公开(公告)号：US20240180611A1

公开(公告)日：2024-06-06

申请号：US18408689

申请日：2024-01-10

申请人： Boston Scientific Scimed, Inc.

发明人： Thomas John Herbst ,  Mark W. Boden ,  Sandra Nagale

IPC分类号： A61B18/14 ,  A61B18/00 ,  A61B18/02 ,  A61B18/18 ,  A61B18/20 ,  A61N7/02

CPC分类号： A61B18/1485 ,  A61B18/1477 ,  A61B18/1492 ,  A61B2018/00434 ,  A61B2018/00517 ,  A61B2018/00577 ,  A61B2018/00595 ,  A61B2018/0293 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1475 ,  A61B18/1815 ,  A61B18/20 ,  A61N7/022 ,  A61N2007/025

摘要： In one aspect, the present disclosure is directed to methods of treating various conditions including bladder conditions in a patient, comprising: positioning at least one ablative element of an ablative device on or over an adventitial surface of the bladder; and using the ablative device to denervate bladder nerve fibers. Other aspects of the present disclosure pertain, for example, to devices and kits for of treating bladder conditions.

公开(公告)号：US11963706B2

公开(公告)日：2024-04-23

申请号：US16440798

申请日：2019-06-13

申请人： Pacira CryoTech, Inc.

发明人： Lisa Elkins ,  Ronald Williams

IPC分类号： A61B18/02 ,  A61M37/00 ,  A61B17/00 ,  A61B18/00 ,  A61B18/14 ,  A61M5/44

CPC分类号： A61B18/02 ,  A61M37/0015 ,  A61B2017/00747 ,  A61B2017/00792 ,  A61B2018/00023 ,  A61B2018/00029 ,  A61B2018/00041 ,  A61B2018/00434 ,  A61B2018/00452 ,  A61B2018/00464 ,  A61B2018/025 ,  A61B2018/0262 ,  A61B2018/0293 ,  A61B18/14 ,  A61M5/44 ,  A61M2037/0023 ,  A61M2037/003

摘要： Devices, systems, and methods treat cosmetic defects, and often apply cooling with at least one tissue-penetrating probe inserted through of the skin of a patient. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments of the cooling treatments will interfere with the nerve/muscle contractile function chain so as to mitigate wrinkles of the skin. Related treatments may be used therapeutically for treatment of back and other muscle spasms, chronic pain, and the like. Some embodiments may remodel subcutaneous adipose tissue so as to alter a shape or appearance of the skin surface.

公开(公告)号：US11937870B2

公开(公告)日：2024-03-26

申请号：US17192870

申请日：2021-03-04

申请人： May Health US Inc.

发明人： Denise Zarins ,  Neil Barman ,  Garrett Schwab ,  Roger Osborne ,  Douglas Sutton

IPC分类号： A61B18/12 ,  A61B8/08 ,  A61B8/12 ,  A61B18/14 ,  A61F6/20 ,  A61B8/00 ,  A61B17/00 ,  A61B17/22 ,  A61B17/34 ,  A61B17/42 ,  A61B18/00 ,  A61B18/02 ,  A61B18/04 ,  A61B18/06 ,  A61B18/16 ,  A61B18/22 ,  A61B90/00 ,  A61N7/00 ,  A61N7/02

CPC分类号： A61B18/1485 ,  A61B8/0841 ,  A61B8/085 ,  A61B8/12 ,  A61B18/1482 ,  A61F6/20 ,  A61B8/4427 ,  A61B8/4433 ,  A61B2017/00278 ,  A61B2017/003 ,  A61B2017/00455 ,  A61B17/22004 ,  A61B2017/3405 ,  A61B2017/3413 ,  A61B17/42 ,  A61B2017/4233 ,  A61B2018/00196 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00559 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00595 ,  A61B2018/00642 ,  A61B2018/00702 ,  A61B2018/0072 ,  A61B2018/00726 ,  A61B2018/00732 ,  A61B2018/00744 ,  A61B2018/00767 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00982 ,  A61B2018/0293 ,  A61B2018/048 ,  A61B18/06 ,  A61B18/1206 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1475 ,  A61B18/16 ,  A61B18/22 ,  A61B2090/378 ,  A61B2090/3925 ,  A61B2090/3966 ,  A61N2007/0043 ,  A61N7/02 ,  A61N7/022

摘要： Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.

公开(公告)号：US11925403B2

公开(公告)日：2024-03-12

申请号：US17046873

申请日：2019-04-12

申请人： Piedmont Medsystems (Zhuhai) Co., Ltd.

