公开(公告)号：US20180216180A1

公开(公告)日：2018-08-02

申请号：US15886661

申请日：2018-02-01

Applicant: SEAGATE TECHNOLOGY LLC

Inventor： Kim Yang LEE ,  David S. KUO ,  Thomas Young CHANG ,  Xiaomin YANG ,  ShuaiGang XIAO ,  Koichi WAGO

IPC: C12Q1/6874 ,  G01N27/447 ,  G01N33/487

CPC classification number: C12Q1/6874 ,  C12Q1/6869 ,  G01N27/44791 ,  G01N33/48721

Abstract: A DNA sequencing device, and related methods, include a nanochannel sized to receive a DNA strand, a first electrode member exposed within the nanochannel, and a second electrode member exposed within the nanochannel and spaced apart from the first electrode to form an electrode gap. The second electrode member has a wedge shaped profile, and the first and second electrode members are operable to detect a change in electronic signal as the DNA strand passes through the electrode gap.

公开(公告)号：US20180216178A1

公开(公告)日：2018-08-02

申请号：US15886511

申请日：2018-02-01

Applicant: SEAGATE TECHNOLOGY LLC

Inventor： Kim Yang LEE ,  Thomas Young CHANG ,  David S. KUO ,  ShuaiGang XIAO ,  Xiaomin YANG ,  Koichi WAGO

IPC: C12Q1/6869 ,  G01N27/327 ,  G01N27/447 ,  B81C1/00

CPC classification number: C12Q1/6869 ,  B01L3/502707 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/0896 ,  B81B2201/032 ,  B81B2201/058 ,  B81B2203/0109 ,  B81C1/00071 ,  G01N27/3278 ,  G01N27/447 ,  G01N27/44791 ,  C12Q2565/607 ,  C12Q2565/629

Abstract: A DNA sequencing device and related methods, wherein the device includes a substrate, a nanochannel formed in the substrate, a first electrode positioned on a first side of the nanochannel, and a second electrode. The second electrode is positioned on a second side of the nanochannel opposite the first electrode, and is spaced apart from the first electrode to form an electrode gap that is exposed in the nanochannel. At least a portion of first electrode is movable relative to the second electrode to decrease a size of the electrode gap.