公开(公告)号：US11136565B2

公开(公告)日：2021-10-05

申请号：US16568089

申请日：2019-09-11

Applicant: Singular Genomics Systems, Inc.

Inventor： Souad Naji ,  Carl W. Fuller ,  Eli Glezer ,  Andrew Spaventa

IPC: C12N9/12 ,  C12P19/34

Abstract: Provided herein are modified Archaeal family B polymerases derived from the Archaeal microorganism Pyrococcus abyssi that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.

公开(公告)号：US20190077726A1

公开(公告)日：2019-03-14

申请号：US16130783

申请日：2018-09-13

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Andrew Spaventa

IPC: C07B59/00 ,  C07H19/02 ,  C07H23/00 ,  C07H1/00 ,  C07H21/00

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of synthesizing labeled nucleosides.