发明人： Jiahua Xiao ,  Alan De La Rama ,  Cary Kunihiko Hata

IPC分类号： A61B18/02 ,  A61B18/00

CPC分类号： A61B18/02 ,  A61B2018/00023 ,  A61B2018/00041 ,  A61B2018/00101 ,  A61B2018/0022 ,  A61B2018/00255 ,  A61B2018/00261 ,  A61B2018/00351 ,  A61B2018/00375 ,  A61B2018/00577 ,  A61B2018/0212 ,  A61B2018/025 ,  A61B2018/0293

摘要： A cryoablation catheter, including a first capsule body, a core tube and a heat insulation part, wherein the first capsule body is mounted at a front end of the core tube, and has a front end area adapted for fitting to myocardial tissue during a cryoablation process and a rear end area exposed to blood; the core tube has a first looping path provided therein which is adapted for a first fluid with low temperature to be filled into or flow out of the first capsule body; the heat insulation part is at least partially fitting to the rear end area, and is adapted for reducing heat exchange efficiency between the first fluid and the blood in an atrium. The cryoablation operating apparatus and the cryoablation equipment thereof can effectively reduce the heat exchange between the cryoablation catheter and the blood during a cryoablation process.

公开(公告)号：US11890134B2

公开(公告)日：2024-02-06

申请号：US17084141

申请日：2020-10-29

申请人： Gynesonics, Inc.

发明人： Michael A. Munrow ,  Darrin Uecker ,  Brian Placek ,  Harry Kwan ,  David Toub ,  Cameron D. Hinman ,  David J. Danitz

IPC分类号： A61B8/08 ,  A61B18/14 ,  A61B8/00 ,  A61B8/12 ,  A61B34/00 ,  A61B5/06 ,  A61B18/04 ,  A61B18/18 ,  A61B18/02 ,  A61B18/00 ,  A61N7/02 ,  A61B34/10 ,  A61B34/20 ,  A61B90/00 ,  A61B8/14

CPC分类号： A61B8/0841 ,  A61B5/066 ,  A61B8/12 ,  A61B8/445 ,  A61B8/463 ,  A61B18/1477 ,  A61B34/25 ,  A61B8/145 ,  A61B8/461 ,  A61B8/467 ,  A61B18/02 ,  A61B18/042 ,  A61B18/1485 ,  A61B18/1815 ,  A61B90/04 ,  A61B2018/00559 ,  A61B2018/00577 ,  A61B2018/00702 ,  A61B2018/00761 ,  A61B2018/00898 ,  A61B2018/00904 ,  A61B2018/00982 ,  A61B2018/0293 ,  A61B2018/143 ,  A61B2018/1475 ,  A61B2034/104 ,  A61B2034/107 ,  A61B2034/2063 ,  A61B2034/254 ,  A61B2090/034 ,  A61B2090/0427 ,  A61B2090/378 ,  A61B2090/3782 ,  A61B2090/3784 ,  A61N2007/025 ,  F04C2270/041

摘要： A system for deploying needles in tissue includes a controller and a visual display. A treatment probe has both a needle and tines deployable from the needle which may be advanced into the tissue. The treatment probe also has adjustable stops which control the deployed positions of both the needle and the tines. The adjustable stops are coupled to the controller so that the virtual treatment and safety boundaries resulting from the treatment can be presented on the visual display prior to actual deployment of the system.

公开(公告)号：US11865038B2

公开(公告)日：2024-01-09

申请号：US17571307

申请日：2022-01-07

申请人： Pacira CryoTech, Inc.

发明人： Jwala Karnik ,  John Allison ,  Clint Carnell

IPC分类号： A61B18/02 ,  A61F7/12 ,  A61M5/00 ,  A61N1/40 ,  A61B18/00 ,  A61B18/14 ,  A61F7/02 ,  A61F7/00

CPC分类号： A61F7/12 ,  A61B18/02 ,  A61M5/00 ,  A61N1/403 ,  A61B2018/00041 ,  A61B2018/00434 ,  A61B2018/0293 ,  A61B2018/1425 ,  A61F2007/0042 ,  A61F2007/0087 ,  A61F2007/0285 ,  A61M2202/0484 ,  A61M2210/086

摘要： A method in which a nerve associated with a spasticity in a limb of a patient may be identified. The cryogenic cooling needle may be inserted through a skin surface. The cryogenic cooling needle may be positioned to a target tissue such that the distal end of the cryogenic cooling needle is proximate to the nerve by bending the needle, wherein the needle has varying stiffness at a proximal portion and a distal portion. A treatment cycle may be delivered to a target tissue proximate to the nerve, the treatment cycle may comprise a cooling phase wherein cooling fluid flows into the lumen so that liquid from the cooling fluid flow vaporizes within the lumen to provide cooling to the nerve so as to treat spasticity.

公开(公告)号：US20230404642A1

公开(公告)日：2023-12-21

申请号：US18204779

申请日：2023-06-01

申请人： SYNCROMUNE, INC.

