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    ACOUSTIC DEVICE FOR ULTRASONIC IMAGING
    12.
    发明申请
    ACOUSTIC DEVICE FOR ULTRASONIC IMAGING 审中-公开
    用于超声波成像的声学设备

    公开(公告)号：US20120022375A1

    公开(公告)日：2012-01-26

    申请号：US13146066

    申请日：2010-01-25

    申请人： Szabolcs Deladi ,  Jan Frederik Suijver ,  David Maresca

    发明人： Szabolcs Deladi ,  Jan Frederik Suijver ,  David Maresca

    IPC分类号： A61B8/12 ,  A61B8/13 ,  A61B8/00

    CPC分类号： G10K11/30

    摘要： The present invention relates to an acoustic device for ultrasonic imaging of an object (21). The device comprises an acoustic transducer (10 and an acoustic lens (20) arranged to variably refract the said acoustic pulse to and/or from the acoustic transducer. The acoustic lens comprising a first (L1) and a second fluid (L2) being separated by an acoustic interface (7), the normal of the said acoustic interface forming a relative angle of incidence (AI) with the said acoustic pulse, e.g. an electrowetting lens. The first and the second fluid of the acoustic lens (20) are specifically chosen so that the acoustic interface (7) has a reflection minima at a non-zero relative angle of incidence (AI). The invention is advantageous for obtaining an improved acoustic device having a substantially lower reflection in a broader interval of incidence angles as compared to hitherto seen ultrasonic imaging utilising acoustic lenses with two or more fluids as the active acoustic refracting entities.

    摘要翻译： 本发明涉及一种用于物体（21）的超声波成像的声学装置。 该装置包括声换能器（10和声透镜），该声透镜被布置成可将声脉冲可变地折射到声换能器和/或从该声换能器。声学透镜包括分离的第一液体（L1）和第二流体（L2） 通过声学接口（7），所述声学接口的法线形成与所述声学脉冲（例如电润湿透镜）的相对入射角（AI），声透镜的第一和第二流体 被选择使得声学接口（7）具有非零相对入射角（AI）的反射最小值。本发明有利于获得具有较大入射角的基本上较低的反射的改进的声学装置， 到目前为止，使用具有两种或多种流体的声透镜作为主动声学折射实体的超声波成像。

    FLUID LENS WITH PRESSURE RELEASE SYSTEM
    13.
    发明申请
    FLUID LENS WITH PRESSURE RELEASE SYSTEM 有权
    带压力释放系统的流体镜

    公开(公告)号：US20100277809A1

    公开(公告)日：2010-11-04

    申请号：US12811831

    申请日：2009-01-12

    申请人： Jan Frederik Suijver ,  Stein Kuiper ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Szabolcs Deladi ,  Antonius Johannes Josephus Rademakers ,  Cornelius Antonius Micolaas Maria Van Der Vleuten ,  Johannes Wilhelmus Weekamp ,  Waltherus Cornelis Jozef Bierhoff

    发明人： Jan Frederik Suijver ,  Stein Kuiper ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Szabolcs Deladi ,  Antonius Johannes Josephus Rademakers ,  Cornelius Antonius Micolaas Maria Van Der Vleuten ,  Johannes Wilhelmus Weekamp ,  Waltherus Cornelis Jozef Bierhoff

