公开(公告)号：US20230295652A1

公开(公告)日：2023-09-21

申请号：US18147156

申请日：2022-12-28

Applicant: TOOLGEN INCORPORATED

Inventor： Seokjoong KIM ,  Dong Woo SONG ,  Jae Young LEE ,  Jung Min LEE ,  Gyu-bon CHO ,  Hee Sook BAE

IPC: C12N15/85 ,  C12N15/113 ,  C12N9/22

CPC classification number: C12N15/85 ,  C12N9/22 ,  C12N15/113 ,  C12N2310/20

Abstract: The present invention relates to an expression control composition for controlling the expression of a duplicate gene or a method using the same. In addition, the present invention relates to a method of treating or improving a disease caused by gene duplication using the expression control composition for controlling the expression of a duplicate gene.

公开(公告)号：US20220192163A1

公开(公告)日：2022-06-23

申请号：US17440350

申请日：2020-03-24

Applicant: TOOLGEN INCORPORATED

Inventor： Jae Young LEE ,  Hee Sook BAE ,  Hye Jung SHIN ,  Dong Woo SONG ,  Un Gi KIM ,  Kyu Jun LEE

IPC: A01K67/027 ,  C12N15/10 ,  C12N15/113 ,  C12N15/85 ,  C12N15/90 ,  C12N9/64

Abstract: The present invention relates to a hemophilia B rat and a method of producing the hemophilia B rat. More particularly, the present invention relates to a hemophilia B rat having F9 factor knocked-down or knocked-out and a method of producing the hemophilia B rat.