Method for the manufacture of Efavirenz

    公开(公告)号:US10689353B2

    公开(公告)日:2020-06-23

    申请号:US16488975

    申请日:2018-02-15

    IPC分类号: C07D263/58

    摘要: This invention relates to a method for the manufacture of optically pure (S)-6-chloro-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Specifically, this invention relates to a flow synthesis method for the manufacture of (S)-6-chloro-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one.

    Processing carbonaceous materials
    12.
    发明授权

    公开(公告)号:US10465121B2

    公开(公告)日:2019-11-05

    申请号:US15038301

    申请日:2014-11-19

    发明人: Bernard Zeelie

    摘要: A method of processing a carbonaceous material in the form of carbonaceous fines is provided in which the carbonaceous material is treated with micro-algae to adsorb the micro-algae onto the carbonaceous material followed by heating in a heat activating step. Such heating is effected to a temperature within the range of from that at which water starts evaporating to a temperature at which volatile components of the carbonaceous material start to volatilize. The heating is continued for a duration selected to allow chemical interaction between the micro-algae and the carbonaceous material so as to alter the chemical structure of the carbonaceous material. The carbonaceous material microalgae are preferably in the form of substantially intact cells that are still in a photosynthetically active state. Dry carbonaceous materials may be mixed with micro-algae slurry in water, or micro-algae may be added to carbonaceous material already present in water.

    Processing Carbonaceous Materials
    14.
    发明申请
    Processing Carbonaceous Materials 审中-公开
    加工碳质材料

    公开(公告)号:US20160289567A1

    公开(公告)日:2016-10-06

    申请号:US15038301

    申请日:2014-11-19

    发明人: Bernard Zeelie

    IPC分类号: C10B53/02 C10B57/08 C10B53/04

    摘要: A method of processing a carbonaceous material in the form of carbonaceous fines is provided in which the carbonaceous material is treated with micro-algae to adsorb the micro-algae onto the carbonaceous material followed by heating in a heat activating step. Such heating is effected to a temperature within the range of from that at which water starts evaporating to a temperature at which volatile components of the carbonaceous material start to volatilize. The heating is continued for a duration selected to allow chemical interaction between the micro-algae and the carbonaceous material so as to alter the chemical structure of the carbonaceous material. The carbonaceous material microalgae are preferably in the form of substantially intact cells that are still in a photosynthetically active state. Dry carbonaceous materials may be mixed with micro-algae slurry in water, or micro-algae may be added to carbonaceous material already present in water.

    摘要翻译: 提供了一种处理碳质细屑形式的碳质材料的方法,其中碳质材料用微藻处理以将微藻吸附到碳质材料上,然后在热激活步骤中加热。 这样的加热进行到从水开始蒸发的温度到含碳材料的挥发性成分开始挥发的温度的范围内的温度。 加热持续一段时间以选择以允许微藻和碳质材料之间的化学相互作用,以便改变碳质材料的化学结构。 碳质材料微藻优选为仍处于光合作用状态的基本上完整的细胞的形式。 干燥的碳质材料可以与水中的微藻浆料混合,或者可以将微藻添加到已经存在于水中的碳质材料中。

    Carbonaceous Fines Beneficiation Using Micro-Algae and Related Processes
    15.
    发明申请
    Carbonaceous Fines Beneficiation Using Micro-Algae and Related Processes 审中-公开
    使用微藻和相关过程的碳质细粉受益

    公开(公告)号:US20160002553A1

    公开(公告)日:2016-01-07

    申请号:US14853505

    申请日:2015-09-14

    摘要: A method is provided for the treatment of water containing micro-algae wherein the water is contacted with carbonaceous fines to adsorb micro-algae onto particles of the carbonaceous fines. The carbonaceous fines may be coal or charcoal fines or mixtures thereof. The carbonaceous fines may be pre-treated to remove any unsuitable or valuable materials therefrom; or to produce suitable size ranges of particles for one or more purposes selected from facilitating adsorption; handling of the carbonaceous fines both before and after adsorption of the micro-algae; and separation of the carbonaceous fines with adsorbed micro-algae thereon. The method may target the beneficiation of carbonaceous fines and the carbonaceous fines together with the adsorbed microalgae thereon may be subjected to an agglomeration process for the production of agglomerates such as briquettes or pellets. The method may target the upgrading of a polluted water system in a commercial water treatment process.