    IPC分类号： G02B3/14 ,  A61B1/06

    CPC分类号： G02B7/008 ,  A61B1/0019 ,  G02B3/14 ,  G02B23/2407

    摘要： Fluid lens system, e.g. for medical imaging or medical treatment, with a container enclosing a fluid arranged to refract incoming waves. A pressure release mechanism is in contact with the fluid so as to compensate changes in its volume due to thermal variations, e.g. during high temperature medical cleaning. This pressure release mechanism is positioned within a pathway of incoming waves. In preferred embodiments a fluid container connected via a tube to the fluid as a reservoir, is arranged within or outside the container, e.g. beyond an image sensor. Alternatively, an easily compressible body, e.g. a small closed metal bellows enclosing a gas, is positioned inside the fluid to absorb volume changes by compression. In both embodiments, the pressure release elements are preferably positioned in a peripheral part of the pathway of incoming waves to not affect performance of the lens. In another aspect, a fluid lens includes a container with an inner container part that fits inside an outer container part, wherein the inner container part is in rigid connection to at least a one boundary arranged for penetration of incoming waves. The pressure release mechanism is positioned within the outer container part, and it is in contact with the fluid so as to compensate changes in volume of the fluid due to thermal variations. In one embodiment the inner and outer container parts are arranged for relative one-dimensional movement and fluid tight interconnected. In another embodiment, a fluid filled cavity is formed between the inner and outer container parts, and this cavity houses a compressible body. The lens systems are suited for applications such as medical endoscopes, catheters and needles, optically as well as acoustically based.

    摘要翻译： 流体透镜系统，例如 用于医疗成像或医疗处理，容器包围布置成折射入射波的流体。 压力释放机构与流体接触，以便补偿由于热变化引起的体积变化，例如， 在高温医疗清洗过程中。 该压力释放机构位于入射波的通路内。 在优选实施例中，经由管连接到作为储存器的流体的流体容器设置在容器内或外部，例如， 超越图像传感器。 或者，容易压缩的主体，例如， 围绕气体的小封闭金属波纹管位于流体内部以通过压缩吸收体积变化。 在两个实施例中，压力释放元件优选地定位在入射波通路的周边部分中，从而不影响透镜的性能。 在另一方面，一种流体透镜包括具有内部容器部分的容器，该内部容器部分装配在外部容器部分内部，其中内部容器部分刚好连接至布置成用于穿透入射波的至少一个边界。 压力释放机构定位在外部容器部分内，并且与流体接触，以补偿由于热变化引起的流体体积的变化。 在一个实施例中，内部和外部容器部件布置用于相对一维运动并且流体密封互连。 在另一个实施例中，在内部和外部容器部分之间形成流体填充空腔，并且该空腔容纳可压缩体。 透镜系统适用于诸如医用内窥镜，导管和针的应用，光学和声学基础。

    HYDROGEL BASED SENSOR PROBE FOR DETECTING AN ENVIRONMENTAL STATE
    14.
    发明申请
    HYDROGEL BASED SENSOR PROBE FOR DETECTING AN ENVIRONMENTAL STATE 失效
    用于检测环境状态的基于HYDROGEL的传感器探测器

    公开(公告)号：US20100162834A1

    公开(公告)日：2010-07-01

    申请号：US12600881

    申请日：2008-05-22

    申请人： Bernardus Hendrikus Wilhelmus Hendriks ,  Szabolcs Deladi ,  Ralph Kurt ,  Jan Frederik Suijver

    发明人： Bernardus Hendrikus Wilhelmus Hendriks ,  Szabolcs Deladi ,  Ralph Kurt ,  Jan Frederik Suijver

    IPC分类号： G01D21/00 ,  G01B11/22

    CPC分类号： G01N21/7703 ,  A61B5/0084 ,  A61B5/14539 ,  G01N2021/772 ,  G01N2021/7723 ,  G01N2021/773 ,  G01N2021/7779

    摘要： The invention relates to a sensor probe (100,110,120,130,140,150) for detecting an environmental state within a bodily lumen. The sensor probe (100,110,120,130,140,150) having an elongated body (9) comprises an optical guide (1) having an outcoupling surface (11), which is part of an end surface (3) of the elongated body (9), facing a reflective surface of an overhanging part (22,42,52,62), a photodetector which detects a property of light which is composed of light (32) in the optical guide (1) that is reflected from the outcoupling surface (11) of the optical guide (1) and of light (33) in the optical guide (1) that is reflected from the overhanging part (22,42,52,62), and a hydrogel material (2) of which a property changes when getting into contact with an environmental material and/or when detecting an environmental change, and which is provided between the end surface (3) of the elongated body (9) and the overhanging part (22,42,52,62). In this way a sensor probe (100,110,120,130,140,150) is provided that, because of its compactness, can be applied inside the bodily lumen for detecting and characterizing parameters that are vital indicators for the state of the human or animal body, and to which the hydrogel material (2) is responsive.

