公开(公告)号：US08671700B2

公开(公告)日：2014-03-18

申请号：US12690866

申请日：2010-01-20

申请人： Thach Duong ,  Jay J. Eum

发明人： Thach Duong ,  Jay J. Eum

IPC分类号： F04B53/12 ,  F04B15/08

CPC分类号： F04B37/08 ,  F04B15/08 ,  F04B53/1012

摘要： The cryogenic fluid generator includes at least one pump assembly having an actuator mounted to a container assembly. A pump assembly housing includes a longitudinal positioning opening and a pressurization cavity at a distal end terminating with a pump assembly outlet. An internal check valve assembly includes a shaft positioned within an opening of the pump assembly housing that extends into the pressurization cavity. The shaft is attached to the actuator and includes a longitudinal guidance slot; a fluid passageway; and, an internal sealing surface. A positioning bar assembly is positioned within the guidance slot. A connecting rod is securely connected at a first end to the positioning bar assembly, the connecting rod being positioned within the fluid passageway and terminating with a flow inhibiting element. A seal is positioned between the pump assembly housing and the check valve to provide a closure for the pressurization cavity.

摘要翻译： 低温流体发生器包括至少一个具有安装到容器组件的致动器的泵组件。 泵组件壳体包括纵向定位开口和在终端具有泵组件出口的远端处的加压腔。 内部止回阀组件包括位于泵组件壳体的开口内延伸进入加压腔的轴。 轴连接到致动器并且包括纵向引导槽; 流体通道; 和内密封面。 定位杆组件定位在引导槽内。 连杆在第一端处牢固地连接到定位杆组件，连杆位于流体通道内并且终止于流动抑制元件。 密封件定位在泵组件壳体和止回阀之间，以为加压腔提供封闭件。

公开(公告)号：US20120271292A1

公开(公告)日：2012-10-25

申请号：US13539749

申请日：2012-07-02

申请人： Thach Duong ,  Jay J. Eum

发明人： Thach Duong ,  Jay J. Eum

IPC分类号： A61B18/02

CPC分类号： A61B18/02 ,  A61B2017/00274 ,  A61B2017/0046 ,  A61B2018/00547 ,  A61B2018/0262 ,  A61B2090/3925

摘要： A cryosurgical probe that includes a shaft for providing a heat exchange surface for cryogenic ablation, a housing, an insulation element slideably engaged with the shaft, and an adjustable sliding apparatus. The adjustable sliding apparatus includes a slider assembly attached to the insulation element for slideably guiding the insulation element within the shaft, and an actuation assembly operatively connected to the slider assembly for allowing a user to slide the slider assembly to provide a desired adjustment of the insulation element relative to the shaft.

摘要翻译： 一种冷冻手术探针，其包括用于提供用于低温消融的热交换表面的轴，壳体，可滑动地与所述轴接合的绝缘元件以及可调滑动装置。 可调滑动装置包括附接到绝缘元件的滑块组件，用于可滑动地将绝缘元件引导到轴内;以及致动组件，其可操作地连接到滑块组件，用于允许使用者滑动滑块组件以提供期望的绝缘调节 元件相对于轴。

公开(公告)号：US07909227B2

公开(公告)日：2011-03-22

申请号：US11613054

申请日：2006-12-19

申请人： Thach Duong ,  Jenny C. Liu ,  Jay J. Eum

发明人： Thach Duong ,  Jenny C. Liu ,  Jay J. Eum

IPC分类号： B23K37/04

CPC分类号： A61B18/02 ,  A61B2018/0262 ,  F16L9/18 ,  F16L59/065 ,  F16L59/14

摘要： A vacuum insulation tube assembly which is utilized as a component in a cryosurgical probe. The vacuum insulation tube assembly includes an inner tube; and, an outer tube concentrically positioned about the inner tube. The outer tube is securely soldered at end portions of the inner tube and forms a vacuum space between the inner tube and the outer tube. The vacuum tube assemblies may be conveniently mass produced using a special fixture.

