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公开(公告)号：US20240219307A1
公开(公告)日：2024-07-04
申请号：US18429280
申请日：2024-01-31
Applicant: Meso Scale Technologies, LLC.
Inventor： Charles M. CLINTON , Eli N. GLEZER , Sharon WEST , George SIGAL , Carl STEVENS , Michael L. VOCK
CPC classification number: G01N21/76 , G01N21/69 , G01N35/0092 , G01N35/028 , G01N2035/00524 , G01N2035/0425 , G01N35/1079 , Y10T436/114165
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US20230184768A1
公开(公告)日：2023-06-15
申请号：US17997267
申请日：2021-04-30
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Jacob N. WOHLSTADTER , George SIGAL , Anu MATHEW , James WILBUR , Jeffery DEBAD , Christopher CAMPBELL , Hans BIEBUYCK , Priscilla KRAI , Alan KISHBAUGH , Leonid DZANTIEV , Christopher SHELBURNE , Pu LIU , Paul GOODWIN
IPC: G01N33/569 , G01N33/68
CPC classification number: G01N33/56983 , G01N33/6854 , G01N2333/11 , G01N2333/165 , G01N2469/20
Abstract: The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
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公开(公告)号：US20210291168A1
公开(公告)日：2021-09-23
申请号：US17215962
申请日：2021-03-29
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. GLEZER , Sudeep KUMAR , Pankaj OBEROI , George SIGAL , Michael TSIONSKY
IPC: B01L3/00 , C12Q1/6804 , G01N33/68 , G01N33/543 , C12Q1/6816 , C12Q1/6876
Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
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公开(公告)号：US20210190778A1
公开(公告)日：2021-06-24
申请号：US17132380
申请日：2020-12-23
Applicant: Meso Scale Technologies, LLC.
Inventor： Anahit AGHVANYAN , Eli N. GLEZER , John KENTEN , George SIGAL , Martin STENGELIN
IPC: G01N33/543 , G01N33/569 , G01N33/53 , G01N33/533 , C12Q1/6804 , G01N21/66 , G01N21/76 , G01N21/77 , G01N33/58
Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
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公开(公告)号：US20190391170A1
公开(公告)日：2019-12-26
申请号：US16319731
申请日：2017-01-20
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： Manish KOCHAR , Peter J. BOSCO , Ian D. CHAMBERLIN , Bandele JEFFREY-COKER , Eric M. JONES , Gary l. KRIVOY , Aaron H. LEIMKUEHLER , Pei-Ming WU , Kim-Xuan NGUYEN , Pankaj OBEROI , Louis W. PANG , Jennifer PARKER , Victor PELLICIER , Nick SAMMONS , George SIGAL , Jacob WOHLSTADTER , Mike VOCK , Stanley T. SMITH , Carl C. STEVENS , Roger D. OSBORNE , Kenneth PAGE , Michael T. WADE , Jon WILLOUGHBY , Lei WANG , Don E. KRUEGER
Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
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Patent Agency Ranking
公开(公告)号：US20240159766A1
公开(公告)日：2024-05-16
申请号：US18545200
申请日：2023-12-19
Applicant: Meso Scale Technologies, LLC.
Inventor： Charles M. CLINTON , Eli N. GLEZER , Bandele JEFFREY-COKER , Sandor L. KOVACS , Sudeep M. KUMAR , George SIGAL , Carl STEVENS , Michael VOCK
CPC classification number: G01N33/582 , B01L3/50255 , B01L3/5085 , B67B7/24 , G01N21/6452 , G01N21/66 , G01N33/5302 , G01N35/028 , G01N35/1011 , G01N35/1079 , G01N35/1081 , G01N2035/0405 , G01N35/1002 , G01N35/109 , Y10T83/9314
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US20220381780A1
公开(公告)日：2022-12-01
申请号：US17749721
申请日：2022-05-20
Applicant: Meso Scale Technologies, LLC. , The United States of America,as represented by the Secretary,Department of Health and Human Services
Inventor： Jacob N. WOHLSTADTER , George SIGAL , James WILBUR , Jeffery DEBAD , Hans BIEBUYCK , Priscilla KRAI , Alan KISHBAUGH , Leonid DZANTIEV , Christopher SHELBURNE , Christopher CAMPBELL , Anastasia AKSYUK , Adrian MCDERMOTT , Sarah O'CONNELL , Sandeep NARPALA , Chien Li LIN
IPC: G01N33/569 , G01N33/543 , G01N33/58
Abstract: The invention relates to methods and kits for determining a SARS-CoV-2 strain in a sample. The invention further provides methods and kits for detecting a single nucleotide polymorphism (SNP) in a target nucleic acid, wherein the target nucleic acid is a SARS-CoV-2 nucleic acid. The invention further provides methods and kits for detecting one or more antibody biomarkers in a sample.
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公开(公告)号：US20220221449A1
公开(公告)日：2022-07-14
申请号：US17572280
申请日：2022-01-10
Applicant: MESO SCALE TECHNOLOGIES, LLC.
Inventor： John JOERN , George SIGAL
IPC: G01N33/543 , G06F17/18
Abstract: Systems and methods for calibrating sample assays are provided. Systems may include assay devices and components for carrying out calibration and sample assays. Systems may further include processing components and storage units configured for receiving calibration information, determining calibration models and parameters, and applying calibration parameters to sample data. Systems may further include components for operating in a networked environment. Methods may include techniques and processes for carrying out calibration and sample assays, determining calibration models and parameters, and applying calibration parameters to sample data.
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公开(公告)号：US20220099661A1
公开(公告)日：2022-03-31
申请号：US17434938
申请日：2020-02-28
Applicant: Meso Scale Technologies, LLC.
Inventor： John KENTEN , Mikayla HIGGINS , George SIGAL
IPC: G01N33/533 , C07F15/00 , G01N33/58 , C12Q1/6816 , G01N21/64 , G01N21/66
Abstract: The present invention is directed to assay methods and compounds and kits used in such assays.
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公开(公告)号：US20210407692A1
公开(公告)日：2021-12-30
申请号：US17359479
申请日：2021-06-25
Applicant: Meso Scale Technologies, LLC.
Inventor： Jacob N. WOHLSTADTER , Michael VOCK , Charles M. CLINTON , George SIGAL
Abstract: Provided herein are systems, methods, and apparatuses for providing a real-time global bio-surveillance and response solution. The systems and apparatuses may include one or more sentinel subsystems and one or more surge subsystems that each include a real-time, cloud-based, distributed, interconnected set of hardware, software, and/or firmware for comprehensive surveillance, complete detection, and immediate response various to biological, chemical, and/or bio-chemical anomalies, for example, a new or emerging pathogen or other health condition.
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