公开(公告)号：US06294646B1

公开(公告)日：2001-09-25

申请号：US09525547

申请日：2000-03-14

申请人： James H. Wang ,  David M. Schertz

发明人： James H. Wang ,  David M. Schertz

IPC分类号： C08G6308

摘要： The present invention is a water-responsive blend of a polylactide and a polyvinyl alcohol. The present invention includes films and personal care articles comprising a blend of a polyvinyl alcohol and a polylactide and includes a method of making such films and articles and a method of varying the water responsiveness of such films and articles. In a preferred embodiment, the compositions, films and articles comprise a blend of polyvinyl alcohol and modified polylactide. The compositions and films described herein are useful as a component in flushable and degradable articles.

公开(公告)号：US06194539B1

公开(公告)日：2001-02-27

申请号：US08560110

申请日：1995-11-17

申请人： Hideki Matsui

发明人： Hideki Matsui

IPC分类号： C08G6308

CPC分类号： C09D11/03 ,  C08G63/6852 ,  C08G63/912 ,  C09B67/0089 ,  C09D7/45 ,  C09D17/002

摘要： Disclosed are a novel polylactone having amino groups and to a process for the preparation thereof. The polylactone having amino groups of the present invention is excellent in color hue, and it can be preferably employed in fields such as coatings, inks, ultraviolet ray curable or electronic beam curable resins, etc., in which the color hue becomes a serious problem. Furthermore, disclosed are a novel compound having amino groups and to a process for the preparation thereof. The compound having amino groups of the present invention can be preferably employed as a dispersant for pigments in a coating composition or a printing ink composition.

摘要翻译： 公开了具有氨基的新型聚内酯及其制备方法。 本发明的具有氨基的聚内酯的色调优异，可以优选用于涂料，油墨，紫外线固化型或电子束固化性树脂等领域，其中色调变成严重问题 此外，公开了具有氨基的新化合物及其制备方法。 本发明的具有氨基的化合物可以优选用作涂料组合物或印刷油墨组合物中颜料的分散剂。

公开(公告)号：US06187901B1

公开(公告)日：2001-02-13

申请号：US09367381

申请日：1999-08-13

申请人： Jukka Koskinen ,  Johan-Fredrik Selin ,  Nikitas Katsaras ,  Kari Kaariainen

发明人： Jukka Koskinen ,  Johan-Fredrik Selin ,  Nikitas Katsaras ,  Kari Kaariainen

IPC分类号： C08G6308

CPC分类号： C08G63/08 ,  C08G63/90

摘要： The invention relates to a method for the removal of lactide from polylactide and recovery of lactide from a lactide-containing gas by cooling the hot lactide-containing gas, wherein a polymer melt traveling through a nozzle forms thin threads the surface area of which is so large that in a normal-pressure or vacuum evaporator the lactide evaporates from the polymer rapidly into a hot carrier-gas flow and the polymer settles under gravity onto a collecting device. A hot lactide-containing gas is cooled rapidly to a temperature below 100° C., whereupon the lactide crystallizes from gas, forming lactide crystals, which are separated from the gas.

摘要翻译： 本发明涉及从聚丙交酯中除去丙交酯并从含丙交酯的气体中回收丙交酯的方法，其中，通过冷却含丙交酯的气体，其中通过喷嘴流动的聚合物熔体形成薄的螺纹，其表面积如此 大的是，在常压或真空蒸发器中，丙交酯从聚合物快速蒸发成热载气流，聚合物在重力作用下沉降到收集装置上。 将含热丙交酯的气体快速冷却至低于100℃的温度，随后丙交酯从气体中结晶，形成与气体分离的丙交酯晶体。

公开(公告)号：US06747121B2

公开(公告)日：2004-06-08

申请号：US09945704

申请日：2001-09-05

申请人： Sylwester Gogolewski

发明人： Sylwester Gogolewski

IPC分类号： C08G6308

CPC分类号： C08G63/08 ,  A61L27/18 ,  A61L31/06 ,  Y10S606/91 ,  C08L67/04

摘要： The present invention relates in general to implantable, resorbable copolymers containing L-lactide and glycolide repeat units, and in particular to terpolymers containing L-lactide, glycolide, and one other type of repeat unit selected from the group consisting of D-lactide, D,L-lactide, and &egr;-caprolactone. Medical devices for in vivo implantation applications containing such implantable, resorbable copolymers are also described, as well as methods for making such copolymers and devices.

