公开(公告)号：US6120454A

公开(公告)日：2000-09-19

申请号：US17581

申请日：1998-02-03

申请人： Veijo T. Suorsa ,  Niyazi Beyhan

发明人： Veijo T. Suorsa ,  Niyazi Beyhan

IPC分类号： A61B8/12 ,  A61B8/00

CPC分类号： A61B8/4488 ,  A61B8/12

摘要： The present invention provides for catheter systems and methods of their use. In one embodiment, the invention provides a catheter system comprising a catheter body having a distal end, a proximal end and a working lumen. A cable is disposed within the working lumen. A plurality of transducer elements, configured in an annular array, are operably attached to a distal end of the cable.

摘要翻译： 本发明提供导管系统及其使用方法。 在一个实施例中，本发明提供了一种导管系统，其包括具有远端，近端和工作腔的导管本体。 电缆设置在工作腔内。 构造成环形阵列的多个换能器元件可操作地附接到电缆的远端。

公开(公告)号：US20100158795A1

公开(公告)日：2010-06-24

申请号：US12474169

申请日：2009-05-28

申请人： Nikolai Aljuri ,  Niyazi Beyhan

发明人： Nikolai Aljuri ,  Niyazi Beyhan

IPC分类号： A61K33/00 ,  A61K51/00 ,  A61B5/08

CPC分类号： A61B5/0833 ,  A61B5/14542 ,  A61B5/4839 ,  A61M16/04 ,  A61M2016/0413 ,  A61M2025/1052 ,  A61M2210/1039

摘要： Methods and systems for isolating, assessing and treating lung compartments are disclosed. One or more lung compartments are accessed through an isolation catheter, oxygen rich gas is delivered to the compartments, and blood oxygen or exhaled carbon dioxide are monitored to assess lung compartment function. Diseased lung compartments may be treated using therapeutic agents delivered to the diseased compartments through the isolation catheter. Therapeutic agents include carbon monoxide, radioactive agents, chemotherapeutic agents or angiogenesis inhibitors and angiocidal agents.

摘要翻译： 公开了用于分离，评估和治疗肺隔室的方法和系统。 通过隔离导管接近一个或多个肺隔间，将富氧气体输送到隔室，并监测血氧或呼出的二氧化碳以评估肺隔室功能。 可以使用通过隔离导管递送到患病隔室的治疗剂来治疗疾病的肺隔室。 治疗剂包括一氧化碳，放射剂，化学治疗剂或血管生成抑制剂和抗血栓形成剂。

公开(公告)号：US07686816B2

公开(公告)日：2010-03-30

申请号：US11254234

申请日：2005-10-18

申请人： W. Martin Belef ,  John H. Ream ,  Thomas C. Moore ,  Steven N. Roe ,  Jeffrey M. Jones ,  Niyazi Beyhan ,  Arcadi Elbert

发明人： W. Martin Belef ,  John H. Ream ,  Thomas C. Moore ,  Steven N. Roe ,  Jeffrey M. Jones ,  Niyazi Beyhan ,  Arcadi Elbert

IPC分类号： A61M25/01 ,  A61B19/00

CPC分类号： A61B8/12 ,  A61B1/0016 ,  A61B8/4209 ,  A61B8/4461 ,  A61B46/10 ,  A61M25/0113 ,  A61M2025/0008

摘要： The system (2) includes a catheter drive unit (22) and a catheter (24) extending therefrom movably mounted to a catheter drive sled (26). The catheter drive unit rotates and translates the catheter core (34) within the catheter sheath (36). The sled has a serrated, conical drive unit interface (82), with a bag-piercing tip (86) mateable with a translator drive output (92) so that a sterile drape (112) enclosing the catheter drive unit is automatically pierced when the catheter drive unit is mounted to the sled. A control unit (6) is spaced apart from the catheter drive unit and provides power and commands to the catheter drive unit and receives information and data from the catheter drive unit. The rotator and translator drive motors (54, 90) are operated from both the control unit and the catheter drive unit. Both the control unit and catheter drive unit have translation displacement displays (10, 30).

摘要翻译： 系统（2）包括导管驱动单元（22）和从其可移动地安装到导管驱动滑架（26）上的导管（24）。 导管驱动单元旋转并平移导管芯（34）在导管套（36）内。 滑板具有锯齿状的锥形驱动单元接口（82），具有与翻译器驱动输出（92）配合的穿刺尖端（86），使得当包括导管驱动单元的无菌悬垂（112）自动穿透时 导管驱动单元安装在滑轨上。 控制单元（6）与导管驱动单元间隔开，并向导管驱动单元提供电力和命令，并从导管驱动单元接收信息和数据。 旋转器和转换器驱动马达（54,90）从控制单元和导管驱动单元两者操作。 控制单元和导管驱动单元都具有平移位移显示器（10,30）。

