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公开(公告)号：US20060034866A1
公开(公告)日：2006-02-16
申请号：US11256802
申请日：2005-10-24
IPC分类号： A61K39/00 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C07K14/472 , A61K38/00 , C07K14/4702 , C07K2319/02
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp3, a novel member of the family of proteins bearing a collagen-like domain and a C1q domain. The polypeptides and polynucleotides encoding them, are involved in dimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp3 polypeptides.
摘要翻译： 本发明涉及用于zacrp3的多核苷酸和多肽分子，其是具有胶原样结构域和C1q结构域的蛋白质家族的新成员。 编码它们的多肽和多核苷酸参与二聚化或低聚反应，并可用于其研究。 本发明还包括针对zacrp3多肽的抗体。
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公开(公告)号：US20050222032A1
公开(公告)日：2005-10-06
申请号：US11133823
申请日：2005-05-20
CPC分类号： C07K14/4702 , A61K38/00 , C07K14/47 , C07K2319/00 , C12N2799/026
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp2, a novel member of the family of proteins bearing a collagen-like domain and a C1q domain. The polypeptides and polynucleotides encoding them, are involved in dimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp2 polypeptides.
摘要翻译： 本发明涉及用于zacrp2的多核苷酸和多肽分子，其是具有胶原样结构域和C1q结构域的蛋白家族的新成员。 编码它们的多肽和多核苷酸参与二聚化或低聚反应，并可用于其研究。 本发明还包括针对zacrp2多肽的抗体。
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公开(公告)号：US20050042719A1
公开(公告)日：2005-02-24
申请号：US10676790
申请日：2003-10-01
IPC分类号： C07H21/04 , C07K14/705 , C07K14/72 , C07K14/78
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp5, a novel member of the family of proteins bearing a collagen-like domain and a Clq domain. The polypeptides and polynucleotides encoding them, are involved in trimerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp5 polypeptides.
摘要翻译： 本发明涉及用于zacrp5的多核苷酸和多肽分子，其是具有胶原样结构域和Clq结构域的蛋白家族的新成员。 编码它们的多肽和多核苷酸参与三聚化并且可以用于其研究。 本发明还包括针对zacrp5多肽的抗体。
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公开(公告)号：US20060040360A1
公开(公告)日：2006-02-23
申请号：US11258647
申请日：2005-10-25
IPC分类号： C07K14/705 , C07H21/04
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/00 , C12N2799/026
摘要： The present invention relates to polynucleotide and polypeptide molecules for zacrp7, a novel member of the family of proteins bearing a collagen-like domain and a Clq domain. The polypeptides and polynucleotides encoding them, are involved in homo and heterotrimerization or oligomerization and may be used in the study thereof. The present invention also includes antibodies to the zacrp7 polypeptides.
摘要翻译： 本发明涉及用于zacrp7的多核苷酸和多肽分子，其是具有胶原样结构域和Clq结构域的蛋白家族的新成员。 编码它们的多肽和多核苷酸参与同源和异三聚或寡聚化，并可用于其研究。 本发明还包括针对zacrp7多肽的抗体。
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公开(公告)号：US20070141056A1
公开(公告)日：2007-06-21
申请号：US11552362
申请日：2006-10-24
IPC分类号： A61K39/395 , C07K16/24
CPC分类号： C07K14/52 , A01K2217/05 , A61K38/1858 , C07K14/475 , C12N2799/022
摘要： Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 90% identical to residues 46-163 of SEQ ID NO: 2 or residues 235-345 of SEQ ID NO: 2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
摘要翻译： 公开了多肽生长因子，其制备方法，编码它们的多核苷酸，针对它们的抗体以及使用它们的方法。 多肽包含与SEQ ID NO：2的残基46-163或SEQ ID NO：2的残基235-345至少90％相同的氨基酸区段。多肽的多聚体也被公开。 多肽，多聚体蛋白和多核苷酸可用于细胞和组织发育的研究和调节，作为细胞培养基的组分和诊断剂。
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公开(公告)号：US20070060507A1
公开(公告)日：2007-03-15
申请号：US11552378
申请日：2006-10-24
IPC分类号： A61K38/18 , C07K14/475
CPC分类号： C07K14/52 , A01K2217/05 , A61K38/1858 , C07K14/475 , C12N2799/022
摘要： Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 90% identical to residues 46-163 of SEQ ID NO:2 or residues 235-345 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
摘要翻译： 公开了多肽生长因子，其制备方法，编码它们的多核苷酸，针对它们的抗体以及使用它们的方法。 多肽包含与SEQ ID NO：2的残基46-163或SEQ ID NO：2的残基235-345至少90％相同的氨基酸区段。 还公开了多肽的多聚体。 多肽，多聚体蛋白和多核苷酸可用于细胞和组织发育的研究和调节，作为细胞培养基的组分和诊断剂。
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公开(公告)号：US20050159358A1
公开(公告)日：2005-07-21
申请号：US11021088
申请日：2004-12-22
申请人： Zeren Gao , Charles Hart , Christopher Piddington , Paul Sheppard , Kimberly Shoemaker , Debra Gilbertson , James West
发明人： Zeren Gao , Charles Hart , Christopher Piddington , Paul Sheppard , Kimberly Shoemaker , Debra Gilbertson , James West
IPC分类号： A61K38/00 , A61K38/18 , C07K14/475 , C07K14/52 , C07H21/04
CPC分类号： C07K14/52 , A01K2217/05 , A61K38/1858 , C07K14/475 , C12N2799/022
摘要： Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 90% identical to residues 46-163 of SEQ ID NO:2 or residues 235-345 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.
摘要翻译： 公开了多肽生长因子，其制备方法，编码它们的多核苷酸，针对它们的抗体以及使用它们的方法。 所述多肽包含与SEQ ID NO：2的残基46-163或SEQ ID NO：2的残基235-345至少90％相同的氨基酸区段。 还公开了多肽的多聚体。 多肽，多聚体蛋白和多核苷酸可用于细胞和组织发育的研究和调节，作为细胞培养基的组分和诊断剂。
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