公开(公告)号：US4918250A

公开(公告)日：1990-04-17

申请号：US341447

申请日：1989-04-21

Applicant: Robert W. Mason ,  Peter C. Imm ,  Kent J. Bordelon

Inventor： Robert W. Mason ,  Peter C. Imm ,  Kent J. Bordelon

IPC: C07C201/08 ,  C07C201/16 ,  C07C205/06

CPC classification number: C07C201/16 ,  C07C201/08

Abstract: This invention relates to a process for nitrating toluene to dinitrotoluene and phase separation of the product using an inorganic salt as a phase separation agent.

Abstract translation: 本发明涉及使用无机盐作为相分离剂将甲苯硝化成二硝基甲苯和相分离的方法。

公开(公告)号：US4910345A

公开(公告)日：1990-03-20

申请号：US231740

申请日：1988-08-12

Applicant: Willi Streicher ,  Heinz U. Blank

Inventor： Willi Streicher ,  Heinz U. Blank

IPC: C07C67/00 ,  C07C201/00 ,  C07C201/16 ,  C07C205/44

CPC classification number: C07C201/16

Abstract: Crude nitrobenzaldehyde can be substantially purified from the undesired positional isomers if a treatment with 100-10,000% by weight of water and 1-30% by weight of an emulsifier, all with reference to the dry weight of the crude nitrobenzaldehyde, is undertaken at a temperature of 30.degree.-140.degree. C. and at a pH of 3-14.

Abstract translation: 如果使用100-10,000重量％的水和1-30重量％的乳化剂处理，全部参照粗制硝基苯甲醛的干重，就可以从不希望的位置异构体中纯化粗硝基苯甲醛。 温度为30°-140℃，pH为3-14。

公开(公告)号：US4863587A

公开(公告)日：1989-09-05

申请号：US171372

申请日：1988-03-21

Applicant: Takashi Tonari ,  Yasuhiko Ikeda

Inventor： Takashi Tonari ,  Yasuhiko Ikeda

IPC: C07C7/04 ,  C07C1/00 ,  C07C7/20 ,  C07C15/46 ,  C07C67/00 ,  C07C201/00 ,  C07C201/16 ,  C07C205/23 ,  C07C251/46

CPC classification number: C07C201/16 ,  C07C7/20

Abstract: A phenolic polymerization inhibitor is recovered from a styrene distillation residue containing the phenolic polymerization inhibitor by a method which comprises extracting the inhibitor from the styrene distillation residue with an oxygen-containing organic solvent having not more than 6 carbon atoms, adding an aromatic hydrocarbon solvent to the oxygen-containing organic solvent phase consequently obtained, and subjecting the resultant mixture to distillation thereby separating the mixture into a solution of the phenolic polymerization inhibitor in the aromatic hydrocarbon solvent and the oxygen-containing organic solvent. The recovered solution is put to use as a polymerization inhibitor either in the unmodified form or in a form separated from the aromatic hydrocarbon solvent.

公开(公告)号：US4786731A

公开(公告)日：1988-11-22

申请号：US81519

申请日：1987-08-05

Applicant: John W. Russell

Inventor： John W. Russell

IPC: C07B57/00 ,  C07C201/16 ,  C07D213/64 ,  C07D213/643 ,  C07D241/44 ,  C07D241/36 ,  C07D211/72

CPC classification number: C07D213/643 ,  C07C201/16 ,  C07C213/10 ,  C07C253/34 ,  C07C51/493 ,  C07D241/44

Abstract: A method for the chromatographic resolution and analysis of the enantiomers of 2-(phenyl or phenoxy)propionic acids or the C.sub.1 -C.sub.4 alkyl esters thereof which comprises converting a racemic or partially resolved mixture of said 2-(phenyl or phenoxy)propionic acids or the C.sub.1 -C.sub.4 alkyl esters thereof to a pair of diastereomeric 2-amino-1-alkanol derivatives by reaction with an optically active 2-amino-1-alkanol, and analyzing the diastereomeric mixture by gas chromatography.

Abstract translation: 2-（苯基或苯氧基）丙酸或其C 1 -C 4烷基酯的对映异构体的色谱拆分和分析方法，其包括将所述2-（苯基或苯氧基）丙酸的外消旋或部分拆分的混合物或 通过与光学活性2-氨基-1-链烷醇反应，将其C1-C4烷基酯与一对非对映异构体2-氨基-1-链烷醇衍生物反应，并通过气相色谱法分析非对映体混合物。

