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    Methods and compositions for alleviating stuttering
    11.
    发明申请
    Methods and compositions for alleviating stuttering 有权
    减轻口吃的方法和成分

    公开(公告)号：US20050256029A1

    公开(公告)日：2005-11-17

    申请号：US11046706

    申请日：2005-02-01

    申请人： John Murphy ,  Kay D'Orlando

    发明人： John Murphy ,  Kay D'Orlando

    IPC分类号： A61K31/44 ,  A61K38/17 ,  A61K31/473 ,  A61K31/4745 ,  A61K31/515 ,  A61K31/5513 ,  A61K31/573

    CPC分类号： A61K31/44

    摘要： Methods of treating stuttering include treating people with gamma-aminobutyric acid (GABA) receptor modulators, including cyclopyrrolones. A second active agent may be used with GABA receptor modulators. Active enantiomers, active metabolites, and pharmaceutically acceptable salts of gamma-aminobutyric acid receptor modulators, including cyclopyrrolones, are acceptable components of the compositions. The cyclopyrrolone class of modulators includes pagoclone, suriclone, zopiclone, 2-(7-chloro-2-naphthyridin-1,8-yl)-3-(5-methyl-2-oxohexyl)isoindolin-1-one, 2-(7-chloro-2-naphthyridin-1,8-yl)isoindolin-1-yl-4-acetamidobutyrate, and 2-(7-chloro-1,8-naphthyridin-2yl)-3-(5-methyl-5-hydroxy-2-oxohexyl)-1-isoindolinone.

    摘要翻译： 治疗口吃的方法包括用γ-氨基丁酸（GABA）受体调节剂治疗人，包括环吡咯啉酮。 第二种活性剂可与GABA受体调节剂一起使用。 γ-氨基丁酸受体调节剂（包括环吡咯烷酮）的活性对映异构体，活性代谢物和药学上可接受的盐是组合物的可接受组分。 环吡咯酮类的调节剂包括：幽门螺旋体，西洛酮，佐匹克隆，2-（7-氯-2-萘啶-1,8-基）-3-（5-甲基-2-氧代己基）异二氢吲哚-1-酮，2-（ 7-氯-2-萘啶-1,8-基）异二氢吲哚-1-基-4-乙酰氨基丁酸酯和2-（7-氯-1,8-二氮杂萘-2-基）-3-（5-甲基-5- 羟基-2-氧代己基）-1-异二氢吲哚酮。

    Method and apparatus for communicating between a network workstation and an internet
    12.
    发明授权
    Method and apparatus for communicating between a network workstation and an internet 失效
    用于在网络工作站和互联网之间通信的方法和装置

    公开(公告)号：US5867660A

    公开(公告)日：1999-02-02

    申请号：US439136

    申请日：1995-05-11

    申请人： Jonathan Schmidt ,  Lewis Donzis ,  Henry Donzis ,  John Murphy ,  Peter Baron

    发明人： Jonathan Schmidt ,  Lewis Donzis ,  Henry Donzis ,  John Murphy ,  Peter Baron

    IPC分类号： H04L29/06 ,  H04L29/08 ,  G06F13/00

    CPC分类号： H04L29/06 ,  H04L69/161 ,  H04L69/162 ,  H04L67/42 ,  H04L69/16 ,  H04L69/32

    摘要： An apparatus and method for connecting a plurality of LAN workstations to the internet via an on-line server/interface that does not require a PC operating system dedicated to the server. The server operates in TCP/IP protocol for communication over the Internet. Only a single connection to the Internet is required in order to permit the entire LAN to operate simultaneously on the Internet. Specifically, only a single phone line is required to simultaneously serve all LAN workstations. The system is equally well suited to connect via a telephone line connection to an Internet providers's slip or PPP or via an Ethernet connection to a router or direct connection by any available means. The system does not disturb the native LAN protocol, while communicating via the internet protocol such as, by way of example, TCP/IP. The LAN is provided with a complete internet protocol service, supporting functions not generally available in the dedicated stacks previously provided for individual PCs.

