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公开(公告)号：US20180272040A1
公开(公告)日：2018-09-27
申请号：US15994263
申请日：2018-05-31
Applicant: Surmodics, Inc.
Inventor： Ralph A. Chappa , Andrew G. Bach
CPC classification number: A61L29/085 , A61L29/16 , A61L2300/416 , A61L2300/60
Abstract: Embodiments of the invention include bioactive agent eluting devices. In an embodiment the invention includes a bioactive agent delivery device including a substrate, a hydrophilic polymer disposed on the substrate, and a substantially amorphous bioactive agent disposed on the surface of the hydrophilic polymer. In an embodiment, the invention includes a method of making a bioactive agent delivery device including depositing a hydrophilic polymer on a substrate forming a hydrophilic surface and depositing a substantially amorphous bioactive agent on the hydrophilic surface. In an embodiment, the invention includes a bioactive agent-eluting catheter including a catheter shaft and an expandable balloon disposed on the catheter shaft. Other embodiments are included herein.
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公开(公告)号：US09895516B2
公开(公告)日：2018-02-20
申请号：US15227458
申请日：2016-08-03
Applicant: Surmodics, Inc.
Inventor： James Howard Arps , Andrew G. Bach
CPC classification number: A61M25/1002 , A61K31/337 , A61L29/041 , A61L29/085 , A61L29/145 , A61L29/148 , A61L29/16 , A61L2300/416 , A61L2300/604 , A61L2300/606 , A61L2300/622 , A61M25/104 , A61M2025/1004 , A61M2025/105 , C08L3/02
Abstract: The present invention provides insertable medical devices having elastic surfaces associated with bioactive agent-containing microparticulates and a coating material. Upon expansion of the elastic surfaces the microparticulates can be released to a subject.
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13.发明申请INSERTABLE MEDICAL DEVICES HAVING MICROPARTICULATE-ASSOCIATED ELASTIC SUBSTRATES AND METHODS FOR DRUG DELIVERY 有权具有微晶相关弹性基材的绝缘医疗器械及药物输送方法公开(公告)号：US20160339214A1
公开(公告)日：2016-11-24
申请号：US15227458
申请日：2016-08-03
Applicant: Surmodics, Inc.
Inventor： James Howard Arps , Andrew G. Bach
CPC classification number: A61M25/1002 , A61K31/337 , A61L29/041 , A61L29/085 , A61L29/145 , A61L29/148 , A61L29/16 , A61L2300/416 , A61L2300/604 , A61L2300/606 , A61L2300/622 , A61M25/104 , A61M2025/1004 , A61M2025/105 , C08L3/02
Abstract: The present invention provides insertable medical devices having elastic surfaces associated with bioactive agent-containing microparticulates and a coating material. Upon expansion of the elastic surfaces the microparticulates can be released to a subject.
Abstract translation: 本发明提供具有与含有生物活性剂的微粒和涂层材料相关联的弹性表面的可插入医疗装置。 弹性表面膨胀时，微粒可以释放到受试者身上。
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公开(公告)号：US20160256668A1
公开(公告)日：2016-09-08
申请号：US15061234
申请日：2016-03-04
Applicant: SurModics, Inc.
Inventor： Ralph A. Chappa , Andrew G. Bach , Mark MacGregor
IPC: A61M25/10
CPC classification number: A61M25/1029 , A61L29/08 , A61M25/1027 , A61M2025/1031 , A61M2025/105 , B05B13/0442
Abstract: Embodiments of the invention include apparatus and methods for coating drug eluting medical devices. In an embodiment, the invention includes a coating apparatus including a coating application unit comprising a movement restriction structure; a fluid applicator; and an air nozzle. The apparatus can further include a rotation mechanism and an axial motion mechanism, the axial motion mechanism configured to cause movement of at least one of the coating application unit and the rotation mechanism with respect to one another. Other embodiments are also included herein.
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公开(公告)号：US20140328998A1
公开(公告)日：2014-11-06
申请号：US14272204
申请日：2014-05-07
Applicant: SurModics, Inc.
Inventor： Ralph A. Chappa , Andrew G. Bach , Mark MacGregor
IPC: A61M25/10
CPC classification number: A61M25/1029 , A61M2025/1031 , B05B13/0442
Abstract: Embodiments of the invention include apparatus and methods for coating drug eluting medical devices. In an embodiment, the invention includes a coating apparatus including a coating application unit comprising a movement restriction structure; a fluid applicator; and an air nozzle. The apparatus can further include a rotation mechanism and an axial motion mechanism, the axial motion mechanism configured to cause movement of at least one of the coating application unit and the rotation mechanism with respect to one another. Other embodiments are also included herein.
Abstract translation: 本发明的实施方案包括用于涂敷药物洗脱医学装置的装置和方法。 在一个实施例中，本发明包括涂覆装置，其包括包括运动限制结构的涂布施加单元; 流体施加器; 和空气喷嘴。 该装置还可包括旋转机构和轴向运动机构，所述轴向运动机构构造成使涂层施加单元和旋转机构中的至少一个相对于彼此移动。 本文还包括其它实施例。
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Patent Agency Ranking
公开(公告)号：US11576774B2
公开(公告)日：2023-02-14
申请号：US16914950
申请日：2020-06-29
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US11027049B2
公开(公告)日：2021-06-08
申请号：US15994263
申请日：2018-05-31
Applicant: Surmodics, Inc.
Inventor： Ralph A. Chappa , Andrew G. Bach
Abstract: Embodiments of the invention include bioactive agent eluting devices. In an embodiment the invention includes a bioactive agent delivery device including a substrate, a hydrophilic polymer disposed on the substrate, and a substantially amorphous bioactive agent disposed on the surface of the hydrophilic polymer. In an embodiment, the invention includes a method of making a bioactive agent delivery device including depositing a hydrophilic polymer on a substrate forming a hydrophilic surface and depositing a substantially amorphous bioactive agent on the hydrophilic surface. In an embodiment, the invention includes a bioactive agent-eluting catheter including a catheter shaft and an expandable balloon disposed on the catheter shaft. Other embodiments are included herein.
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公开(公告)号：US20210015613A1
公开(公告)日：2021-01-21
申请号：US16914950
申请日：2020-06-29
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US20180036519A1
公开(公告)日：2018-02-08
申请号：US15783554
申请日：2017-10-13
Applicant: Surmodics, Inc.
Inventor： Ralph A. Chappa , Andrew G. Bach , Mark MacGregor
CPC classification number: A61M25/1029 , A61M2025/1031 , B05B13/0442
Abstract: Embodiments herein include apparatus and methods for coating medical devices. In an embodiment, a coating apparatus is included having a coating application unit including a movement restriction structure, a fluid applicator having a lengthwise major axis, a fluid distribution bar having a body angled with respect to the major lengthwise axis of the fluid applicator between 0 and 20 degrees, a rotation mechanism and an axial motion mechanism. The axial motion mechanism configured to cause movement of at least one of the coating application unit and the rotation mechanism with respect to one another. Other embodiments are also included herein.
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公开(公告)号：US20170367824A1
公开(公告)日：2017-12-28
申请号：US15543704
申请日：2016-01-14
Applicant: SURMODICS, INC.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
CPC classification number: A61F2/2433 , A61M25/0102 , A61M25/0668 , A61M25/09041 , A61M25/10 , A61M2025/0681 , A61M2025/1081
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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