公开(公告)号：US4717778A

公开(公告)日：1988-01-05

申请号：US782345

申请日：1985-10-01

Applicant: Hermann A. Zinnen ,  Thad S. Franczyk

Inventor： Hermann A. Zinnen ,  Thad S. Franczyk

IPC: C07C201/16 ,  C07C79/10

CPC classification number: C07C201/16

Abstract: This invention comprises a process for separating the minor dinitrotoluene isomers, 2,3-dinitrotoluene and 3,4-dinitrotoluene from a feed mixture comprising 2,4- and 2,6-dinitrotoluene, and the minor isomers, which process comprises contacting the mixtures at adsorption conditions with an adsorbent comprising a Y type, or dealuminated Y type, zeolite, cation exchanged with Na, Ca or H, thereby selectively adsorbing the 2,3- and 3,4- isomers or 2,4- and 2-6 isomers, respectively. The remainder of the feed mixture is removed from the adsorbent and the minor isomers are recovered by desorption at desorption conditions with a desorbent material comprising an alcohol, ketone or an ester.

Abstract translation: 本发明包括从包含2,4-和2,6-二硝基甲苯的进料混合物和次要异构体中分离次要二硝基甲苯异构体，2,3-二硝基甲苯和3,4-二硝基甲苯的方法，该方法包括使混合物 在含有Y型或脱铝Y型沸石，沸石，与Na，Ca或H交换的阳离子的吸附剂的吸附条件下，从而选择性吸附2,3-和3,4-异构体或2,4-和2-6 异构体。 进料混合物的其余部分从吸附剂中除去，并且通过在解吸附条件下用包含醇，酮或酯的解吸剂材料解吸来回收次要异构体。

公开(公告)号：US4709082A

公开(公告)日：1987-11-24

申请号：US789640

申请日：1985-10-21

Applicant: Yasuhiro Takahashi ,  Kazutaka Arai ,  Yoshio Ohara ,  Hiroo Matsumoto ,  Syuuzi Tsuchiya

Inventor： Yasuhiro Takahashi ,  Kazutaka Arai ,  Yoshio Ohara ,  Hiroo Matsumoto ,  Syuuzi Tsuchiya

IPC: C07C51/487 ,  C07C201/16 ,  C07C205/43 ,  C07C69/76

CPC classification number: C07C201/12 ,  C07C201/16 ,  C07C51/487 ,  C07C67/14 ,  C07C67/52 ,  C07C69/612 ,  C07B2200/07

Abstract: 2-Phenylpropoionic acid ester of Formula (I): ##STR1## wherein R represents p-nitrophenyl group, .beta.-naphthyl group or 2-(.beta.-naphthyl)ethyl group.Optical resolution of the above is carried out by preferential crystallization by seeding either one of the optical isomers into a super-saturated solution of a racemic modification thereof or a mixture of the optical isomers thereof. The efficiency of the optical resolution can be increased by optional addition of a recemizing agent comprising a strongly basic amine or an alcholate.

Abstract translation: 式（I）的2-苯基丙酸酯：其中R表示对硝基苯基，β-萘基或2-（β-萘基）乙基。 上述的光学拆分通过优选结晶通过将任一种光学异构体接种到其外消旋变体的超饱和溶液或其旋光异构体的混合物中进行。 通过任选地加入包含强碱性胺或醇酸盐的接收剂可以提高光学拆分的效率。

公开(公告)号：US4700011A

公开(公告)日：1987-10-13

申请号：US782229

申请日：1985-09-30

Applicant: Dale G. Pillsbury

Inventor： Dale G. Pillsbury

IPC: C07C201/12 ,  C07C201/16 ,  C07C205/38 ,  C07C43/275 ,  C07C79/35

CPC classification number: C07C201/16 ,  C07C201/12 ,  C07C213/02

Abstract: Di(nitrophenyl) ethers are prepared by the reaction of a halogeno-nitrophenyl compound with a base wherein the water in the reaction system is removed during the reaction. The reaction can be advantageously carried out at two different temperatures. The use of a molar excess of the halogeno-nitrophenyl compound improves the yield of di(nitrophenyl) ether. Crude di(nitrophenyl) ether is purified by extraction into a non-aqueous solvent using a dual temperature method to maintain the ether in the liquid phase.

