公开(公告)号：US20110311649A1

公开(公告)日：2011-12-22

申请号：US12739852

申请日：2008-10-24

申请人： Raphael Dumeunier ,  Clemens Lamberth ,  Stephan Trah ,  Sebastian Volker Wendeborn

发明人： Raphael Dumeunier ,  Clemens Lamberth ,  Stephan Trah ,  Sebastian Volker Wendeborn

IPC分类号： A01N43/40 ,  C07D401/14 ,  A01N43/42 ,  A01N57/00 ,  A01N43/54 ,  A01N43/84 ,  A01N59/20 ,  C07D401/04 ,  A01P3/00

CPC分类号： C07D233/61 ,  C07D233/68 ,  C07D401/04 ,  C07D401/14 ,  C07D409/04 ,  C07D409/14

摘要： The present invention relates to novel imidazole derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is halogen, C1-C4alkyl or C1-C4haloalkyl; R2 is an optionally substituted aryl or heteroaryl; R3 is halogen; R4 is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, hydroxyl, C1-C4alkoxy, OR6, C1-C4haloalkoxy or cyano; R5 is halogen; R6 is hydrogen, C3-C7 cycloalkyl, C3-C10 alkylcycloalkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C3-C7 cycloalkenyl, C2-C6 alkynyl, C2-C6 haloalkynyl or C2-C6 alkyloxyalkyl; X is N or C(R); and R is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; or an agrochemically usable salt form thereof; provided that when X is C(R), R2 cannot be an optionally substituted aryl.

摘要翻译： 本发明涉及式（I）的新咪唑衍生物作为具有杀微生物活性，特别是杀真菌活性的活性成分：其中R1是卤素，C1-C4烷基或C1-C4卤代烷基; R2是任选取代的芳基或杂芳基; R3是卤素; R4是氢，卤素，C1-C4烷基，C1-C4卤代烷基，羟基，C1-C4烷氧基，OR6，C1-C4卤代烷氧基或氰基; R5是卤素; R6是氢，C3-C7环烷基，C3-C10烷基环烷基，C1-C6卤代烷基，C2-C6烯基，C2-C6卤代烯基，C3-C7环烯基，C2-C6炔基，C2-C6卤代炔基或C2-C6烷氧基烷基; X是N或C（R）; 且R为氢，卤素，C 1 -C 4烷基，C 1 -C 4卤代烷基，C 1 -C 4烷氧基，C 1 -C 4卤代烷氧基或氰基; 或其农业化学可用的盐形式; 条件是当X是C（R）时，R 2不能是任选取代的芳基。

公开(公告)号：US20100113457A1

公开(公告)日：2010-05-06

申请号：US12447025

申请日：2007-10-23

申请人： Stephan Trah ,  Clemens Lamberth ,  Sebastian Wendeborn

发明人： Stephan Trah ,  Clemens Lamberth ,  Sebastian Wendeborn

IPC分类号： A01N43/58 ,  C07D237/12 ,  C07D237/14 ,  A01P3/00 ,  A01P1/00

CPC分类号： C07D237/12 ,  A01N43/58 ,  C07D237/14 ,  C07D237/24

摘要： The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is hydrogen, C1-C6alkyl, C1-C6haloalkyl or C3-C6cycloalkyl; R2 is halogen, nitro, cyano, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy, C1-C4alkylthio or C1-C4haloalkylthio; R3 is an optionally substituted aryl; R4 is fluoro, cyano, C1-C6haloalkyl, C3-C6cycloalkyl, C1-C6haloalkoxy, C1-C6alkylthio or C1-C6haloalkylthio; and n is a whole number from 1 to 4; or an agrochemically usable salt form thereof.

