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    LACTIC ACID PRODUCTION METHOD
    12.
    发明申请
    LACTIC ACID PRODUCTION METHOD 有权
    柠檬酸生产方法

    公开(公告)号：US20100190222A1

    公开(公告)日：2010-07-29

    申请号：US12666690

    申请日：2008-06-18

    申请人： Masateru Ito ,  Shin-ichi Minegishi ,  Eri Shimizu ,  Kenji Sawai ,  Yohito Ito ,  Hideki Sawai ,  Katsushige Yamada

    发明人： Masateru Ito ,  Shin-ichi Minegishi ,  Eri Shimizu ,  Kenji Sawai ,  Yohito Ito ,  Hideki Sawai ,  Katsushige Yamada

    IPC分类号： C12P7/56

    CPC分类号： C12P7/56 ,  B01D61/027 ,  B01D71/56 ,  B01D2311/06 ,  B01D2311/18 ,  B01D2311/2669

    摘要： Disclosed is a lactic acid production method by separating lactic acid produced in a culture solution by means of the fermentation culture of a microorganism. Specifically disclosed is a lactic acid production method, which comprises: a step (A) of filtering the culture solution through a nano-filtration membrane; and a step (B) of distilling a lactic-acid-containing solution produced in the step (A) under a pressure ranging from 1 Pa to the atmospheric pressure (inclusive) at a temperature ranging from 25 to 200° C. (inclusive) to collect lactic acid. The method can effectively remove an inorganic salt dissolved in a fermentation culture solution or contained in the fermentation culture solution in the form of a poorly soluble solid material by a simple manipulation, enables to prevent the racemization or oligomerization of lactic acid during the process of producing lactic acid, and therefore can produce lactic acid in a high yield.

    摘要翻译： 公开了通过微生物的发酵培养分离培养液中产生的乳酸的乳酸生产方法。 具体公开的是乳酸的制造方法，其包括：通过纳滤膜过滤培养液的工序（A） 和（B）在步骤（A）中制备的含乳酸的溶液在25Pa至200℃的温度范围内，在1Pa至大气压（含）范围内， 收集乳酸。 该方法可以通过简单的操作有效地除去溶解在发酵培养液中的无机盐或发酵培养液中含有的难溶性固体物质的形式的无机盐，能够防止生产过程中乳酸的外消旋化或低聚反应 乳酸，因此可以高产率生产乳酸。

    BUTANOL MANUFACTURING METHOD
    13.
    发明申请
    BUTANOL MANUFACTURING METHOD 有权
    丁醇制造方法

    公开(公告)号：US20130041187A1

    公开(公告)日：2013-02-14

    申请号：US13635066

    申请日：2011-03-16

    申请人： Masateru Ito ,  Izumi Morita ,  Shinichi Yamane ,  Katsushige Yamada

    发明人： Masateru Ito ,  Izumi Morita ,  Shinichi Yamane ,  Katsushige Yamada

    IPC分类号： C07C29/76

    CPC分类号： C07B63/00 ,  B01D61/022 ,  B01D61/025 ,  B01D61/027 ,  B01D2311/06 ,  B01D2311/2646 ,  C07C29/76 ,  C12P7/16 ,  Y02E50/10 ,  C07C31/12

    摘要： Highly pure butanol can be produced by a method for producing butanol, the method comprising: Step A, wherein a butanol-containing solution is filtered through a nanofiltration membrane and a butanol-containing solution is recovered from the permeate side; Step B, wherein the butanol-containing solution obtained in Step A is passed through a reverse osmosis membrane and thereby concentrated to cause two-phase separation into a butanol phase and an aqueous phase; and Step C, wherein butanol is recovered from the butanol phase obtained in Step B.

    摘要翻译： 高纯度丁醇可以通过生产丁醇的方法生产，其方法包括：步骤A，其中将含丁醇的溶液通过纳滤膜过滤，从渗透侧回收含丁醇的溶液; 步骤B，其中将步骤A中获得的含丁醇的溶液通过反渗透膜，由此浓缩，使其两相分离成丁醇相和水相; 和步骤C，其中从步骤B中获得的丁醇中回收丁醇。

    METHOD FOR PRODUCING LACTATE
    14.
    发明申请
    METHOD FOR PRODUCING LACTATE 审中-公开
    生产羊皮的方法

    公开(公告)号：US20140012041A1

    公开(公告)日：2014-01-09

    申请号：US13993385

    申请日：2011-12-12

    申请人： Miyuki Horiguchi ,  Masateru Ito ,  Takeshi Munegumi ,  Katsushige Yamada

    发明人： Miyuki Horiguchi ,  Masateru Ito ,  Takeshi Munegumi ,  Katsushige Yamada

    IPC分类号： C07C51/42

    CPC分类号： C07C51/42 ,  C07C51/43 ,  C07C59/08

    摘要： A method produces a lactic acid salt and includes subjecting an aqueous lactic acid salt solution comprising a formic acid salt in an amount of not less than 7.0% by weight with respect to the lactic acid salt to crystallization, and recovering the lactic acid salt. By subjecting the aqueous lactic acid salt solution including a formic acid salt in an amount of not less than 7.0% by weight with respect to the lactic acid salt to crystallization, supersaturation of the lactic acid salt can be stabilized, and the recovery of the lactic acid salt can be increased.

