公开(公告)号：US07621889B2

公开(公告)日：2009-11-24

申请号：US11148454

申请日：2005-06-09

申请人： Thach Duong ,  Jay J. Eum ,  Jenny C. Liu

发明人： Thach Duong ,  Jay J. Eum ,  Jenny C. Liu

IPC分类号： A61F7/12

CPC分类号： A61F7/12 ,  A61F7/123 ,  A61F2007/126

摘要： An inlet flow of heat exchange fluid flows from an inflow housing inlet section, and through an inflow housing main section. It then flows through an inlet fluid passageway formed between an inner balloon and a discharge tube. The flow continues around a distal end of the inner balloon, thus becoming an outlet flow of the heat exchange fluid which is directed through an outlet fluid passageway formed between the inner balloon and an outer balloon, then through an outflow housing main section and finally discharged through an outflow housing outlet section. The inner balloon is in a position offset from the central axis of the catheter. The offset relationship enhances the fluid dynamic properties of the catheter. It provides an increased turbulence, which, in turn, maximizes the heat exchange efficiency.

摘要翻译： 热交换流体的入口流从流入壳体入口部分流过流入壳体主体部分。 然后流过形成在内气囊和放电管之间的入口流体通道。 流动继续围绕内球囊的远端，从而变成热交换流体的出口流动，该热交换流体被引导通过形成在内球囊和外球囊之间的出口流体通道，然后通过流出壳体主区段并最终排出 通过流出的外壳出口部分。 内囊处于从导管的中心轴线偏移的位置。 偏移关系增强了导管的流体动力学特性。 它提供了增加的湍流，从而使热交换效率最大化。

公开(公告)号：US07363071B2

公开(公告)日：2008-04-22

申请号：US10700326

申请日：2003-11-03

申请人： Sanford D. Damasco ,  Thach Duong ,  Jawahar M. Ali ,  David J. Battles ,  Paul W. Mikus ,  Jay J. Eum

发明人： Sanford D. Damasco ,  Thach Duong ,  Jawahar M. Ali ,  David J. Battles ,  Paul W. Mikus ,  Jay J. Eum

IPC分类号： A61B5/05

CPC分类号： A61B18/02 ,  A61B8/08 ,  A61B34/10 ,  A61B90/11 ,  A61B90/37 ,  A61B2017/00084 ,  A61B2017/00274 ,  A61B2017/3411 ,  A61B2018/00547 ,  A61B2090/378

摘要： The system for providing computer guided ablation of tissue of a patient includes an imaging device, an ablative surgical computer system, and a set of surgical devices. The imaging device receives imaging data from a treatment region of a patient, processes the imaging data and provides imaging output data and imaging signals. The imaging output data is available to an operator. The ablative surgical computer system includes a guidance module for processing the imaging signals and providing a treatment guidance plan to the operator; and, a treatment module for acquiring and processing surgical device output data, for optimally controlling treatment parameters and providing feedback information to the operator based on the treatment guidance plan. The set of surgical devices includes at least one integrated ablative/temperature sensing device including at least one ablative device for providing ablation of the treatment region based on the treatment parameters and operator input; and, at least one temperature sensing device for acquiring temperature data from the treatment region and providing a temperature sensing device output signal. The temperature sensing device output signal is a portion of the surgical device output data. The treatment guidance plan is utilized for placing the integrated ablative/temperature sensing device into the treatment region.

摘要翻译： 用于提供患者组织的计算机引导消融的系统包括成像装置，烧蚀外科手术计算机系统和一组手术装置。 成像装置从患者的治疗区域接收成像数据，处理成像数据并提供成像输出数据和成像信号。 成像输出数据可供操作员使用。 烧蚀手术计算机系统包括用于处理成像信号并向操作者提供治疗指导计划的引导模块; 以及用于获取和处理手术装置输出数据的治疗模块，用于根据治疗指导计划最佳地控制治疗参数并向操作者提供反馈信息。 该组手术装置包括至少一个集成的烧蚀/温度感测装置，其包括至少一个消融装置，用于基于治疗参数和操作员输入提供治疗区域的消融; 以及至少一个用于从处理区域获取温度数据并提供温度感测装置输出信号的温度感测装置。 温度感测装置输出信号是手术装置输出数据的一部分。 治疗指导计划用于将整合的烧蚀/温度感测装置放置在治疗区域中。

