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公开(公告)号：US20120296177A1
公开(公告)日：2012-11-22
申请号：US13564332
申请日：2012-08-01
申请人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
发明人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
IPC分类号： A61B5/0205 , A61B5/021 , A61B5/01 , A61B5/00
CPC分类号： A61N1/37252 , A61B5/0031 , A61M5/14276 , A61M5/1723 , A61M2205/3523 , A61M2205/52 , A61M2230/30 , A61N1/37217 , A61N1/37223 , G06F19/00
摘要： One embodiment of the present invention relates to a system for deriving physiologic measurement values that are relative to ambient conditions. In one embodiment, the system comprises an implantable medical device (“IMD”), an external computing device, and a backend computing system. The IMD determines a physiologic parameter value within a patient's body, and communicates the physiologic parameter value outside the patient's body, for example, to the external computing device. Further, the external computing device receives the physiologic parameter from the IMD and communicates it to the backend computing system. The backend computing system receives the physiologic parameter value and obtains an ambient condition value outside the body. The backend computing system then calculates a relative physiologic parameter value from the ambient condition value and the physiologic parameter value, and in some embodiments, stores the relative physiologic parameter value in a storage location, such as a memory or database.
摘要翻译： 本发明的一个实施例涉及用于导出相对于环境条件的生理测量值的系统。 在一个实施例中，该系统包括可植入医疗装置（IMD），外部计算装置和后端计算系统。 IMD确定患者体内的生理参数值，并将例如患者体外的生理参数值传达到外部计算设备。 此外，外部计算设备从IMD接收生理参数并将其传送到后端计算系统。 后端计算系统接收生理参数值，并获得身体外的环境条件值。 后端计算系统然后根据环境条件值和生理参数值计算相对生理参数值，并且在一些实施例中，将相对生理参数值存储在诸如存储器或数据库的存储位置中。
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12.发明授权Systems and methods for deriving relative physiologic measurements using a backend computing system 有权使用后端计算系统导出相对生理测量的系统和方法公开(公告)号：US08271093B2
公开(公告)日：2012-09-18
申请号：US10943627
申请日：2004-09-17
申请人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
发明人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
IPC分类号： A61N1/08
CPC分类号： A61N1/37252 , A61B5/0031 , A61M5/14276 , A61M5/1723 , A61M2205/3523 , A61M2205/52 , A61M2230/30 , A61N1/37217 , A61N1/37223 , G06F19/00
摘要： One embodiment of the present invention relates to a system for deriving physiologic measurement values that are relative to ambient conditions. In one embodiment, the system comprises an implantable medical device (“IMD”), an external computing device, and a backend computing system. The IMD determines an absolute physiologic parameter value within a patient's body, and communicates the absolute physiologic parameter value outside the patient's body, for example, to the external computing device. Further, the external computing device receives the absolute physiologic parameter from the IMD and communicates it to the backend computing system. The backend computing system receives the absolute physiologic parameter value and obtains an ambient condition value outside the body that can affect the absolute physiologic parameter value. The backend computing system then calculates a relative physiologic parameter value from the ambient condition value and the absolute physiologic parameter value, and in some embodiments, stores the relative physiologic parameter value in a storage location, such as a memory or database.
摘要翻译： 本发明的一个实施例涉及用于导出相对于环境条件的生理测量值的系统。 在一个实施例中，该系统包括可植入医疗装置（“IMD”），外部计算装置和后端计算系统。 IMD确定患者体内的绝对生理参数值，并将例如外部计算设备的绝对生理参数值传达到患者体外。 此外，外部计算设备从IMD接收绝对生理参数并将其传送到后端计算系统。 后端计算系统接收绝对生理参数值，并获得可能影响绝对生理参数值的身体外部的环境条件值。 后端计算系统然后根据环境条件值和绝对生理参数值计算相对生理参数值，并且在一些实施例中，将相对生理参数值存储在诸如存储器或数据库的存储位置中。
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13.发明申请Method and apparatus of acoustic communication for implantable medical device 有权用于可植入医疗器械的声学通信的方法和装置公开(公告)号：US20090143836A1
公开(公告)日：2009-06-04
申请号：US12322497
申请日：2009-02-03
申请人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
发明人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
IPC分类号： A61N1/362
CPC分类号： A61N1/37217 , A61B5/0028 , A61B5/0031 , A61N1/3727 , A61N1/37288
摘要： An implantable medical device includes an acoustic transducer for intra-body communication with another medical device via an acoustic couple. The acoustic transducer includes one or more piezoelectric transducers. In one embodiment, an implantable medical device housing contains a cardiac rhythm management (CRM) device and an acoustic communication circuit. The acoustic transducer is electrically connected to the acoustic communication circuit to function as an acoustic coupler and physically fastened to a wall of the implantable housing, directly or via a supporting structure.
