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公开(公告)号:US10695174B2
公开(公告)日:2020-06-30
申请号:US15543704
申请日:2016-01-14
Applicant: SURMODICS, INC.
Inventor: Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号:US11123459B2
公开(公告)日:2021-09-21
申请号:US15842110
申请日:2017-12-14
Applicant: Surmodics, Inc.
Inventor: Joram Slager , Rick Murphy
Abstract: Drug delivery coatings and devices including the same are described herein. The drug delivery coating has a first coated layer with non-ionic polymer and photogroups, a second coated layer with acid polymer in contact and hydrogen bonded with the first layer, particles with hydrophobic therapeutic agent, and cationic agent. The coating can be provided on a balloon catheter, and the particles and cationic agent can be transferred to tissue during a medical procedure, such as an angioplasty procedure, for a therapeutic effect.
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公开(公告)号:US10918835B2
公开(公告)日:2021-02-16
申请号:US15467530
申请日:2017-03-23
Applicant: Surmodics, Inc.
Inventor: Rick Murphy
IPC: A61M25/01 , A61L29/08 , A61M25/10 , A61L29/04 , A61L29/06 , A61L29/14 , A61L29/16 , A61L29/18 , A61M25/06 , A61M25/00
Abstract: Embodiments herein include delivery systems for active agent coated balloons and related methods. In an embodiment, a delivery system can include a tunneling sheath and a balloon catheter. The tunneling sheath can include a tubular shaft having an outer diameter and defining a lumen. The tunneling sheath can include a proximal collar defining a lumen. The balloon catheter can include a balloon catheter shaft disposed within the tubular shaft. The balloon catheter shaft can include a lumen for the passage of a fluid therein. The balloon catheter can include an expandable balloon disposed on the balloon catheter shaft. The balloon catheter shaft can include an active agent layer disposed on the expandable balloon. The position of the expandable balloon can be configured to be stationary relative to the tubular shaft as the delivery system is passed through a blood vessel of a patient. Other embodiments are also included herein.
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公开(公告)号:US11576774B2
公开(公告)日:2023-02-14
申请号:US16914950
申请日:2020-06-29
Applicant: Surmodics, Inc.
Inventor: Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号:US20210015613A1
公开(公告)日:2021-01-21
申请号:US16914950
申请日:2020-06-29
Applicant: Surmodics, Inc.
Inventor: Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号:US20180169305A1
公开(公告)日:2018-06-21
申请号:US15842110
申请日:2017-12-14
Applicant: Surmodics, Inc.
Inventor: Joram Slager , Rick Murphy
Abstract: Drug delivery coatings and devices including the same are described herein. The drug delivery coating has a first coated layer with non-ionic polymer and photogroups, a second coated layer with acid polymer in contact and hydrogen bonded with the first layer, particles with hydrophobic therapeutic agent, and cationic agent. The coating can be provided on a balloon catheter, and the particles and cationic agent can be transferred to tissue during a medical procedure, such as an angioplasty procedure, for a therapeutic effect.
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公开(公告)号:US20170367824A1
公开(公告)日:2017-12-28
申请号:US15543704
申请日:2016-01-14
Applicant: SURMODICS, INC.
Inventor: Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
CPC classification number: A61F2/2433 , A61M25/0102 , A61M25/0668 , A61M25/09041 , A61M25/10 , A61M2025/0681 , A61M2025/1081
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号:US20170281913A1
公开(公告)日:2017-10-05
申请号:US15467530
申请日:2017-03-23
Applicant: Surmodics, Inc.
Inventor: Rick Murphy
CPC classification number: A61M25/10 , A61L29/041 , A61L29/049 , A61L29/06 , A61L29/08 , A61L29/085 , A61L29/14 , A61L29/16 , A61L29/18 , A61L2300/416 , A61L2400/10 , A61M25/007 , A61M25/0194 , A61M2025/0681 , A61M2025/105 , A61M2025/1075 , A61M2025/1079 , A61M2025/1081 , A61M2025/1088 , A61M2025/1093 , C08L27/18 , C08L77/00
Abstract: Embodiments herein include delivery systems for active agent coated balloons and related methods. In an embodiment, a delivery system can include a tunneling sheath and a balloon catheter. The tunneling sheath can include a tubular shaft having an outer diameter and defining a lumen. The tunneling sheath can include a proximal collar defining a lumen. The balloon catheter can include a balloon catheter shaft disposed within the tubular shaft. The balloon catheter shaft can include a lumen for the passage of a fluid therein. The balloon catheter can include an expandable balloon disposed on the balloon catheter shaft. The balloon catheter shaft can include an active agent layer disposed on the expandable balloon. The position of the expandable balloon can be configured to be stationary relative to the tubular shaft as the delivery system is passed through a blood vessel of a patient. Other embodiments are also included herein.
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