公开(公告)号：US20070177259A1

公开(公告)日：2007-08-02

申请号：US11651558

申请日：2007-01-10

申请人： Susumu Honda ,  Yasuaki Natori ,  Chino Sasaoka ,  Yoshihiro Kawano ,  Hinako Kaji

发明人： Susumu Honda ,  Yasuaki Natori ,  Chino Sasaoka ,  Yoshihiro Kawano ,  Hinako Kaji

IPC分类号： G02B21/26

CPC分类号： G02B21/362

摘要： The present invention provides an examination apparatus which includes a base; a stage on which a specimen is mounted, the stage being movable relative to the base; and a movable image acquisition apparatus for acquiring an image of the specimen, the movable image acquisition apparatus being fixed on the stage.

摘要翻译： 本发明提供一种检查装置，包括：基座; 安装有试样的阶段，该台可相对于底座移动; 以及可动图像获取装置，用于获取样本的图像，所述可动图像获取装置固定在所述台上。

公开(公告)号：US20070273877A1

公开(公告)日：2007-11-29

申请号：US10594311

申请日：2005-03-29

申请人： Yoshihiro Kawano ,  Keiji Shimizu ,  Minoru Sukekawa ,  Tsuyoshi Mochizuki ,  Susumu Honda ,  Kazuhiro Hayashi

发明人： Yoshihiro Kawano ,  Keiji Shimizu ,  Minoru Sukekawa ,  Tsuyoshi Mochizuki ,  Susumu Honda ,  Kazuhiro Hayashi

IPC分类号： G01J3/30 ,  G02B21/36

CPC分类号： G01N21/6458 ,  G02B21/248

摘要： Even when the magnifying power is reduced, an image can be obtained at high resolution without significantly reducing the numerical aperture, and examination accuracy is improved. There is provided a microscope examination apparatus including a light source for emitting excitation light or illumination light to a specimen placed on a stage; an objective lens opposing the stage and capable of focusing fluorescence or reflected light from the specimen; an image-forming lens for forming an image of the specimen obtained by the objective lens; and an image-capturing unit for capturing the image of the specimen forming by the image-forming lens, wherein a plurality of the objective lenses having different magnifying powers is provided, and an objective-lens switching mechanism for switching among the objective lenses is provided, and wherein a plurality of the image-forming lenses having different magnifying powers is provided, and an image-forming-lens switching mechanism for switching among the image-forming lenses 5a and 5b is provided.

摘要翻译： 即使放大倍数减小，也能够以高分辨率获得图像，而不会显着降低数值孔径，提高了检查精度。 提供了一种显微镜检查装置，其包括用于向放置在台架上的样本发射激发光或照明光的光源; 与舞台相对并且能够聚焦来自样本的荧光或反射光的物镜; 用于形成由所述物镜获得的所述样本的图像的图像形成透镜; 以及图像捕获单元，用于捕获由图像形成透镜形成的样本的图像，其中提供具有不同放大倍率的多个物镜，并且提供用于在物镜之间切换的物镜切换机构 并且其中提供了具有不同放大倍率的多个图像形成透镜，并且提供了用于在成像透镜5a和5b之间切换的图像形成透镜切换机构。

公开(公告)号：US07589839B2

公开(公告)日：2009-09-15

申请号：US10594311

申请日：2005-03-29

申请人： Yoshihiro Kawano ,  Keiji Shimizu ,  Minoru Sukekawa ,  Tsuyoshi Mochizuki ,  Susumu Honda ,  Kazuhiro Hayashi

发明人： Yoshihiro Kawano ,  Keiji Shimizu ,  Minoru Sukekawa ,  Tsuyoshi Mochizuki ,  Susumu Honda ,  Kazuhiro Hayashi

IPC分类号： G01N21/64

CPC分类号： G01N21/6458 ,  G02B21/248

摘要： A microscope examination apparatus is provided that includes a light source for emitting excitation light or illumination light to a specimen placed on a stage; an objective lens opposing the stage and capable of focusing fluorescence or reflected light from the specimen; an image-forming lens for forming an image of the specimen obtained by the objective lens; and an image-capturing unit for capturing the image of the specimen forming by the image-forming lens, wherein a plurality of the objective lenses having different magnifying powers is provided, and an objective-lens switching mechanism for switching among the objective lenses is provided, and wherein a plurality of the image-forming lenses having different magnifying powers is provided, and an image-forming-lens switching mechanism for switching among the image-forming lenses is provided.