公开(公告)号：US20100036361A1

公开(公告)日：2010-02-11

申请号：US12474179

申请日：2009-05-28

申请人： Hoang Nguyen ,  Niyazi Beyhan ,  Son Gia

发明人： Hoang Nguyen ,  Niyazi Beyhan ,  Son Gia

IPC分类号： A61M31/00 ,  A61M5/315

CPC分类号： A61B17/12022 ,  A61B17/12104 ,  A61B17/12131 ,  A61B2090/034 ,  A61M37/0069

摘要： A system for delivering multiple implants into lung passageways is disclosed. The system comprises a catheter configured to receive and store a plurality of expandable implants, and an actuatable delivery tool coupled to the proximal end of the catheter. The system expels an implant of the plurality of implants with each actuation of the delivery tool. The delivery tool comprises a plunger element which extends through the catheter from the proximal to the distal end and allows the delivery tool to mechanically communicate with the implants. In one embodiment, the system comprises a spring-loaded slidable element, and a user compresses the slidable element to actuate the delivery tool. In another embodiment, the system comprises a rotation rod, and the user moves the rotation rod in a distal direction to actuate the delivery tool.

摘要翻译： 公开了一种用于将多个植入物输送到肺通道中的系统。 该系统包括被配置为接收和存储多个可扩展植入物的导管，以及联接到导管的近端的可致动输送工具。 该系统通过递送工具的每次致动来排出多个植入物的植入物。 递送工具包括柱塞元件，该柱塞元件从近端延伸到远端并允许输送工具与植入物机械连通。 在一个实施例中，系统包括弹簧加载的可滑动元件，并且使用者压缩可滑动元件以致动输送工具。 在另一个实施例中，系统包括旋转杆，并且使用者沿远侧方向移动旋转杆以致动输送工具。

公开(公告)号：US06361497B1

公开(公告)日：2002-03-26

申请号：US09611374

申请日：2000-07-07

申请人： Georgi Lathbury ,  Niyazi Beyhan ,  Thomas C. Moore ,  Sharon Liberty

发明人： Georgi Lathbury ,  Niyazi Beyhan ,  Thomas C. Moore ,  Sharon Liberty

IPC分类号： A61B800

CPC分类号： A61B8/467 ,  A61B8/12 ,  A61B8/4405 ,  A61B8/461

摘要： A control panel for an ultrasonic imaging system. A pointing device such as a track ball is centrally located on the control panel and a plurality of buttons and control knobs are arranged around the pointing device in a manner that is ergonomically improved and enhances intuitive system operation. For example, a plurality of image mode selection buttons may be arranged in a substantially linear fashion and located above the pointing device on the control panel. The imaging mode selection buttons preferably are arranged from left to right in order of anticipated use or in order of anticipated frequency of use.

公开(公告)号：US06358207B1

公开(公告)日：2002-03-19

申请号：US09689204

申请日：2000-10-11

申请人： Georgi Lathbury ,  Niyazi Beyhan ,  Thomas C. Moore ,  Sharon Liberty

发明人： Georgi Lathbury ,  Niyazi Beyhan ,  Thomas C. Moore ,  Sharon Liberty

IPC分类号： A61B800

CPC分类号： A61B8/467 ,  A61B8/12 ,  A61B8/4405 ,  A61B8/461

摘要： A control panel for an ultrasonic imaging system. A pointing device such as a track ball is centrally located on the control panel and a plurality of buttons and control knobs are arranged around the pointing device in a manner that is ergonomically improved and enhances intuitive system operation. For example, a plurality of image mode selection buttons may be arranged in a substantially linear fashion and located above the pointing device on the control panel. The imaging mode selection buttons preferably are arranged from left to right in order of anticipated use or in order of anticipated frequency of use.

摘要翻译： 一种用于超声成像系统的控制面板。 诸如轨迹球的指示装置位于控制面板的中央，多个按钮和控制旋钮以符合人体工程学改进的方式设置在指点设备周围，并增强了直观的系统操作。 例如，多个图像模式选择按钮可以以基本线性的方式布置并且位于控制面板上的指示设备上方。 成像模式选择按钮优选地按照预期的使用顺序从左到右按照预期的使用频率顺序排列。

公开(公告)号：US20110152678A1

公开(公告)日：2011-06-23

申请号：US12820547

申请日：2010-06-22

申请人： Nikolai Aljuri ,  Rodney C. Perkins ,  Niyazi Beyhan

发明人： Nikolai Aljuri ,  Rodney C. Perkins ,  Niyazi Beyhan

IPC分类号： A61M16/00 ,  A61B6/03

CPC分类号： A61B17/12104 ,  A61B5/055 ,  A61B5/08 ,  A61B5/0813 ,  A61B5/085 ,  A61B5/6853 ,  A61B6/03 ,  A61B6/032 ,  A61B17/1204 ,  A61B17/12136 ,  A61B2017/00022 ,  A61M16/0434 ,  A61M16/208 ,  A61M25/10 ,  A61M2016/0027 ,  A61M2016/003 ,  A61M2025/1052 ,  A61M2205/3303 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2210/1035 ,  A61M2230/46

摘要： The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.

