公开(公告)号：US20050153322A1

公开(公告)日：2005-07-14

申请号：US10990246

申请日：2004-11-16

申请人： Paul Sheppard ,  Paul Bishop

发明人： Paul Sheppard ,  Paul Bishop

IPC分类号： A61K38/00 ,  C07K14/47 ,  C12Q1/68 ,  A61K38/17 ,  G01N33/53 ,  G01N33/567

CPC分类号： C07K14/52 ,  A61K38/00 ,  C07K14/4702 ,  C07K2319/00 ,  C12Q1/6888 ,  C12Q2600/158

摘要： The present invention provides novel uses two members of a new family of human proteins, designated as “Zven,” as agents that stimulate gastrointestinal contractility, gastric emptying, intestinal transit, and treating gastroparesis The Zven1 gene, which resides in human chromosome 3p21.1-3p14.3, is expressed in testicular tissue and peripheral blood lymphocytes.

摘要翻译： 本发明提供新的用途，称为“Zven”的新家族人类蛋白质的两个成员，作为刺激胃肠收缩力，胃排空，肠道运输和治疗胃轻瘫的药物。位于人染色体3p21.1中的Zven1基因 -3p14.3，表达于睾丸组织和外周血淋巴细胞。

公开(公告)号：US20070074120A1

公开(公告)日：2007-03-29

申请号：US11223455

申请日：2005-09-09

申请人： Gregory Lindhorst ,  Andrew Miller ,  Cyrus Balsara ,  Jason Bould ,  Jianlan Song ,  Neil Black ,  Paul Bishop

发明人： Gregory Lindhorst ,  Andrew Miller ,  Cyrus Balsara ,  Jason Bould ,  Jianlan Song ,  Neil Black ,  Paul Bishop

IPC分类号： G06F3/00

CPC分类号： G06F17/30867 ,  G06F9/451 ,  Y10S707/99945

摘要： A rich client view of server data is integrated within a server presentation of data provided by a portal server application. The rich client view of data is included with other web based views provided according to the server presentation of data when the rich client view is created. The rich client view is integrated among the web based views such that the rich client view and web based views are organized together. A separate application is launched to render the rich client view in response to a selection to render the rich client view. The selection to render the rich client view is integrated within the server presentation of data such that rich client view is provided seamlessly within the server presentation.

摘要翻译： 服务器数据的丰富客户端视图集成在由门户服务器应用程序提供的数据的服务器呈现中。 丰富的客户端数据视图包含在创建富客户端视图时根据数据的服务器呈现提供的其他基于Web的视图。 丰富的客户端视图集成在基于Web的视图中，从而将富客户端视图和基于Web的视图组织在一起。 启动单独的应用程序来呈现富客户端视图以响应选择来呈现富客户端视图。 呈现富客户端视图的选择集成在数据的服务器呈现之中，使得在服务器呈现中无缝提供丰富的客户端视图。

公开(公告)号：US20070021334A1

公开(公告)日：2007-01-25

申请号：US10558606

申请日：2004-05-28

申请人： Paul Bishop

发明人： Paul Bishop

IPC分类号： A61K38/17

CPC分类号： A61K31/00

摘要： The invention relates to the use of an agent that promotes class III SLRP activity in the manufacture of a medicament for the inhibition of blood vessel formation. In addition the invention relates to the use of an agent that promotes class III SLRP activity in the manufacture of a medicament for the prevention and/or treatment of conditions characterized by excessive activity and/or migration of monocytes and/or macrophages. Suitable agents may include class III SLRPs such as opticin. Methods of treatment using agents able to promote class III SLRP activity are also provided.