摘要翻译： 一种真空绝热管组件，用作冷冻手术探头中的组件。 真空绝热管组件包括内管; 以及围绕内管同心定位的外管。 外管在内管的端部牢固地焊接，并在内管和外管之间形成真空空间。 真空管组件可以使用特殊的夹具方便地批量生产。

公开(公告)号：US07621889B2

公开(公告)日：2009-11-24

申请号：US11148454

申请日：2005-06-09

申请人： Thach Duong ,  Jay J. Eum ,  Jenny C. Liu

发明人： Thach Duong ,  Jay J. Eum ,  Jenny C. Liu

IPC分类号： A61F7/12

CPC分类号： A61F7/12 ,  A61F7/123 ,  A61F2007/126

摘要： An inlet flow of heat exchange fluid flows from an inflow housing inlet section, and through an inflow housing main section. It then flows through an inlet fluid passageway formed between an inner balloon and a discharge tube. The flow continues around a distal end of the inner balloon, thus becoming an outlet flow of the heat exchange fluid which is directed through an outlet fluid passageway formed between the inner balloon and an outer balloon, then through an outflow housing main section and finally discharged through an outflow housing outlet section. The inner balloon is in a position offset from the central axis of the catheter. The offset relationship enhances the fluid dynamic properties of the catheter. It provides an increased turbulence, which, in turn, maximizes the heat exchange efficiency.

摘要翻译： 热交换流体的入口流从流入壳体入口部分流过流入壳体主体部分。 然后流过形成在内气囊和放电管之间的入口流体通道。 流动继续围绕内球囊的远端，从而变成热交换流体的出口流动，该热交换流体被引导通过形成在内球囊和外球囊之间的出口流体通道，然后通过流出壳体主区段并最终排出 通过流出的外壳出口部分。 内囊处于从导管的中心轴线偏移的位置。 偏移关系增强了导管的流体动力学特性。 它提供了增加的湍流，从而使热交换效率最大化。

公开(公告)号：US06972014B2

公开(公告)日：2005-12-06

申请号：US10336322

申请日：2003-01-04

申请人： Jay J. Eum ,  Thach Duong

发明人： Jay J. Eum ,  Thach Duong

IPC分类号： A61B18/00 ,  A61B18/02 ,  A61B18/04 ,  A61B18/18

CPC分类号： A61B18/02 ,  A61B2018/00041 ,  A61B2018/046

摘要： Various embodiments of open system heat exchange catheters and methods of use are disclosed. The various catheters can be used with various ablative surgical devices. One specific exemplary use is in conjunction with cryosurgical probes involving ablation of the prostate, in which the integrity of the urethra is desired to be maintained. Other uses involve various heating ablative devices. In one embodiment an injection tube assembly is used to provide heat exchange fluid through the urethra to the bladder where it is then expelled via a suprapubic suction tube. In other embodiments a coaxial tube assembly is utilized which defines a passageway for either expelling the bladder fluid or for providing access to an endoscope. In other embodiments a double lumen assembly is utilized that defines a passageway for expelling bladder fluid.

摘要翻译： 公开了开放系统热交换导管和使用方法的各种实施例。 各种导管可以与各种烧蚀手术装置一起使用。 一个具体的示例性用途是结合涉及前列腺消融的冷冻手术探针，其中期望保持尿道的完整性。 其他用途涉及各种加热烧蚀装置。 在一个实施例中，注射管组件用于将热交换流体通过尿道提供给膀胱，然后通过耻骨上吸管将其排出。 在其它实施例中，使用同轴管组件，其限定用于排出膀胱流体或用于提供对内窥镜的通路的通道。 在其他实施例中，利用限定用于排出膀胱流体的通道的双腔组件。