摘要翻译： 可植入医疗装置包括用于通过声耦合与另一医疗装置进行体内通信的声换能器。 声换能器包括一个或多个压电换能器。 在一个实施例中，可植入医疗装置壳体包含心律管理（CRM）装置和声通信电路。 声学换能器电连接到声学通信电路，用作声学耦合器，并且直接或经由支撑结构物理地紧固到可植入壳体的壁上。
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公开(公告)号：US20080132967A1
公开(公告)日：2008-06-05
申请号：US12026220
申请日：2008-02-05
申请人： Jeffrey A. Von Arx , Abhi Chavan
发明人： Jeffrey A. Von Arx , Abhi Chavan
IPC分类号： A61N1/365
CPC分类号： A61B5/0215 , A61B5/02108 , A61B5/0422 , A61B5/0809 , A61B5/0816 , A61B5/1116 , A61B5/1118 , A61B2560/0261 , A61B2562/0219 , A61N1/36564
摘要： An implantable cardiac device is configured and programmed to collect blood pressure waveforms from one or more implantable pressure sensors. Techniques are described for extracting features and reducing noise in the pressure waveforms by averaging waveforms which are aligned with a detected cardiac cycle. Noise can also be reduced by gating and calibration functions performed in accordance with other sensor data.
摘要翻译： 可植入心脏装置被配置和编程以从一个或多个可植入压力传感器收集血压波形。 描述了通过平均与检测到的心动周期对准的波形来提取特征并降低压力波形中的噪声的技术。 通过根据其他传感器数据执行的门控和校准功能也可以降低噪声。
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公开(公告)号：US08852099B2
公开(公告)日：2014-10-07
申请号：US13564332
申请日：2012-08-01
申请人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
发明人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
CPC分类号： A61N1/37252 , A61B5/0031 , A61M5/14276 , A61M5/1723 , A61M2205/3523 , A61M2205/52 , A61M2230/30 , A61N1/37217 , A61N1/37223 , G06F19/00
摘要： One embodiment of the present invention relates to a system for deriving physiologic measurement values that are relative to ambient conditions. In one embodiment, the system comprises an implantable medical device (“IMD”), an external computing device, and a backend computing system. The IMD determines a physiologic parameter value within a patient's body, and communicates the physiologic parameter value outside the patient's body, for example, to the external computing device. Further, the external computing device receives the physiologic parameter from the IMD and communicates it to the backend computing system. The backend computing system receives the physiologic parameter value and obtains an ambient condition value outside the body. The backend computing system then calculates a relative physiologic parameter value from the ambient condition value and the physiologic parameter value, and in some embodiments, stores the relative physiologic parameter value in a storage location, such as a memory or database.
摘要翻译： 本发明的一个实施例涉及用于导出相对于环境条件的生理测量值的系统。 在一个实施例中，该系统包括可植入医疗装置（“IMD”），外部计算装置和后端计算系统。 IMD确定患者体内的生理参数值，并将例如患者体外的生理参数值传达到外部计算设备。 此外，外部计算设备从IMD接收生理参数并将其传送到后端计算系统。 后端计算系统接收生理参数值，并获得身体外的环境条件值。 后端计算系统然后根据环境条件值和生理参数值计算相对生理参数值，并且在一些实施例中，将相对生理参数值存储在诸如存储器或数据库的存储位置中。
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16.发明授权Method and apparatus of acoustic communication for implantable medical device 有权用于可植入医疗器械的声学通信的方法和装置公开(公告)号：US08165677B2
公开(公告)日：2012-04-24
申请号：US12322497
申请日：2009-02-03
申请人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
发明人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
IPC分类号： A61N1/372
CPC分类号： A61N1/37217 , A61B5/0028 , A61B5/0031 , A61N1/3727 , A61N1/37288
摘要： An implantable medical device includes an acoustic transducer for intra-body communication with another medical device via an acoustic couple. The acoustic transducer includes one or more piezoelectric transducers. In one embodiment, an implantable medical device housing contains a cardiac rhythm management (CRM) device and an acoustic communication circuit. The acoustic transducer is electrically connected to the acoustic communication circuit to function as an acoustic coupler and physically fastened to a wall of the implantable housing, directly or via a supporting structure. In one embodiment, the implantable medical device receives an incoming acoustic signal from the other medical device, detects an error rate associated with the incoming acoustic signal, and adjusts a carrier frequency for an outgoing acoustic signal to be transmitted to the other medical device using the error rate.