摘要翻译： 本发明提供一种显微镜检查装置，其包括：向放置在台架上的试样发射激发光或照明光的光源; 与舞台相对并且能够聚焦来自样本的荧光或反射光的物镜; 用于形成由所述物镜获得的所述样本的图像的图像形成透镜; 以及图像捕获单元，用于捕获由图像形成透镜形成的样本的图像，其中提供具有不同放大倍率的多个物镜，并且提供用于在物镜之间切换的物镜切换机构 并且其中提供了具有不同放大倍率的多个图像形成透镜，并且提供了用于在成像透镜之间切换的图像形成透镜切换机构。

公开(公告)号：US20070047071A1

公开(公告)日：2007-03-01

申请号：US11505336

申请日：2006-08-17

申请人： Susumu Honda ,  Yoshihiro Kawano

发明人： Susumu Honda ,  Yoshihiro Kawano

IPC分类号： G02B21/00

CPC分类号： G02B21/082 ,  G02B21/002

摘要： A microscope moving unit is provided, the microscope moving unit being capable of preventing an increase in size and a decrease in operation speed of a microscope apparatus by reducing the size of the movable parts, improving the operability of the objective lens by providing a large space around the objective lens, and allowing a specimen to be observed at various positions without affecting the specimen. The microscope moving unit includes an arm that is rotatable around an optical axis of a laser beam guided from a laser light source and that supports a microscope main body on the side closer to a tip of the arm, the microscope main body having an objective lens, and a rotatable deflecting member, which is fixed to the arm, configured to deflect the laser beam and emit the deflected laser beam towards the microscope main body at the side closer to the tip of the arm.

摘要翻译： 提供显微镜移动单元，显微镜移动单元能够通过减小可移动部件的尺寸来防止显微镜装置的尺寸增加和操作速度的降低，通过提供大的空间来提高物镜的可操作性 在物镜周围，并且允许在不影响样本的各个位置观察样本。 显微镜移动单元包括臂，其能够围绕从激光源引导的激光束的光轴旋转，并且在靠近臂的末端的一侧支撑显微镜主体，显微镜主体具有物镜 以及可旋转偏转构件，其被固定到所述臂，所述可旋转偏转构件被配置为使所述激光束偏转并且在靠近所述臂的尖端的一侧朝向所述显微镜主体发射偏转的激光束。

公开(公告)号：US07912267B2

公开(公告)日：2011-03-22

申请号：US12620268

申请日：2009-11-17

申请人： Yoshihiro Kawano ,  Mitsumori Hayashida ,  Keiji Kimura ,  Iwao Kanamori

发明人： Yoshihiro Kawano ,  Mitsumori Hayashida ,  Keiji Kimura ,  Iwao Kanamori

IPC分类号： G06K9/00

CPC分类号： G06K9/2009 ,  G02B21/34 ,  G02B21/36 ,  Y10S128/922

摘要： The present invention is a virtual-slide specimen image acquisition apparatus that captures images by dividing a specimen into a plurality of sections, having a conveying device in which a plurality of specimens can be arranged and that conveys the plurality of the arranged specimens in a first direction by a distance corresponding to the length of a side along the first direction in one of the divided sections and at first time intervals and an image capturing device that has an image capturing portion for capturing images of the specimens magnified at a predetermined magnification and that scans the specimens conveyed to a predetermined position in a second direction, by a predetermined length at second time intervals, such that the image capturing portion captures images of all of the sections that are positioned identically in the first direction and that are positioned differently in the second direction perpendicular to the first direction.