摘要翻译： 本发明涉及具有杀微生物活性，特别是杀真菌活性的活性成分的式（I）的新哒嗪衍生物，其中R1是氢，C1-C6烷基，C1-C6卤代烷基或C3-C6环烷基; R 2是卤素，硝基，氰基，C 1 -C 4烷基，C 1 -C 4卤代烷基，C 1 -C 4烷氧基，C 1 -C 4卤代烷氧基，C 1 -C 4烷硫基或C 1 -C 4卤代烷硫基; R3是任选取代的芳基; R 4是氟，氰基，C 1 -C 6卤代烷基，C 3 -C 6环烷基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基或C 1 -C 6卤代烷硫基; n为1〜4的整数; 或其农业化学上可用的盐形式。

公开(公告)号：US08410026B2

公开(公告)日：2013-04-02

申请号：US12863377

申请日：2009-01-14

申请人： Stephan Trah ,  Clemens Lamberth ,  Raphael Dumeunier ,  Sebastian Volker Wendeborn

发明人： Stephan Trah ,  Clemens Lamberth ,  Raphael Dumeunier ,  Sebastian Volker Wendeborn

IPC分类号： A01N43/58 ,  A61K31/50 ,  C07D237/00

CPC分类号： C07D401/04

摘要： The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is methyl, ethyl or isopropyl; R2 is chloro, fluoro, hydroxy or C1-C2alkoxy; R3 is H, chloro, fluoro, methoxy or C1-C3alkyl; R4 is chloro, fluoro or bromo; and R5 is H, fluoro or methoxy; or an agrochemically usable salt form thereof; with the proviso that when R1 is methyl, R2 is chloro and R3 is H, then R4 or R5 is different from fluoro.

摘要翻译： 本发明涉及式（I）的新的哒嗪衍生物作为具有杀微生物活性的活性成分，特别是杀真菌活性：其中R1是甲基，乙基或异丙基; R 2是氯，氟，羟基或C 1 -C 2烷氧基; R3是H，氯，氟，甲氧基或C1-C3烷基; R4是氯，氟或溴; R5为H，氟或甲氧基; 或其农业化学可用的盐形式; 条件是当R 1为甲基时，R 2为氯且R 3为H，则R 4或R 5不同于氟。

公开(公告)号：US20120295876A1

公开(公告)日：2012-11-22

申请号：US13576945

申请日：2011-02-01

申请人： Stephan Trah ,  Clemens Lamberth

发明人： Stephan Trah ,  Clemens Lamberth

IPC分类号： A01N43/58 ,  C07D237/12 ,  A01P3/00 ,  A01N43/90 ,  A01N57/00 ,  C07D237/14 ,  A01N43/84

CPC分类号： C07D237/12 ,  A01N43/58 ,  C07D237/14 ,  C07D307/58 ,  C07D307/60

摘要： The present invention relates to novel pyridazine derivatives of formula (I) wherein R1 is methyl or ethyl; R2 is H or chloro; R3 is fluoro or chloro; R4 is fluoro or methoxy; and R5 is chloro or methoxy or an agrochemically usable salt from thereof, as active ingredients which have microbiodidal activity, in particular fungicidal activity.

摘要翻译： 本发明涉及式（I）的新的哒嗪衍生物，其中R 1是甲基或乙基; R2是H或氯; R3是氟或氯; R4是氟或甲氧基; R5为氯或甲氧基或其农药可用盐，作为具有微生物活性的活性成分，特别是杀真菌活性。

公开(公告)号：US20120010195A1

公开(公告)日：2012-01-12

申请号：US13256074

申请日：2010-02-08

申请人： Raphael Dumeunier ,  Clemens Lamberth ,  Stephan Trah

发明人： Raphael Dumeunier ,  Clemens Lamberth ,  Stephan Trah

IPC分类号： A01N43/46 ,  A01P3/00 ,  C07D403/04

CPC分类号： C07D233/88

摘要： The present invention relates to novel imidazole derivatives of formula (I) having microbiocidal, in particular fungicidal, activity, to processes for their preparation and intermediates used in their preparation, to agrochemical compositions comprising them and to the use in agriculture or horticulture for controlling or preventing infestation of plants, harvested food crops, seeds or non-living materials by phytopathogenic microorganisms, preferably fungi.