    摘要翻译： 一种制造乳酸盐的方法，其特征在于，使含有甲酸盐的乳酸盐水溶液相对于乳酸盐为7.0重量％以上结晶化，回收乳酸盐。 通过使包含甲酸盐的乳酸盐水溶液相对于乳酸盐不低于7.0重量％进行结晶化，乳酸盐的过饱和度可以稳定，并且乳酸 酸盐可以增加。

    METHOD FOR PRODUCING LACTIC ACID AND METHOD FOR PRODUCING POLYLACTIC ACID
    17.
    发明申请
    METHOD FOR PRODUCING LACTIC ACID AND METHOD FOR PRODUCING POLYLACTIC ACID 审中-公开
    生产乳酸的方法和生产聚酸的方法

    公开(公告)号：US20110263811A1

    公开(公告)日：2011-10-27

    申请号：US13142062

    申请日：2009-12-25

    申请人： Kenji Sawai ,  Hideki Sawai ,  Takashi Mimitsuka ,  Ito Masateru ,  Katsushige Yamada ,  Kenji Kawamura ,  Shin-ichi Minegishi ,  Izumi Nakagawa ,  Tatsuya Nagano

    发明人： Kenji Sawai ,  Hideki Sawai ,  Takashi Mimitsuka ,  Ito Masateru ,  Katsushige Yamada ,  Kenji Kawamura ,  Shin-ichi Minegishi ,  Izumi Nakagawa ,  Tatsuya Nagano

    IPC分类号： C08G63/78 ,  C07D319/12 ,  C12P7/56

    摘要： Lactic acid is obtained by a method including (A) a step of continuous fermentation wherein a fermentation culture medium of a microorganism having an ability of lactic acid fermentation is filtered through a porous membrane having an average pore size of not less than 0.01 μm and less than 1 μm with a transmembrane pressure difference within the range of 0.1 to 20 kPa, and the permeate is collected, while retaining the non-permeated liquid in or returning the non-permeated liquid to the culture, and adding a fermentation feedstock to the culture; (B) a step of filtering the permeate obtained in Step (A) through a nanofiltration membrane; and (C) a step of distilling the permeate obtained in Step (B) under a pressure of not less than 1 Pa and not more than atmospheric pressure, at 25° C. to 200° C. to recover lactic acid.

    摘要翻译： 乳酸通过以下方法获得：（A）连续发酵步骤，其中具有乳酸发酵能力的微生物的发酵培养基通过平均孔径不小于0.01μm的多孔膜过滤 超过1μm，跨膜压力差在0.1〜20kPa的范围内，并收集渗透物，同时将非渗透液体保留在或将非渗透液体返回到培养物中，并向培养物中加入发酵原料 ; （B）通过纳滤膜对步骤（A）中得到的渗透物进行过滤的工序; 和（C）在25℃至200℃下，在不低于1Pa且不大于大气压的压力下，将步骤（B）中得到的渗透物蒸馏的步骤，以回收乳酸。

    METHOD OF PRODUCING LACTIC ACID BY CONTINUOUS FERMENTATION
    19.
    发明申请
    METHOD OF PRODUCING LACTIC ACID BY CONTINUOUS FERMENTATION 审中-公开
    连续发酵生产酸乳酸的方法

    公开(公告)号：US20140017746A1

    公开(公告)日：2014-01-16

    申请号：US14027754

    申请日：2013-09-16

    申请人： Nanami Sasaki ,  Ken Morita ,  Takashi Mimitsuka ,  Hideki Sawai ,  Katsushige Yamada

    发明人： Nanami Sasaki ,  Ken Morita ,  Takashi Mimitsuka ,  Hideki Sawai ,  Katsushige Yamada

    IPC分类号： C12P7/56

    CPC分类号： C12P7/56

    摘要： A method of producing lactic acid by continuous fermentation includes filtering a culture of polyploidy prototrophic yeast having a capacity to produce lactic acid by introduction of a lactate dehydrogenase gene through a porous membrane having an average pore size of not less than 0.01 μm and less than 1 μm; and recovering the lactic acid from filtrate while the unfiltered liquid is retained in or returned to the culture and a fermentation feedstock is added to the culture.

    摘要翻译： 通过连续发酵生产乳酸的方法包括通过将平均孔径不小于0.01μm和小于1的多孔膜引入乳酸脱氢酶基因来过滤具有产生乳酸能力的多倍体原养酵母的培养物 妈妈 并从滤液中回收乳酸，同时将未过滤的液体保留在培养物中或返回到培养物中，向培养物中加入发酵原料。

    METHOD FOR PRODUCING SUGAR SOLUTION
    20.
    发明申请
    METHOD FOR PRODUCING SUGAR SOLUTION 审中-公开
    生产糖溶液的方法

    公开(公告)号：US20140017736A1

    公开(公告)日：2014-01-16

    申请号：US14007438

    申请日：2012-03-28

    申请人： Hiroyuki Kurihara ,  Junpei Kishimoto ,  Katsushige Yamada

    发明人： Hiroyuki Kurihara ,  Junpei Kishimoto ,  Katsushige Yamada

    IPC分类号： C12P19/14

    CPC分类号： C12P19/14 ,  C12P19/02

    摘要： A method of producing a sugar liquid includes hydrolyzing with a filamentous fungus-derived cellulase a product obtained by adding a water-soluble inorganic salt(s) to a pretreated product of cellulose to a final concentration of 5 to 35 g/L; and subjecting the hydrolysate to solid-liquid separation and filtering the obtained solution component through an ultrafiltration membrane to recover the filamentous fungus-derived cellulase as a non-permeate and to obtain a sugar liquid as a permeate.

    摘要翻译： 制造糖液的方法包括用丝状真菌衍生的纤维素酶水解，将通过向纤维素的预处理物中加入水溶性无机盐而得到的产物，其终浓度为5〜35g / L; 并对该水解物进行固液分离，并通过超滤膜过滤得到的溶液成分，回收作为非渗透物的丝状真菌来源的纤维素酶，得到作为渗透物的糖液。