    摘要翻译: 提供了一种处理含水微藻的方法,其中水与碳质细粉接触以将微藻吸附到含碳细粉粒上。 碳质细粉可以是煤或炭粉或其混合物。 碳质细粉可以进行预处理以从其中除去任何不合适或有价值的材料; 或为了一个或多个目的产生合适尺寸范围的颗粒,其选自促进吸附; 处理微藻吸附前后的碳质细粉; 并将碳质细粉与其上吸附的微藻分离。 该方法可以针对碳质细粉的选矿,并且碳质细粒与其上吸附的微藻一起可以进行聚集过程,用于生产团块例如团块或丸粒。 该方法可以针对商业水处理过程中污水系统的升级。

    Method and circuit structure for suppressing single event transients or glitches in digital electronic circuits
    16.
    发明授权
    Method and circuit structure for suppressing single event transients or glitches in digital electronic circuits 有权
    用于抑制数字电子电路中的单事件瞬变或毛刺的方法和电路结构

    公开(公告)号:US08975913B2

    公开(公告)日:2015-03-10

    申请号:US14353215

    申请日:2012-10-19

    发明人: Farouk Smith

    摘要: A circuit structure (200) for suppressing single event transients (SETs) or glitches in digital electronic circuits is provided. The circuit structure includes a first input (100) which receives an output of a digital electronic circuit (A), a second input (100′) which receives a redundant or duplicated output of the digital electronic circuit (A′), and two sub-circuits (102, 106) that each receive the inputs and have one output. One of the sub-circuits is insensitive to a change in the value of one of its inputs when the inputs are in a first logic state and the other sub-circuit is insensitive to a change in the value of one of the inputs when the inputs are in a second, inverted logic state. The sub-circuit outputs are input into a two-input multiplexer (202) which has its output (204) connected to its selection port (SEL), and the sub-circuits are arranged so that the sub-circuit which is insensitive to a change in the value of one of its inputs is selected whenever the output of the multiplexer changes. The multiplexer output (204) is provided as a final output in which SETs and glitches have been suppressed.

    摘要翻译: 提供了用于抑制数字电子电路中的单事件瞬变(SET)或毛刺的电路结构(200)。 电路结构包括接收数字电子电路(A)的输出的第一输入(100),接收数字电子电路(A')的冗余或复制输出的第二输入(100')和两个子 - 电路(102,106),每个接收输入并具有一个输出。 当输入处于第一逻辑状态时,其中一个子电路对其输入之一的值的变化不敏感,另一个子电路对输入之一的值的变化不敏感时 处于第二个反转逻辑状态。 子电路输出被输入到其输出(204)连接到其选择端口(SEL)的双输入多路复用器(202)中,并且子电路被布置成使得不对A的电路不敏感的子电路 每当多路复用器的输出变化时,选择其输入之一的值的变化。 复用器输出(204)被提供为其中已经抑制了集合和毛刺的最终输出。

    CARBONACEOUS FINES BENEFICIATION USING MICRO-ALGAE AND RELATED PROCESSES
    17.
    发明申请
    CARBONACEOUS FINES BENEFICIATION USING MICRO-ALGAE AND RELATED PROCESSES 审中-公开
    使用微藻和相关方法的碳水化合物的益处

    公开(公告)号:US20130199087A1

    公开(公告)日:2013-08-08

    申请号:US13818287

    申请日:2011-08-16

    IPC分类号: C10L5/44 C02F1/28

    摘要: A method is provided for the treatment of water containing micro-algae wherein the water is contacted with carbonaceous fines to adsorb micro-algae onto particles of the carbonaceous fines. The carbonaceous fines may be coal or charcoal fines or mixtures thereof. The carbonaceous fines may be pre-treated to remove any unsuitable or valuable materials therefrom; or to produce suitable size ranges of particles for one or more purposes selected from facilitating adsorption; handling of the carbonaceous fines both before and after adsorption of the micro-algae; and separation of the carbonaceous fines with adsorbed micro-algae thereon. The method may target the beneficiation of carbonaceous fines and the carbonaceous fines together with the adsorbed microalgae thereon may be subjected to an agglomeration process for the production of agglomerates such as briquettes or pellets. The method may target the upgrading of a polluted water system in a commercial water treatment process.

    摘要翻译: 提供了一种处理含水微藻的方法,其中水与碳质细粉接触以将微藻吸附到含碳细粉粒上。 碳质细粉可以是煤或炭粉或其混合物。 碳质细粉可以进行预处理以从其中除去任何不合适或有价值的材料; 或为了一个或多个目的产生合适尺寸范围的颗粒,其选自促进吸附; 处理微藻吸附前后的碳质细粉; 并将碳质细粉与其上吸附的微藻分离。 该方法可以针对碳质细粉的选矿,并且碳质细粒与其上吸附的微藻一起可以进行聚集过程,用于生产团块例如团块或丸粒。 该方法可以针对商业水处理过程中污水系统的升级。