摘要翻译： 本发明涉及式（I）的新型咪唑衍生物，其具有杀微生物，特别是杀真菌活性，其制备方法和用于其制备的中间体，包含它们的农用化学组合物以及在农业或园艺中用于控制或 通过植物病原微生物，优选真菌预防植物，收获的食物作物，种子或非生物材料的侵染。

公开(公告)号：US20110224252A1

公开(公告)日：2011-09-15

申请号：US12739863

申请日：2008-10-24

申请人： Raphael Dumeunier ,  Clemens Lamberth ,  Stephan Trah ,  Sebastian Wendeborn

发明人： Raphael Dumeunier ,  Clemens Lamberth ,  Stephan Trah ,  Sebastian Wendeborn

IPC分类号： A01N43/42 ,  C07D233/68 ,  A01N43/50 ,  C07D401/04 ,  A01N43/40 ,  C07D409/04 ,  C07D401/02 ,  A01P3/00

CPC分类号： C07D401/04 ,  A01N43/50 ,  C07D233/28 ,  C07D401/14 ,  C07D409/14

摘要： The present invention relates to novel imidazole derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is halogen, C1-C4alkyl or C1-C4haloalkyl; R2 is an optionally substituted aryl or heteroaryl; R3 is halogen; R4 is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; R5 is halogen; X is N or C(R); and R is hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy or cyano; or an agrochemically usable salt form thereof; provided that when X is C(R), R2 cannot be an optionally substituted aryl.

摘要翻译： 本发明涉及式（I）的新咪唑衍生物作为具有杀微生物活性，特别是杀真菌活性的活性成分：其中R1是卤素，C1-C4烷基或C1-C4卤代烷基; R2是任选取代的芳基或杂芳基; R3是卤素; R4是氢，卤素，C1-C4烷基，C1-C4卤代烷基，C1-C4烷氧基，C1-C4卤代烷氧基或氰基; R5是卤素; X是N或C（R）; 且R为氢，卤素，C 1 -C 4烷基，C 1 -C 4卤代烷基，C 1 -C 4烷氧基，C 1 -C 4卤代烷氧基或氰基; 或其农业化学可用的盐形式; 条件是当X是C（R）时，R 2不能是任选取代的芳基。

公开(公告)号：US20100113464A1

公开(公告)日：2010-05-06

申请号：US12373906

申请日：2007-07-16

申请人： Stephan Trah ,  Clemens Lamberth ,  Sebastian Volker Wendeborn

发明人： Stephan Trah ,  Clemens Lamberth ,  Sebastian Volker Wendeborn

IPC分类号： A61K31/50 ,  C07D401/04 ,  C07D405/04 ,  C07D409/04

CPC分类号： C07D401/04 ,  A01N43/58 ,  A01N43/60 ,  A01N43/78 ,  A01N43/80 ,  A01N43/82 ,  C07D403/04 ,  C07D405/04 ,  C07D407/04 ,  C07D409/04 ,  C07D413/04 ,  C07D417/04

摘要： The present invention relates to novel pyridazine derivatives of formula I as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is hydrogen, C1-C6alkyl, C1-C6haloalkyl or C3-C6cycloalkyl; R2 is an optionally substituted heteroaryl; R3 is an optionally substituted aryl; and R4 is hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy, (VCehaloalkoxy, hydroxy or cyano; or an agrochemically usable salt form thereof.

