公开(公告)号：US3986005A

公开(公告)日：1976-10-12

申请号：US517061

申请日：1974-10-22

申请人： Akira Itoh

发明人： Akira Itoh

IPC分类号： G01C22/00

CPC分类号： G01C22/00

摘要： An odometer for an automobile comprises a drive gear having a couple of projections, a plurality of numbered wheels whose least significant digit wheel has an internal gear, and a cam disposed between the drive gear and the least significant digit wheel, whereby the cam engages with and disengages from the internal gear teeth as the couple of the projections abut against the cam in response to the rotating direction of the drive gear, thus preventing the reversing of the numbered wheels.

摘要翻译： 用于汽车的里程表包括具有一对突起的驱动齿轮，多个数字轮，其最低有效数字轮具有内齿轮，以及设置在驱动齿轮和最低有效数字轮之间的凸轮，由此凸轮与 并且当一对突起响应于驱动齿轮的旋转方向而抵靠凸轮时，与内齿轮齿脱离，从而防止编号的车轮的反转。

公开(公告)号：US08525064B2

公开(公告)日：2013-09-03

申请号：US12943092

申请日：2010-11-10

申请人： Akira Itoh ,  Yasuji Inobe ,  Hiroshi Adachi ,  Takeshi Oochi ,  Kazuhisa Ikuta ,  Michio Kameyama

发明人： Akira Itoh ,  Yasuji Inobe ,  Hiroshi Adachi ,  Takeshi Oochi ,  Kazuhisa Ikuta ,  Michio Kameyama

IPC分类号： B23H1/02 ,  B23H9/10 ,  B23H9/14

CPC分类号： B23H1/02

摘要： An electric discharge machine to process a work piece includes a plurality of electrodes, and a plurality of discharge power supply units. The plurality of electrodes generate a plurality of discharges with the work piece, respectively. The plurality of discharge power supply units apply voltages for the plurality of electrodes, respectively and independently.

摘要翻译： 用于处理工件的放电机包括多个电极和多个放电电源单元。 多个电极分别与工件产生多个放电。 多个放电电源单元分别独立地施加多个电极的电压。

公开(公告)号：US20080000627A1

公开(公告)日：2008-01-03

申请号：US11824526

申请日：2007-06-29

申请人： Kazue Noguchi ,  Masahiro Shimoya ,  Akira Itoh ,  Hiroyuki Genda

发明人： Kazue Noguchi ,  Masahiro Shimoya ,  Akira Itoh ,  Hiroyuki Genda

IPC分类号： F28F9/04

CPC分类号： F28D1/05366 ,  F28D2021/0084 ,  F28F3/042 ,  F28F9/0229 ,  F28F9/16 ,  Y10T29/49373

摘要： A heat exchanger has tubes for performing heat exchange between an internal fluid flowing inside of the tubes and an external fluid flowing outside of the tubes and a tank connected to the tubes. Each of the tubes has projections projecting from an outer surface thereof. The projections are arranged in a longitudinal direction of the tube such that grooves are provided between the adjacent projections as external fluid passage portions. The tank has tube insertion portions defining openings into which ends of the tubes are inserted. Each of the tube insertion portions is configured such that a perimeter surface defining the opening thereof entirely covers at least one external fluid passage portion of the tube.

摘要翻译： 热交换器具有用于在管内流动的内部流体和流过管外部的外部流体之间进行热交换的管和连接到管的罐。 每个管具有从其外表面突出的突起。 突起沿管的纵向方向布置，使得在相邻的突起之间设置槽作为外部流体通道部分。 罐具有限定开口的管插入部分，管的端部插入其中。 每个管插入部分构造成使得限定其开口的周边表面完全覆盖管的至少一个外部流体通道部分。

公开(公告)号：US20070186585A1

公开(公告)日：2007-08-16

申请号：US10598801

申请日：2005-03-25

申请人： Tamotsu Matsumura ,  Yoshinori Kawabuchi ,  Akira Itoh

发明人： Tamotsu Matsumura ,  Yoshinori Kawabuchi ,  Akira Itoh

IPC分类号： A44C17/00

CPC分类号： A44C17/001

摘要： An oval-cut diamond comprises a girdle having a contour line in an oval or oval-like shape, a crown above the girdle having an octagonal table facet on a top of it and a pavilion below the girdle. The girdle is of a ratio (b/a) of a short radius to a long radius of 0.6 or more, in which a radius in long axis direction is “a”, and a radius in short axis direction is “b”. A pair of pavilion main facets positioned opposite to each other with respect to a central axis has a pair of crown main facets or star facets facing the pair of pavilion main facets through the girdle. The two pavilion main facets, the two crown main facets or star facets and the table facet have a common vertical plane within the facets so that brilliancy of reflection lights coming out of the table facet and crown facets is enhanced.

