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    METHOD FOR PREPARING PARA-HYDROXYSTYRENE BY BIOCATALYTIC DECARBOXYLATION OF PARA-HYDROXYCINNAMIC ACID IN A BIPHASIC REACTION MEDIUM
    11.
    发明申请
    METHOD FOR PREPARING PARA-HYDROXYSTYRENE BY BIOCATALYTIC DECARBOXYLATION OF PARA-HYDROXYCINNAMIC ACID IN A BIPHASIC REACTION MEDIUM 审中-公开
    通过生物反应脱羧反应在双相反应介质中制备对羟基苯乙烯的方法

    公开(公告)号：US20080182307A1

    公开(公告)日：2008-07-31

    申请号：US12058986

    申请日：2008-03-31

    申请人： ARIE BEN-BASSAT ,  Sharon L. Haynie ,  David J. Lowe ,  Lisa L. Huang

    发明人： ARIE BEN-BASSAT ,  Sharon L. Haynie ,  David J. Lowe ,  Lisa L. Huang

    IPC分类号： C12P7/22

    CPC分类号： C12P7/22 ,  C12P7/42

    摘要： A biocatalytic method for preparing para-hydroxystyrene from para-hydroxycinnamic acid is described. The method uses an enzyme source having para-hydroxycinnamic acid decarboxylase activity to catalyze the decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium to produce para-hydroxystyrene, which is extracted into the organic phase of the biphasic reaction medium. The method results in a high yield of para-hydroxystyrene due to the decreased exposure of the enzyme source to the inhibitory product. The product is readily recovered from the extractant, or may be chemically derivatized directly in the extractant before recovery.

    摘要翻译： 描述了由对羟基肉桂酸制备对羟基苯乙烯的生物催化方法。 该方法使用具有对羟基肉桂酸脱羧酶活性的酶源来催化双相反应介质中对羟基肉桂酸的脱羧作用，产生对羟基苯乙烯，将其提取到双相反应介质的有机相中。 该方法由于酶源暴露于抑制产物而导致对羟基苯乙烯的高产率。 该产物容易从萃取剂中回收，或者可以在回收之前在萃取剂中直接化学衍生化。

    Product removal process for use in a biofermentation system
    12.
    发明授权
    Product removal process for use in a biofermentation system 失效
    用于生物发酵系统的产品去除过程

    公开(公告)号：US07166460B2

    公开(公告)日：2007-01-23

    申请号：US10860221

    申请日：2004-06-03

    申请人： Antoinette E. Wilkins ,  David J. Lowe

    发明人： Antoinette E. Wilkins ,  David J. Lowe

    IPC分类号： C12M3/00 ,  B01D15/08

    CPC分类号： C12M47/12 ,  B01D15/1814 ,  B01D15/426 ,  C12M29/02 ,  C12M33/14 ,  C12M47/10 ,  C12N1/38 ,  C12P7/18

    摘要： This invention relates to a bioprocess engineering solution for a product removal process for use in a biofermentation. The invention discloses a process for withdrawing an aliquot of broth from a biofermentation vessel during at least a portion of the biofermentation, removing biocatalyst and water, chromatographically separating biofermentation products from the withdrawn broth using water as an eluent, and returning the remaining components of the broth back to the biofermentation vessel. Process chromatography permits highly selective separation of the target molecule, preventing feedback inhibition of the biofermentation.

    摘要翻译： 本发明涉及用于生物发酵的产品去除方法的生物工艺工程解决方案。 本发明公开了一种在至少一部分生物发酵过程中从生物发酵容器中取出等份的肉汤的方法，除去生物催化剂和水，使用水作为洗脱剂，使生物发酵产物与取出的肉汤色谱分离，并返回剩余组分 肉汤回到生物发酵罐。 过程色谱法允许目标分子的高度选择性分离，防止反应抑制生物发酵。

    Method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation
    13.
    发明授权
    Method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation 失效
    使用两相萃取发酵生产对羟基苯乙烯和其他多官能芳族化合物的方法

    公开(公告)号：US07157256B2

    公开(公告)日：2007-01-02

    申请号：US10824237

    申请日：2004-04-14

    申请人： Arie Ben-Bassat ,  David J. Lowe

    发明人： Arie Ben-Bassat ,  David J. Lowe

    IPC分类号： C12P7/22 ,  C12P7/40 ,  C12P7/42

    CPC分类号： C12P7/22 ,  C12P7/28 ,  Y02E50/17

    摘要： Methods are provided for the production and recovery of multifunctional aromatic compounds from a fermentation medium. Preferred multifunctional aromatic compounds include para-hydroxycinnamic acid (pHCA), cinnamic acid (CA), and para-hydroxystyrene (pHS). The multifunctional aromatic compounds may be produced in a biphasic growth medium comprising a fermentation medium having a specified volume of an extractant. The multifunctional aromatic compounds are extracted into the extractant and recovered by standard means.

