公开(公告)号：US20170160366A1

公开(公告)日：2017-06-08

申请号：US15301868

申请日：2015-04-16

申请人： THE GENERAL HOSPITAL CORPORATION

发明人： Matthew D. Tisdale ,  Andrew J.W. Van Der Kouwe

IPC分类号： G01R33/565 ,  A61B5/055

CPC分类号： G01R33/56509 ,  A61B5/055 ,  G01R33/483 ,  G01R33/5613 ,  G01R33/5616 ,  G01R33/5673

摘要： A system and method for reconstructing an image of a subject, in which motion has been prospectively corrected, using a magnetic resonance imaging (MRI] system are provided. An imaging pulse sequence is used to acquire image data in addition to navigator data using an ultra-fast navigator, such as a cloverleaf navigator. When motion is detected in the navigator data, a volume navigator (vNav] sequence is performed, from which motion estimates are generated and used to update the imaging pulse sequence to prospectively correct for the motion in subsequent repetition times.

公开(公告)号：US20170139023A1

公开(公告)日：2017-05-18

申请号：US15349294

申请日：2016-11-11

申请人： Toshiba Medical Systems Corporation

发明人： Hiroshi KUSAHARA ,  Yuki TAKAI

IPC分类号： G01R33/385 ,  G01R33/28 ,  G01R33/3873

CPC分类号： G01R33/3856 ,  G01R33/283 ,  G01R33/3873 ,  G01R33/4816 ,  G01R33/4818 ,  G01R33/482 ,  G01R33/4822 ,  G01R33/4824 ,  G01R33/4826 ,  G01R33/483 ,  G01R33/4831 ,  G01R33/546

摘要： A magnetic-resonance imaging apparatus of an embodiment includes a gradient coil, a transmitter coil, and a processing circuitry. The gradient coil applies a gradient magnetic field to an imaging space in which a subject is placed. The transmitter coil applies a RF (radio frequency) pulse to the imaging space. The processing circuitry calculates a target temperature of the gradient coil throughout multiple protocols to be executed in an examination of the subject, and controls a temperature of the gradient coil to approach the target temperature when a data used to set a center frequency of the RF pulse is measured.

公开(公告)号：US09651639B2

公开(公告)日：2017-05-16

申请号：US13894623

申请日：2013-05-15

申请人： Björn Heismann ,  Arne Hengerer ,  Sebastian Schmidt

发明人： Björn Heismann ,  Arne Hengerer ,  Sebastian Schmidt

IPC分类号： G01R33/48 ,  G01R33/483 ,  A61B5/055 ,  G01R33/485 ,  G01R33/563

CPC分类号： G01R33/485 ,  A61B5/055 ,  G01R33/48 ,  G01R33/4806 ,  G01R33/483 ,  G01R33/5616 ,  G01R33/56366

摘要： A method for determining a change over time in a biomarker in a region to be examined of a patient is provided. The change is determined from magnetic resonance data using a magnetic resonance measuring system with sequences and protocols for measuring the biomarkers by functional resting state connectivity by rsfMRI, perfusion values, magnetic resonance spectra of voxels, or morphometry of organs. A control unit has programs which evaluates the biomarker and a data memory which stores the results of the evaluation and additional data. During a first examination, a quantity result of the biomarkers is determined and stored in the data memory. During a follow-up examination, at least one previous item of the result and additional data from the first examination stored in the data memory are used for determining a quantitative change in the biomarker.

公开(公告)号：US20160054408A1

公开(公告)日：2016-02-25

申请号：US14832120

申请日：2015-08-21

申请人： Siemens Aktiengesellschaft

发明人： Wilhelm Horger ,  Michael Koehler ,  Dieter Ritter ,  Michael Wullenweber

IPC分类号： G01R33/3875 ,  G01R33/36 ,  G01R33/54

CPC分类号： G01R33/3875 ,  G01R33/36 ,  G01R33/483 ,  G01R33/543 ,  G01R33/5659 ,  G01R33/583

摘要： In a method and magnetic resonance apparatus for performing at least one adjusting measurement for the magnetic resonance apparatus, a localizing measurement is performed using the magnetic resonance apparatus and a localization dataset is created, and at least one examination region on the localization dataset. At least one examination region of the localization dataset is selected, and at least one adjusting measurement is performed according to the at least one selected examination region. The at least one adjusting measurement can be the calculation of a radio-frequency pulse amplitude, the calculation of a system frequency and the calculation of at least one current of at least one shim coil.

摘要翻译： 在用于对磁共振装置执行至少一个调整测量的方法和磁共振装置中，使用磁共振装置执行定位测量，并且创建定位数据集，以及定位数据集上的至少一个检查区域。 选择定位数据集的至少一个检查区域，并且根据至少一个所选择的检查区域执行至少一个调整测量。 所述至少一个调整测量可以是射频脉冲幅度的计算，系统频率的计算和至少一个垫片线圈的至少一个电流的计算。

公开(公告)号：US20150374258A1

公开(公告)日：2015-12-31

申请号：US14625918

申请日：2015-02-19

申请人： NOCIMED, LLC

发明人： James Clayton Peacock, III ,  John Patrick Claude ,  Paul Henry Kane ,  Ricardo Dario Pradenas

IPC分类号： A61B5/055 ,  G01R33/46 ,  G06T7/00 ,  A61B5/00

CPC分类号： A61B5/055 ,  A61B5/0075 ,  A61B5/4566 ,  A61B5/4824 ,  A61B5/7257 ,  G01R33/4625 ,  G01R33/4828 ,  G01R33/483 ,  G01R33/5608 ,  G06T7/0012 ,  Y10S128/922 ,  Y10S128/923

摘要： Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.

