公开(公告)号：US11022578B2

公开(公告)日：2021-06-01

申请号：US17129902

申请日：2020-12-21

申请人： 2Pi-Sigma Corp.

发明人： Mehdi Hatamian

IPC分类号： G01N27/327 ,  G01N33/53 ,  B01L3/00

摘要： A lateral flow assay device comprising a conjugate pad for receiving a quantity of fluid; and a membrane comprising a test line for determining whether the fluid comprises a target analyte. In a first state of the lateral flow assay device, the lateral flow assay device is configured with a removable gap between the conjugate pad and the membrane which is substantially filled with air and prevents the fluid from flowing from the conjugate pad into the membrane. In a second state of the lateral flow assay device, the removable gap is removed from between the conjugate pad and the membrane causing the conjugate pad to come in contact with the membrane, allowing the fluid to flow from the conjugate pad into the membrane and the test line by capillary action.

公开(公告)号：US10914704B2

公开(公告)日：2021-02-09

申请号：US16986175

申请日：2020-08-05

申请人： 2Pi-Sigma Corp.

发明人： Mehdi Hatamian

IPC分类号： G01N27/327 ,  B01L3/00 ,  G01N33/53

摘要： A lateral flow assay device comprising a conjugate pad for receiving a quantity of fluid; and a membrane comprising a test line for determining whether the fluid comprises a target analyte. In a first state of the lateral flow assay device, the lateral flow assay device is configured with a removable gap between the conjugate pad and the membrane which is substantially filled with air and prevents the fluid from flowing from the conjugate pad into the membrane. In a second state of the lateral flow assay device, the removable gap is removed from between the conjugate pad and the membrane causing the conjugate pad to come in contact with the membrane, allowing the fluid to flow from the conjugate pad into the membrane and the test line by capillary action.

公开(公告)号：US10739297B2

公开(公告)日：2020-08-11

申请号：US16698788

申请日：2019-11-27

申请人： 2Pi-Sigma Corp.

发明人： Mehdi Hatamian

IPC分类号： G01N27/327 ,  B01L3/00 ,  G01N33/53

摘要： A lateral flow assay device comprising a conjugate pad for receiving a quantity of fluid; and a membrane comprising a test line for determining whether the fluid comprises a target analyte. In a first state of the lateral flow assay device, the lateral flow assay device is configured with a removable gap between the conjugate pad and the membrane which is substantially filled with air and prevents the fluid from flowing from the conjugate pad into the membrane. In a second state of the lateral flow assay device, the removable gap is removed from between the conjugate pad and the membrane causing the conjugate pad to come in contact with the membrane, allowing the fluid to flow from the conjugate pad into the membrane and the test line by capillary action.

公开(公告)号：US20200057086A1

公开(公告)日：2020-02-20

申请号：US16664746

申请日：2019-10-25

申请人： 2Pi-Sigma Corp.

发明人： Mehdi Hatamian

IPC分类号： G01N35/10 ,  G01N35/00 ,  G01N33/49

摘要： A sample collection and testing device for analyzing blood is provided that includes a controller, a fluid flow pathway, a pump configured to move fluid through the fluid pathway, and an optical fluid measurement element configured to measure a light intensity of the fluid in the fluid flow pathway. The controller is configured to: start the pump to move a blood sample in the fluid flow pathway, receive a signal from the optical fluid measurement element indicating a detection of a leading edge of the blood in the fluid flow pathway, stop the pump to stop the moving of the blood in the pathway, receive a plurality of light intensity measurements from the optical measurement element, each light intensity measurement measured at a corresponding point of time, and provide a mapping of the light intensity measurements into an indication of a coagulation of the blood sample over a time period.

公开(公告)号：US20200054260A1

公开(公告)日：2020-02-20

申请号：US16663711

申请日：2019-10-25

申请人： 2Pi-Sigma Corp.

发明人： Mehdi Hatamian

IPC分类号： A61B5/15

摘要： A test cartridge includes an adjustable lancet. The adjustable lancet is controlled by a controller. The adjustable lancet automatically detects a subject's finger, adjusts the lancet's height, pricks the finger to draw blood, moves a tube to collect the blood, moves the tube away from the finger, and empties the blood from the tube into a vial or receptacle. The adjustable lancet may include safety features to prevent the lancet to trigger when the subject's fingernail is facing the lancet, to control the amount that the lancet pierces the subject's finger, and/or to prevent the reuse of a test cartridge for multiple persons or multiple times by the same person. The adjustable lancet may include a massager wheel and/or a pressure bar to rub the subject's finger after the finger is pierced to facilitate drawing of the blood from the finger.