摘要翻译： 可植入医疗装置包括用于通过声耦合与另一医疗装置进行体内通信的声换能器。 声换能器包括一个或多个压电换能器。 在一个实施例中，可植入医疗装置壳体包含心律管理（CRM）装置和声通信电路。 声学换能器电连接到声学通信电路，用作声学耦合器，并且直接或经由支撑结构物理地紧固到可植入壳体的壁上。 在一个实施例中，可植入医疗装置接收来自另一医疗装置的输入声信号，检测与输入声信号相关联的错误率，并且调整用于使用该信号传输到另一医疗装置的输出声信号的载波频率 错误率。
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公开(公告)号：US07489967B2
公开(公告)日：2009-02-10
申请号：US10888956
申请日：2004-07-09
申请人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
发明人： Jeffrey A. Von Arx , Scott T. Mazar , Abhi Chavan
CPC分类号： A61N1/37217 , A61B5/0028 , A61B5/0031 , A61N1/3727 , A61N1/37288
摘要： An implantable medical device includes an acoustic transducer for intra-body communication with another medical device via an acoustic couple. The acoustic transducer includes one or more piezoelectric transducers. In one embodiment, an implantable medical device housing contains a cardiac rhythm management (CRM) device and an acoustic communication circuit. The acoustic transducer is electrically connected to the acoustic communication circuit to function as an acoustic coupler and physically fastened to a wall of the implantable housing, directly or via a supporting structure.
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公开(公告)号：US07335161B2
公开(公告)日：2008-02-26
申请号：US10922816
申请日：2004-08-20
申请人： Jeffrey A. Von Arx , Abhi Chavan
发明人： Jeffrey A. Von Arx , Abhi Chavan
IPC分类号： A61B5/00
CPC分类号： A61B5/0215 , A61B5/02108 , A61B5/0422 , A61B5/0809 , A61B5/0816 , A61B5/1116 , A61B5/1118 , A61B2560/0261 , A61B2562/0219 , A61N1/36564
摘要： An implantable cardiac device is configured and programmed to collect blood pressure waveforms from one or more implantable pressure sensors. Techniques are described for extracting features and reducing noise in the pressure waveforms by averaging waveforms which are aligned with a detected cardiac cycle. Noise can also be reduced by gating and calibration functions performed in accordance with other sensor data.
摘要翻译： 可植入心脏装置被配置和编程以从一个或多个可植入压力传感器收集血压波形。 描述了通过平均与检测到的心动周期对准的波形来提取特征并降低压力波形中的噪声的技术。 通过根据其他传感器数据执行的门控和校准功能也可以降低噪声。
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19.发明授权Implantable apparatus for detection of external noise using motion sensor signal 有权用于使用运动传感器信号检测外部噪声的可植入装置公开(公告)号：US08849425B2
公开(公告)日：2014-09-30
申请号：US13455136
申请日：2012-04-25
CPC分类号： A61N1/0504 , A61B5/02405 , A61B5/0452 , A61B5/11 , A61B5/686 , A61B5/6867 , A61B5/721 , A61B2562/0219
摘要： Detects external noise using a motion sensor signal for example to increase the specificity of arrhythmia detections based on active muscle noise detection. Whenever a motion signal is present that is below or above a certain frequency, for example 5 Hz, or within a certain frequency range, for example 1 to 10 Hz, and/or above a certain amplitude, for example greater than 1 mg, or close to a known motion pattern, then the detection of fast ventricular arrhythmia is suspended. For the detection of slow arrhythmia, for example asystole or syncope, an episode is confirmed when a short lasting motion sensor signal occurs. Uses a motion sensor based signal, for example as obtained from an accelerometer on an implantable electrode lead and/or implantable device.
摘要翻译： 使用运动传感器信号检测外部噪声，例如以增加基于主动肌肉噪声检测的心律失常检测的特异性。 每当存在低于或高于某一频率（例如5Hz）或在一定频率范围内（例如1至10Hz）和/或高于某一幅度（例如大于1mg）的运动信号时，或 接近已知的运动模式，然后暂停检测快速心室心律失常。 为了检测慢性心律不齐，例如心搏停止或晕厥，当发生短暂的持续运动传感器信号时，确认发作。 使用基于运动传感器的信号，例如从可植入电极引线和/或可植入装置上的加速度计获得。
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公开(公告)号：US08755899B2
公开(公告)日：2014-06-17
申请号：US12359739
申请日：2009-01-26
CPC分类号： A61N1/37229 , A61N1/37223 , A61N1/3727
摘要： An apparatus and method for enabling far-field radio-frequency communications with an implantable medical device in which an antenna is embedded within a dielectric compartment of the device. A helical antenna may be employed to save space while still permitting far-field telemetry over a desired range of frequencies.
摘要翻译： 一种用于实现与可植入医疗设备的远场射频通信的装置和方法，其中天线嵌入设备的电介质隔室内。 可以使用螺旋天线来节省空间，同时仍然允许在期望的频率范围上进行远场遥测。
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