摘要翻译： 椭圆形切割金刚石包括具有椭圆形或椭圆形形状的轮廓线的腰带，腰带上方的冠部具有在其顶部上的八边形台面和在腰带下方的亭子。 腰围的长径方向的半径为“a”，短轴方向的半径为“b”的短半径与长半径的比率（b / a）为0.6以上。 相对于中心轴线彼此相对设置的一对亭子主面具有一对冠面主要小面或通过腰带面对一对亭子主要小面的星形面。 两个亭子的主要面，两个皇冠主要小面或星形刻面和桌面在面内具有一个共同的垂直平面，从而增强了从桌面和表冠面出来的反射光的辉煌。

公开(公告)号：US07238777B2

公开(公告)日：2007-07-03

申请号：US10270555

申请日：2002-10-16

申请人： Akira Itoh ,  Yutaka Hanazono ,  Takashi Okada ,  Keiya Ozawa

发明人： Akira Itoh ,  Yutaka Hanazono ,  Takashi Okada ,  Keiya Ozawa

IPC分类号： C07K1/00

CPC分类号： C07K16/2896 ,  C07K2317/622 ,  C07K2319/00 ,  C12N2799/022

摘要： The object of the present invention is to provide an agent for specific adsorption of type 5 adenoviral vector to undifferentiated blood cells which enables infection with a viral concentration that does not impart toxicity to undifferentiated blood cells, without requiring the construction of a new viral genome, or special modification of viral particles such as biotination, etc. The above objective has been achieved by providing a polypeptide which has affinity for both adenovirus and undifferentiated blood cells. Use of the polypeptide of the present invention enables improved efficiency of adenoviral vector-mediated gene transfer of any gene to undifferentiated blood cells, and there is provided a method of introducing any gene for which transient expression in these cells is desired. In particular, the method is useful for intracellular DNA recombination by transiently expressing site-specific recombinase, and for induction into any cells of different lines by transient expression of master genes.

摘要翻译： 本发明的目的是提供一种用于特异性吸附5型腺病毒载体的未分化血细胞的试剂，其能够以不对未分化血细胞赋予毒性的病毒浓度进行感染，而不需要构建新的病毒基因组， 或特异性修饰病毒颗粒如生物素化等。上述目的已通过提供对腺病毒和未分化血细胞具有亲和力的多肽来实现。 使用本发明的多肽能够提高任何基因向未分化血细胞的腺病毒载体介导的基因转移的效率，并且提供了引入其中期望这些细胞中瞬时表达的任何基因的方法。 特别地，该方法对于通过瞬时表达位点特异性重组酶的细胞内DNA重组以及通过主基因的瞬时表达诱导到不同细胞系的任何细胞中是有用的。

公开(公告)号：US07141379B2

公开(公告)日：2006-11-28

申请号：US09995593

申请日：2001-11-29

申请人： Seiji Sakano ,  Akira Itoh

发明人： Seiji Sakano ,  Akira Itoh

IPC分类号： G01N33/53

CPC分类号： C07K14/4703 ,  A61K38/00 ,  Y02A50/473

摘要： A method for suppressing differentiation of undifferentiated blood cells in vivo by contacting the cells in vitro with a serrate-1 peptide, thereby suppressing differentiation of the cells.

摘要翻译： 通过使体外细胞与锯齿-1肽接触来抑制体内未分化血细胞的分化的方法，由此抑制细胞的分化。

公开(公告)号：US07138276B2

公开(公告)日：2006-11-21

申请号：US10219248

申请日：2002-08-16

申请人： Seiji Sakano ,  Akira Itoh

发明人： Seiji Sakano ,  Akira Itoh

IPC分类号： C12N5/08 ,  A61K38/18

CPC分类号： C07K14/47 ,  A61K38/00

摘要： A novel human serrate-2 polypeptide consisting of a polypeptide containing the amino acid sequence described in SEQ ID NO:1 in the Sequence Listing and having the effect of regulating the differentiation of undifferentiated cells involving stem cells; its gene; a process for producing the same; and an antibody specifically recognizing the polypeptide.