Abstract translation: 二（硝基苯基）醚通过卤代 - 硝基苯基化合物与反应中除去反应体系中的水的碱反应来制备。 反应可以有利地在两个不同的温度下进行。 使用摩尔过量的卤代 - 硝基苯基化合物可提高二（硝基苯基）醚的产率。 粗二（硝基苯基）醚通过使用双温法萃取到非水溶剂中以将乙醚保持在液相中来纯化。

公开(公告)号：US4650912A

公开(公告)日：1987-03-17

申请号：US716061

申请日：1985-03-26

Applicant: Michael C. Pohl ,  Richard V. C. Carr ,  John E. Sawicki

Inventor： Michael C. Pohl ,  Richard V. C. Carr ,  John E. Sawicki

IPC: C07C201/16 ,  C07C79/10

CPC classification number: C07C201/16

Abstract: In a method for denitrifying the nitric acid- and nitrous acid-containing spent acid phase from the nitration of an aromatic hydrocarbon by the mixed acid process which comprises forming a denitrification reaction medium by contacting the spent acid phase with an aromatic hydrocarbon under nitration reaction conditions to recover the nitric acid by the formation of a nitroaromatic hydrocarbon, the improvement which comprises(a) adding an amount of aromatic hydrocarbon which is slightly less than or equal to the stoichiometric amount necessary to deplete the spent acid phase of nitric acid,(b) photometrically monitoring the denitrification reaction medium for the appearance of a dark red to black color, and(c) upon detection of such color, adjusting the aromatic hydrocarbon:nitric acid molar ratio in the denitrification reaction medium to eliminate the color by reducing the aromatic hydrocarbon feed rate, or adding nitric acid to the denitrification reaction medium.

Abstract translation: 在通过混合酸法使芳族烃硝化反硝化含硝酸和亚硝酸的废酸相的方法中，其包括通过在硝化反应条件下使废酸相与芳族烃接触来形成反硝化反应介质 通过形成硝基芳族烃来回收硝酸，其改进包括（a）加入一定量的少于或等于耗尽硝酸废酸所需化学计量的芳烃，（b ）用于对脱氮反应介质进行光度监测，以显示深红色至黑色，以及（c）在检测到这种颜色后，调节反硝化反应介质中的芳烃：硝酸摩尔比以通过还原芳族化合物来消除颜色 烃进料速率，或向脱氮反应介质中加入硝酸。

公开(公告)号：US4506089A

公开(公告)日：1985-03-19

申请号：US586668

申请日：1984-03-06

Applicant: Alfred Hackenberger ,  Manfred Patsch ,  Manfred Gaeng

Inventor： Alfred Hackenberger ,  Manfred Patsch ,  Manfred Gaeng

IPC: C07C201/16 ,  C07C76/06 ,  C07C79/46

CPC classification number: C07C201/16

Abstract: Methyl m-nitrobenzoate is prepared by a process in which an isomer mixture is treated with from 10 to 1000% by weight of water in the presence of from 0.05 to 20% by weight of an emulsifier, the percentages being based on the weight of the isomer mixture,(a) in a first stage at from 55.degree. to 100.degree. C. and a pH from 2 to 8 and then(b) in a second stage at from 10.degree. to 40.degree. C. and a pH of not less than 9.The methyl m-nitrobenzoate obtainable by the process of the invention is a useful starting material for the preparation of dyes and crop protection agents.

Abstract translation: 间硝基苯甲酸甲酯通过一种方法制备，其中异构体混合物在0.05至20重量％的乳化剂存在下，用10至1000重量％的水处理，百分比基于 异构体混合物，（a）在55℃至100℃的第一阶段和pH为2至8的第一阶段中，然后（b）在10至40℃的第二阶段中，并且pH值不低于 可通过本发明方法获得的间硝基苯甲酸甲酯是用于制备染料和作物保护剂的有用起始材料。

公开(公告)号：US4469901A

公开(公告)日：1984-09-04

申请号：US567791

申请日：1984-01-03

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/86 ,  C07C39/06 ,  C07C201/16 ,  C07C205/22

CPC classification number: C07C37/86 ,  C07C37/84 ,  C07C39/235

Abstract: A process is disclosed for separating 5-isopropyl-m-cresol from other isopropylated m-cresols by treating a mixture of the isopropylated m-cresols with a metal halide salt. The metal halide salt preferentially forms a complex with 5-isopropyl-m-cresol over other related closely-boiling isopropylated m-cresols in the mixture. The preferentially-formed complex of 5-isopropyl-m-cresol may then be isolated from the mixture and the complex decomposed to provide a product substantially enriched in, or substantially entirely composed of, 5-isopropyl-m-cresol. The process is particularly suitable for isolating 5-isopropyl-m-cresol from closely-boiling isomers, and di-isopropylated m-cresols.

Abstract translation: 公开了通过将异丙基化间甲酚与金属卤化物盐的混合物进行处理从其它异丙基化间甲酚中分离5-异丙基间甲酚的方法。 与其他相关的沸点相近的异丙基化间甲酚相比，金属卤化物盐与5-异丙基间甲酚优先形成络合物。 然后可以从混合物中分离出优先形成的5-异丙基间甲酚的复合物，并将络合物分解，得到基本上富含或完全由5-异丙基间甲酚组成的产物。 该方法特别适用于从紧密沸腾的异构体和二异丙基化的间甲酚中分离出5-异丙基间甲酚。