公开(公告)号：US10113199B2

公开(公告)日：2018-10-30

申请号：US14282837

申请日：2014-05-20

申请人： British Columbia Cancer Agency Branch

发明人： Ryan D. Morin ,  Marco A. Marra ,  Andrew J. Mungall ,  Martin Hirst ,  Maria Mendez-Lago ,  Randy D. Gascoyne ,  Joseph M. Connors

IPC分类号： C12Q1/68 ,  C12Q1/6886 ,  G01N33/574 ,  C07K14/705 ,  G01N33/50

摘要： The disclosure provides a method of identifying a subject as having B-cell non-Hodgkin lymphoma (NHL) such as testing a sample from a subject for a mutation in one or more biomarkers. Also described are methods of classifying or monitoring a subject having, or suspected of having, B-cell non-Hodgkin lymphoma comprising testing the same for a mutation in one or more biomarkers.

公开(公告)号：US20140342920A1

公开(公告)日：2014-11-20

申请号：US14282837

申请日：2014-05-20

申请人： British Columbia Cancer Agency Branch

发明人： Ryan D. Morin ,  Marco A. Marra ,  Andrew J. Mungall ,  Martin Hirst ,  Maria Mendez-Lago ,  Randy D. Gascoyne ,  Joseph M. Connors

IPC分类号： C12Q1/68 ,  C07K14/705 ,  G01N33/574

CPC分类号： C12Q1/6886 ,  C07K14/705 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/156 ,  G01N33/57407 ,  G01N33/57426

摘要： The disclosure provides a method of identifying a subject as having B-cell non-Hodgkin lymphoma (NHL) such as testing a sample from a subject for a mutation in one or more biomarkers. Also described are methods of classifying or monitoring a subject having, or suspected of having, B-cell non-Hodgkin lymphoma comprising testing the same for a mutation in one or more biomarkers.

摘要翻译： 本公开提供了将受试者鉴定为具有B细胞非霍奇金淋巴瘤（NHL）的方法，例如测试来自受试者的样品用于一种或多种生物标志物中的突变。 还描述了对具有或怀疑具有B细胞非霍奇金淋巴瘤的受试者进行分类或监测的方法，包括测试其在一种或多种生物标志物中的突变。

公开(公告)号：US20140024099A1

公开(公告)日：2014-01-23

申请号：US13945439

申请日：2013-07-18

申请人： British Columbia Cancer Agency Branch

发明人： Ryan D. Morin ,  Marco A. Marra ,  Randy D. Gascoyne ,  Joseph M. Connors

IPC分类号： C12Q1/68 ,  C12N9/10

CPC分类号： C12Q1/6886 ,  C07K16/40 ,  C12N9/1007 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Y201/01043 ,  G01N33/57407 ,  G01N33/6872 ,  G01N2800/52

摘要： The disclosure provides a method of identifying a subject as having B-cell non-Hodgkin lymphoma (NHL) such as testing a sample from a subject for a mutation in one or more biomarkers. Also described are methods for classifying or monitoring a subject having, or suspected of having, B-cell non-Hodgkin lymphoma comprising testing the sample for a mutation in one or more biomarkers.

摘要翻译： 本公开提供了将受试者鉴定为具有B细胞非霍奇金淋巴瘤（NHL）的方法，例如测试来自受试者的样品用于一种或多种生物标志物中的突变。 还描述了用于分类或监测具有或怀疑具有B细胞非霍奇金淋巴瘤的受试者的方法，包括测试样品中一种或多种生物标志物中的突变。

公开(公告)号：US20130195843A1

公开(公告)日：2013-08-01

申请号：US13839597

申请日：2013-03-15

申请人： British Columbia Cancer Agency Branch

发明人： Ryan D. Morin ,  Marco A. Marra ,  Andrew J. Mungall ,  Martin Hirst ,  Maria Mendez-Lago ,  Randy D. Gascoyne ,  Joseph M. Connors

IPC分类号： C12Q1/68 ,  C07K16/40 ,  G01N33/68 ,  C12N9/10

CPC分类号： C12Q1/6886 ,  C07K16/40 ,  C12N9/1007 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Y201/01043 ,  G01N33/57407 ,  G01N33/6872 ,  G01N2800/52

摘要： The disclosure provides a method of identifying a subject as having B-cell non-Hodgkin lymphoma (NHL) such as testing a sample from a subject for a mutation in one or more biomarkers. Also described are methods for classifying or monitoring a subject having, or suspected of having, B-cell non-Hodgkin lymphoma comprising testing the sample for a mutation in one or more biomarkers.

摘要翻译： 本公开提供了将受试者鉴定为具有B细胞非霍奇金淋巴瘤（NHL）的方法，例如测试来自受试者的样品用于一种或多种生物标志物中的突变。 还描述了用于分类或监测具有或怀疑具有B细胞非霍奇金淋巴瘤的受试者的方法，包括测试样品中一种或多种生物标志物中的突变。