摘要翻译： 本发明是一种虚拟幻灯片样本图像获取装置，其通过将样本分割成多个部分来捕获图像，该多个部分具有其中可以布置多个样本的输送装置，并且将多个排列的样本以第一 在一个分割部分中以第一时间间隔对应于沿着第一方向的一侧的长度的方向的方向和具有用于捕获以预定倍数放大的样本的图像的图像捕获部分的图像捕获装置，以及 以第二时间间隔将传送到第二方向的预定位置的样本扫描预定长度，使得图像捕获部分捕获在第一方向上相同位置并且在第二方向上不同定位的所有部分的图像 第二方向垂直于第一方向。

公开(公告)号：US20070028918A1

公开(公告)日：2007-02-08

申请号：US11498474

申请日：2006-08-02

申请人： Kei Tsuyuki ,  Yoshihisa Tanikawa ,  Yoshihiro Kawano

发明人： Kei Tsuyuki ,  Yoshihisa Tanikawa ,  Yoshihiro Kawano

IPC分类号： A61M15/00

CPC分类号： A01K1/031 ,  A22B3/00 ,  A22B3/005 ,  A61D7/04

摘要： The present invention prevents the leakage of anesthetic gas, and enables in vivo observation of a specimen such as small laboratory animals over a long period of time. An anesthetizing chamber comprises a chamber main body for housing a specimen such as a laboratory animal; an anesthetic gas supply part for supplying anesthetic gas to the chamber main body; and an anesthetic gas recovery part for recovering the anesthetic gas that is supplied into the chamber main body from the anesthetic gas supply part; wherein a transparent window is provided to at least the chamber main body.

摘要翻译： 本发明防止了麻醉气体的泄漏，并且能够长时间地在小型实验动物体内观察样本。 麻醉室包括用于容纳诸如实验动物的样本的室主体; 用于向室主体供给麻醉气体的麻醉气体供给部; 以及麻醉气体回收部，其用于回收从所述麻醉气体供给部供给到所述室主体的麻醉气体; 其中，透明窗口至少设置在所述室主体上。

公开(公告)号：US5777783A

公开(公告)日：1998-07-07

申请号：US799865

申请日：1997-02-14

申请人： Itaru Endou ,  Yasushi Kaneko ,  Yoshihiro Kawano ,  Kazuo Kajitani

发明人： Itaru Endou ,  Yasushi Kaneko ,  Yoshihiro Kawano ,  Kazuo Kajitani

IPC分类号： G02B21/18 ,  G02B21/36 ,  G02B21/06 ,  G02B21/00

CPC分类号： G02B21/36

摘要： A microscope has an optical system in which the number of photographing optical paths can be increased. The optical system includes a light source, an illuminating optical system for radiating the illuminating light to a sample, an objective lens which is opposed to the sample, an imaging lens, which is arranged in an optical path of light passed through the objective lens, a first beam splitting block, arranged in an optical path between the objective lens and the primary image, for splitting the light passed through the imaging lens into at least three different directions, a second beam splitting block for splitting one of the light split by the first beam splitting block into a plurality of directions, an observation optical path which receives the light split by the second beam splitting block, and a plurality of photographing optical paths provided for the split light, wherein images of the same magnification are formed.

摘要翻译： 显微镜具有可以增加拍摄光路数量的光学系统。 光学系统包括光源，用于将照明光照射到样本的照明光学系统，与样本相对的物镜，配置在通过物镜的光的光路中的成像透镜， 第一分束块，布置在物镜和主图像之间的光路中，用于将通过成像透镜的光分成至少三个不同的方向;第二光束分割块，用于将光分离的光 第一分束块分成多个方向，接收由第二分束块分割的光的观察光路，以及为分裂光设置的多个摄影光路，其中形成相同倍率的图像。

公开(公告)号：US5212375A

公开(公告)日：1993-05-18

申请号：US772243

申请日：1991-10-07

申请人： Hisashi Goto ,  Tsutomu Uzawa ,  Yoshihiro Kawano ,  Hiroyuki Kurita ,  Hideaki Yoshida ,  Akira Hasegawa ,  Kimihiko Nishioka

发明人： Hisashi Goto ,  Tsutomu Uzawa ,  Yoshihiro Kawano ,  Hiroyuki Kurita ,  Hideaki Yoshida ,  Akira Hasegawa ,  Kimihiko Nishioka

IPC分类号： G02B5/32 ,  G02B7/28 ,  G03B7/099

CPC分类号： G02B5/32 ,  G02B7/28 ,  G03B7/09972 ,  G03B7/09976

摘要： An imaging system having a focus detecting device performs focus detection by detecting an output signal indicative of intensity distribution of light derived from a light-receiving element, in which at least one holographic optical element is arranged on the object side of a primary imaging plane to form an image on the light-receiving element. Thus, the imaging system has significant advantages in practical use that the arrangement is simple and the camera body is made compact.

