4-thio coumarins
    12.
    发明授权
    4-thio coumarins 失效
    4-硫香豆素

    公开(公告)号:US07148253B2

    公开(公告)日:2006-12-12

    申请号:US10752654

    申请日:2004-01-06

    IPC分类号: A61K31/35

    CPC分类号: C07D311/56 C07D311/54

    摘要: 4-Thio substituted coumarin derivatives, 4,5-dithio substituted coumarin derivatives, and coumarin dimers are provided, as well as processes for their preparation. The invention also provides a method and composition for the treatment of hepatitis C virus (HCV) by adiministering 4-thio substituted coumarin derivatives, 4,5-dithio substituted coumarin derivatives, and coumarin dimers.

    摘要翻译: 提供4-硫代取代的香豆素衍生物,4,5-二硫代取代的香豆素衍生物和香豆素二聚体,以及其制备方法。 本发明还提供了通过加入4-硫代取代的香豆素衍生物,4,5-二硫基取代的香豆素衍生物和香豆素二聚体来治疗丙型肝炎病毒(HCV)的方法和组合物。

    4-thio coumarins
    13.
    发明授权
    4-thio coumarins 失效
    4-硫香豆素

    公开(公告)号:US06703514B2

    公开(公告)日:2004-03-09

    申请号:US10437768

    申请日:2003-05-13

    IPC分类号: C07D31102

    CPC分类号: C07D311/56

    摘要: 4-thio substituted coumarin derivatives and coumarin dimers are provided, as well as processes for their preparation. A synthetic process for the preparation of 4-thio substituted coumarin derivatives is provided using mild reaction conditions, which maintains a high substituent tolerance and is appropriate for use in solid phase syntheses for producing a library of 4-thio substituted coumarin derivatives for biological screening.

    摘要翻译: 提供4-硫代取代的香豆素衍生物和香豆素二聚体,以及它们的制备方法。 提供了用于制备4-硫代取代香豆素衍生物的合成方法,其使用温和的反应条件,其保持高的取代基耐受性,并且适用于制备用于生物筛选的4-硫代取代的香豆素衍生物文库的固相合成。

    PROTECTED ELECTRONIC COMMUNICATION
    15.
    发明申请

    公开(公告)号:US20190394347A1

    公开(公告)日:2019-12-26

    申请号:US16481359

    申请日:2017-02-15

    IPC分类号: H04N1/00 H04N1/32

    摘要: Examples disclosed herein relate to a protected electronic communication method comprising assigning a protected electronic communication to a data element, wherein the protected electronic communication comprises a plurality of identifier segments, receiving a request for the data element to be included in an analytics report, determining, according to the protected electronic communication, whether the data element is permitted to be included in the analytics report, and in response to determining that the data element is permitted to be included in the analytics report, providing the data element for use in the analytics report.

    Method and apparatus of generating update parameters and displaying correlated keywords

    公开(公告)号:US08676811B2

    公开(公告)日:2014-03-18

    申请号:US12594930

    申请日:2007-08-28

    IPC分类号: G06F17/30

    摘要: Provided is a method of generating updating parameters. The method obtains search keywords used by users within a predetermined time period; counts the search keywords to obtain primary keywords, related keywords, co-search frequencies of each primary keyword and the respective related keywords being searched together, and search frequencies of the primary keywords being searched alone; computes first feature values based on the search frequencies of the primary keywords being searched alone; and then computes second feature values based on the first feature values and the co-search frequencies of the primary keywords and the respective related keywords. The second feature values serve as updating parameters for determining displaying modes of the related keywords. An apparatus of generating updating parameters, and a method and an apparatus of displaying related keywords according to the updating parameters are also provided. The solution keeps abreast with the user trends to allow a better user experience and improve computing performance and efficiency. For a service provider, no special secret algorithm is needed, and the operation is easy with a low development cost.

    Data access method and configuration management database system
    17.
    发明授权
    Data access method and configuration management database system 失效
    数据访问方法和配置管理数据库系统

    公开(公告)号:US08639720B2

    公开(公告)日:2014-01-28

    申请号:US12970485

    申请日:2010-12-16

    IPC分类号: G06F17/30 G06F7/00

    CPC分类号: G06F17/30

    摘要: A computer implemented method for accessing data begins with receipt of a data access request. In response to determining that the requested data needs to be acquired in real time from an original data source, the processor acquires and stores that data. In response to determining that the data cannot be acquired in real time from the data source, the processor acquires the data from a configuration management database in which the requested data was previously stored.

