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    Apparatus and method for treating occluded vasculature
    11.
    发明申请
    Apparatus and method for treating occluded vasculature 有权
    用于治疗闭塞性脉管系统的装置和方法

    公开(公告)号：US20050288695A1

    公开(公告)日：2005-12-29

    申请号：US10877340

    申请日：2004-06-24

    申请人： Mark Jenson ,  William Drasler ,  Daniel Lafontaine

    发明人： Mark Jenson ,  William Drasler ,  Daniel Lafontaine

    IPC分类号： A61B17/00 ,  A61B17/22

    CPC分类号： A61B17/3207 ,  A61B2017/00398 ,  A61B2017/22044 ,  A61B2017/22077

    摘要： Occluded vasculature such as occluded arterial vasculature can be recanalized using a device that is configured to penetrate an occlusion, while limiting a distance that said penetration structure can extend in order to limit inadvertent vascular damage. The device can include an elongate sheath and a stylet disposed within the elongate sheath. The elongate sheath and the stylet can include, in combination, an engagement section that is configured to limit relative axial movement between the elongate sheath and the stylet.

    摘要翻译： 封闭的脉管系统如闭塞的动脉脉管系统可以使用被配置为穿透闭塞的装置再次通气，同时限制所述穿透结构可以延伸的距离，以限制无意的血管损伤。 该装置可以包括细长护套和设置在细长护套内的探针。 细长护套和探针可以组合地包括被配置为限制细长护套和探针之间的相对轴向运动的接合部分。

    Valvuloplasty Catheter And Methods
    14.
    发明申请
    Valvuloplasty Catheter And Methods 有权
    瓣膜成形术导管及方法

    公开(公告)号：US20100094209A1

    公开(公告)日：2010-04-15

    申请号：US12576970

    申请日：2009-10-09

    申请人： William Drasler ,  Wes Pedersen ,  Mark Ungs

    发明人： William Drasler ,  Wes Pedersen ,  Mark Ungs

    IPC分类号： A61M31/00 ,  A61B5/00

    CPC分类号： A61M25/1002 ,  A61B17/22012 ,  A61B2017/22098 ,  A61M25/1011 ,  A61M25/10186 ,  A61M25/10188 ,  A61M25/1029 ,  A61M29/02 ,  A61M2025/0002 ,  A61M2025/1031 ,  A61M2025/1047 ,  A61M2025/1059 ,  A61M2025/1075 ,  A61M2025/1086 ,  A61M2025/1088

    摘要： A valvuloplasty catheter has a dog-bone shaped balloon with semi-compliant smaller diameter waist and non-compliant larger diameter bulbous end regions. The balloon centers across the valve with the waist adjacent to the annulus. One bulbous region serves to hyperextend the valve leaflets and the other assists in stabilizing the balloon position to reduce migration. The semi-compliant waist increases in diameter as fluid enters the balloon until it comes into contact with the valve annulus. The pressure within the balloon per unit of volume delivery has a greater slope after contact with the annulus than before resulting in a change in slope for the pressure versus volume curve. The diameter of the balloon and annulus are determined at this inflection point when the balloon contacts the annulus.

    摘要翻译： 瓣膜成形术导管具有具有半顺应性较小直径的腰部和非顺应性较大直径球形末端区域的狗骨形气囊。 气囊穿过瓣膜，腰围与环带相邻。 一个球茎区域用于过度扩张瓣叶，另一个有助于稳定气囊位置以减少迁移。 随着流体进入气囊直到与阀环接触，半顺应性腰部直径增加。 每单位体积输送中气囊内的压力与空气接触之后具有比之前更大的斜率，导致压力与体积曲线的斜率变化。 当球囊接触环形空间时，在该拐点处确定球囊和环的直径。

    Leadless Cardiac Stimulation Systems
    16.
    发明申请
    Leadless Cardiac Stimulation Systems 有权
    无引导心脏刺激系统

    公开(公告)号：US20070150037A1

    公开(公告)日：2007-06-28

    申请号：US11683577

    申请日：2007-03-08

    申请人： Roger Hastings ,  William Drasler ,  Daniel Lafontaine ,  Anupama Sadasiva ,  Scott Smith

    发明人： Roger Hastings ,  William Drasler ,  Daniel Lafontaine ,  Anupama Sadasiva ,  Scott Smith

    IPC分类号： A61N1/05

    CPC分类号： A61N1/3756 ,  A61N1/0587 ,  A61N1/059 ,  A61N1/08 ,  A61N1/3627 ,  A61N1/365 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37223 ,  A61N1/37229 ,  A61N1/37241 ,  A61N1/37288 ,  A61N1/375 ,  A61N1/3787

    摘要： Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.