摘要翻译： 提供了系统和方法，用于从来自受试者的感兴趣区域（ROI）的多帧MRS采集系列处理一组多个串行获取的磁共振波谱（MRS）无感应衰减（FID）帧，并且用于提供 后处理MRS谱。 处理参数是动态变化的，同时测量结果以确定最佳后处理结果。 对来自感兴趣化学区域的水相对的光谱区域进行评估，并在至少一个处理操作中使用。 通过自由感应衰减（FID）帧和参考光谱之间的频谱相关估计频移误差。 所获取的集合内的多组FID帧被识别为与采集的相位阶跃循环相对应的不同阶段。 基线校正也通过秩序滤波（ROF）估计和多项式拟合进行。 可以从多项式拟合中排除ROF的部分，例如被确定为与相关光谱峰相关联的部分。

公开(公告)号：US20150323632A1

公开(公告)日：2015-11-12

申请号：US14705898

申请日：2015-05-06

申请人： Phillip Zhe Sun

发明人： Phillip Zhe Sun

IPC分类号： G01R33/56 ,  G01R33/48 ,  G01R33/483

CPC分类号： G01R33/4804 ,  G01R33/4828 ,  G01R33/483 ,  G01R33/5601 ,  G01R33/5605 ,  G01R33/5608

摘要： Systems and methods for indicating pH in a subject using a magnetic resonance imaging (MRI) system are provided. The method includes selecting a contrast agent, generating a chemical exchange saturation transfer (CEST) pulse sequence, performing the pulse sequence with the saturating pulse at a first power level, and performing the pulse sequence again with the saturating pulse at a power level different from the first power level. The method also includes generating values indicating pH of the subject, and generating a report indicating the pH using those values.

摘要翻译： 提供了使用磁共振成像（MRI）系统来指示受试者的pH的系统和方法。 该方法包括选择造影剂，产生化学交换饱和转移（CEST）脉冲序列，以饱和脉冲在第一功率电平下执行脉冲序列，并且以与饱和脉冲不同的功率电平再次用饱和脉冲执行脉冲序列 第一个功率级别。 该方法还包括产生指示受试者的pH的值，以及使用这些值生成指示pH的报告。

公开(公告)号：US09097777B2

公开(公告)日：2015-08-04

申请号：US13443908

申请日：2012-04-11

申请人： Hans Weber ,  Maxim Zaitsev ,  Daniel Gallichan ,  Juergen Hennig

发明人： Hans Weber ,  Maxim Zaitsev ,  Daniel Gallichan ,  Juergen Hennig

IPC分类号： G01R33/483

CPC分类号： G01R33/4833 ,  G01R33/483 ,  G01R33/4835 ,  G01R33/4836

摘要： A method of MR imaging applies a magnetic field Bgrad1 having a spatially non-linear dependence to select a volume of at least one curved slice. The slice is described by its midsurface AM, a volume of the selected slice being made up of nν partial volumes in each of which gradients of at least one pair of remaining superimposed magnetic fields Bgradi (i>1) exhibit an angle dependence of 70° to 110° with respect to one another and with respect to the normal of the midsurface AM. At least one superimposed magnetic field of the respective pair exhibits a spatially non-linear dependence and combinations of these pairs are used for spatial encoding. In this way, curved surfaces can be mapped efficiently in high resolution and the method can be adapted to the slice shape.

摘要翻译： MR成像的方法应用具有空间非线性依赖性的磁场Bgrad1来选择至少一个弯曲切片的体积。 切片由其中心面AM描述，所选切片的体积由n＆ngr组成; 至少一对剩余叠加磁场Bgradi（i> 1）的梯度中的每一个的部分体积相对于彼此表现出70°至110°的角度依赖性，并且相对于中空面AM的法线呈现角度依赖性。 相应对的至少一个叠加的磁场表现出空间非线性相关性，并且这些对的组合用于空间编码。 以这种方式，可以高分辨率地有效地映射曲面，并且该方法可以适应于切片形状。

公开(公告)号：US08951500B2

公开(公告)日：2015-02-10

申请号：US12376470

申请日：2007-08-17

申请人： Kevin M. Brindle ,  Samuel Evan Day ,  Mikko Iivari Kettunen

发明人： Kevin M. Brindle ,  Samuel Evan Day ,  Mikko Iivari Kettunen

IPC分类号： G01R33/46 ,  G01R33/483 ,  G01R33/465 ,  A61B5/055 ,  G01R33/56 ,  G01R33/48

CPC分类号： G01R33/465 ,  A61B5/055 ,  G01R33/4828 ,  G01R33/483 ,  G01R33/5601

摘要： The invention relates to method of 13C-MR imaging and/or 13C-MR spectroscopy of cell death using an imaging medium which comprises hyperpolarized 13C-pyruvate.