摘要翻译： 具有焦点检测装置的成像系统通过检测指示从光接收元件导出的光的强度分布的输出信号来执行焦点检测，其中至少一个全息光学元件被布置在主成像平面的物体侧， 在光接收元件上形成图像。 因此，成像系统在实际应用中具有显着的优点，即布置简单，并且相机体紧凑。

公开(公告)号：US20100128962A1

公开(公告)日：2010-05-27

申请号：US12620268

申请日：2009-11-17

申请人： Yoshihiro Kawano ,  Mitsumori Hayashida ,  Keiji Kimura ,  Iwao Kanamori

发明人： Yoshihiro Kawano ,  Mitsumori Hayashida ,  Keiji Kimura ,  Iwao Kanamori

IPC分类号： G06K9/00

CPC分类号： G06K9/2009 ,  G02B21/34 ,  G02B21/36 ,  Y10S128/922

摘要： The present invention is a virtual-slide specimen image acquisition apparatus that captures images by dividing a specimen into a plurality of sections, having a conveying device in which a plurality of specimens can be arranged and that conveys the plurality of the arranged specimens in a first direction by a distance corresponding to the length of a side along the first direction in one of the divided sections and at first time intervals and an image capturing device that has an image capturing portion for capturing images of the specimens magnified at a predetermined magnification and that scans the specimens conveyed to a predetermined position in a second direction, by a predetermined length at second time intervals, such that the image capturing portion captures images of all of the sections that are positioned identically in the first direction and that are positioned differently in the second direction perpendicular to the first direction.

摘要翻译： 本发明是一种虚拟幻灯片样本图像获取装置，其通过将样本分割成多个部分来捕获图像，该多个部分具有其中可以布置多个样本的输送装置，并且将多个排列的样本以第一 在一个分割部分中以第一时间间隔对应于沿着第一方向的一侧的长度的方向的方向和具有用于捕获以预定倍数放大的样本的图像的图像捕获部分的图像捕获装置，以及 以第二时间间隔将传送到第二方向的预定位置的样本扫描预定长度，使得图像捕获部分捕获在第一方向上相同位置并且在第二方向上不同定位的所有部分的图像 第二方向垂直于第一方向。

公开(公告)号：US07616292B2

公开(公告)日：2009-11-10

申请号：US11648638

申请日：2007-01-03

申请人： Susumu Kikuchi ,  Yoshihiro Kawano ,  Masahiro Oba

发明人： Susumu Kikuchi ,  Yoshihiro Kawano ,  Masahiro Oba

IPC分类号： G01C11/12

CPC分类号： G01N21/6458 ,  A61B5/14556 ,  G01N21/6428 ,  G01N21/6486 ,  G01N2021/1787 ,  G02B21/365

摘要： The invention provides an examination apparatus including an objective optical system for positioning a focal point inside a specimen mounted on a stage; an image-acquisition apparatus for detecting light emitted in different optical-axis directions from the vicinity of the focal point inside the specimen and collected by the objective optical system to acquire a plurality of pieces of image information; and a three-dimensional image forming unit for forming a three-dimensional image of a light-emitting site in the vicinity of the focal point based on the plurality of pieces of image information acquired by the image-acquiring apparatus.

摘要翻译： 本发明提供了一种检查装置，其包括用于将焦点定位在安装在台架上的样本内的物镜光学系统; 用于从所述物体光学系统收集的，从所述样本内的所述焦点附近检测在不同的光轴方向上发出的光的摄像装置，以获取多张图像信息; 以及三维图像形成单元，用于基于由图像获取装置获取的多条图像信息，在焦点附近形成发光位置的三维图像。