    摘要翻译： 本发明涉及一种用于检测体腔内的环境状态的传感器探针（100,110,120,130,140,​​150）。 具有细长主体（9）的传感器探针（100,110,130,140,​​150）包括具有外耦合表面（11）的光导（1），该外耦合表面（11）是细长主体（9）的端表面（3）的一部分，面向反射表面 突出部分（22,42,52,62）的光检测器，其检测由光导（1）中的光（32）组成的光的属性，所述光从光耦合表面（11）反射 在导光体（1）中从突出部分（22,42,52,62）反射的导光体（1）和光（33）以及在接触时性质发生变化的水凝胶材料（2） 和环境材料和/或当检测到环境变化时，并且设置在细长体（9）的端面（3）与伸出部分（22,42,52,62）之间。 以这种方式，提供传感器探针（100,110,120,130,140,​​150），由于其紧凑性，可以在身体内部施加以检测和表征作为人体或动物体状态的重要指标的参数，并且将水凝胶材料 （2）有反应。

    Hydrogel based sensor probe for detecting an environmental state
    15.
    发明授权
    Hydrogel based sensor probe for detecting an environmental state 失效
    用于检测环境状态的基于水凝胶的传感器探头

    公开(公告)号：US08244078B2

    公开(公告)日：2012-08-14

    申请号：US12600881

    申请日：2008-05-22

    申请人： Bernardus Hendrikus Wilhelmus Hendriks ,  Szabolcs Deladi ,  Ralph Kurt ,  Jan Frederik Suijver

    发明人： Bernardus Hendrikus Wilhelmus Hendriks ,  Szabolcs Deladi ,  Ralph Kurt ,  Jan Frederik Suijver

    IPC分类号： G02B6/00

    CPC分类号： G01N21/7703 ,  A61B5/0084 ,  A61B5/14539 ,  G01N2021/772 ,  G01N2021/7723 ,  G01N2021/773 ,  G01N2021/7779

    摘要： A sensor probe for detecting an environmental state within a bodily lumen includes an elongated body having an optical guide with an outcoupling surface, which is part of an end surface of the elongated body, facing a reflective surface of an overhanging part. The sensor probe further includes a photodetector which detects a property of light which is composed of light in the optical guide that is reflected from the outcoupling surface of the optical guide and of light in the optical guide that is reflected from the overhanging part. The sensor probe also includes a hydrogel material having a property that changes when getting into contact with an environmental material and/or when detecting an environmental change. The hydrogel material is provided between the end surface of the elongated body and the overhanging part.

    摘要翻译： 用于检测身体腔内的环境状态的传感器探针包括细长体，其具有带有外耦合表面的光导，所述光耦合器是细长体的端表面的一部分，面向突出部分的反射表面。 传感器探头还包括光电检测器，其检测由光导中的光构成的光的特性，所述光从光导的输出耦合表面反射，以及从突出部反射的光导中的光。 传感器探头还包括具有在与环境材料接触和/或当检测到环境变化时变化的性质的水凝胶材料。 水凝胶材料设置在细长体的端面与突出部之间。

    ADJUSTABLE LENS SYSTEM FOR REAL-TIME APPLICATIONS
    19.
    发明申请
    ADJUSTABLE LENS SYSTEM FOR REAL-TIME APPLICATIONS 失效
    可调镜头系统实时应用

    公开(公告)号：US20100259832A1

    公开(公告)日：2010-10-14

    申请号：US12742658

    申请日：2008-12-10

    申请人： Jan Frederik Suijver ,  Christopher Stephen Hall ,  Anna Teresa Fernandez ,  Stein Kuiper ,  Yan Shi