摘要翻译： 通过在进入肺隔室的气道中密封导管的远端来减少超膨胀的肺隔室的体积。 当患者呼气时，空气通过导管中的通道从肺隔间通过。 与导管相关联的单向流动元件防止空气在患者吸入时再次进入肺隔室。 随着时间的推移，随着空气体积的减小，肺室周围的区域压力会使其崩溃。 残余体积减少有效地导致功能性肺容积扩张。 任选地，肺隔室可以被密封以便永久地防止空气重新进入肺隔室。

公开(公告)号：US20070219446A1

公开(公告)日：2007-09-20

申请号：US11685268

申请日：2007-03-13

申请人： Niyazi Beyhan

发明人： Niyazi Beyhan

IPC分类号： A61B8/00 ,  A61N5/00

CPC分类号： A61B8/4461 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4488 ,  A61N5/1015

摘要： Methods and apparatus for image-guided interstitial radiation are provided. In practicing the subject methods, a catheter is placed in the interstitium in close proximity to the site of tumor. The interstitial catheter is designed to receive an ultrasound imaging probe, and a radioactive source for interstitial radiation therapy. The interstitial catheter may be equipped with a balloon member. Further a system facilitating substance communication with the interstitium is provided.

摘要翻译： 提供了图像引导间质辐射的方法和装置。 在实施主题方法时，将导管放置在靠近肿瘤部位的间质中。 间质导管被设计为接收超声成像探针和用于间质放射治疗的放射源。 间质导管可以配备气囊构件。 此外，还提供了促进与间质的物质通信的系统。

公开(公告)号：US06398755B1

公开(公告)日：2002-06-04

申请号：US09317778

申请日：1999-05-24

申请人： W. Martin Belef ,  John H. Ream ,  Thomas C. Moore ,  Steven N. Roe ,  Jeffrey M. Jones ,  Niyazi Beyhan ,  Arcadi Elbert

发明人： W. Martin Belef ,  John H. Ream ,  Thomas C. Moore ,  Steven N. Roe ,  Jeffrey M. Jones ,  Niyazi Beyhan ,  Arcadi Elbert

IPC分类号： A61M3700

CPC分类号： A61B8/12 ,  A61B1/0016 ,  A61B8/4209 ,  A61B8/4461 ,  A61B46/10 ,  A61M25/0113 ,  A61M2025/0008

摘要： The system (2) includes a catheter drive unit (22) and a catheter (24) extending therefrom movably mounted to a catheter drive sled (26). The catheter drive unit rotates and translates the catheter core (34) within the catheter sheath (36). The sled has a serrated, conical drive unit interface (82), with a bag-piercing tip (86) mateable with a translator drive output (92) so that a sterile drape (112) enclosing the catheter drive unit is automatically pierced when the catheter drive unit is mounted to the sled. A control unit (6) is spaced apart from the catheter drive unit and provides power and commands to the catheter drive unit and receives information and data from the catheter drive unit. The rotator and translator drive motors (54, 90) are operated from both the control unit and the catheter drive unit. Both the control unit and catheter drive unit have translation displacement displays (10, 30).

摘要翻译： 系统（2）包括导管驱动单元（22）和从其可移动地安装到导管驱动滑架（26）上的导管（24）。 导管驱动单元旋转并平移导管芯（34）在导管套（36）内。 滑板具有锯齿状的锥形驱动单元接口（82），具有与翻译器驱动输出（92）配合的穿刺尖端（86），使得当包括导管驱动单元的无菌悬垂（112）自动穿透时 导管驱动单元安装在滑轨上。 控制单元（6）与导管驱动单元间隔开，并向导管驱动单元提供电力和命令，并从导管驱动单元接收信息和数据。 旋转器和转换器驱动马达（54,90）从控制单元和导管驱动单元两者操作。 控制单元和导管驱动单元都具有平移位移显示器（10,30）。

公开(公告)号：US6142940A

公开(公告)日：2000-11-07

申请号：US167055

申请日：1998-10-06

申请人： Georgi Lathbury ,  Niyazi Beyhan ,  Thomas C. Moore ,  Sharon Liberty

发明人： Georgi Lathbury ,  Niyazi Beyhan ,  Thomas C. Moore ,  Sharon Liberty

IPC分类号： A61B8/12 ,  A61B8/00

CPC分类号： A61B8/467 ,  A61B8/12 ,  A61B8/461 ,  A61B8/4405

摘要： A control panel for an ultrasonic imaging system. A pointing device such as a track ball is centrally located on the control panel and a plurality of buttons and control knobs are arranged around the pointing device in a manner that is ergonomically improved and enhances intuitive system operation. For example, a plurality of image mode selection buttons may be arranged in a substantially linear fashion and located above the pointing device on the control panel. The imaging mode selection buttons preferably are arranged from left to right in order of anticipated use or in order of anticipated frequency of use.