公开(公告)号：US06972014B2

公开(公告)日：2005-12-06

申请号：US10336322

申请日：2003-01-04

申请人： Jay J. Eum ,  Thach Duong

发明人： Jay J. Eum ,  Thach Duong

IPC分类号： A61B18/00 ,  A61B18/02 ,  A61B18/04 ,  A61B18/18

CPC分类号： A61B18/02 ,  A61B2018/00041 ,  A61B2018/046

摘要： Various embodiments of open system heat exchange catheters and methods of use are disclosed. The various catheters can be used with various ablative surgical devices. One specific exemplary use is in conjunction with cryosurgical probes involving ablation of the prostate, in which the integrity of the urethra is desired to be maintained. Other uses involve various heating ablative devices. In one embodiment an injection tube assembly is used to provide heat exchange fluid through the urethra to the bladder where it is then expelled via a suprapubic suction tube. In other embodiments a coaxial tube assembly is utilized which defines a passageway for either expelling the bladder fluid or for providing access to an endoscope. In other embodiments a double lumen assembly is utilized that defines a passageway for expelling bladder fluid.

摘要翻译： 公开了开放系统热交换导管和使用方法的各种实施例。 各种导管可以与各种烧蚀手术装置一起使用。 一个具体的示例性用途是结合涉及前列腺消融的冷冻手术探针，其中期望保持尿道的完整性。 其他用途涉及各种加热烧蚀装置。 在一个实施例中，注射管组件用于将热交换流体通过尿道提供给膀胱，然后通过耻骨上吸管将其排出。 在其它实施例中，使用同轴管组件，其限定用于排出膀胱流体或用于提供对内窥镜的通路的通道。 在其他实施例中，利用限定用于排出膀胱流体的通道的双腔组件。

公开(公告)号：US20080154253A1

公开(公告)日：2008-06-26

申请号：US12025619

申请日：2008-02-04

申请人： SANFORD D. DAMASCO ,  Thach Duong ,  Jawahar M. Ali ,  David J. Battles ,  Paul W. Mikus ,  Jay J. Eum

发明人： SANFORD D. DAMASCO ,  Thach Duong ,  Jawahar M. Ali ,  David J. Battles ,  Paul W. Mikus ,  Jay J. Eum

IPC分类号： A61B18/02

CPC分类号： A61B18/02 ,  A61B8/08 ,  A61B34/10 ,  A61B90/11 ,  A61B90/37 ,  A61B2017/00084 ,  A61B2017/00274 ,  A61B2017/3411 ,  A61B2018/00547 ,  A61B2090/378

摘要： The system for providing computer guided ablation of tissue of a patient includes an ablative surgical computer system and a set of surgical devices. The ablative surgical computer system includes a guidance module for providing a treatment guidance plan to an operator; and, a treatment module for acquiring and processing surgical device output data, for optimally controlling treatment parameters and providing feedback information to the operator based on the treatment guidance plan. The set of surgical devices includes at least one ablative device for providing ablation of the treatment region based on the treatment parameters and operator input; and, at least one temperature sensing device for acquiring temperature data from the treatment region and providing a temperature sensing device output signal. The temperature sensing device output signal is a portion of the surgical device output data. The treatment guidance plan is utilized for placing the ablative device and the temperature sensing device into the treatment region.

摘要翻译： 用于提供患者的组织的计算机引导消融的系统包括烧蚀性外科手术计算机系统和一组手术装置。 烧蚀外科计算机系统包括用于向操作者提供治疗指导计划的引导模块; 以及用于获取和处理手术装置输出数据的治疗模块，用于根据治疗指导计划最佳地控制治疗参数并向操作者提供反馈信息。 该组手术装置包括至少一个消融装置，用于基于治疗参数和操作员输入提供治疗区域的消融; 以及至少一个用于从处理区域获取温度数据并提供温度感测装置输出信号的温度感测装置。 温度感测装置输出信号是手术装置输出数据的一部分。 治疗指导计划用于将消融装置和温度感测装置放置在治疗区域中。