发明人： Charles J. Link, JR. ,  Jason R. Williams ,  Mario R. Mautino ,  Daniel K. Recinelia ,  Eamonn P. Hobbs

IPC分类号： A61B18/02 ,  C07K16/28 ,  C07K14/00 ,  A61P35/00

CPC分类号： A61B18/02 ,  C07K16/2878 ,  C07K16/2818 ,  C07K14/001 ,  A61P35/00 ,  A61B2018/0293 ,  A61K2039/507

摘要： The present disclosure provides, among other things, methods of cancer treatment comprising steps of: a) intratumoral cell lysis, mediated by cryolysis; and b) intratumoral administration of 1) a combination of immunotherapeutic agents comprising: i) a TLR9 agonist CpG oligodeoxydinucleotide, ii) an agonistic anti-CD40 monoclonal antibody, iii) an agonistic anti-OX40 monoclonal antibody and iv) an anti-CTLA4 monoclonal antibody; or 2) a combination of immunotherapeutic agents comprising: i) a TLR9 agonist CpG oligodeoxydinucleotide, ii) an agonistic anti-CD40 monoclonal antibody, iii) an anti-PD1 monoclonal antibody and iv) an anti-CTLA4 monoclonal antibody.

公开(公告)号：US11844560B2

公开(公告)日：2023-12-19

申请号：US18008465

申请日：2022-06-02

申请人： HYGEA MEDICAL TECHNOLOGY CO., LTD.

发明人： Chen Chi ,  Qianfu Huang

IPC分类号： A61B18/02 ,  A61B34/10 ,  A61B18/00

CPC分类号： A61B18/02 ,  A61B2018/00577 ,  A61B2018/0293 ,  A61B2034/104 ,  A61B2034/107

摘要： The disclosure relates to a path planning device for multi-probe joint cryoablation, the device comprising a memory and a processor. The memory stores a computer program, and the processor, when executing the computer program, implements the following steps: acquiring a target region in a medical scanned image of a target object and corresponding to a target tissue to be cryoablated; selecting a single-probe ablation region from the target region; for the single-probe ablation region, obtaining a puncture path of single-probe cryoablation and a corresponding ice ball coverage region; and if the ice ball coverage region does not completely cover target region, then taking the remaining region of the target region from which the ice ball coverage region is excluded as a new target region, and returning to the step of selecting the selecting the single-probe ablation region from the target region.

公开(公告)号：US20230338076A1

公开(公告)日：2023-10-26

申请号：US17799471

申请日：2019-12-13

申请人： HYGEA MEDICAL TECHNOLOGY CO., LTD.

发明人： Fuliang Luo ,  Cuihu Liu ,  Bowei Chen ,  Wensheng Wei ,  Jian Xiao ,  Jingjing Yang

IPC分类号： A61B18/02 ,  A61B18/04

CPC分类号： A61B18/02 ,  A61B18/04 ,  A61B2018/0293 ,  A61B2018/046 ,  A61B2018/00577

摘要： A high and low temperature composite ablation surgery system, relating to the technical field of cryotherapy, used to improve the safety and effectiveness of therapy, and comprising a main unit (100) and a cryogenic-thermal ablation probe (200) connected to the main unit (100). The main unit (100) comprises a cold working medium supply system (300), a hot working medium supply system (400), and a working medium distribution system (500). The working medium distribution system (500) can respectively control the cold working medium supply system (300) to deliver a cold working medium to the cryogenic-thermal ablation probe (200) and control the hot working medium supply system (400) to deliver a hot working medium to the cryogenic-thermal ablation probe (200). Therefore, after low-temperature therapy is completed, a therapy area can be quickly rewarmed, thereby providing a basis for improving the safety, economy and convenience of the surgery.

公开(公告)号：US11786307B2

公开(公告)日：2023-10-17

申请号：US16566654

申请日：2019-09-10

申请人： CANON U.S.A., INC.

发明人： Barret Daniels

IPC分类号： A61B34/10 ,  A61B90/11 ,  A61B18/02 ,  A61B90/00 ,  A61B34/00 ,  A61B18/00

CPC分类号： A61B34/10 ,  A61B18/02 ,  A61B34/25 ,  A61B90/11 ,  A61B90/37 ,  A61B90/39 ,  A61B2018/0022 ,  A61B2018/00577 ,  A61B2018/0212 ,  A61B2018/0293 ,  A61B2034/107 ,  A61B2090/363 ,  A61B2090/3762 ,  A61B2090/3937

摘要： One or more devices, systems, methods and storage mediums for performing medical procedure (e.g., needle guidance, ablation, biopsy, etc.) planning and/or performance, and/or for performing visualization and manipulation of registration result(s), are provided. Examples of applications for such devices, systems, methods and storage mediums include imaging, evaluating and diagnosing biological objects, such as, but not limited to, lesions and tumors, and such devices, systems, methods and storage mediums may be used for radiotherapy applications (e.g., to determine whether to place seed(s) for radiotherapy). The devices, systems, methods and storage mediums provided herein provide improved registration results by providing one or more of the following: automatic multi-planar reconstruction of a device fiducial plane, automatic multi-planar reconstruction of an oblique fiducial slice and on-the-fly update(s) of template matching and registration error calculations based on user manipulation of detected fiducial locations.