摘要翻译： 本发明涉及式I的新的哒嗪衍生物作为具有杀微生物活性，特别是杀真菌活性的活性成分，其中R1是氢，C1-C6烷基，C1-C6卤代烷基或C3-C6环烷基; R2是任选取代的杂芳基; R3是任选取代的芳基; 和R 4是氢，卤素，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 1 -C 6烷氧基，（C 5卤代烷氧基，羟基或氰基）或其农业上可用的盐形式。

公开(公告)号：US20100022526A1

公开(公告)日：2010-01-28

申请号：US12524096

申请日：2008-01-21

申请人： Clemens Lamberth ,  Sebastian Volker Wendeborn ,  Stephan Trah ,  Raphael Dumeunier

发明人： Clemens Lamberth ,  Sebastian Volker Wendeborn ,  Stephan Trah ,  Raphael Dumeunier

IPC分类号： A01N43/58 ,  C07D237/02 ,  A01N43/84 ,  A01P3/00

CPC分类号： C07D237/12 ,  A01N43/58 ,  C07D237/14 ,  C07D237/16 ,  C07D237/24 ,  C07D401/04 ,  C07D403/04 ,  C07D405/04 ,  C07D409/04

摘要： The present invention relates to compounds of formula (I) wherein R1, R2, R3 and R4 are as defined in claim 1, which are useful as fungicides.

摘要翻译： 本发明涉及式（I）化合物，其中R 1，R 2，R 3和R 4如权利要求1中所定义，其可用作杀真菌剂。

公开(公告)号：US20100016339A1

公开(公告)日：2010-01-21

申请号：US12375839

申请日：2007-07-30

申请人： Jeremy Godwin ,  Stephan Trah ,  Clemens Lamberth ,  Sebastian Volker Wendeborn

发明人： Jeremy Godwin ,  Stephan Trah ,  Clemens Lamberth ,  Sebastian Volker Wendeborn

IPC分类号： A01N43/90 ,  C07D237/02 ,  A01N43/58 ,  A01P3/00

CPC分类号： C07D237/12 ,  A01N43/58

摘要： The present invention relates, inter alia, to a compound having the formula (I):—wherein (R)n is selected from the group consisting of 4-Br, 4-OCH2CH3, 4-OCH2CF3, 2-CH3-4-Cl, 2-CH3-4-OCH3, 2-CH3-4-OCF3, 2-F-4-Br, 2-F-4-CF3, 3-CH3-4-Br, 3-F-4-Cl, 3-F-4-CH3, 3-F-4-Br, 3-F-4-OCH3 and 3-F-4-F. The present invention further relates to a fungicidal composition comprising a compound having the formula (I)—and also to fungicidal compositions comprising compounds having the formula (II) and/or (III): Furthermore, the present invention relates to methods for controlling pathogenic organisms using the compositions.

摘要翻译： 本发明特别涉及具有式（I）的化合物：其中（R）n选自4-Br，4-OCH2CH3,4-OCH2CF3,2-CH3-4-Cl ，2-CH3-4-OCH3,2-CH3-4-OCF3,2-F-4-Br，2-F-4-CF3,3-CH3-4-Br，3-F-4-Cl，3 -F-4-CH 3，3-F-4-Br，3-F-4-OCH 3和3-F-4-F。 本发明还涉及包含具有式（I）的化合物的杀真菌组合物，还涉及包含具有式（II）和/或（III）的化合物的杀真菌组合物：此外，本发明涉及控制致病性的方法 使用组合物的生物体。

公开(公告)号：US20090298898A1

公开(公告)日：2009-12-03

申请号：US12533302

申请日：2009-07-31

申请人： Werner Zambach ,  Roger Graham Hall ,  Peter Renold ,  Stephan Trah

发明人： Werner Zambach ,  Roger Graham Hall ,  Peter Renold ,  Stephan Trah

IPC分类号： A01N43/80 ,  C07C233/02 ,  C07C249/02 ,  C07D261/06 ,  A01N37/18 ,  A01N33/02 ,  A01P7/00

CPC分类号： C07D333/58 ,  A01N33/24 ,  A01N35/10 ,  A01N37/52 ,  A01N41/06 ,  A01N43/10 ,  A01N43/40 ,  A01N43/78 ,  A01N43/80 ,  C07C49/753 ,  C07C49/755 ,  C07C49/84 ,  C07C235/84 ,  C07C251/44 ,  C07C251/48 ,  C07C251/54 ,  C07C251/58 ,  C07C311/04 ,  C07C311/05 ,  C07C311/09 ,  C07C323/47 ,  C07D213/50 ,  C07D213/53 ,  C07D213/61 ,  C07D213/64 ,  C07D261/08 ,  C07D277/24 ,  C07D277/28 ,  C07D307/52 ,  C07D307/81 ,  C07D333/22