摘要翻译： 本发明涉及在制备用于抑制血管形成的药物中促进III类SLRP活性的药剂的用途。 此外，本发明涉及在制备用于预防和/或治疗特征为单核细胞和/或巨噬细胞的过度活性和/或迁移的病症的药物中促进III类SLRP活性的药剂的用途。 合适的试剂可以包括III类SLRP，例如视神经素。 还提供了使用能够促进III类SLRP活性的试剂的治疗方法。

公开(公告)号：US20070015709A1

公开(公告)日：2007-01-18

申请号：US11521902

申请日：2006-09-15

申请人： Jan Ohrstrom ,  Lynn Rose ,  Paul Bishop

发明人： Jan Ohrstrom ,  Lynn Rose ,  Paul Bishop

IPC分类号： A61K38/37

CPC分类号： A61K38/36 ,  A61K38/45 ,  A61K38/4846 ,  A61K2300/00

摘要： Use of factor XIII for treating hemophilia B. A patient having hemophilia B is treated by administering factor XIII, generally in conjunction with factor IX.

摘要翻译： 使用因子XIII治疗血友病B.患有血友病B的患者通过施用因子XIII进行治疗，通常与因子IX结合。

公开(公告)号：US20050222032A1

公开(公告)日：2005-10-06

申请号：US11133823

申请日：2005-05-20

申请人： Christopher Piddington ,  Paul Bishop

发明人： Christopher Piddington ,  Paul Bishop

IPC分类号： A61K38/00 ,  A61K38/17 ,  C07K14/47

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C07K14/47 ,  C07K2319/00 ,  C12N2799/026

摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp2, a novel member of the family of proteins bearing a collagen-like domain and a C1q domain. The polypeptides and polynucleotides encoding them, are involved in dimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp2 polypeptides.

摘要翻译： 本发明涉及用于zacrp2的多核苷酸和多肽分子，其是具有胶原样结构域和C1q结构域的蛋白家族的新成员。 编码它们的多肽和多核苷酸参与二聚化或低聚反应，并可用于其研究。 本发明还包括针对zacrp2多肽的抗体。

公开(公告)号：US10214899B2

公开(公告)日：2019-02-26

申请号：US15597715

申请日：2017-05-17

申请人： Paul Bishop ,  James Boyd Shaible

发明人： Paul Bishop ,  James Boyd Shaible

IPC分类号： E04B1/72 ,  E04F11/18

摘要： An improved handrail for a staircase or ramp. In one embodiment, the handrail includes an elongated member such as a cylinder or bar that spans the length of the staircase or ramp and a riser barrier. The riser barrier has an extender portion and a riser portion. The extender portion of the riser barrier keeps the elongated member a sufficient distance horizontally from the riser portion that a person can slide his or her hand on the rail without interference. The riser portion projects vertically a sufficient distance above the elongated member to deter sliding down the elongated member. Thus, sliding on the member is deterred, while the function of the cylinder as a handrail is preserved.

公开(公告)号：US09663942B2

公开(公告)日：2017-05-30

申请号：US15089220

申请日：2016-04-01

申请人： Paul Bishop ,  James Boyd Shaible

发明人： Paul Bishop ,  James Boyd Shaible

IPC分类号： E04B1/72 ,  E04F11/18

CPC分类号： E04B1/72 ,  E04F11/18 ,  E04F2011/1868

摘要： An improved handrail for a staircase or ramp. In one embodiment, the handrail includes an elongated member such as a cylinder or bar that spans the length of the staircase or ramp and a riser barrier. The riser barrier has an extender portion and a riser portion. The extender portion of the riser barrier keeps the elongated member a sufficient distance horizontally from the riser portion that a person can slide his or her hand on the rail without interference. The riser portion projects vertically a sufficient distance above the elongated member to deter sliding down the elongated member. Thus, sliding on the member is deterred, while the function of the cylinder as a handrail is preserved.