公开(公告)号：US20050043725A1

公开(公告)日：2005-02-24

申请号：US10954433

申请日：2004-09-30

申请人： Thach Duong ,  James Dinh

发明人： Thach Duong ,  James Dinh

IPC分类号： A61B17/00 ,  A61B18/02 ,  F25B9/02 ,  F28D7/10

CPC分类号： F25B9/02 ,  A61B18/02 ,  A61B2017/0046 ,  A61B2018/00041 ,  A61B2018/0262 ,  A61B2018/0293 ,  F28D7/106 ,  F28F2255/18

摘要： The threaded cryostat for a cryosurgical probe system includes an outer tube and a hollow elongated threaded element positioned within the outer tube. The threaded element has integral, external threads that extend from on an outer surface thereof. During operation a working fluid is transported in a first direction between a fluid supply line and a distal end of a cryosurgical probe within a first space defined within the threaded element. Working fluid is transported in a second direction between the distal end of the cryosurgical probe and the fluid supply line within a second space defined between the outer tube and the threaded element.

摘要翻译： 用于冷冻手术探针系统的螺纹低温恒温器包括外管和位于外管内的中空细长螺纹元件。 螺纹元件具有从其外表面延伸的整体的外螺纹。 在操作期间，工作流体在限定在螺纹元件内的第一空间内的流体供应管线和冷冻手术探针的远端之间沿第一方向输送。 在外管和螺纹元件之间限定的第二空间内，工作流体沿第二方向输送在冷冻外科探针的远端和流体供应管线之间。

公开(公告)号：US09381055B2

公开(公告)日：2016-07-05

申请号：US13942387

申请日：2013-07-15

申请人： Thach Duong ,  Min Frank Zeng ,  Peng Liu ,  Chaohua Xin

发明人： Thach Duong ,  Min Frank Zeng ,  Peng Liu ,  Chaohua Xin

IPC分类号： A61B18/02 ,  A61B18/00

CPC分类号： A61B18/02 ,  A61B2017/00323 ,  A61B2018/00101 ,  A61B2018/0022 ,  A61B2018/00285 ,  A61B2018/00577 ,  A61B2018/0212 ,  A61B2018/0287

摘要： A cryoablation system has a gas source which provides a working nitrogen gas at room temperature and at a constant set pressure, a liquid generator which is coupled to the gas source to receive the working gas, and which then generates a working cryogen fluid, and a catheter coupled to the liquid generator for receiving the working cryogen, the catheter having a distal section having a freezing element which delivers the working cryogen to a treatment location, the catheter also having a balloon positioned adjacent the distal section.

公开(公告)号：US07160291B2

公开(公告)日：2007-01-09

申请号：US10828031

申请日：2004-04-20

申请人： Sanford D. Damasco ,  Thach Duong

发明人： Sanford D. Damasco ,  Thach Duong

IPC分类号： A61B18/02

CPC分类号： F25B9/02 ,  A61B18/02 ,  A61B2017/0046 ,  A61B2018/00041 ,  A61B2018/0262 ,  A61B2018/0293 ,  F28D7/106 ,  F28F2255/18

摘要： A cryosurgical probe system includes a fluid supply line connectable at an inlet section to a source of cryogenic fluid; a fluid connector assembly securely connected to an outlet section of the fluid supply line for receiving fluid from the outlet section of the fluid supply line; and, a detachable cryosurgical probe detachably connectable to the fluid connector assembly. The cryosurgical probe system includes the capability of providing return fluid flow.

摘要翻译： 冷冻手术探针系统包括可在入口部分连接到低温流体源的流体供应管线; 流体连接器组件，其牢固地连接到流体供应管线的出口部分，用于从流体供应管线的出口部分接收流体; 以及可拆卸地连接到流体连接器组件的可拆卸冷冻手术探针。 冷冻手术探针系统包括提供回流流体的能力。

公开(公告)号：US20060264920A1

公开(公告)日：2006-11-23

申请号：US11430323

申请日：2006-05-09

申请人： Thach Duong

发明人： Thach Duong

IPC分类号： A61B18/02

CPC分类号： A61B18/02 ,  A61B2018/0262 ,  A61B2018/0293

摘要： The cryosurgical probe assembly with multiple deployable cryoprobes includes a) a housing assembly; b) a plurality of elongated structural support elements, each securely connected at a first end to the housing assembly; c) a tip member securely connected to second ends of the plurality of elongated structural support elements, the tip member including a plurality of cryoprobe openings; and, d) a plurality of cryoprobes each having a shaft thereon, each shaft being deployable through a respective cryoprobe opening during operation to a deployed position used for ablating tissue. In an alternate embodiment, a cylindrical housing is utilized rather than elongated structural support elements.