公开(公告)号：US6162231A

公开(公告)日：2000-12-19

申请号：US336974

申请日：1999-06-21

申请人： Paul W. Mikus ,  Jay J. Eum

发明人： Paul W. Mikus ,  Jay J. Eum

IPC分类号： A61F2/82 ,  A61F2/06 ,  A61F2/84 ,  A61M25/00 ,  A61M25/06 ,  A61M25/12 ,  A61M29/00 ,  A61F11/00

CPC分类号： A61M25/0662 ,  A61F2/95 ,  A61F2002/9517 ,  A61M25/0068 ,  A61M25/0668 ,  A61M29/00 ,  A61M2210/166

摘要： Two embodiments for a stent delivery device are disclosed. In the first embodiment, the stent delivery device comprises an outer sheath and an inner tubular member which distally ends in a tongue having an arcuate cross section. In a second embodiment, the stent delivery device further comprises a housing having a lumen extending longitudinally therethrough, the lumen holding the inner tubular member. A guide pin attached to the outer sheath is slidably disposed within the housing wherein the guide pin may be longitudinally displaced with respect to the lumen. In addition, an endoscope mounting plate may be slidably disposed along the housing. Detents may be used to releasably prevent a proximal displacement of the guide pin within the lumen of the housing as well as to releasably prevent the proximal displacement of the endoscope mounting plate with respect to the housing.

摘要翻译： 公开了用于支架输送装置的两个实施例。 在第一实施例中，支架输送装置包括外鞘和内管状构件，其以具有弓形横截面的舌头远端终止。 在第二实施例中，支架输送装置还包括具有纵向延伸通过其延伸的内腔的壳体，所述内腔保持内管状构件。 附接到外护套的引导销可滑动地设置在壳体内，其中引导销可以相对于内腔纵向移位。 此外，内窥镜安装板可以沿壳体可滑动地设置。 可以使用定位器来可释放地防止引导销在壳体的腔内的近端位移，并且可释放地防止内窥镜安装板相对于壳体的近侧位移。

公开(公告)号：US06702846B2

公开(公告)日：2004-03-09

申请号：US10091112

申请日：2002-02-28

申请人： Paul W. Mikus ,  William G. Moseley ,  Jay J. Eum

发明人： Paul W. Mikus ,  William G. Moseley ,  Jay J. Eum

IPC分类号： A61F206

CPC分类号： A61F2/88 ,  A61F2/95 ,  A61F2002/048 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2250/0039 ,  A61M27/008

摘要： A stent system and method for use in the prostate gland. The stent is made of a shape memory alloy such as nitinol, and has a low temperature martensite state, with a martensite transition temperature below body temperature, and a high temperature austenite state, with an austenite transition temperature at or above body temperature, and a memorized shape in the high temperature austenite state which is a helical coil of diameter large enough to hold the prostatic urethra open. The stent is used to heat the prostate and is left in the prostatic urethra while the prostate heals. After the prostate is substantially healed, the stent is cooled to its martensite state and is easily removed from the urethra.

摘要翻译： 用于前列腺的支架系统和方法。 该支架由镍钛诺镍等形状记忆合金制成，具有马氏体转变温度低于体温的低温马氏体状态和奥氏体转变温度在体温以上的高温奥氏体状态， 在高温奥氏体状态下记忆形状，其为直径足够大以容纳前列腺尿道打开的螺旋线圈。 支架用于加热前列腺，并在前列腺治疗时留在前列腺尿道。 在前列腺基本上愈合之后，支架被冷却到其马氏体状态，并且容易地从尿道中移出。

