公开(公告)号：US20250102511A1

公开(公告)日：2025-03-27

申请号：US18971325

申请日：2024-12-06

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Alexander K. TUCKER-SCHWARTZ ,  George SIGAL

IPC: G01N33/58 ,  G01N21/66

Abstract: The present disclosure provides compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the disclosure relates to an assay composition for detecting luminescence, which comprises an alkyl diethanolamine, for example, N-butyldiethanolamine (BDEA). In emodiments, the assay composition comprises 2-dibutylaminoethanol (BDAE).

公开(公告)号：US20250043906A1

公开(公告)日：2025-02-06

申请号：US18793305

申请日：2024-08-02

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Manish KOCHAR ,  Gary KRIVOY ,  Aaron H. LEIMKUEHLER

IPC: F16M13/02 ,  F16M11/14 ,  F16M11/20

Abstract: The invention relates to a load support unit for holding and adjusting the orientation of the load. The load support unit includes a lower arm, a upper arm, a mounting swivel, a swivel joint, a knuckle joint and a rotational joint. The mounting swivel allows the load support unit to rotate relative to its surroundings, the swivel joint allows the upper arm to rotate relative to the lower arm, the knuckle joint allows the upper arm to pivot in a rotational direction relative to the lower arm, and the rotational joint allows the load to rotate about the upper arm.

公开(公告)号：US12216117B2

公开(公告)日：2025-02-04

申请号：US17553441

申请日：2021-12-16

Applicant: Meso Scale Technologies, LLC.

Inventor： Sudeep Kumar ,  George Sigal ,  Michael Tsionsky

IPC: G01N33/543 ,  C12Q1/6823 ,  C12Q1/6832 ,  C12Q1/6834 ,  G01N33/53

Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.

公开(公告)号：US20240427071A1

公开(公告)日：2024-12-26

申请号：US18820772

申请日：2024-08-30

Applicant: Meso Scale Technologies, LLC.

Inventor： Cecilia Zimmerman ,  Jules VanDersarl

IPC: F21V8/00 ,  F21V3/00 ,  F21Y113/10 ,  F21Y115/10 ,  G08B5/36

Abstract: The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.

公开(公告)号：US20240409983A1

公开(公告)日：2024-12-12

申请号：US18734455

申请日：2024-06-05

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： David ROUTENBERG ,  Evan GIZZIE ,  Alexander K. TUCKER-SCHWARTZ ,  George SIGAL ,  Khondaker RAHMAN ,  Deepak NANJAPPA

IPC: C12Q1/6823 ,  C12Q1/6806 ,  C12Q1/6834 ,  C12Q1/6851

Abstract: Provided herein are methods for analyzing a sample for an analyte using proximity-based extension, such as proximity extension strand displacement. Also provided are multiplexed methods for analyzing a sample using proximity-based extension. Provided herein are methods for screening for pairwise combination of binding moieties, for use in a sandwich-type assay. Also provided are compositions that find use in the present methods.

公开(公告)号：US12163954B2

公开(公告)日：2024-12-10

申请号：US17132380

申请日：2020-12-23

Applicant: Meso Scale Technologies, LLC.

Inventor： Anahit Aghvanyan ,  Eli N. Glezer ,  John Kenten ,  George Sigal ,  Martin Stengelin

IPC: C12Q1/6804 ,  G01N21/66 ,  G01N21/76 ,  G01N21/77 ,  G01N33/53 ,  G01N33/533 ,  G01N33/543 ,  G01N33/569 ,  G01N33/58

Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.

公开(公告)号：US12146877B2

公开(公告)日：2024-11-19

申请号：US17082799

申请日：2020-10-28

Applicant: Meso Scale Technologies, LLC.

Inventor： Mark Billadeau ,  Paul Freese ,  Alan Kishbaugh ,  Gisbert Spieles ,  Nicholas Fox-Lyon

IPC: G01N33/543 ,  C12Q1/00 ,  G01N21/66 ,  G01N21/69 ,  G01N21/76

Abstract: The specification provides an assay electrode including a composite containing a matrix and a multiplicity of graphene particles dispersed therein.

公开(公告)号：USD1047339S1

公开(公告)日：2024-10-15

申请号：US29826124

申请日：2022-02-09

Applicant: Meso Scale Technologies, LLC.

Designer： Jacob N. Wohlstadter ,  Rodger Darin Osborne ,  Jennifer Parker ,  Aaron Leimkuehler ,  Manish Kochar ,  Peter Bosco ,  Michael Wade ,  Gary Krivoy ,  Charles M. Clinton

Abstract: FIG. 1 is a perspective view of a shuttle showing our new and ornamental design;
FIG. 2 is an alternate perspective view thereof;
FIG. 3 is front elevation view thereof;
FIG. 4 is a rear elevation view thereof;
FIG. 5 is a side elevation view thereof;
FIG. 6 is an opposite side elevation view thereof; and,
FIG. 7 is a top plan view thereof.
The portions of the shuttle shown in broken lines shown in the figures attached hereto form no part of the claimed design. No bottom view of the claimed design has been included because this view only shows unclaimed portions of the design.

公开(公告)号：US12105104B2

公开(公告)日：2024-10-01

申请号：US17321099

申请日：2021-05-14

Applicant: Meso Scale Technologies, LLC.

Inventor： Jennifer Parker ,  Slavi Mirtchev ,  Manish Kochar ,  Robert Causey

IPC: G01N35/00 ,  B01L3/00 ,  B65D43/02 ,  B65D43/26 ,  B65D51/24

CPC classification number: G01N35/0099 ,  B01L3/5055 ,  B01L3/50853 ,  B01L3/5457 ,  B65D43/0214 ,  B65D43/26 ,  B65D51/243 ,  B01L2200/026 ,  B01L2300/044 ,  B65D2543/00296 ,  B65D2543/00333 ,  B65D2543/0037 ,  B65D2543/00824

Abstract: The present disclosure relates to an automated assay system adapted to receive consumables in the conduct of an assay. The assay system includes at least one of a loading cart, a door support system, a waste storage unit, and a robotic subsystem. The loading cart is configured to organize and transport consumables necessary for the performance of the assay system. The door support system is configured to maintain stability of doors of the automated assay system. The waste storage unit is configured to provide convenient disposal of consumables associated with the automated assay system. The robotic subsystem is configured to transport consumables within the automated assay system.

公开(公告)号：US12103735B2

公开(公告)日：2024-10-01

申请号：US17534773

申请日：2021-11-24

Applicant: Meso Scale Technologies, LLC. ,  Merrill's Packaging, Inc.

Inventor： Nataliya Lavrykova-Marrain ,  Jonathan Vu Tran

IPC: B65D25/10 ,  B65D43/16 ,  B65D85/44

CPC classification number: B65D25/107 ,  B65D43/162 ,  B65D43/163 ,  B65D85/44 ,  B65D2543/00296

Abstract: The disclosure is directed to a package for containing a plurality of substantially rectangular assay plates, each plate having a peripheral flange. In one embodiment, the package comprises a cavity having extending therein one or more sloped buttress elements spaced across at least a portion of a top corner, and one or more adjacent protrusions extending from the bottom and at least partially up one or both sidewalls, each set of protrusions forming grooves therebetween into which fit the flanges of respective assay plates. The package can comprise a transparent polymer through which product information located on the assay plates can be read or scanned.