    摘要翻译： 提供了使用无引线电极来提供起搏治疗的各种构造的系统。 在一个示例中，提供用于心脏心肌的多个部位的系统包括使用经皮，经腔，导管递送系统可植入位于心肌附近的位置的无线起搏电极。 每个电极包含用于起搏心肌的电能源，并且适于从心肌外部的源接收电磁能。 该系统还包括适于放置在心肌外部的源，并且使用局部测量的心电图来通过向电极发送电磁命令来同步心脏的起搏，以对电极周围的心肌进行加速。 还公开了用于递送和植入电极组件的这种系统，无线电极组件和输送导管的各种配置。

    CONTROL OF ARTERIAL SMOOTH MUSCLE TONE
    18.
    发明申请
    CONTROL OF ARTERIAL SMOOTH MUSCLE TONE 有权
    手术平滑肌肉调理的控制

    公开(公告)号：US20070260281A1

    公开(公告)日：2007-11-08

    申请号：US11381238

    申请日：2006-05-02

    申请人： Roger Hastings ,  William Drasler ,  Vitaly Shapovalov ,  Mark Schroeder

    发明人： Roger Hastings ,  William Drasler ,  Vitaly Shapovalov ,  Mark Schroeder

    IPC分类号： A61N1/00

    CPC分类号： A61B18/00 ,  A61N1/05 ,  A61N1/36007 ,  A61N1/36017 ,  A61N1/36117

    摘要： An apparatus for locally controlling smooth muscle tone includes a first electrode for insertion into an artery; a barrier for preventing the first electrode from contacting an arterial wall; a second electrode; a power supply; and a controller for coupling the power supply to the electrodes. The controller is configured to cause the electrode to maintain a waveform for controlling polarization of smooth muscle tone.

    摘要翻译： 用于局部控制平滑肌张力的装置包括用于插入动脉的第一电极; 用于防止第一电极接触动脉壁的屏障; 第二电极; 电源; 以及用于将电源耦合到电极的控制器。 控制器被配置为使电极保持用于控制平滑肌张力偏振的波形。

    Valvuloplasty catheter and methods
    19.
    发明授权
    Valvuloplasty catheter and methods 有权
    瓣膜成形术导管及方法

    公开(公告)号：US07951111B2

    公开(公告)日：2011-05-31

    申请号：US12576970

    申请日：2009-10-09

    申请人： William Drasler ,  Wes Pedersen ,  Mark Ungs

    发明人： William Drasler ,  Wes Pedersen ,  Mark Ungs

    IPC分类号： A61M31/00 ,  A61M37/00 ,  A61M29/00

    CPC分类号： A61M25/1002 ,  A61B17/22012 ,  A61B2017/22098 ,  A61M25/1011 ,  A61M25/10186 ,  A61M25/10188 ,  A61M25/1029 ,  A61M29/02 ,  A61M2025/0002 ,  A61M2025/1031 ,  A61M2025/1047 ,  A61M2025/1059 ,  A61M2025/1075 ,  A61M2025/1086 ,  A61M2025/1088

    摘要： A valvuloplasty catheter has a dog-bone shaped balloon with semi-compliant smaller diameter waist and non-compliant larger diameter bulbous end regions. The balloon centers across the valve with the waist adjacent to the annulus. One bulbous region serves to hyperextend the valve leaflets and the other assists in stabilizing the balloon position to reduce migration. The semi-compliant waist increases in diameter as fluid enters the balloon until it comes into contact with the valve annulus. The pressure within the balloon per unit of volume delivery has a greater slope after contact with the annulus than before resulting in a change in slope for the pressure versus volume curve. The diameter of the balloon and annulus are determined at this inflection point when the balloon contacts the annulus.

    摘要翻译： 瓣膜成形术导管具有具有半顺应性较小直径的腰部和非顺应性较大直径球形末端区域的狗骨形气囊。 气囊穿过瓣膜，腰围与环带相邻。 一个球茎区域用于过度扩张瓣叶，另一个有助于稳定气囊位置以减少迁移。 随着流体进入气囊直到与阀环接触，半顺应性腰部直径增加。 每单位体积输送中气囊内的压力与空气接触之后具有比之前更大的斜率，导致压力与体积曲线的斜率变化。 当球囊接触环形空间时，在该拐点处确定球囊和环的直径。