    发明人： Jan Frederik Suijver ,  Christopher Stephen Hall ,  Anna Teresa Fernandez ,  Stein Kuiper ,  Yan Shi

    IPC分类号： G02B3/14

    CPC分类号： G02B3/14

    摘要： An adjustable fluid type lens system is provided that allows e.g. ultrasound imaging through the lens during adjustment of the lens. The lens includes a container enclosing two immiscible fluids, e.g. water and oil, being in contact with each other at an interface. Incoming waves are then refracted at this interface. The shape of the interface, and thereby the refraction property, is adjustable by adjusting a voltage applied to the lens. The two fluids are selected such that they together exhibit a mechanical damping which is critical or near critical. A control circuit generates the electric voltage for adjusting the refraction from one value to another, the control circuit being arranged to change the electric voltage such that a rate of voltage change is limited to avoid oscillation of the interface, thereby adjusting refraction of incoming waves at the interface in a continuous manner. This makes it possible to use the lens while it is during adjustment from one refraction value to another, since the interface shape will at all time during the adjustment have a controlled shape. The voltage can be either a continuous voltage or a discrete stepwise (digital) voltage which is just controlled with respect to step size and temporal extension of the steps. The lens system has a number of applications e.g. within the medical field, e.g. for ‘on the fly’ high speed ultrasound imaging, or for ultrasound ablation applications where ablation can be performed during adjustment of the lens to follow a pre-defined trajectory.

    摘要翻译： 提供了一种可调节流体型透镜系统， 超声波成像通过透镜在调整镜片期间。 透镜包括容纳两个不混溶流体的容器，例如 水和油在界面处彼此接触。 然后在这个界面折射出来的波。 通过调节施加到透镜上的电压来调节界面的形状以及由此的折射特性。 选择两种流体使得它们一起显示出关键或近临界的机械阻尼。 控制电路产生用于将折射率从一个值调整到另一个值的电压，控制电路被布置成改变电压，使得电压变化率被限制以避免界面的振荡，由此调节入射波的折射 界面以连续的方式。 这使得可以在从一个折射值到另一个折射值的调整期间使用透镜，因为在调节期间的所有时间的界面形状都具有受控的形状。 电压可以是连续电压或离散的逐步（数字）电压，其仅仅相对于步长的步长和时间延长而被控制。 透镜系统具有许多应用，例如， 在医疗领域内。 用于“飞行”高速超声成像，或用于超声消融应用，其中可以在镜片调节期间遵循预定义的轨迹进行消融。

    DEVICE CONTAINING A FLUID REFRACTING ULTRASOUND MODALITY
    20.
    发明申请
    DEVICE CONTAINING A FLUID REFRACTING ULTRASOUND MODALITY 审中-公开
    含有流体超薄超声波模型的装置

    公开(公告)号：US20100229648A1

    公开(公告)日：2010-09-16

    申请号：US12438170

    申请日：2007-04-12

    申请人： Jan Frederik Suijver ,  Anna T. Fernandez ,  Christopher S. Hall

    发明人： Jan Frederik Suijver ,  Anna T. Fernandez ,  Christopher S. Hall

    IPC分类号： G01N29/02

    CPC分类号： G10K11/30

    摘要： An acoustic device is disclosed having a variably refracting acoustic fluid interface including the boundary between two separate fluid media, means for directing acoustic waves onto the interface, and an acoustic generator or transducer located in one of the fluid media with the acoustic generator having an impedance that is substantially equal to the one said fluid media to minimize signal loss and reflection.

    摘要翻译： 公开了一种声学装置，其具有包括两个单独流体介质之间的边界的可变折射声流体界面，用于将声波引导到界面上的装置，以及位于一个流体介质中的声发生器或换能器，声发生器具有阻抗 其基本上等于所述流体介质以最小化信号损失和反射。