公开(公告)号：US09334656B2

公开(公告)日：2016-05-10

申请号：US12834833

申请日：2010-07-12

申请人： Paul Bishop ,  James Boyd Schaible

发明人： Paul Bishop ,  James Boyd Schaible

IPC分类号： E04F11/18

CPC分类号： E04B1/72 ,  E04F11/18 ,  E04F2011/1868

摘要： An improved handrail for a staircase or ramp. In one embodiment, the handrail includes an elongated member such as a cylinder or bar that spans the length of the staircase or ramp and a riser barrier. The riser barrier has an extender portion and a riser portion. The extender portion of the riser barrier keeps the elongated member a sufficient distance horizontally from the riser portion that a person can slide his or her hand on the rail without interference. The riser portion projects vertically a sufficient distance above the elongated member to deter sliding down the elongated member. Thus, sliding on the member is deterred, while the function of the cylinder as a handrail is preserved.

摘要翻译： 一个改进的扶手用于楼梯或斜坡。 在一个实施例中，扶手包括跨越楼梯或斜坡的长度的细长构件，例如圆柱体或杆，以及提升器屏障。 提升器屏障具有延伸部分和提升部分。 提升器屏障的延伸部分保持细长构件与提升部分的水平距离足够的距离，人可以在轨道上滑动他或她的手而不受干扰。 立管部分在细长构件上方垂直地突出足够的距离以阻止细长构件滑动。 因此，阻止在构件上的滑动，同时保持作为扶手的气缸的功能。

公开(公告)号：US20070014301A1

公开(公告)日：2007-01-18

申请号：US11235436

申请日：2005-09-26

申请人： Lawrence Miller ,  Paul Bishop

发明人： Lawrence Miller ,  Paul Bishop

IPC分类号： H04L12/56

CPC分类号： H04L61/2084 ,  H04L29/12066 ,  H04L29/12311 ,  H04L29/1233 ,  H04L61/1511 ,  H04L61/2061 ,  H04L61/25 ,  H04L67/24 ,  H04W8/04 ,  H04W8/26 ,  H04W80/04

摘要： Certain embodiments of the present invention provide a method and system for improved static address translation. Certain embodiments include a method for address translation in a network, wherein the network includes a device associated with an identifier and assigned a dynamic address. The method includes matching the identifier for the device to a static address; creating an address mapping between the dynamic address assigned to the device and the static address; and transmitting data to and from the device using the address mapping. The method may also include transmitting a record indicating a presence of the device on the network, wherein the record includes the identifier for the device. Additionally, the method may include providing the address mapping to a router for routing data between the device and another entity. The method may automatically create the address mapping between the dynamic address and the static address, for example.

摘要翻译： 本发明的某些实施例提供了一种用于改进静态地址转换的方法和系统。 某些实施例包括用于网络中的地址转换的方法，其中网络包括与标识符相关联的设备并且分配了动态地址。 该方法包括将设备的标识符与静态地址进行匹配; 在分配给设备的动态地址和静态地址之间创建地址映射; 并使用地址映射向设备发送数据。 该方法还可以包括在网络上发送指示设备的存在的记录，其中该记录包括该设备的标识符。 另外，该方法可以包括向路由器提供地址映射以在设备和另一实体之间路由数据。 例如，该方法可以自动创建动态地址和静态地址之间的地址映射。

公开(公告)号：US20060252692A1

公开(公告)日：2006-11-09

申请号：US11479928

申请日：2006-06-29

申请人： Gerald Lasser ,  Paul Bishop ,  Joachim Fruebis ,  Woerner Meehan

发明人： Gerald Lasser ,  Paul Bishop ,  Joachim Fruebis ,  Woerner Meehan

IPC分类号： A61K38/39

CPC分类号： A61K38/49 ,  A61K38/1709 ,  A61K2300/00

摘要： The present invention relates to peptide, polynucleotide and fusion proteins for use as inhibitors in hemostasis. These inhibitors are members of the family of proteins bearing a collagen-like domain and a globular domain. The inhibitors are useful for promoting blood flow in the vasculature by reducing thrombogenic and complement activity. The inhibitors are also useful for pacify collagenous surfaces and modulating wound healing.