公开(公告)号：US6146378A

公开(公告)日：2000-11-14

申请号：US272889

申请日：1999-03-19

申请人： Paul W. Mikus ,  Jay J. Eum

发明人： Paul W. Mikus ,  Jay J. Eum

IPC分类号： A61B19/00 ,  A61B1/00 ,  A61B17/00 ,  A61B17/32 ,  A61B17/34 ,  A61B17/42 ,  A61B18/02 ,  A61M25/08 ,  A61B18/18

CPC分类号： A61B18/02 ,  A61B2017/00292 ,  A61B2017/4216 ,  A61B2018/0212 ,  A61B2090/034 ,  A61B2090/0463 ,  A61B2090/378

摘要： A placement guide for positioning ablation devices within a human body is disclosed. The placement guide comprise an outer catheter and an inner tubular member disposed within a lumen of the outer catheter. When a stop on the inner tubular member engages a seat on the outer catheter, a distal projection of the inner tubular member extends from the distal end of the outer catheter. While monitoring the position of the inner tubular member through an endoscope inserted in its lumen, a clinician positions the distal projection within a human body for optimal ablation. After securing the outer catheter in position, the inner tubular member is withdrawn and replaced with an ablation device which is inserted distally within the outer catheter lumen until a stop on the ablation device engages the seat on the outer catheter wherein a distal projection of the ablation device extends from the distal end of the outer catheter. Because the distal projection of the inner tubular member has a length substantially identical to that of the inner tubular member, the ablation device may be positioned for optimal ablation.

摘要翻译： 公开了一种用于将消融装置定位在人体内的放置引导件。 放置引导件包括外导管和设置在外导管的内腔内的内管状构件。 当内管状构件上的止动件与外导管上的座接合时，内管状构件的远端突出部从外导管的远端延伸。 在通过插入其管腔中的内窥镜监测内管状构件的位置的同时，临床医生将远侧突出物定位在人体内以进行最佳消融。 在将外导管固定就位之后，内管状构件被取出并且被切除装置替代，该消融装置向远端插入外导管内腔中直到消融装置上的止动件接合外导管上的座，其中消融的远侧突出部 装置从外导管的远端延伸。 因为内部管状构件的远侧突出部具有与内部管状构件的长度基本相同的长度，所以可以定位消融装置以实现最佳消融。

公开(公告)号：US06517569B2

公开(公告)日：2003-02-11

申请号：US09813118

申请日：2001-03-20

申请人： Paul W. Mikus ,  Jay J. Eum ,  Dennis Bui ,  Gregory Kelly

发明人： Paul W. Mikus ,  Jay J. Eum ,  Dennis Bui ,  Gregory Kelly

IPC分类号： A61F206

CPC分类号： A61M25/0662 ,  A61F2/95 ,  A61M25/0068 ,  A61M25/0668 ,  A61M29/00 ,  A61M2210/166

摘要： Two embodiments for a stent delivery catheter are disclosed. In the first embodiment, the stent delivery catheter comprises an outer sheath, a peel-away sheath, and an inner sheath. In the second embodiment, the stent delivery catheter comprises an outer sheath and an inner tubular member which distally ends in a tongue having an arcuate cross section.

摘要翻译： 公开了用于支架输送导管的两个实施例。 在第一实施例中，支架输送导管包括外护套，剥离护套和内护套。 在第二实施例中，支架输送导管包括外鞘和内管状构件，其以具有弓形横截面的舌头向远端终止。

公开(公告)号：US06413269B1

公开(公告)日：2002-07-02

申请号：US09612405

申请日：2000-07-06

申请人： Dennis Bui ,  Jay J. Eum ,  Paul W. Mikus

发明人： Dennis Bui ,  Jay J. Eum ,  Paul W. Mikus

IPC分类号： A61F206

CPC分类号： A61F2/962 ,  A61F2/88 ,  A61F2002/047 ,  A61F2002/9505 ,  A61F2002/9517

摘要： A stent delivery catheter. The catheter includes an inner catheter tube and an outer catheter tube which are rotatable relative to each other. The inner catheter and outer catheter include recesses to receive the ends of the stent, permitting pull wires to engage the stent ends without need to for the pull wires to extend radially beyond the bounds of the catheter or requiring the stent ends to protrude it into the lumen of the inner or outer catheter.

摘要翻译： 支架输送导管。 导管包括可相对于彼此旋转的内导管和外导管。 内导管和外导管包括用于接纳支架端部的凹槽，允许拉线接合支架端部，而不需要拉线径向延伸超过导管的界限，或者要求支架端部将其突出到 内导管或外导管的内腔。