公开(公告)号：US20250084120A1

公开(公告)日：2025-03-13

申请号：US18948143

申请日：2024-11-14

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Andrew Spaventa ,  Eli N. Glezer

IPC: C07H21/04 ,  C12Q1/6869

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing a nucleic acid.

公开(公告)号：US20240410892A1

公开(公告)日：2024-12-12

申请号：US18679036

申请日：2024-05-30

Applicant: Singular Genomics Systems, Inc.

Inventor： Michael Krause ,  Ronald Graham

IPC: G01N33/58 ,  C07D471/04 ,  C09B23/10 ,  C09K11/06

Abstract: Disclosed herein, inter alia, are detectable compounds including a triplet state quencher and the method of use thereof.

公开(公告)号：US20240327907A1

公开(公告)日：2024-10-03

申请号：US18439062

申请日：2024-02-12

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Megha Cila

IPC: C12Q1/6874 ,  C07H19/10 ,  C07H19/20 ,  C12Q1/6806 ,  C12Q1/6876

CPC classification number: C12Q1/6874 ,  C07H19/10 ,  C07H19/20 ,  C12Q1/6876 ,  C12Q1/6806

Abstract: Disclosed herein, inter alia, are methods and cleavable compounds that minimize byproduct formation following cleavage.

公开(公告)号：US11970735B2

公开(公告)日：2024-04-30

申请号：US17417332

申请日：2020-01-07

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Olga Adelfinskaya ,  Megha Cila ,  Rodrigo Rodriguez

IPC: C12Q1/6869 ,  C07F9/655 ,  C07H19/06 ,  C07H19/10 ,  C07H19/14 ,  C07H19/16 ,  C07H19/20 ,  C12N9/12 ,  C12Q1/6806

CPC classification number: C12Q1/6869 ,  C07F9/65515 ,  C07H19/06 ,  C07H19/10 ,  C07H19/14 ,  C07H19/16 ,  C07H19/20 ,  C12N9/1241 ,  C12Q1/6806 ,  C12Q2334/40 ,  C12Q2521/101 ,  C12Q2525/101 ,  C12Q2535/00

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.

公开(公告)号：US20230203083A1

公开(公告)日：2023-06-29

申请号：US18178802

申请日：2023-03-06

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Olga Adelfinskaya ,  Megha Cila ,  Rodrigo Rodriguez ,  Abrehet Abdu ,  Eli N. Glezer

IPC: C07H19/14 ,  C07H19/10 ,  C12Q1/6869 ,  C07H19/20 ,  C12Q1/6876

CPC classification number: C07H19/14 ,  C07H19/10 ,  C12Q1/6869 ,  C07H19/20 ,  C12Q1/6876

Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.

公开(公告)号：US11174281B1

公开(公告)日：2021-11-16

申请号：US17238922

申请日：2021-04-23

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Surya Adhikari ,  Rodrigo Rodriguez ,  Zachary Terranova

IPC: C07H19/10 ,  C07H19/14 ,  C12N9/12 ,  C12Q1/6869

Abstract: Disclosed herein, inter alia, are compounds, modified nucleotides, compositions, and methods of using the same.

公开(公告)号：US20200340051A1

公开(公告)日：2020-10-29

申请号：US16736493

申请日：2020-01-07

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Olga Adelfinskaya ,  Megha Cila ,  Rodrigo Rodriguez

IPC: C12Q1/6869 ,  C12Q1/6806 ,  C07F9/655

Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.

公开(公告)号：US20240400602A1

公开(公告)日：2024-12-05

申请号：US18791082

申请日：2024-07-31

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Olga Adelfinskaya ,  Megha Cila ,  Rodrigo Rodriguez ,  Abrehet Abdu ,  Eli N. Glezer

IPC: C07H19/14 ,  C07H19/10 ,  C07H19/20 ,  C12Q1/6869 ,  C12Q1/6876

Abstract: Disclosed herein, inter alia, are compounds and methods of using the same for the modifying a nucleic acid molecule.

公开(公告)号：US20240368202A1

公开(公告)日：2024-11-07

申请号：US18752325

申请日：2024-06-24

Applicant: Singular Genomics Systems, Inc.

Inventor： Ronald Graham ,  Zachary Terranova

IPC: C07F9/6521

Abstract: Disclosed herein, inter alia, are reducing agents and methods of use thereof.

公开(公告)号：US20240294764A1

公开(公告)日：2024-09-05

申请号：US18435635

申请日：2024-02-07

Applicant: Singular Genomics Systems, Inc.

Inventor： Ada Tong ,  Megha Cila ,  Ronald Graham

IPC: C09B11/24 ,  A61K49/00 ,  C07H19/20 ,  C12Q1/6869

CPC classification number: C09B11/24 ,  A61K49/0041 ,  A61K49/0054 ,  C07H19/20 ,  C12Q1/6869

Abstract: Disclosed herein, inter alia, are fluorescent compounds and methods of making and using thereof.