    摘要翻译: 用于访问数据的计算机实现的方法从接收到数据访问请求开始。 响应于确定需要从原始数据源实时获取所请求的数据,处理器获取并存储该数据。 响应于确定不能从数据源实时获取数据,处理器从配置管理数据库中获取先前存储了请求的数据的数据。

    Cyclohexylamines, phenylamines and uses thereof
    18.
    发明授权
    Cyclohexylamines, phenylamines and uses thereof 失效
    环己胺,苯胺及其用途

    公开(公告)号:US08242142B2

    公开(公告)日:2012-08-14

    申请号:US12543480

    申请日:2009-08-18

    申请人: Shuo Lin Zhen Yang

    发明人: Shuo Lin Zhen Yang

    IPC分类号: A61K31/4406 C07D409/12

    CPC分类号: C07D409/04

    摘要: Compounds having the formula I, their methods of synthesis, and pharmaceutically acceptable salts of certain of them are provided in which the variables have the definitions described herein. Compositions including the compounds having the formula I-A in which the variables have the definitions described herein, and methods of using the compositions for the treatment of certain diseases mediated by the up-regulation of Smo are also disclosed.

    摘要翻译: 提供了具有式I的化合物,其合成方法及其某些药学上可接受的盐,其中变量具有本文所述的定义。 还公开了包括具有式I-A的化合物的组合物,其中变量具有本文所述的定义,以及使用该组合物治疗由上调Smo介导的某些疾病的方法。

    Electrically programmable device with embedded EEPROM and method for making thereof
    19.
    发明授权
    Electrically programmable device with embedded EEPROM and method for making thereof 有权
    具有嵌入式EEPROM的电子可编程器件及其制造方法

    公开(公告)号:US07759194B2

    公开(公告)日:2010-07-20

    申请号:US12180389

    申请日:2008-07-25

    IPC分类号: H01L27/115

    摘要: An electrically programmable device with embedded EEPROM and method for making thereof. The method includes providing a substrate including a first device region and a second device region, growing a first gate oxide layer in the first device region and the second device region, and forming a first diffusion region in the first device region and a second diffusion region and a third diffusion region in the second device region. Additionally, the method includes implanting a first plurality of ions to form a fourth diffusion region in the first device region and a fifth diffusion region in the second device region. The fourth diffusion region overlaps with the first diffusion region.

    摘要翻译: 具有嵌入式EEPROM的电可编程器件及其制造方法。 该方法包括提供包括第一器件区域和第二器件区域的衬底,在第一器件区域和第二器件区域中生长第一栅极氧化物层,以及在第一器件区域中形成第一扩散区域和第二扩散区域 以及第二装置区域中的第三扩散区域。 此外,该方法包括:注入第一多个离子以在第一器件区域中形成第四扩散区域,并在第二器件区域中形成第五扩散区域。 第四扩散区域与第一扩散区域重叠。

    ELECTRICALLY PROGRAMMABLE DEVICE WITH EMBEDDED EEPROM AND METHOD FOR MAKING THEREOF
    20.
    发明申请
    ELECTRICALLY PROGRAMMABLE DEVICE WITH EMBEDDED EEPROM AND METHOD FOR MAKING THEREOF 有权
    具有嵌入式EEPROM的电可编程器件及其制造方法

    公开(公告)号:US20100019308A1

    公开(公告)日:2010-01-28

    申请号:US12180389

    申请日:2008-07-25

    IPC分类号: H01L27/115 H01L21/8247

    摘要: An electrically programmable device with embedded EEPROM and method for making thereof. The method includes providing a substrate including a first device region and a second device region, growing a first gate oxide layer in the first device region and the second device region, and forming a first diffusion region in the first device region and a second diffusion region and a third diffusion region in the second device region. Additionally, the method includes implanting a first plurality of ions to form a fourth diffusion region in the first device region and a fifth diffusion region in the second device region. The fourth diffusion region overlaps with the first diffusion region.

    摘要翻译: 具有嵌入式EEPROM的电可编程器件及其制造方法。 该方法包括提供包括第一器件区域和第二器件区域的衬底,在第一器件区域和第二器件区域中生长第一栅极氧化物层,以及在第一器件区域中形成第一扩散区域和第二扩散区域 以及第二装置区域中的第三扩散区域。 此外,该方法包括:注入第一多个离子以在第一器件区域中形成第四扩散区域,并在第二器件区域中形成第五扩散区域。 第四扩散区域与第一扩散区域重叠。