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19 条记录 (耗时 0.029 秒)

    GRAFT COPOLYMER WITH PH DEPENDENT BEHAVIOUR
    13.
    发明申请
    GRAFT COPOLYMER WITH PH DEPENDENT BEHAVIOUR 有权
    具有PH依赖性行为的GRAFT共聚物

    公开(公告)号：US20130059986A1

    公开(公告)日：2013-03-07

    申请号：US13582828

    申请日：2011-03-09

    申请人： Ramesh Muthusamy ,  Mohan Gopalkrishna

    发明人： Ramesh Muthusamy ,  Mohan Gopalkrishna

    IPC分类号： C08G63/91

    CPC分类号： C08F283/01 ,  C08F226/06

    摘要： A graft copolymer with pH dependent behavior of formula 1 Comprises, (i) a backbone having the formula 1 [A(x) B(Y) C(z)] wherein (A) is diol, (B) is dicarboxylic acid or acid anhydride and (C) is monomer containing pendent unsaturation such that (x)=41-45%, (y)=49-53% (z)=4-7% by mole; and (ii) a graft which is a polymer of the basic monomer (D) which comprises “w” weight percent of the total weight of said graft copolymer such that ‘w’ is 22-52%. The graft copolymers do not swell/dissolve at neutral and basic pH and swell/dissolve at acidic pH. The polymers are useful as protective coating for pharmaceutical dosage forms and as excipient in the development of extended release drug delivery systems.

    摘要翻译： 具有式1的pH依赖行为的接枝共聚物包括：（i）具有式1 [A（x）B（Y）C（z）]的骨架，其中（A）是二醇，（B）是二羧酸或酸 酸酐和（C）是含有不饱和键的单体，使得（x）= 41-45％，（y）= 49-53％（z）= 4-7摩尔％ 和（ii）作为碱性单体（D）的聚合物的接枝物，其包含占所述接枝共聚物总重量的重量百分比，使得w为22-52％。 接枝共聚物在中性和碱性pH下不溶胀/溶胀，并在酸性pH下溶胀/溶解。 这些聚合物可用作药物剂型的保护性涂层和作为延长释放药物递送系统开发中的赋形剂。

    PH SENSITIVE GRAFT COPOLYMER
    14.
    发明申请
    PH SENSITIVE GRAFT COPOLYMER 有权
    PH敏感共聚物

    公开(公告)号：US20120059131A1

    公开(公告)日：2012-03-08

    申请号：US13254630

    申请日：2010-03-05

    申请人： Ramesh Muthusamy ,  Mohan Gopalkrishna Kulkarni

    发明人： Ramesh Muthusamy ,  Mohan Gopalkrishna Kulkarni

    IPC分类号： C08F283/02

    CPC分类号： C08F283/01 ,  C08F220/06

    摘要： Graft copolymer (P) which exhibit pH dependent swelling/dissolution properties comprising a hydrophobic back-bone and graft chains comprising acidic monomer. This Graft copolymer (P) do not swell or dissolve at acidic pH prevalent in the stomach and they swell/dissolve at near neutral pH prevalent in the intestinal region. The graft copolymer (P) is useful for the development of drug delivery formulations particularly for oral drug delivery formulations.

    摘要翻译： 表现出pH依赖性溶胀/溶解性能的接枝共聚物（P），其包含疏水性背骨和包含酸性单体的接枝链。 这种接枝共聚物（P）在胃中普遍存在的酸性pH下不溶胀或溶解，并且它们在肠道中普遍存在的接近中性pH下溶胀/溶解。 接枝共聚物（P）可用于开发特别用于口服药物递送制剂的药物递送制剂。

    Graft copolymer with pH dependent behaviour
    15.
    发明授权
    Graft copolymer with pH dependent behaviour 有权
    具有pH依赖性的接枝共聚物

    公开(公告)号：US09012574B2

    公开(公告)日：2015-04-21

    申请号：US13582828

    申请日：2011-03-09

    申请人： Ramesh Muthusamy ,  Mohan Gopalkrishna Kulkarni

    发明人： Ramesh Muthusamy ,  Mohan Gopalkrishna Kulkarni

    IPC分类号： C08G63/91 ,  C08F283/01

    CPC分类号： C08F283/01 ,  C08F226/06

    摘要： A graft copolymer with pH dependent behavior of formula 1 Comprises, (i) a backbone having the formula 1 [A(X)B(Y)C(z)] wherein (A) is diol, (B) is dicarboxylic acid or acid anhydride and (C) is monomer containing pendent unsaturation such that (x)=41-45%, (y)=49-53% (z)=4-7% by mole; and (ii) a graft which is a polymer of the basic monomer (D) which comprises “w” weight percent of the total weight of said graft copolymer such that ‘w’ is 22-52%. The graft copolymers do not swell/dissolve at neutral and basic pH and swell/dissolve at acidic pH. The polymers are useful as protective coating for pharmaceutical dosage forms and as excipient in the development of extended release drug delivery systems.

    摘要翻译： 具有式1的pH依赖性行为的接枝共聚物包括：（i）具有式1 [A（X）B（Y）C（z）]的骨架，其中（A）是二醇，（B）是二羧酸或酸 酸酐和（C）是含有不饱和键的单体，使得（x）= 41-45％，（y）= 49-53％（z）= 4-7摩尔％ 和（ii）作为碱性单体（D）的聚合物的接枝物，其包含所述接枝共聚物总重量的“w”重量百分比，使得“w”为22-52％。 接枝共聚物在中性和碱性pH下不溶胀/溶胀，并在酸性pH下溶胀/溶解。 这些聚合物可用作药物剂型的保护性涂层和作为延长释放药物递送系统开发中的赋形剂。

    WATER-BASED DRILLING FLUID WITH CYCLODEXTRIN SHALE STABILIZER
    17.
    发明申请
    WATER-BASED DRILLING FLUID WITH CYCLODEXTRIN SHALE STABILIZER 有权
    基于水的钻井液与CYCLODEXTRIN SHALE STABILIZER

    公开(公告)号：US20140128295A1

    公开(公告)日：2014-05-08

    申请号：US13670636

    申请日：2012-11-07

    申请人： Vikrant Bhavanishankar Wagles ,  Dhanashree Gajanan Kulkarni ,  Ramesh Muthusamy

    发明人： Vikrant Bhavanishankar Wagles ,  Dhanashree Gajanan Kulkarni ,  Ramesh Muthusamy

    IPC分类号： C09K8/10

    CPC分类号： C09K8/10 ,  C09K8/032 ,  C09K8/08 ,  C09K8/12 ,  C09K8/5758 ,  C09K2208/12

    摘要： Well fluids and methods are provided that can be used for stabilizing a shale formation, especially during drilling of a well into or through a shale formation. The well fluids include: (i) a continuous water phase; (ii) a viscosity-increasing agent, wherein the viscosity-increasing agent comprises water-soluble hydrophilic polymer; (iii) a fluid loss control agent; and (iv) a cyclodextrin-based compound. The methods of drilling include the steps of: (A) introducing the well fluid into a zone of a subterranean formation; and (b) drilling the zone.

    摘要翻译： 提供了可用于稳定页岩形成的井液和方法，特别是在将钻井钻入或通过页岩层时。 井液包括：（i）连续水相; （ii）粘度增加剂，其中增粘剂包括水溶性亲水聚合物; （iii）流失控制剂; 和（iv）环糊精类化合物。 钻井方法包括以下步骤：（A）将井流体引入地下岩层的区域; 和（b）钻孔区域。