    摘要翻译： 一种用于通过不需要专用于服务器的PC操作系统的在线服务器/接口将多个LAN工作站连接到因特网的装置和方法。 服务器以TCP / IP协议运行，用于通过Internet进行通信。 为了允许整个局域网在互联网上同时运行，只需要连接到互联网的单一连接。 具体来说，只需要一条电话线即可同时为所有LAN工作站提供服务。 该系统同样适合通过电话线路连接到互联网供应商的单据或PPP，或通过以太网连接到路由器或通过任何可用的方式进行直接连接。 当通过例如TCP / IP的网络协议进行通信时，该系统不会干扰本地LAN协议。 LAN提供完整的互联网协议服务，支持以前为个人PC提供的专用堆栈中通常不可用的功能。

    Interspinous internal fixation/distraction device
    13.
    发明授权
    Interspinous internal fixation/distraction device 有权
    椎间内固定/牵引装置

    公开(公告)号：US08690921B2

    公开(公告)日：2014-04-08

    申请号：US13493630

    申请日：2012-06-11

    申请人： James W. Dwyer ,  John Murphy

    发明人： James W. Dwyer ,  John Murphy

    IPC分类号： A61B17/70

    CPC分类号： A61B17/7067 ,  A61B17/7062 ,  A61B17/7068

    摘要： Disclosed are an apparatus for an interspinous fixation and/or distraction of vertebrae and a methodology for minimally invasive implantation of the apparatus in the spine of a patient. The apparatus corresponds to a pair of teardrop shaped lateral wing elements spaced apart by a central core element that may be selectively sized during the implantation process. The wings and central core are held together by a single threaded bolt and locking nut configuration resulting in a simple structure that may be easily implanted with minimal patient discomfort.

    摘要翻译： 公开了一种用于椎间棘突固定和/或牵引椎体的装置以及用于在患者脊柱中微创植入该装置的方法。 该装置对应于由中心芯元件间隔开的一对泪滴形侧翼元件，其可以在植入过程期间选择性地定尺寸。 翼和中心芯通过单个螺栓和锁定螺母构造保持在一起，导致简单的结构，其可以容易地植入，患者的不适最小。

    MAPPING SYSTEM AND METHOD
    17.
    发明申请
    MAPPING SYSTEM AND METHOD 审中-公开
    映射系统和方法

    公开(公告)号：US20090112461A1

    公开(公告)日：2009-04-30

    申请号：US12100941

    申请日：2008-04-10

    申请人： John Murphy

    发明人： John Murphy

    IPC分类号： G01C21/30

    CPC分类号： G01C21/20

    摘要： A mapping method is presented comprising receiving travel-related information from a user. A user interface is presented displaying at least a portion of a transportation hub. The user interface indicates a path and an estimated travel time from a current location within the transportation hub to a target location within the transportation hub using the received travel-related information.

    摘要翻译： 提出了一种映射方法，其包括从用户接收旅行相关信息。 呈现显示交通枢纽的至少一部分的用户界面。 用户界面使用所接收的旅行相关信息来指示从交通枢纽内的当前位置到交通枢纽内的目标位置的路径和估计行驶时间。

    Method and apparatus for incremental computation of the accuracy of a categorization-by-example system
    20.
    发明授权
    Method and apparatus for incremental computation of the accuracy of a categorization-by-example system 有权
    逐个分类示例系统的精度的增量计算方法和装置

    公开(公告)号：US07089238B1

    公开(公告)日：2006-08-08

    申请号：US09893301

    申请日：2001-06-27

    申请人： Mark W. Davis ,  John Murphy ,  Clark Leonard Breyman

    发明人： Mark W. Davis ,  John Murphy ,  Clark Leonard Breyman

    IPC分类号： G06F17/30

    CPC分类号： G06F17/3071 ,  Y10S707/99935

    摘要： Disclosed are methods and for incrementally updating the accuracy provided by documents in training set of used for automatic categorization. A k-nearest neighbor database includes the documents in the training set, categories, category assignments of the documents and category scores for the documents. A list made up of the nearest neighbors of the documents and corresponding similarity scores contains is maintained by the method. On adding or deleting documents or category assignments, the documents influenced by the changed documents or category assignments are identified. The category scores of the identified documents are updated to be consistent for the updated training set and a new precision and recall curves are computed for the categories including updated category scores. The precision and recall curves may be used to determine an optimal number of documents to maximize the return of relevant documents while minimizing the total number of documents.

    摘要翻译： 公开了用于逐步更新用于自动分类的训练集中的文档提供的准确性的方法和方法。 k最近邻数据库包括培训集中的文档，文档的类别分类和文档的类别分数。 由该方法维护由文档的最近邻居组成的列表和相应的相似性得分包含的列表。 在添加或删除文档或类别分配时，确定受更改文档或类别分配影响的文档。 识别的文档的类别分数被更新为对于更新的训练集合是一致的，并且对于包括更新的分类分数的类别计算新的精确度和回忆曲线。 精度和回忆曲线可用于确定文档的最佳数量以最大限度地返回相关文档，同时最小化文档的总数。