摘要翻译： 本发明一般涉及含有L-丙交酯和乙交酯重复单元的可植入的可再吸收的共聚物，特别涉及含有L-丙交酯，乙交酯和一种其它类型的重复单元的三元共聚物，所述重复单元选自D-丙交酯，D ，L-丙交酯和ε-己内酯。 还描述了含有这种可植入的可再吸收共聚物的体内植入应用的医疗装置，以及制备这种共聚物和装置的方法。

公开(公告)号：US06730772B2

公开(公告)日：2004-05-04

申请号：US09886394

申请日：2001-06-22

申请人： Venkatram P. Shastri

发明人： Venkatram P. Shastri

IPC分类号： C08G6308

CPC分类号： C08G65/22 ,  B33Y70/00 ,  C08G63/664 ,  C08L67/00 ,  C08L71/02 ,  C08L2205/05 ,  C08L2666/18

摘要： A polymer of a ring-opened functionalized epoxide is formed by the polymerization of a functionalized epoxide monomer having the structure E-CHR-G wherein E represents an epoxide group, R is hydrogen or an alkyl group, and G is a derivatizable group such as an unsaturated functionality or ester substituent.

摘要翻译： 通过具有结构E-CHR-G的官能化环氧化物单体的聚合形成开环官能化环氧化物的聚合物，其中E表示环氧基，R是氢或烷基，G是可衍生的基团，例如 不饱和官能团或酯取代基。

公开(公告)号：US06593434B1

公开(公告)日：2003-07-15

申请号：US09806728

申请日：2001-04-24

申请人： Jun Watanabe

发明人： Jun Watanabe

IPC分类号： C08G6308

CPC分类号： C08K5/15 ,  C08G63/60 ,  C08G63/91 ,  C08G2261/126 ,  C08K5/0091 ,  C08K5/09 ,  C08K5/29 ,  C08L63/00 ,  C08L67/00 ,  H05B3/56 ,  C08L2666/22

摘要： The invention provides methods for the preparation of polyester block copolymers, by reacting crystalline aromatic polyesters with lactones and/or epoxides. By using a slight excess of lactone in the reaction, and a subsequent solid-phase polycondensation reaction, the method generates high-molecular weight block copolymers of low crystallinity. Methods are also provided for generating polyester block copolymers by melt-mixing or kneading polyester block copolymers with epoxides in the solid phase.

摘要翻译： 本发明提供了通过使结晶芳族聚酯与内酯和/或环氧化物反应来制备聚酯嵌段共聚物的方法。 通过在反应中使用少量过量的内酯和随后的固相缩聚反应，该方法产生低结晶度的高分子量嵌段共聚物。 还提供了通过将聚酯嵌段共聚物与固相中的环氧化物熔融混合或捏合来生成聚酯嵌段共聚物的方法。

公开(公告)号：US06476156B1

公开(公告)日：2002-11-05

申请号：US09778081

申请日：2001-02-07

申请人： Young Ha Kim ,  Soo Hyun Kim ,  Ki Dong Park ,  Soo-Hong Lee

发明人： Young Ha Kim ,  Soo Hyun Kim ,  Ki Dong Park ,  Soo-Hong Lee

IPC分类号： C08G6308

CPC分类号： C08G65/3324 ,  C08G63/664 ,  C08L71/02 ,  C08L2666/18

摘要： The present invention relates to polyethyleneglycol/polylactide(or polyglycolide or polycaprolactone)/polyethyleneglycol triblock copolymers with an enhanced reactivity, and process for their preparation. More specifically, the present invention is directed to triblock copolymers that are obtained by the process comprising the step of synthesizing a polylactide(or polyglycolide or polycaprolactone) having hydroxy groups at both ends and the step of coupling said polylactide with polyethyleneglycol having an acylhalide group of a high reactivity at one of its ends, and the process for preparing the same Since the triblock copolymer according to the present invention has an ester structure with good biocompatibility, it can be applied extensively for biomaterials used in tissue engineering, in a matrix that slowly releases drugs, etc.