摘要： Compounds of formula wherein A0, A1 and A2 are each independently of the others a bond or a C1-C6alkylene bridge; A3 is a C1-C6alkylene bridge which is unsubstituted or substituted by from one to six identical or different substituents selected from halogen and C3-C8cycloalkyl; Y is, for example, O, S, SO or SO2; M is O or NOR6, X1 and X2 are each independently of the other fluorine, chlorine or bromine; R1, R2 and R3 are, for example, H, halogen, OH, SH, CN, nitro, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkylcarbonyl, C2-C6alkenyl, C2-C6haloalkenyl or C2-C6alkynyl; Q is, for example, O, S, SO or SO2; W is, for example, O, S, SO, SO2, —C(═O)—O— or —O—C(═O)—; T is, for example, a bond, O, S, SO, SO2, —C(═O)—O— or —O—C(═O)—; D is CH or N; R4 is, for example, H, halogen, OH, SH, CN, nitro, C1-C6alkyl or C1-C6haloalkyl; R5 is, for example, C1-C12alkyl, C3-C8cycloalkyl or —N(R7)2; R7 is H, C1-C6alkyl, C1-C3haloalkyl, C1-C6alkylcarbonyl, C1-C3haloalkylcarbonyl, C1-C6alkoxycarbonyl, C3-C8cycloalkyl, C3-C8 cycloalkylcarbonyl or formyl; k is 0, 1, 2, 3 or 4; m is 1 or 2; and q is 0, 1 or 2; and, where applicable, their possible E/Z isomers, E/Z isomeric mixtures and/or tautomers, in each case in free form or in salt form, a process for the preparation of those compounds and their use, pesticidal compositions in which the active ingredient has been selected from those compounds and agrochemically acceptable salts thereof, and a process for the preparation of those compositions and their use, to plant propagation material treated with those compositions, and a method of controlling pests.

摘要翻译： 下式化合物其中A0，A1和A2各自独立地为键或C1-C6亚烷基桥; A3是C1-C6亚烷基桥，其未被取代或被1-6个相同或不同的选自卤素和C 3 -C 8环烷基的取代基取代; Y是例如O，S，SO或SO 2; M为O或NOR6，X1和X2各自独立地为氟，氯或溴; R1，R2和R3是例如H，卤素，OH，SH，CN，硝基，C1-C6烷基，C1-C6卤代烷基，C1-C6烷基羰基，C2-C6链烯基，C2-C6卤代烯基或C2-C6炔基; Q是例如O，S，SO或SO 2; W是例如O，S，SO，SO 2，-C（-O）-O-或-O-C（-O） - ; T是例如键O，S，SO，SO 2，-C（-O）-O-或-O-C（-O） - ; D是CH或N; R4是例如H，卤素，OH，SH，CN，硝基，C1-C6烷基或C1-C6卤代烷基; R5是例如C1-C12烷基，C3-C8环烷基或-N（R7）2; R 7是H，C 1 -C 6烷基，C 1 -C 3卤代烷基，C 1 -C 6烷基羰基，C 1 -C 3卤代烷基羰基，C 1 -C 6烷氧基羰基，C 3 -C 8环烷基，C 3 -C 8环烷基羰基或甲酰基; k为0，1，2，3或4; m为1或2; q为0,1或2; 在适用情况下，它们可能的E / Z异构体，E / Z异构体混合物和/或互变异构体，在每种情况下为游离形式或盐形式，制备这些化合物及其用途的方法，其中 已经从这些化合物和农业化学上可接受的盐中选择活性成分，以及这些组合物的制备方法及其用途，用这些组合物处理的繁殖材料以及控制害虫的方法。