摘要翻译： 一种由包含序列表中SEQ ID NO：1所述的氨基酸序列的多肽组成并且具有调节涉及干细胞的未分化细胞分化的作用的新型人锯状细胞-2多肽; 其基因; 其制造方法; 和特异性识别多肽的抗体。

公开(公告)号：US07111664B2

公开(公告)日：2006-09-26

申请号：US11083791

申请日：2005-03-18

申请人： Akira Itoh ,  Kiyoshi Sawada

发明人： Akira Itoh ,  Kiyoshi Sawada

IPC分类号： B22D17/12 ,  B22D18/02 ,  B22D27/11

CPC分类号： B22D17/2069 ,  B22D17/12 ,  B22D17/2023 ,  B22D17/203

摘要： A molding device includes a lower mold unit and an upper mold unit. A molding cavity is defined between the mold units. The lower mold unit has a storing chamber connected to the molding cavity. The upper mold unit has a damper chamber connected to the molding cavity. A pressurizing rod is inserted into the damper chamber. The pressurizing rod is actuated by a cylinder. When a pushing rod pushes molten metal in the storing chamber to the cavity, an excess amount of the molten metal enters the damper chamber. Therefore, the molding operation is reliably performed even if an excessive amount of molten metal is injected into the storing chamber. Further, the pressurizing rod pressurizes the excess amount of metal in the damper chamber.

摘要翻译： 成型装置包括下模单元和上模单元。 在模具单元之间限定模制腔。 下模具单元具有连接到模腔的储存室。 上模具单元具有连接到模腔的阻尼室。 一个加压杆插入阻尼室。 加压杆由气缸驱动。 当推杆将储存室中的熔融金属推到空腔时，多余的熔融金属进入阻尼室。 因此，即使过量的熔融金属被注入到储存室中，也可以可靠地进行成型操作。 此外，加压杆对阻尼室中的过量金属加压。

公开(公告)号：US20050205231A1

公开(公告)日：2005-09-22

申请号：US11083791

申请日：2005-03-18

申请人： Akira Itoh ,  Kiyoshi Sawada

发明人： Akira Itoh ,  Kiyoshi Sawada

IPC分类号： B22D17/22 ,  B22D17/12 ,  B22D17/20 ,  B22D17/32 ,  B22D35/00

CPC分类号： B22D17/2069 ,  B22D17/12 ,  B22D17/2023 ,  B22D17/203

摘要： A molding device includes a lower mold unit and an upper mold unit. A molding cavity is defined between the mold units. The lower mold unit has a storing chamber connected to the molding cavity. The upper mold unit has a damper chamber connected to the molding cavity. A pressurizing rod is inserted into the damper chamber. The pressurizing rod is actuated by a cylinder. When a pushing rod pushes molten metal in the storing chamber to the cavity, an excess amount of the molten metal enters the damper chamber. Therefore, the molding operation is reliably performed even if an excessive amount of molten metal is injected into the storing chamber. Further, the pressurizing rod pressurizes the excess amount of metal in the damper chamber.

摘要翻译： 成型装置包括下模单元和上模单元。 在模具单元之间限定模制腔。 下模具单元具有连接到模腔的储存室。 上模具单元具有连接到模腔的阻尼室。 一个加压杆插入阻尼室。 加压杆由气缸驱动。 当推杆将储存室中的熔融金属推到空腔时，多余的熔融金属进入阻尼室。 因此，即使过量的熔融金属被注入到储存室中，也可以可靠地进行成型操作。 此外，加压杆对阻尼室中的过量金属加压。

公开(公告)号：US06795762B2

公开(公告)日：2004-09-21

申请号：US10316912

申请日：2002-12-12

申请人： Akira Itoh ,  Masahide Iwazawa ,  Kiyotaka Iwata ,  Yasushi Yamada

发明人： Akira Itoh ,  Masahide Iwazawa ,  Kiyotaka Iwata ,  Yasushi Yamada

IPC分类号： G06F1700

CPC分类号： B62D5/049 ,  B62D5/0484

摘要： A steering apparatus controller for an electric power steering apparatus, which includes an electric motor for generating assist torque for assisting steering of a steering wheel and the steering apparatus controller is designed to execute a feedback control of the applied drive voltage to the electric motor based on the detection result of the actual current that flows through the motor. A sensor detects the actual current to produce the detection result. When detecting an abnormal decrease of the drive voltage of the sensor, a voltage controller maintains the applied voltage to the electric motor at the voltage at a predetermined time before the drive voltage abnormally decreased.

摘要翻译： 一种用于电动助力转向装置的转向装置控制器，其包括用于产生用于辅助方向盘的转向的辅助转矩的电动机和所述转向装置控制器，被设计成基于对所述电动机施加的驱动电压的反馈控制 流过电机的实际电流的检测结果。 传感器检测实际电流以产生检测结果。 当检测到传感器的驱动电压的异常降低时，电压控制器在驱动电压异常降低之前的预定时间将电动机的施加电压保持在电动机上。