摘要翻译： 具有多个可展开冷冻探针的冷冻手术探针组件包括：a）壳体组件; b）多个细长结构支撑元件，每个细长结构支撑元件在第一端处牢固地连接到壳体组件; c）尖端构件，其牢固地连接到所述多个细长结构支撑元件的第二端，所述尖端构件包括多个冷冻探针开口; 以及d）多个各自具有轴的冷冻探针，每个轴可在操作期间通过相应的冷冻探针开口展开到用于烧蚀组织的展开位置。 在替代实施例中，使用圆柱形壳体而不是细长的结构支撑元件。

公开(公告)号：US20060015093A1

公开(公告)日：2006-01-19

申请号：US11231263

申请日：2005-09-20

申请人： Jay Eum ,  Thach Duong

发明人： Jay Eum ,  Thach Duong

IPC分类号： A61B18/02

CPC分类号： A61B18/02 ,  A61B2018/00041 ,  A61B2018/046

摘要： Various embodiments of open system heat exchange catheters and methods of use are disclosed. The various catheters can be used with various ablative surgical devices. One specific exemplary use is in conjunction with cryosurgical probes involving ablation of the prostate, in which the integrity of the urethra is desired to be maintained. Other uses involve various heating ablative devices. In one embodiment an injection tube assembly is used to provide heat exchange fluid through the urethra to the bladder where it is then expelled via a suprapubic suction tube. In other embodiments a coaxial tube assembly is utilized which defines a passageway for either expelling the bladder fluid or for providing access to an endoscope. In other embodiments a double lumen assembly is utilized that defines a passageway for expelling bladder fluid.

摘要翻译： 公开了开放系统热交换导管和使用方法的各种实施例。 各种导管可以与各种烧蚀手术装置一起使用。 一个具体的示例性用途是结合涉及前列腺消融的冷冻手术探针，其中期望保持尿道的完整性。 其他用途涉及各种加热烧蚀装置。 在一个实施例中，注射管组件用于将热交换流体通过尿道提供给膀胱，然后通过耻骨上吸管将其排出。 在其它实施例中，使用同轴管组件，其限定用于排出膀胱流体或用于提供对内窥镜的通路的通道。 在其他实施例中，利用限定用于排出膀胱流体的通道的双腔组件。

公开(公告)号：US20050192565A1

公开(公告)日：2005-09-01

申请号：US11116873

申请日：2005-04-28

申请人： Jay Eum ,  Thach Duong ,  Paul LaPine

发明人： Jay Eum ,  Thach Duong ,  Paul LaPine

IPC分类号： A61B17/00 ,  A61B18/02

CPC分类号： A61B18/02 ,  A61B2017/0046 ,  A61B2018/0262

摘要： The detachable cryosurgical probe includes a disposable probe assembly and a reusable probe assembly. The disposable probe assembly includes a breakaway collar which, when twisted away, activates a finger lock element which provides release of the disposable probe assembly from the reusable probe assembly. Additional features include a safety valve assembly for impeding cryogenic working fluid flow when the disposable probe assembly is detached from the reusable probe assembly and an electrical confirmation assembly for providing electrical confirmation that the disposable probe assembly is connected. Other embodiments include a sliding mechanism that allows for selectively positioning of the vacuum tube relative to the shaft to create an ice ball of the desired size and configuration.

摘要翻译： 可拆卸的冷冻手术探针包括一次性探针组件和可重复使用的探针组件。 一次性探针组件包括分离套环，当被扭转时，该开口套环激活手指锁定元件，其提供一次性探针组件从可重复使用的探针组件的释放。 另外的特征包括一个安全阀组件，用于当一次性探头组件与可重复使用的探头组件分离时阻止低温工作流体流动;以及电气确认组件，用于提供一次性探头组件连接的电气确认。 其它实施例包括允许真空管相对于轴选择性定位以产生所需尺寸和构造的冰球的滑动机构。