    摘要翻译： 提供了用于从发酵培养基生产和回收多官能芳族化合物的方法。 优选的多官能芳族化合物包括对羟基肉桂酸（pHCA），肉桂酸（CA）和对羟基苯乙烯（pHS）。 多官能芳族化合物可以在包含具有指定体积的提取剂的发酵培养基的双相生长培养基中生产。 将多官能芳族化合物提取到萃取剂中，并通过标准方法回收。

    Rapid drying of polyamide resins using high frequency electric fields
    14.
    发明授权
    Rapid drying of polyamide resins using high frequency electric fields 失效
    使用高频电场快速干燥聚酰胺树脂

    公开(公告)号：US5237755A

    公开(公告)日：1993-08-24

    申请号：US805148

    申请日：1991-12-11

    申请人： David J. Lowe

    发明人： David J. Lowe

    IPC分类号： B29B13/06 ,  B29B13/08 ,  F26B3/347

    CPC分类号： B29B13/065 ,  F26B3/347

    摘要： A process for quickly drying thermoplastic polyamide resin by the use of a high frequency electric field. The process comprises placing the polyamide between at least two electrodes, applying a high frequency voltage to the electrodes to produce a heating rate of the polyamide between 0.5.degree. C. and 50.degree. C./min, and then removing the water evolved from the polyamide.

    摘要翻译： 一种通过使用高频电场快速干燥热塑性聚酰胺树脂的方法。 该方法包括将聚酰胺放置在至少两个电极之间，向电极施加高频电压以产生0.5℃至50℃/分钟之间聚酰胺的加热速率，然后除去聚酰胺放出的水 。

    Ink jet color graphics printing
    15.
    发明授权
    Ink jet color graphics printing 失效
    喷墨彩色图形打印

    公开(公告)号：US5012257A

    公开(公告)日：1991-04-30

    申请号：US495011

    申请日：1990-03-16

    申请人： David J. Lowe ,  Thomas B. Pritchard

    发明人： David J. Lowe ,  Thomas B. Pritchard

    IPC分类号： B41J2/21 ,  H04N1/23 ,  H04N1/52

    CPC分类号： H04N1/52 ,  B41J2/2132

    摘要： In a color ink jet printing system, an image superpixel (84, 86, 88) consists of a 2 by 2 array of cells (1-4), each cell corresponding to a pixel area on the substrate (80). Each pixel (55) of graphics data is processed to form a 2 by 2 array of bit image data (40), for printing a corresponding superpixel image (68). A superpixel configuration (86), indicating cell location and color of drops of ink for forming a superpixel image, is defined for each desired image color. Superpixel configurations control printing so that drops of ink (Y,M,C) are deposited only an a diagonally adjacent pair of cells (1,4), with no more than two drops of ink per cell, and no more than three drops of ink per superpixel. This superpixel strategy provides for printed images (62,64) perceivable as having the desired image color and having good color saturation, while minimizing bleed across color field boundaries (66).

    摘要翻译： 在彩色喷墨打印系统中，图像超像素（84,86,88）由2×2的单元阵列（1-4）组成，每个单元对应于基板（80）上的像素区域。 图形数据的每个像素（55）被处理以形成2×2的位图数据阵列（40），用于打印对应的超像素图像（68）。 为每个期望的图像颜色定义指示单元格位置和用于形成超像素图像的墨的墨滴的颜色的超像素配置（86）。 超像素配置控制打印，使得墨滴（Y，M，C）仅沉积在对角相邻的一对单元（1,4）上，每个单元不超过两滴墨水，并且不超过三滴 每个超级像素的墨水。 该超像素策略提供可感知为具有所需图像颜色并且具有良好色彩饱和度的打印图像（62,64），同时最小化穿过色域边界（66）的渗色。

    Chart recorders
    16.
    发明授权
    Chart recorders 失效
    图表记录器

    公开(公告)号：US4215351A

    公开(公告)日：1980-07-29

    申请号：US944559

    申请日：1978-09-21

    申请人： David J. Lowe

    发明人： David J. Lowe

    IPC分类号： G01D9/14 ,  G01R19/12 ,  G01D15/24 ,  G01D9/00 ,  G01D15/16

    CPC分类号： G01D9/14 ,  G01R19/12

    摘要： In a potentiometric chart recorder, the speed of the chart motor 22 is, in one mode of operation (AUTO) selected by a switch 32, varied between two values in dependence upon the rate of change or slope of the input signal at 10 as detected in a detector 30. The slow speed is obtained by intermittent operation at the fast speed, and during the non-operative periods power-consuming circuitry e.g. 16, 18, 26 is switched off by a switch 40.

    摘要翻译： 在电位计图表记录器中，在由开关32选择的一种操作模式（AUTO）中，图表电机22的速度在两个值之间根据检测到的输入信号在10处的变化率或斜率而变化 在检测器30中。慢速通过以快速的间歇操作获得，并且在非操作时段期间功耗电路例如 16,18,26由开关40断开。