摘要翻译： 本发明涉及使用包含超极化13 C-丙酮酸的成像介质的13C-MR成像和/或13C-MR光谱法的细胞死亡的方法。

公开(公告)号：US20140064586A1

公开(公告)日：2014-03-06

申请号：US13843117

申请日：2013-03-15

申请人： NOCIMED, LLC

发明人： James Clayton Peacock, III ,  John Patrick Claude ,  Paul Henry Kane ,  Ricardo Dario Pradenas

IPC分类号： G01R33/46 ,  G06T7/00 ,  A61B5/055 ,  G01R33/56 ,  G01R33/48

CPC分类号： A61B5/055 ,  A61B5/0075 ,  A61B5/4566 ,  A61B5/4824 ,  A61B5/7257 ,  G01R33/4625 ,  G01R33/4828 ,  G01R33/483 ,  G01R33/5608 ,  G06T7/0012 ,  Y10S128/922 ,  Y10S128/923

摘要： Systems and methods are provided for processing a set of multiple serially acquired magnetic resonance spectroscopy (MRS) free induction decay (FID) frames from a multi-frame MRS acquisition series from a region of interest (ROI) in a subject, and for providing a post-processed MRS spectrum. Processing parameters are dynamically varied while measuring results to determine the optimal post-processed results. Spectral regions opposite water from chemical regions of interest are evaluated and used in at least one processing operation. Frequency shift error is estimated via spectral correlation between free induction decay (FID) frames and a reference spectrum. Multiple groups of FID frames within the acquired set are identified to different phases corresponding with a phase step cycle of the acquisition. Baseline correction is also performed via rank order filter (ROF) estimate and a polynomial fit. Sections of the ROF may be excluded from the polynomial fit, such as for example sections determined to be associated with relevant spectral peaks.

摘要翻译： 提供了系统和方法，用于从来自受试者的感兴趣区域（ROI）的多帧MRS采集系列处理一组多个串行获取的磁共振波谱（MRS）无感应衰减（FID）帧，并且用于提供 后处理MRS谱。 处理参数是动态变化的，同时测量结果以确定最佳后处理结果。 对来自感兴趣化学区域的水相对的光谱区域进行评估，并在至少一个处理操作中使用。 通过自由感应衰减（FID）帧和参考光谱之间的频谱相关估计频移误差。 所获取的集合内的多组FID帧被识别为与采集的相位阶跃循环相对应的不同阶段。 基线校正也通过秩序滤波（ROF）估计和多项式拟合进行。 可以从多项式拟合中排除ROF的部分，例如被确定为与相关光谱峰相关联的部分。

公开(公告)号：US08664954B2

公开(公告)日：2014-03-04

申请号：US13257091

申请日：2009-03-31

申请人： Stefan Hetzer ,  Toralf Mildner ,  Harald Moeller

发明人： Stefan Hetzer ,  Toralf Mildner ,  Harald Moeller

IPC分类号： G01V3/00

CPC分类号： G01R33/5616 ,  G01R33/4806 ,  G01R33/4818 ,  G01R33/482 ,  G01R33/4828 ,  G01R33/483 ,  G01R33/485 ,  G01R33/5607 ,  G01R33/56341 ,  G01R33/56366 ,  G01R33/56536 ,  G01R33/56554 ,  G01R33/56563

摘要： A method of magnetic resonance imaging of an object comprises the steps of arranging the object in a stationary magnetic field, subjecting the object to an excitation and encoding sequence of magnetic field gradients resulting in k-space sampling in two segments along the phase encoding direction, wherein the encoding sequence of the magnetic field gradients is selected such that the two segments in k-space are sampled along trajectories beginning with a central k-space line through the k-space center and continuing to opposite k-space borders of the two segments, collecting magnetic resonance signals created in the object, and reconstructing an image of the object based on the magnetic resonance signals, wherein one central k-space line is sampled in both of the two k-space segments, and intersegment phase and/or intensity deviations are corrected in both k-space segments using the magnetic resonance signals collected along the central k-space line. Furthermore, an imaging device for magnetic resonance imaging of an object is described.

摘要翻译： 物体的磁共振成像的方法包括以下步骤：将物体放置在固定磁场中，使物体受到磁场梯度的激励和编码序列的影响，导致沿着相位编码方向的两段中的k空间采样， 其中选择磁场梯度的编码序列使得k空间中的两个片段沿着通过k空间中心的中心k空间线开始的轨迹被采样，并且连续到两个片段的相反k空间边界 收集在物体中产生的磁共振信号，以及基于磁共振信号重建物体的图像，其中一个中心k空间线在两个k空间段中的两个采样，并且分段相位和/或强度 使用沿着中心k空间线收集的磁共振信号在两个k空间段中校正偏差。 此外，描述了用于物体的磁共振成像的成像装置。