摘要翻译： 本发明涉及具有增强反应性的聚乙二醇/聚丙交酯（或聚乙交酯或聚己内酯）/聚乙二醇三嵌段共聚物及其制备方法。 更具体地说，本发明涉及三嵌段共聚物，该三嵌段共聚物通过包括以下步骤获得的方法：合成在两端具有羟基的聚丙交酯（或聚乙交酯或聚己内酯）和将所述聚交酯与具有酰卤基团的聚乙二醇 在其一端的高反应性及其制备方法由于本发明的三嵌段共聚物具有良好的生物相容性的酯结构，因此可广泛用于组织工程中使用的生物材料 释放药物等

公开(公告)号：US06429280B1

公开(公告)日：2002-08-06

申请号：US09763242

申请日：2001-02-20

申请人： Shouji Hiraoka ,  Hitoshi Tsuboi ,  Masayuki Sakai

发明人： Shouji Hiraoka ,  Hitoshi Tsuboi ,  Masayuki Sakai

IPC分类号： C08G6308

CPC分类号： C08G63/80 ,  B29B9/12 ,  B29B9/16 ,  B29K2995/0041 ,  C08G63/06 ,  C08G63/78

摘要： A process for preparing a polyhydroxycarboxylic acid having a weight average molecular weight of 50,000 to 1,000,000, which comprises a crystallizing step comprising (A) a step of heating pellets of a polyhydroxycarboxylic acid having a weight average molecular weight of 2,000 to 100,000 under stirring to a temperature from glass transition point or higher to a melting point or lower and heating until a defined result is attained, and (B) a step of heating the polyhydroxycarboxylic acid to a temperature of solid phase polycondensation reaction temperature, and a solid phase polycondensation reaction step of reacting the crystallized polyhydroxycarboxylic acid at an endothermic start temperature or lower of an endothermic peak as recognized upon temperature elevation analysis of the crystallized polyhydroxycarboxylic acid by using a differential scanning calorimeter.

摘要翻译： 一种制备重均分子量为50,000〜1,000,000的聚羟基羧酸的方法，其包括结晶步骤，其包括（A）在搅拌下将重均分子量为2,000至100,000的聚羟基羧酸的颗粒加热至 温度从玻璃化转变点以上到熔点以下，加热直到达到规定的结果，（B）将聚羟基羧酸加热到固相缩聚反应温度的步骤，和固相缩聚反应步骤 使结晶的聚羟基羧酸在吸热峰的吸热开始温度或更低的温度下反应，通过使用差示扫描量热计对结晶的聚羟基羧酸进行升温分析。

公开(公告)号：US06376643B1

公开(公告)日：2002-04-23

申请号：US09710038

申请日：2000-11-08

申请人： Wen Chung Chang ,  Wei-Hsiang Sun

发明人： Wen Chung Chang ,  Wei-Hsiang Sun

IPC分类号： C08G6308

CPC分类号： C08G63/823 ,  C08G63/08

摘要： This invention relates to a method of polymerization of lactide or glycolide (GA) monomers and in particular to a method of polymerizing one type of the monomers or two types of the monomers using alkyl aluminum catalyst to proceed with bulk or solution polymerization to prepare biodegradable homopolymers or copolymers, and high-molecular-weight homopolymers of polylactide (PLA), polyglycolide (PGA), or copolymers of lactide/glycolide prepared thereof.

摘要翻译： 本发明涉及丙交酯或乙交酯（GA）单体的聚合方法，特别涉及一种使用烷基铝催化剂聚合一种单体或两种单体的方法，以进行本体或溶液聚合以制备可生物降解的均聚物 或共聚物，以及聚丙交酯（PLA），聚乙交酯（PGA）的高分子量均聚物或其制备的丙交酯/乙交酯的共聚物。

公开(公告)号：US06362308B1

公开(公告)日：2002-03-26

申请号：US09635677

申请日：2000-08-10

申请人： Chiem V. Pham

发明人： Chiem V. Pham

IPC分类号： C08G6308

CPC分类号： C08G63/823 ,  A61K9/1647 ,  A61K38/09 ,  A61K38/27 ,  A61K38/28 ,  C08G63/08 ,  Y10T428/2982 ,  Y10T428/2985

摘要： Copolymers of lactide and glycolide with high glycolide content. The average glycolate block length is less then about 3, which allows the copolymer to be soluble in slightly polar solvents such as methylene chloride.

摘要翻译： 具有高乙交酯含量的丙交酯和乙交酯的共聚物。 平均乙醇酸酯嵌段长度小于约3，这允许共聚物可溶于微量极性溶剂如二氯甲烷。