of a biological sample.
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公开(公告)号：US09624556B2
公开(公告)日：2017-04-18
申请号：US14797381
申请日：2015-07-13
Applicant: Rosetta Genomics Ltd.
Inventor： Itzhak Bentwich , Amir Avniel , Yael Karov , Ranit Aharonov
CPC classification number: C12Q1/701 , C12N15/111 , C12N15/1131 , C12N2310/14 , C12N2310/141 , C12N2320/10 , C12N2320/30 , C12N2330/10 , C12N2710/16222 , C12Q2600/136
Abstract: Described herein are novel polynucleotides associated with viral infections. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of viral infections.
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公开(公告)号：US09133453B2
公开(公告)日：2015-09-15
申请号：US13986516
申请日：2013-05-08
Applicant: ROSETTA GENOMICS LTD
Inventor： Itzhak Bentwich , Amir Avniel , Yael Karov , Ranit Aharonov
CPC classification number: C12N15/113 , A61K38/00 , C12N15/111 , C12N2310/14 , C12N2310/141 , C12N2310/531 , C12N2320/10 , C12N2320/11 , C12N2320/30 , C12N2330/10 , C12Q1/6809 , C12Q1/6876 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178 , Y02A90/26
Abstract: Described herein are polynucleotides associated with prostate and lung cancer. The polynucleotides are miRNAs and miRNA precursors. Related methods and compositions that can be used for diagnosis, prognosis, and treatment of those medical conditions are disclosed. Also described herein are methods that can be used to identify modulators of prostate and lung cancer.
Abstract translation: 本文描述的是与前列腺和肺癌相关的多核苷酸。 多核苷酸是miRNA和miRNA前体。 公开了可用于诊断，预后和治疗这些医疗条件的相关方法和组合物。 本文还描述了可用于鉴定前列腺和肺癌调节剂的方法。
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公开(公告)号：US20150126399A1
公开(公告)日：2015-05-07
申请号：US14592111
申请日：2015-01-08
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Hila Benjamin
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/158 , C12Q2600/16 , C12Q2600/178
Abstract: The present invention provides nucleic acid sequences that are used for identification, classification and diagnosis of specific types of cancers. The nucleic acid sequences can also be used for prognosis evaluation of a subject based on the expression pattern of a biological sample.
Abstract translation: 本发明提供了用于特定类型癌症的鉴定，分类和诊断的核酸序列。 核酸序列也可以用于基于生物样品的表达模式对受试者的预后评价。
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公开(公告)号：US20190032142A1
公开(公告)日：2019-01-31
申请号：US15909145
申请日：2018-03-01
Applicant: Rosetta Genomics Ltd.
Inventor： Ranit Aharonov , Nitzan Rosenfeld , Shai Rosenwald , Nir Dromi
IPC: C12Q1/6886
Abstract: The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.
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